JP2006522336A5 - - Google Patents
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- Publication number
- JP2006522336A5 JP2006522336A5 JP2006509274A JP2006509274A JP2006522336A5 JP 2006522336 A5 JP2006522336 A5 JP 2006522336A5 JP 2006509274 A JP2006509274 A JP 2006509274A JP 2006509274 A JP2006509274 A JP 2006509274A JP 2006522336 A5 JP2006522336 A5 JP 2006522336A5
- Authority
- JP
- Japan
- Prior art keywords
- nfdp
- detecting
- antibody
- sample
- kit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 7
- 239000000523 sample Substances 0.000 claims 7
- 208000028389 Nerve injury Diseases 0.000 claims 5
- 230000008764 nerve damage Effects 0.000 claims 5
- 238000002965 ELISA Methods 0.000 claims 2
- 239000012472 biological sample Substances 0.000 claims 2
- 239000003153 chemical reaction reagent Substances 0.000 claims 2
- 102000008763 Neurofilament Proteins Human genes 0.000 claims 1
- 108010088373 Neurofilament Proteins Proteins 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 1
- 239000003593 chromogenic compound Substances 0.000 claims 1
- 230000002596 correlated effect Effects 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 238000003018 immunoassay Methods 0.000 claims 1
- 238000003119 immunoblot Methods 0.000 claims 1
- 230000000951 immunodiffusion Effects 0.000 claims 1
- 238000001114 immunoprecipitation Methods 0.000 claims 1
- 210000005044 neurofilament Anatomy 0.000 claims 1
- 210000002381 plasma Anatomy 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 238000003127 radioimmunoassay Methods 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45928603P | 2003-03-31 | 2003-03-31 | |
| PCT/US2004/009114 WO2004091379A2 (en) | 2003-03-31 | 2004-03-26 | Assessing neuronal damage from blood samples |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006522336A JP2006522336A (ja) | 2006-09-28 |
| JP2006522336A5 true JP2006522336A5 (enExample) | 2007-04-19 |
| JP4557971B2 JP4557971B2 (ja) | 2010-10-06 |
Family
ID=33299668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006509274A Expired - Fee Related JP4557971B2 (ja) | 2003-03-31 | 2004-03-26 | 血液試料からの神経損傷の評価 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20040241762A1 (enExample) |
| EP (1) | EP1613204B1 (enExample) |
| JP (1) | JP4557971B2 (enExample) |
| AT (1) | ATE440286T1 (enExample) |
| AU (1) | AU2004229317B2 (enExample) |
| CA (1) | CA2520945C (enExample) |
| DE (1) | DE602004022645D1 (enExample) |
| DK (1) | DK1613204T3 (enExample) |
| ES (1) | ES2332136T3 (enExample) |
| WO (1) | WO2004091379A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005113798A2 (en) * | 2004-04-15 | 2005-12-01 | University Of Florida Research Foundation, Inc. | Proteolytic markers as diagnostic biomarkers for cancer, organ injury and muscle rehabilitation/exercise overtraining |
| US20070276275A1 (en) * | 2006-05-24 | 2007-11-29 | University Of Miami | Screening method and system to estimate the severity of injury in critically ill patients |
| JPWO2008078809A1 (ja) * | 2006-12-27 | 2010-04-30 | 独立行政法人科学技術振興機構 | 鳥類抗体を使用する免疫学的検出方法 |
| US20140038834A1 (en) * | 2010-07-07 | 2014-02-06 | Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patiëntenzorg | Novel biomarkers for detecting neuronal loss |
| EP3129780A4 (en) * | 2014-04-07 | 2017-12-13 | Iron Horse Diagnostics Inc. | Traumatic brain injury and neurodegenerative biomarkers, methods, and systems |
| CN112823048A (zh) * | 2018-07-27 | 2021-05-18 | 维拉维斯公司 | 消除和富集的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LU86652A1 (de) * | 1986-11-10 | 1988-06-13 | Progen Biotechnik Gmbh | Verfahren zum auffinden von gewebslaesionen |
| DE68927459T2 (de) * | 1988-12-21 | 1997-04-24 | Gen Hospital Corp | Nachweis einer neurologischen Krankheit oder einer Funktionsstörung |
| US5595722A (en) * | 1993-01-28 | 1997-01-21 | Neorx Corporation | Method for identifying an agent which increases TGF-beta levels |
| GB9719879D0 (en) * | 1997-09-19 | 1997-11-19 | Neuropa Ltd | Protein |
| US6589746B1 (en) * | 1999-10-21 | 2003-07-08 | University Of Cincinnati | Method of detecting axonally-derived protein tau in patients with traumatic CNS injury |
-
2004
- 2004-03-26 ES ES04758954T patent/ES2332136T3/es not_active Expired - Lifetime
- 2004-03-26 JP JP2006509274A patent/JP4557971B2/ja not_active Expired - Fee Related
- 2004-03-26 AT AT04758954T patent/ATE440286T1/de not_active IP Right Cessation
- 2004-03-26 CA CA2520945A patent/CA2520945C/en not_active Expired - Fee Related
- 2004-03-26 EP EP04758954A patent/EP1613204B1/en not_active Expired - Lifetime
- 2004-03-26 DK DK04758954T patent/DK1613204T3/da active
- 2004-03-26 DE DE602004022645T patent/DE602004022645D1/de not_active Expired - Lifetime
- 2004-03-26 AU AU2004229317A patent/AU2004229317B2/en not_active Ceased
- 2004-03-26 US US10/810,388 patent/US20040241762A1/en not_active Abandoned
- 2004-03-26 WO PCT/US2004/009114 patent/WO2004091379A2/en not_active Ceased
-
2010
- 2010-03-17 US US12/726,064 patent/US20100184105A1/en not_active Abandoned
-
2014
- 2014-11-21 US US14/550,240 patent/US20160349272A1/en not_active Abandoned
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