JP2006522149A5 - - Google Patents
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- Publication number
- JP2006522149A5 JP2006522149A5 JP2006509657A JP2006509657A JP2006522149A5 JP 2006522149 A5 JP2006522149 A5 JP 2006522149A5 JP 2006509657 A JP2006509657 A JP 2006509657A JP 2006509657 A JP2006509657 A JP 2006509657A JP 2006522149 A5 JP2006522149 A5 JP 2006522149A5
- Authority
- JP
- Japan
- Prior art keywords
- implantable device
- dopamine agonist
- matrix
- inflammatory agent
- implantable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003136 dopamine receptor stimulating agent Substances 0.000 claims 37
- 239000011159 matrix material Substances 0.000 claims 20
- 239000002260 anti-inflammatory agent Substances 0.000 claims 13
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 13
- 241000124008 Mammalia Species 0.000 claims 11
- 229920000642 polymer Polymers 0.000 claims 10
- 239000005038 ethylene vinyl acetate Substances 0.000 claims 9
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 claims 9
- 229960004046 apomorphine Drugs 0.000 claims 8
- VMWNQDUVQKEIOC-CYBMUJFWSA-N apomorphine Chemical compound C([C@H]1N(C)CC2)C3=CC=C(O)C(O)=C3C3=C1C2=CC=C3 VMWNQDUVQKEIOC-CYBMUJFWSA-N 0.000 claims 8
- 230000002459 sustained effect Effects 0.000 claims 8
- 230000009972 noncorrosive effect Effects 0.000 claims 5
- 230000036470 plasma concentration Effects 0.000 claims 5
- BKRGVLQUQGGVSM-KBXCAEBGSA-N Revanil Chemical compound C1=CC(C=2[C@H](N(C)C[C@H](C=2)NC(=O)N(CC)CC)C2)=C3C2=CNC3=C1 BKRGVLQUQGGVSM-KBXCAEBGSA-N 0.000 claims 4
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 claims 4
- 229960002802 bromocriptine Drugs 0.000 claims 4
- OZVBMTJYIDMWIL-AYFBDAFISA-N bromocriptine Chemical compound C1=CC(C=2[C@H](N(C)C[C@@H](C=2)C(=O)N[C@]2(C(=O)N3[C@H](C(N4CCC[C@H]4[C@]3(O)O2)=O)CC(C)C)C(C)C)C2)=C3C2=C(Br)NC3=C1 OZVBMTJYIDMWIL-AYFBDAFISA-N 0.000 claims 4
- 238000001727 in vivo Methods 0.000 claims 4
- 229960003587 lisuride Drugs 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 229960004851 pergolide Drugs 0.000 claims 4
- YEHCICAEULNIGD-MZMPZRCHSA-N pergolide Chemical compound C1=CC([C@H]2C[C@@H](CSC)CN([C@@H]2C2)CCC)=C3C2=CNC3=C1 YEHCICAEULNIGD-MZMPZRCHSA-N 0.000 claims 4
- 229960003089 pramipexole Drugs 0.000 claims 4
- FASDKYOPVNHBLU-ZETCQYMHSA-N pramipexole Chemical compound C1[C@@H](NCCC)CCC2=C1SC(N)=N2 FASDKYOPVNHBLU-ZETCQYMHSA-N 0.000 claims 4
- 229960001879 ropinirole Drugs 0.000 claims 4
- UHSKFQJFRQCDBE-UHFFFAOYSA-N ropinirole Chemical compound CCCN(CCC)CCC1=CC=CC2=C1CC(=O)N2 UHSKFQJFRQCDBE-UHFFFAOYSA-N 0.000 claims 4
- 229960003179 rotigotine Drugs 0.000 claims 4
- KFQYTPMOWPVWEJ-INIZCTEOSA-N rotigotine Chemical compound CCCN([C@@H]1CC2=CC=CC(O)=C2CC1)CCC1=CC=CS1 KFQYTPMOWPVWEJ-INIZCTEOSA-N 0.000 claims 4
- 239000003963 antioxidant agent Substances 0.000 claims 3
- 230000003078 antioxidant effect Effects 0.000 claims 3
- 238000001125 extrusion Methods 0.000 claims 3
- 238000000338 in vitro Methods 0.000 claims 3
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims 3
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 3
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical group C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 claims 2
- 206010044565 Tremor Diseases 0.000 claims 2
- 230000001387 anti-histamine Effects 0.000 claims 2
- 239000000739 antihistaminic agent Substances 0.000 claims 2
- 238000001802 infusion Methods 0.000 claims 2
- 125000002345 steroid group Chemical group 0.000 claims 2
- 208000010228 Erectile Dysfunction Diseases 0.000 claims 1
- 208000018737 Parkinson disease Diseases 0.000 claims 1
- 208000005793 Restless legs syndrome Diseases 0.000 claims 1
- 210000000683 abdominal cavity Anatomy 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 201000001881 impotence Diseases 0.000 claims 1
- 239000011148 porous material Substances 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- 238000010254 subcutaneous injection Methods 0.000 claims 1
- 239000007929 subcutaneous injection Substances 0.000 claims 1
- 230000009885 systemic effect Effects 0.000 claims 1
- 239000003053 toxin Substances 0.000 claims 1
- 231100000765 toxin Toxicity 0.000 claims 1
- 108700012359 toxins Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45931503P | 2003-03-31 | 2003-03-31 | |
| US60/459,315 | 2003-03-31 | ||
| PCT/US2004/010270 WO2004089375A1 (en) | 2003-03-31 | 2004-03-31 | Implantable polymeric device for sustained release of dopamine agonist |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011023211A Division JP5608581B2 (ja) | 2003-03-31 | 2011-02-04 | ドパミンアゴニストの徐放のための移植可能なポリマーデバイス |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006522149A JP2006522149A (ja) | 2006-09-28 |
| JP2006522149A5 true JP2006522149A5 (https=) | 2007-05-10 |
| JP5064794B2 JP5064794B2 (ja) | 2012-10-31 |
Family
ID=33159641
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006509657A Expired - Fee Related JP5064794B2 (ja) | 2003-03-31 | 2004-03-31 | ドパミンアゴニストの徐放のための移植可能なポリマーデバイス |
| JP2011023211A Expired - Fee Related JP5608581B2 (ja) | 2003-03-31 | 2011-02-04 | ドパミンアゴニストの徐放のための移植可能なポリマーデバイス |
| JP2013147574A Pending JP2013213056A (ja) | 2003-03-31 | 2013-07-16 | ドパミンアゴニストの徐放のための移植可能なポリマーデバイス |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011023211A Expired - Fee Related JP5608581B2 (ja) | 2003-03-31 | 2011-02-04 | ドパミンアゴニストの徐放のための移植可能なポリマーデバイス |
| JP2013147574A Pending JP2013213056A (ja) | 2003-03-31 | 2013-07-16 | ドパミンアゴニストの徐放のための移植可能なポリマーデバイス |
Country Status (20)
| Country | Link |
|---|---|
| US (5) | US20050031667A1 (https=) |
| EP (1) | EP1610791B1 (https=) |
| JP (3) | JP5064794B2 (https=) |
| KR (1) | KR101152183B1 (https=) |
| CN (2) | CN1777426A (https=) |
| AT (1) | ATE499100T1 (https=) |
| AU (1) | AU2004228017C1 (https=) |
| CA (1) | CA2520613C (https=) |
| CY (1) | CY1111465T1 (https=) |
| DE (1) | DE602004031512D1 (https=) |
| DK (1) | DK1610791T3 (https=) |
| ES (1) | ES2359977T3 (https=) |
| IL (1) | IL171115A (https=) |
| MX (1) | MXPA05010450A (https=) |
| NZ (1) | NZ542548A (https=) |
| PL (1) | PL1610791T3 (https=) |
| PT (1) | PT1610791E (https=) |
| SI (1) | SI1610791T1 (https=) |
| WO (1) | WO2004089375A1 (https=) |
| ZA (1) | ZA200507877B (https=) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10043321B4 (de) * | 2000-08-24 | 2005-07-28 | Neurobiotec Gmbh | Verwendung eines transdermalen therapeutischen Systems zur Behandlung der Parkinsonschen Krankheit, zur Behandlung und Prävention des prämenstruellen Syndroms und zur Lactationshemmung |
| DE10053397A1 (de) * | 2000-10-20 | 2002-05-02 | Schering Ag | Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen |
| DE10064453A1 (de) * | 2000-12-16 | 2002-07-04 | Schering Ag | Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen |
| US20060281797A1 (en) * | 2001-12-11 | 2006-12-14 | University Of Virginia Patent Foundation | Neurorestoration with R(+) Pramipexole |
| ES2432527T3 (es) * | 2001-12-11 | 2013-12-04 | University Of Virginia Patent Foundation | Uso de pramipexol para tratar la esclerosis lateral amiotrófica |
| SI2561860T1 (en) * | 2002-05-31 | 2018-05-31 | Titan Pharmaceuticals, Inc. | An implantable polymeric device for prolonged release of buprenorphine |
| PT1610791E (pt) | 2003-03-31 | 2011-05-23 | Titan Pharmaceuticals Inc | Dispositivo polim?rico implant?vel para liberta??o sustentada de agonista da dopamina |
| CA2526101A1 (en) * | 2003-05-30 | 2004-12-23 | Titan Pharmaceuticals, Inc. | Implantable polymeric device for sustained release of nalmefene |
| WO2006078320A2 (en) | 2004-08-04 | 2006-07-27 | Brookwood Pharmaceuticals, Inc. | Methods for manufacturing delivery devices and devices thereof |
| US8691277B2 (en) | 2004-09-21 | 2014-04-08 | Shandong Luye Pharmaceutical Co., Ltd. | Long acting sustained-release formulation containing dopamine receptor agonist and the preparation method thereof |
| JP2008536866A (ja) * | 2005-04-15 | 2008-09-11 | ボード、オブ、トラスティーズ、オブ、ミシガン、ステイト、ユニバーシティ | アミン作動性医薬組成物および方法 |
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| PT2010184E (pt) * | 2006-04-06 | 2013-04-03 | Nupathe Inc | Implantes para o tratamento dos estados associados à dopamina |
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| WO2007139744A2 (en) * | 2006-05-23 | 2007-12-06 | Titan Pharmaceuticals, Inc. | Implantable polymeric device for sustained release of buprenorphine with minimal initial burst |
| US8524695B2 (en) * | 2006-12-14 | 2013-09-03 | Knopp Neurosciences, Inc. | Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same |
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| EP3038467B1 (en) | 2013-08-13 | 2020-07-29 | Knopp Biosciences LLC | Compositions and methods for treating plasma cell disorders and b-cell prolymphocytic disorders |
| DK3033081T3 (da) | 2013-08-13 | 2021-05-31 | Knopp Biosciences Llc | Sammensætninger og fremgangsmåder til behandling af kronisk urticaria |
| US10698930B2 (en) | 2013-08-22 | 2020-06-30 | Sensoriant, Inc. | Assignment of application (apps) and relevant services to specific locations, dates and times |
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| MX2020012459A (es) | 2018-05-24 | 2021-04-28 | Celanese Eva Performance Polymers Llc | Dispositivo implantable para liberacion sostenida de un compuesto de farmaco macromolecular. |
| KR20260007295A (ko) | 2018-05-24 | 2026-01-13 | 셀라니즈 이브이에이 퍼포먼스 폴리머스 엘엘씨 | 거대 분자 약물 화합물의 지속적인 방출을 위한 이식가능 장치 |
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| CN116256439B (zh) * | 2021-12-10 | 2025-11-07 | 远大医药（中国）有限公司 | Hplc检测盐酸多巴胺注射液中焦亚硫酸钠含量的方法 |
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2004
- 2004-03-31 PT PT04758809T patent/PT1610791E/pt unknown
- 2004-03-31 CA CA2520613A patent/CA2520613C/en not_active Expired - Lifetime
- 2004-03-31 ES ES04758809T patent/ES2359977T3/es not_active Expired - Lifetime
- 2004-03-31 US US10/815,481 patent/US20050031667A1/en not_active Abandoned
- 2004-03-31 DE DE602004031512T patent/DE602004031512D1/de not_active Expired - Lifetime
- 2004-03-31 CN CNA2004800110608A patent/CN1777426A/zh active Pending
- 2004-03-31 JP JP2006509657A patent/JP5064794B2/ja not_active Expired - Fee Related
- 2004-03-31 MX MXPA05010450A patent/MXPA05010450A/es active IP Right Grant
- 2004-03-31 EP EP04758809A patent/EP1610791B1/en not_active Expired - Lifetime
- 2004-03-31 DK DK04758809.0T patent/DK1610791T3/da active
- 2004-03-31 KR KR1020057018582A patent/KR101152183B1/ko not_active Expired - Fee Related
- 2004-03-31 CN CN201210167123.5A patent/CN102772357B/zh not_active Expired - Lifetime
- 2004-03-31 SI SI200431641T patent/SI1610791T1/sl unknown
- 2004-03-31 AU AU2004228017A patent/AU2004228017C1/en not_active Ceased
- 2004-03-31 AT AT04758809T patent/ATE499100T1/de active
- 2004-03-31 WO PCT/US2004/010270 patent/WO2004089375A1/en not_active Ceased
- 2004-03-31 ZA ZA200507877A patent/ZA200507877B/en unknown
- 2004-03-31 NZ NZ542548A patent/NZ542548A/en not_active IP Right Cessation
- 2004-03-31 PL PL04758809T patent/PL1610791T3/pl unknown
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2005
- 2005-09-26 IL IL171115A patent/IL171115A/en active IP Right Grant
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2008
- 2008-05-12 US US12/119,334 patent/US20080311171A1/en not_active Abandoned
- 2008-12-22 US US12/341,766 patent/US20090162412A1/en not_active Abandoned
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2011
- 2011-02-04 JP JP2011023211A patent/JP5608581B2/ja not_active Expired - Fee Related
- 2011-05-17 CY CY20111100471T patent/CY1111465T1/el unknown
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2012
- 2012-06-15 US US13/525,193 patent/US8852623B2/en not_active Expired - Lifetime
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2013
- 2013-07-16 JP JP2013147574A patent/JP2013213056A/ja active Pending
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2014
- 2014-10-03 US US14/506,426 patent/US9278163B2/en not_active Expired - Fee Related
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