JP2006522149A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2006522149A5 JP2006522149A5 JP2006509657A JP2006509657A JP2006522149A5 JP 2006522149 A5 JP2006522149 A5 JP 2006522149A5 JP 2006509657 A JP2006509657 A JP 2006509657A JP 2006509657 A JP2006509657 A JP 2006509657A JP 2006522149 A5 JP2006522149 A5 JP 2006522149A5
- Authority
- JP
- Japan
- Prior art keywords
- implantable device
- dopamine agonist
- matrix
- inflammatory agent
- implantable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003136 dopamine receptor stimulating agent Substances 0.000 claims 37
- 239000011159 matrix material Substances 0.000 claims 20
- 239000002260 anti-inflammatory agent Substances 0.000 claims 13
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 13
- 241000124008 Mammalia Species 0.000 claims 11
- 229920000642 polymer Polymers 0.000 claims 10
- 239000005038 ethylene vinyl acetate Substances 0.000 claims 9
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 claims 9
- 229960004046 apomorphine Drugs 0.000 claims 8
- VMWNQDUVQKEIOC-CYBMUJFWSA-N apomorphine Chemical compound C([C@H]1N(C)CC2)C3=CC=C(O)C(O)=C3C3=C1C2=CC=C3 VMWNQDUVQKEIOC-CYBMUJFWSA-N 0.000 claims 8
- 230000002459 sustained effect Effects 0.000 claims 8
- 230000009972 noncorrosive effect Effects 0.000 claims 5
- 230000036470 plasma concentration Effects 0.000 claims 5
- BKRGVLQUQGGVSM-KBXCAEBGSA-N Revanil Chemical compound C1=CC(C=2[C@H](N(C)C[C@H](C=2)NC(=O)N(CC)CC)C2)=C3C2=CNC3=C1 BKRGVLQUQGGVSM-KBXCAEBGSA-N 0.000 claims 4
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 claims 4
- 229960002802 bromocriptine Drugs 0.000 claims 4
- OZVBMTJYIDMWIL-AYFBDAFISA-N bromocriptine Chemical compound C1=CC(C=2[C@H](N(C)C[C@@H](C=2)C(=O)N[C@]2(C(=O)N3[C@H](C(N4CCC[C@H]4[C@]3(O)O2)=O)CC(C)C)C(C)C)C2)=C3C2=C(Br)NC3=C1 OZVBMTJYIDMWIL-AYFBDAFISA-N 0.000 claims 4
- 238000001727 in vivo Methods 0.000 claims 4
- 229960003587 lisuride Drugs 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 229960004851 pergolide Drugs 0.000 claims 4
- YEHCICAEULNIGD-MZMPZRCHSA-N pergolide Chemical compound C1=CC([C@H]2C[C@@H](CSC)CN([C@@H]2C2)CCC)=C3C2=CNC3=C1 YEHCICAEULNIGD-MZMPZRCHSA-N 0.000 claims 4
- 229960003089 pramipexole Drugs 0.000 claims 4
- FASDKYOPVNHBLU-ZETCQYMHSA-N pramipexole Chemical compound C1[C@@H](NCCC)CCC2=C1SC(N)=N2 FASDKYOPVNHBLU-ZETCQYMHSA-N 0.000 claims 4
- 229960001879 ropinirole Drugs 0.000 claims 4
- UHSKFQJFRQCDBE-UHFFFAOYSA-N ropinirole Chemical compound CCCN(CCC)CCC1=CC=CC2=C1CC(=O)N2 UHSKFQJFRQCDBE-UHFFFAOYSA-N 0.000 claims 4
- 229960003179 rotigotine Drugs 0.000 claims 4
- KFQYTPMOWPVWEJ-INIZCTEOSA-N rotigotine Chemical compound CCCN([C@@H]1CC2=CC=CC(O)=C2CC1)CCC1=CC=CS1 KFQYTPMOWPVWEJ-INIZCTEOSA-N 0.000 claims 4
- 239000003963 antioxidant agent Substances 0.000 claims 3
- 230000003078 antioxidant effect Effects 0.000 claims 3
- 238000001125 extrusion Methods 0.000 claims 3
- 238000000338 in vitro Methods 0.000 claims 3
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims 3
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 3
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical group C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 claims 2
- 206010044565 Tremor Diseases 0.000 claims 2
- 230000001387 anti-histamine Effects 0.000 claims 2
- 239000000739 antihistaminic agent Substances 0.000 claims 2
- 238000001802 infusion Methods 0.000 claims 2
- 125000002345 steroid group Chemical group 0.000 claims 2
- 208000010228 Erectile Dysfunction Diseases 0.000 claims 1
- 208000018737 Parkinson disease Diseases 0.000 claims 1
- 208000005793 Restless legs syndrome Diseases 0.000 claims 1
- 210000000683 abdominal cavity Anatomy 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 201000001881 impotence Diseases 0.000 claims 1
- 239000011148 porous material Substances 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- 238000010254 subcutaneous injection Methods 0.000 claims 1
- 239000007929 subcutaneous injection Substances 0.000 claims 1
- 230000009885 systemic effect Effects 0.000 claims 1
- 239000003053 toxin Substances 0.000 claims 1
- 231100000765 toxin Toxicity 0.000 claims 1
- 108700012359 toxins Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45931503P | 2003-03-31 | 2003-03-31 | |
| US60/459,315 | 2003-03-31 | ||
| PCT/US2004/010270 WO2004089375A1 (en) | 2003-03-31 | 2004-03-31 | Implantable polymeric device for sustained release of dopamine agonist |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011023211A Division JP5608581B2 (ja) | 2003-03-31 | 2011-02-04 | ドパミンアゴニストの徐放のための移植可能なポリマーデバイス |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006522149A JP2006522149A (ja) | 2006-09-28 |
| JP2006522149A5 true JP2006522149A5 (https=) | 2007-05-10 |
| JP5064794B2 JP5064794B2 (ja) | 2012-10-31 |
Family
ID=33159641
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006509657A Expired - Fee Related JP5064794B2 (ja) | 2003-03-31 | 2004-03-31 | ドパミンアゴニストの徐放のための移植可能なポリマーデバイス |
| JP2011023211A Expired - Fee Related JP5608581B2 (ja) | 2003-03-31 | 2011-02-04 | ドパミンアゴニストの徐放のための移植可能なポリマーデバイス |
| JP2013147574A Pending JP2013213056A (ja) | 2003-03-31 | 2013-07-16 | ドパミンアゴニストの徐放のための移植可能なポリマーデバイス |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011023211A Expired - Fee Related JP5608581B2 (ja) | 2003-03-31 | 2011-02-04 | ドパミンアゴニストの徐放のための移植可能なポリマーデバイス |
| JP2013147574A Pending JP2013213056A (ja) | 2003-03-31 | 2013-07-16 | ドパミンアゴニストの徐放のための移植可能なポリマーデバイス |
Country Status (20)
| Country | Link |
|---|---|
| US (5) | US20050031667A1 (https=) |
| EP (1) | EP1610791B1 (https=) |
| JP (3) | JP5064794B2 (https=) |
| KR (1) | KR101152183B1 (https=) |
| CN (2) | CN102772357B (https=) |
| AT (1) | ATE499100T1 (https=) |
| AU (1) | AU2004228017C1 (https=) |
| CA (1) | CA2520613C (https=) |
| CY (1) | CY1111465T1 (https=) |
| DE (1) | DE602004031512D1 (https=) |
| DK (1) | DK1610791T3 (https=) |
| ES (1) | ES2359977T3 (https=) |
| IL (1) | IL171115A (https=) |
| MX (1) | MXPA05010450A (https=) |
| NZ (1) | NZ542548A (https=) |
| PL (1) | PL1610791T3 (https=) |
| PT (1) | PT1610791E (https=) |
| SI (1) | SI1610791T1 (https=) |
| WO (1) | WO2004089375A1 (https=) |
| ZA (1) | ZA200507877B (https=) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10053397A1 (de) * | 2000-10-20 | 2002-05-02 | Schering Ag | Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen |
| DE10043321B4 (de) * | 2000-08-24 | 2005-07-28 | Neurobiotec Gmbh | Verwendung eines transdermalen therapeutischen Systems zur Behandlung der Parkinsonschen Krankheit, zur Behandlung und Prävention des prämenstruellen Syndroms und zur Lactationshemmung |
| DE10064453A1 (de) * | 2000-12-16 | 2002-07-04 | Schering Ag | Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen |
| US20060281797A1 (en) * | 2001-12-11 | 2006-12-14 | University Of Virginia Patent Foundation | Neurorestoration with R(+) Pramipexole |
| ES2432527T3 (es) * | 2001-12-11 | 2013-12-04 | University Of Virginia Patent Foundation | Uso de pramipexol para tratar la esclerosis lateral amiotrófica |
| CA2487577C (en) | 2002-05-31 | 2014-11-18 | Titan Pharmaceuticals, Inc. | Implantable polymeric device for sustained release of buprenorphine |
| SI1610791T1 (sl) * | 2003-03-31 | 2011-05-31 | Titan Pharmaceuticals Inc | Implantibilna polimerna naprava za zadržano sproščanje dopaminskega agonista |
| MXPA05012768A (es) * | 2003-05-30 | 2006-02-22 | Titan Pharmaceuticals Inc | Dispositivo polimerico implantable para liberacion prolongada de nalmefeno. |
| PT1781264E (pt) | 2004-08-04 | 2013-10-16 | Evonik Corp | Métodos para o fabrico de dispositivis de administração e dispositivos para a mesma |
| KR20070059161A (ko) | 2004-09-21 | 2007-06-11 | 산동 루예 파마슈티칼 컴파니 리미티드 | 도파민 수용체 효능제를 함유하는 장시간 작용 서방성 제제및 그 제조방법 |
| JP2008537961A (ja) * | 2005-04-15 | 2008-10-02 | ボード、オブ、トラスティーズ、オブ、ミシガン、ステイト、ユニバーシティ | Ｇｐｃｒモジュレーター |
| WO2007022182A1 (en) * | 2005-08-15 | 2007-02-22 | University Of Virginia Patent Foundation | Neurorestoration with r(+) pramipexole |
| ES2402376T3 (es) * | 2006-04-06 | 2013-05-03 | Nupathe Inc. | Implantes para el tratamiento de estados asociados con dopamina |
| US8518926B2 (en) * | 2006-04-10 | 2013-08-27 | Knopp Neurosciences, Inc. | Compositions and methods of using (R)-pramipexole |
| WO2007121188A2 (en) * | 2006-04-10 | 2007-10-25 | Knopp Neurosciences, Inc. | Compositions and methods of using r(+) pramipexole |
| ES2379117T3 (es) | 2006-05-16 | 2012-04-20 | Knopp Neurosciences, Inc. | Composiciones de R(+) y S(-) pramipexol y métodos de utilización de las mismas |
| WO2007139744A2 (en) * | 2006-05-23 | 2007-12-06 | Titan Pharmaceuticals, Inc. | Implantable polymeric device for sustained release of buprenorphine with minimal initial burst |
| US8524695B2 (en) * | 2006-12-14 | 2013-09-03 | Knopp Neurosciences, Inc. | Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same |
| CA2681110A1 (en) * | 2007-03-14 | 2008-09-18 | Knopp Neurosciences, Inc. | Synthesis of chirally purified substituted benzothiazole diamines |
| US8124601B2 (en) * | 2007-11-21 | 2012-02-28 | Bristol-Myers Squibb Company | Compounds for the treatment of Hepatitis C |
| ES2718612T3 (es) | 2007-12-20 | 2019-07-03 | Evonik Corp | Procedimiento para preparar micropartículas que tienen un bajo volumen de disolvente residual |
| US20090247537A1 (en) * | 2008-03-25 | 2009-10-01 | William Dale Overfield | Methods for preventing or treating bruxism using dopaminergic agents |
| WO2010010136A1 (en) * | 2008-07-24 | 2010-01-28 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition comprising pramipexole and an anti-inflammatory agent for the treatment of parkinson's disease |
| KR20110071064A (ko) * | 2008-08-19 | 2011-06-28 | 크놉 뉴로사이언시스 인코포레이티드 | (ｒ)-프라미펙솔을 사용하는 조성물 및 방법 |
| US8188065B2 (en) * | 2008-10-02 | 2012-05-29 | Osteogenex Inc. | Boldine compounds for promoting bone growth |
| RU2012101792A (ru) * | 2009-06-19 | 2013-07-27 | Нопп Ньюросайенсиз, Инк. | Композиции и способы для лечения бокового амиотрофического склероза |
| US8513259B2 (en) | 2009-07-03 | 2013-08-20 | Jdp Therapeutics, Inc. | Non-sedating antihistamine injection formulations and methods of use thereof |
| US8263581B2 (en) | 2009-07-03 | 2012-09-11 | Jdp Therapeutics, Inc. | Non-sedating antihistamine injection formulations and methods of use thereof |
| WO2011012723A1 (en) | 2009-07-31 | 2011-02-03 | Ascendis Pharma As | Injectable sustained release compositions comprising a pramipexole prodrug |
| US20120191039A1 (en) | 2009-07-31 | 2012-07-26 | Ascendis Pharma A/S | Carrier linked pramipexole prodrugs |
| US20110091518A1 (en) * | 2009-09-22 | 2011-04-21 | Danielle Biggs | Implant devices having varying bioactive agent loading configurations |
| EP2496080A4 (en) * | 2009-11-02 | 2013-05-15 | Nupathe Inc | METHOD FOR THE TREATMENT OF MORBUS PARKINSON |
| KR101914119B1 (ko) | 2010-03-16 | 2018-11-02 | 타이탄 파머슈티컬즈 인코퍼레이티드 | 약물 전달용 이종 이식가능 장치 |
| US20120021770A1 (en) | 2010-07-21 | 2012-01-26 | Naqvi Shamim A | System and method for control and management of resources for consumers of information |
| US9232046B2 (en) | 2010-07-21 | 2016-01-05 | Tksn Holdings, Llc | System and method for controlling mobile services using sensor information |
| US9210528B2 (en) | 2010-07-21 | 2015-12-08 | Tksn Holdings, Llc | System and method for control and management of resources for consumers of information |
| FR2976810A1 (fr) * | 2011-06-27 | 2012-12-28 | Air Liquide | Medicament inhalable a base de neon pour traiter ou prevenir les dyskinesies |
| FR2976815A1 (fr) * | 2011-06-27 | 2012-12-28 | Air Liquide | Medicament inhalable a base d'argon pour traiter ou prevenir les dyskinesies |
| FR2976809A1 (fr) * | 2011-06-27 | 2012-12-28 | Air Liquide | Medicament inhalable a base de krypton pour traiter ou prevenir les dyskinesies |
| KR102035877B1 (ko) | 2011-11-14 | 2019-10-23 | 알파시그마 에스.피.에이. | 우울증이 있는 대상체를 위한 치료 양생법 선택을 위한 검정법 및 치료 방법 |
| WO2013096816A1 (en) | 2011-12-22 | 2013-06-27 | Biogen Idec Ma Inc. | Improved synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds |
| KR101558043B1 (ko) * | 2012-07-06 | 2015-10-07 | 에스케이케미칼주식회사 | 로티고틴 함유 경피흡수제제 |
| US9662313B2 (en) | 2013-02-28 | 2017-05-30 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
| EP3838271B1 (en) | 2013-07-12 | 2025-09-03 | Areteia Therapeutics, Inc. | Treating elevated levels of eosinophils and/or basophils |
| US9468630B2 (en) | 2013-07-12 | 2016-10-18 | Knopp Biosciences Llc | Compositions and methods for treating conditions related to increased eosinophils |
| ES2813674T3 (es) | 2013-08-13 | 2021-03-24 | Knopp Biosciences Llc | Composiciones y métodos para el tratamiento de trastornos de células plasmáticas y trastornos prolinfocíticos de células b |
| CA2921381A1 (en) | 2013-08-13 | 2015-02-19 | Knopp Biosciences Llc | Compositions and methods for treating chronic urticaria |
| EP3036923A4 (en) | 2013-08-22 | 2017-05-10 | Inc. Sensoriant | Method and system for addressing the problem of discovering relevant services and applications that are available over the internet or other communcations network |
| WO2015136446A1 (en) | 2014-03-11 | 2015-09-17 | Nestec S.A. | Methods for selecting antidepressant drug therapy to treat depression |
| US10390289B2 (en) | 2014-07-11 | 2019-08-20 | Sensoriant, Inc. | Systems and methods for mediating representations allowing control of devices located in an environment having broadcasting devices |
| US20160012453A1 (en) | 2014-07-11 | 2016-01-14 | Shamim A. Naqvi | System and Method for Inferring the Intent of a User While Receiving Signals On a Mobile Communication Device From a Broadcasting Device |
| US10824440B2 (en) | 2014-08-22 | 2020-11-03 | Sensoriant, Inc. | Deriving personalized experiences of smart environments |
| US10701165B2 (en) | 2015-09-23 | 2020-06-30 | Sensoriant, Inc. | Method and system for using device states and user preferences to create user-friendly environments |
| EP3522825B1 (en) * | 2016-10-05 | 2023-06-07 | Titan Pharmaceuticals, Inc. | Implantable devices for drug delivery with reduced burst release |
| US20180207328A1 (en) * | 2017-01-22 | 2018-07-26 | Kamalesh K. Rao | Implantable Compositions for Pain Management |
| KR20260007295A (ko) | 2018-05-24 | 2026-01-13 | 셀라니즈 이브이에이 퍼포먼스 폴리머스 엘엘씨 | 거대 분자 약물 화합물의 지속적인 방출을 위한 이식가능 장치 |
| US11689849B2 (en) | 2018-05-24 | 2023-06-27 | Nureva, Inc. | Method, apparatus and computer-readable media to manage semi-constant (persistent) sound sources in microphone pickup/focus zones |
| US11690806B2 (en) | 2018-05-24 | 2023-07-04 | Celanese Eva Performance Polymers Llc | Implantable device for sustained release of a macromolecular drug compound |
| CA3139559A1 (en) | 2019-05-09 | 2020-11-12 | Apkarian Technologies Llc | Methods and compositions for treating pain |
| JP2023522134A (ja) * | 2020-04-10 | 2023-05-26 | サイエンチュア， インコーポレイテッド | 長時間作用型アポモルフィン製剤、およびその治療送達用のインジェクター |
| BR112023022439A2 (pt) | 2021-04-26 | 2023-12-26 | Celanese Eva Performance Polymers Llc | Dispositivo implantável para liberação sustentada de um composto de fármaco macromolecular |
| CN116256439B (zh) * | 2021-12-10 | 2025-11-07 | 远大医药（中国）有限公司 | Hplc检测盐酸多巴胺注射液中焦亚硫酸钠含量的方法 |
| US12582767B2 (en) | 2021-12-30 | 2026-03-24 | Taiyo Weber | Compressible, minimally invasive implants and related systems and methods |
| CN117323305B (zh) * | 2023-11-07 | 2024-06-07 | 杭州沐源生物医药科技有限公司 | 溴隐亭片剂及其制备方法 |
| WO2025174767A1 (en) * | 2024-02-13 | 2025-08-21 | Biraj Investments, Llc | Highly loaded implantable devices with high tensile strength for drug delivery |
Family Cites Families (122)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1050353B (it) * | 1966-01-06 | 1981-03-10 | Ceskoslovenska Akademie Ved | Supporti per sostanze biologigamente attive |
| US3717639A (en) * | 1967-05-04 | 1973-02-20 | Little Inc A | Process for the preparation of 1-(2-nitro-3,4-di-lower-alkoxybenzyl)isoquinolines |
| US4069307A (en) * | 1970-10-01 | 1978-01-17 | Alza Corporation | Drug-delivery device comprising certain polymeric materials for controlled release of drug |
| US3814768A (en) * | 1971-11-26 | 1974-06-04 | Lewenstein E | 6-methylene-6-desoxy dihydro morphine and codeine derivatives and pharmaceutically acceptable salts |
| US4351337A (en) * | 1973-05-17 | 1982-09-28 | Arthur D. Little, Inc. | Biodegradable, implantable drug delivery device, and process for preparing and using the same |
| US4450150A (en) * | 1973-05-17 | 1984-05-22 | Arthur D. Little, Inc. | Biodegradable, implantable drug delivery depots, and method for preparing and using the same |
| US3923939A (en) * | 1974-06-07 | 1975-12-02 | Alza Corp | Process for improving release kinetics of a monolithic drug delivery device |
| US4148871A (en) * | 1977-10-11 | 1979-04-10 | Pitt Colin G | Sustained subdermal delivery ofdrugs using poly(ε-caprolactone) and its copolymers |
| US4464378A (en) * | 1981-04-28 | 1984-08-07 | University Of Kentucky Research Foundation | Method of administering narcotic antagonists and analgesics and novel dosage forms containing same |
| US4543256A (en) * | 1982-03-17 | 1985-09-24 | Northeastern University | (-)-10,1L Methylenedioxy-N-N-propylnoraporphine and methods employing it for inhibiting the effects of epileptic seizures and for prevention and treatment of duodenal ulcers |
| AU8533582A (en) | 1981-07-10 | 1984-01-12 | Reckitt & Colman Products Limited | Stable solutions of buprenorphine |
| DK119884A (da) | 1983-03-18 | 1984-09-19 | Lilly Co Eli | Fast, cylindrisk, subkutan implantation og dens anvendelse |
| US4622219A (en) * | 1983-06-17 | 1986-11-11 | Haynes Duncan H | Method of inducing local anesthesia using microdroplets of a general anesthetic |
| US4725442A (en) * | 1983-06-17 | 1988-02-16 | Haynes Duncan H | Microdroplets of water-insoluble drugs and injectable formulations containing same |
| US4535157A (en) * | 1983-11-01 | 1985-08-13 | Key Pharmaceuticals, Inc. | Process for making 6-desoxy-6-methylenenaloxone and 6-desoxy-6-methylenenaltrexone |
| US4818542A (en) * | 1983-11-14 | 1989-04-04 | The University Of Kentucky Research Foundation | Porous microspheres for drug delivery and methods for making same |
| EP0391893B1 (en) | 1983-11-14 | 1993-08-25 | The University of Kentucky Research Foundation | Porous microspheres for drug delivery and methods for making same |
| GB8332556D0 (en) * | 1983-12-06 | 1984-01-11 | Reckitt & Colmann Prod Ltd | Analgesic compositions |
| US4599342A (en) * | 1984-01-16 | 1986-07-08 | The Procter & Gamble Company | Pharmaceutical products providing enhanced analgesia |
| FR2559780B1 (fr) | 1984-02-21 | 1990-05-04 | Tech Cuir Centre | Systemes biocompatibles implantables a base de collagene permettant la conservation et/ou la culture cellulaires et/ou la liberation controlee de principes actifs |
| GB8430346D0 (en) * | 1984-11-30 | 1985-01-09 | Reckitt & Colmann Prod Ltd | Analgesic compositions |
| US4678809A (en) * | 1985-02-01 | 1987-07-07 | Michael Phillips | Injectable fomulations of disulfiram for the treatment of alcoholism |
| US4898733A (en) * | 1985-11-04 | 1990-02-06 | International Minerals & Chemical Corp. | Layered, compression molded device for the sustained release of a beneficial agent |
| US4692451A (en) * | 1985-12-11 | 1987-09-08 | Trustees Of Tufts College | Method for preventing stereotypic behavior in animals |
| DE3689650T2 (de) | 1985-12-17 | 1994-05-26 | United States Surgical Corp | Bioresorbierbare Polymere von hohem Molekulargewicht und Implantate davon. |
| US5316759A (en) * | 1986-03-17 | 1994-05-31 | Robert J. Schaap | Agonist-antagonist combination to reduce the use of nicotine and other drugs |
| US4962091A (en) * | 1986-05-23 | 1990-10-09 | Syntex (U.S.A.) Inc. | Controlled release of macromolecular polypeptides |
| JPS63122620A (ja) * | 1986-11-12 | 1988-05-26 | Sanraku Inc | ポリ乳酸マイクロスフエア及びその製造方法 |
| US5718921A (en) * | 1987-03-13 | 1998-02-17 | Massachusetts Institute Of Technology | Microspheres comprising polymer and drug dispersed there within |
| US4883666A (en) * | 1987-04-29 | 1989-11-28 | Massachusetts Institute Of Technology | Controlled drug delivery system for treatment of neural disorders |
| US5601835A (en) * | 1987-04-29 | 1997-02-11 | Massachusetts Institute Of Technology | Polymeric device for controlled drug delivery to the CNS |
| US5114719A (en) * | 1987-04-29 | 1992-05-19 | Sabel Bernhard A | Extended drug delivery of small, water-soluble molecules |
| US4861627A (en) * | 1987-05-01 | 1989-08-29 | Massachusetts Institute Of Technology | Preparation of multiwall polymeric microcapsules |
| US4897268A (en) * | 1987-08-03 | 1990-01-30 | Southern Research Institute | Drug delivery system and method of making the same |
| ES2054784T3 (es) * | 1987-08-08 | 1994-08-16 | Akzo Nv | Un metodo para la fabricacion de un implante. |
| US5156844A (en) * | 1987-11-17 | 1992-10-20 | Brown University Research Foundation | Neurological therapy system |
| GB8728294D0 (en) * | 1987-12-03 | 1988-01-06 | Reckitt & Colmann Prod Ltd | Treatment compositions |
| US5002935A (en) * | 1987-12-30 | 1991-03-26 | University Of Florida | Improvements in redox systems for brain-targeted drug delivery |
| US4882335A (en) * | 1988-06-13 | 1989-11-21 | Alko Limited | Method for treating alcohol-drinking response |
| US5236714A (en) * | 1988-11-01 | 1993-08-17 | Alza Corporation | Abusable substance dosage form having reduced abuse potential |
| FI916066A0 (fi) | 1989-06-21 | 1991-12-20 | Univ Brown Res Found | Neurologiskt vaordsystem. |
| US5750136A (en) * | 1989-11-03 | 1998-05-12 | Riker Laboratories, Inc. | Bioadhesive composition and patch |
| DE3939376C1 (https=) | 1989-11-29 | 1991-05-08 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg, 5450 Neuwied, De | |
| US5240711A (en) * | 1989-11-29 | 1993-08-31 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Transdermal therapeutic system comprising as active component buprenorphine |
| US5075341A (en) | 1989-12-01 | 1991-12-24 | The Mclean Hospital Corporation | Treatment for cocaine abuse |
| US5219858A (en) * | 1990-03-27 | 1993-06-15 | Parnell Pharmaceuticals, Inc. | Method and compositions for effecting withdrawal from drug dependency |
| CA2040141C (en) | 1990-04-13 | 2002-05-14 | Minoru Yamada | Biodegradable high-molecular polymers, production and use therof |
| US6517859B1 (en) | 1990-05-16 | 2003-02-11 | Southern Research Institute | Microcapsules for administration of neuroactive agents |
| US5086058A (en) * | 1990-06-04 | 1992-02-04 | Alko Ltd. | Method for treating alcoholism with nalmefene |
| US5128145A (en) * | 1990-06-13 | 1992-07-07 | Alza Corporation | Dosage form for Parkinson's disease, spasticity and muscle spasms |
| US5069909A (en) | 1990-06-20 | 1991-12-03 | Cygnus Therapeutic Systems | Transdermal administration of buprenorphine |
| US5114718A (en) * | 1990-09-20 | 1992-05-19 | The Procter & Gamble Company | Sustained release compositions for treating periodontol disease |
| US5486362A (en) * | 1991-05-07 | 1996-01-23 | Dynagen, Inc. | Controlled, sustained release delivery system for treating drug dependency |
| US5211951A (en) * | 1991-07-24 | 1993-05-18 | Merck & Co., Inc. | Process for the manufacture of bioerodible poly (orthoester)s and polyacetals |
| US5478577A (en) | 1993-11-23 | 1995-12-26 | Euroceltique, S.A. | Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level |
| US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| US5968551A (en) * | 1991-12-24 | 1999-10-19 | Purdue Pharma L.P. | Orally administrable opioid formulations having extended duration of effect |
| FR2695826B1 (fr) * | 1992-09-21 | 1995-01-06 | Theramex | Nouvelles compositions pharmaceutiques à base de dérivés de nomégestrol et leurs procédés d'obtention. |
| US5580876A (en) | 1992-09-21 | 1996-12-03 | Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University | Method of simultaneously enhancing analgesic potency and attenuating dependence liability caused by morphine and other bimodally-acting opioid agonists |
| US5604194A (en) * | 1992-11-17 | 1997-02-18 | The Procter & Gamble Company | Stable liquid detergent compositions comprising specific brightener and PVP to inhibit dye transfer |
| US5298017A (en) * | 1992-12-29 | 1994-03-29 | Alza Corporation | Layered electrotransport drug delivery system |
| DE69434304T2 (de) * | 1993-03-26 | 2005-12-29 | Merkus, Franciscus Wilhelmus H.M. | Pharmazeutische Zusammensetzungen zur intranasalen Verabreichung von Dihydroergotamin |
| GB9311132D0 (en) * | 1993-05-28 | 1993-07-14 | Eisai London Res Lab Ltd | Control of cell death |
| US5650173A (en) * | 1993-11-19 | 1997-07-22 | Alkermes Controlled Therapeutics Inc. Ii | Preparation of biodegradable microparticles containing a biologically active agent |
| CN1074923C (zh) * | 1993-11-19 | 2001-11-21 | 詹森药业有限公司 | 微囊密封的3-哌啶基取代的1,2-苯并异唑类和1,2-苯并异噻唑类 |
| CA2474701C (en) * | 1993-11-19 | 2009-01-27 | Alkermes Controlled Therapeutics Inc. Ii | Preparation of biodegradeable microparticles containing a biologically active agent |
| JP3720386B2 (ja) | 1993-12-27 | 2005-11-24 | 住友製薬株式会社 | 薬物放出制御製剤 |
| DE69529054T2 (de) * | 1994-02-28 | 2003-08-21 | Nanopharm Ag | System zur gezielten wirkstoffzufuhr, verfahren zu seiner herstellung und verwendung |
| JP3310982B2 (ja) * | 1994-04-22 | 2002-08-05 | ペンテツク・フアーマシユーテイカルズ・インコーポレイテツド | 男性の勃起機能不全を改善するための剤形及び方法 |
| JP2819236B2 (ja) * | 1994-05-06 | 1998-10-30 | 日東電工株式会社 | 経皮吸収製剤 |
| US5604198A (en) * | 1994-05-12 | 1997-02-18 | Poduslo; Joseph F. | Method to enhance permeability of the blood/brain blood/nerve barriers to therapeutic agents |
| US5633000A (en) * | 1994-06-23 | 1997-05-27 | Axxia Technologies | Subcutaneous implant |
| US5626862A (en) * | 1994-08-02 | 1997-05-06 | Massachusetts Institute Of Technology | Controlled local delivery of chemotherapeutic agents for treating solid tumors |
| US6063116A (en) * | 1994-10-26 | 2000-05-16 | Medarex, Inc. | Modulation of cell proliferation and wound healing |
| US5562917A (en) * | 1994-12-23 | 1996-10-08 | Pentech Pharmaceuticals, Inc. | Transdermal administration of apomorphine |
| WO1996024330A1 (en) * | 1995-02-10 | 1996-08-15 | Medtronic, Inc. | Method and device for administering analgesics |
| IL112834A (en) | 1995-03-01 | 2000-12-06 | Yeda Res & Dev | Pharmaceutical compositions for controlled release of soluble receptors |
| US5587381A (en) | 1995-03-27 | 1996-12-24 | Sinclair; John D. | Method for terminating methadone maintenance through extinction of the opiate-taking responses |
| US5877224A (en) * | 1995-07-28 | 1999-03-02 | Rutgers, The State University Of New Jersey | Polymeric drug formulations |
| CA2182851A1 (en) * | 1995-08-15 | 1997-02-16 | August Masaru Watanabe | Method for treating substance abuse withdrawal |
| US6004962A (en) | 1995-09-11 | 1999-12-21 | Gooberman; Lance L. | Rapid opioid detoxification |
| US5733565A (en) | 1996-02-23 | 1998-03-31 | The Population Council, Center For Biomedical Research | Male contraceptive implant |
| US6004969A (en) | 1996-04-15 | 1999-12-21 | National Science Council | Transdermal delivery of buprenorphine preparations |
| US20040024006A1 (en) * | 1996-05-06 | 2004-02-05 | Simon David Lew | Opioid pharmaceutical compositions |
| US20030211157A1 (en) * | 1996-05-06 | 2003-11-13 | Simon David Lew | Semi-sol delivery blend for water soluble molecules |
| US6271240B1 (en) * | 1996-05-06 | 2001-08-07 | David Lew Simon | Methods for improved regulation of endogenous dopamine in prolonged treatment of opioid addicted individuals |
| JPH09330237A (ja) * | 1996-06-07 | 1997-12-22 | Toshiba Corp | プロセス切り替え装置およびプロセス切り替え方法 |
| US5980948A (en) * | 1996-08-16 | 1999-11-09 | Osteotech, Inc. | Polyetherester copolymers as drug delivery matrices |
| BR9605275A (pt) | 1996-10-17 | 1998-07-21 | H2T Handheld Technology Ltda | Sistema de comunicaçao por infravermelho difuso |
| US6203813B1 (en) * | 1997-01-13 | 2001-03-20 | Lance L. Gooberman | Pharmaceutical delivery device and method of preparation therefor |
| US20010036469A1 (en) * | 1997-01-13 | 2001-11-01 | Gooberman Lance L. | Opiate antagonist implant and process for preparation therefor |
| GB9700878D0 (en) | 1997-01-17 | 1997-03-05 | Scherer Ltd R P | Dosage forms and method for ameliorating male erectile dysfunction |
| US5968547A (en) * | 1997-02-24 | 1999-10-19 | Euro-Celtique, S.A. | Method of providing sustained analgesia with buprenorphine |
| US5919473A (en) * | 1997-05-12 | 1999-07-06 | Elkhoury; George F. | Methods and devices for delivering opioid analgesics to wounds via a subdermal implant |
| US6342250B1 (en) * | 1997-09-25 | 2002-01-29 | Gel-Del Technologies, Inc. | Drug delivery devices comprising biodegradable protein for the controlled release of pharmacologically active agents and method of making the drug delivery devices |
| EP1041988A4 (en) * | 1997-12-22 | 2002-03-13 | Euro Celtique Sa | METHOD FOR PREVENTING ABUSE OF OPIOID DOSES FORMS |
| TW460599B (en) * | 1998-01-14 | 2001-10-21 | Toshiba Corp | Method for forming fine wiring pattern |
| US6007841A (en) | 1998-03-13 | 1999-12-28 | Algos Pharmaceutical Corporation | Analgesic composition and method for treating pain |
| US6613358B2 (en) * | 1998-03-18 | 2003-09-02 | Theodore W. Randolph | Sustained-release composition including amorphous polymer |
| EP0945133A1 (en) * | 1998-03-26 | 1999-09-29 | Lipha | Combination for the treatment of alcohol and drug dependence containing an opioid antagonist and a NMDA receptor complex modulator |
| US6423345B2 (en) * | 1998-04-30 | 2002-07-23 | Acusphere, Inc. | Matrices formed of polymer and hydrophobic compounds for use in drug delivery |
| US6001845A (en) * | 1998-06-19 | 1999-12-14 | Schering Corporation | Combination of phentolamine and apomorphine for the treatment of human sexual function and dysfunction |
| US6011043A (en) * | 1998-06-19 | 2000-01-04 | Schering Corporation | Combination of phentolamine and apomorphine for the treatment of human sexual function and dysfunction |
| US5994363A (en) * | 1998-08-24 | 1999-11-30 | Pentech Pharmaceuticals, Inc. | Amelioration of apomorphine adverse effects |
| WO2000019976A2 (en) | 1998-10-02 | 2000-04-13 | Guilford Pharmaceuticals Inc. | Biodegradable terephthalate polyester-poly(phosphonate) and polyester-poly(phosphite) compositions, articles, and methods of using them |
| KR100383252B1 (ko) | 1998-12-17 | 2003-07-16 | 주식회사 삼양사 | 부프레놀핀을함유하는경피투여조성물및이를포함하는패취 |
| US6541021B1 (en) * | 1999-03-18 | 2003-04-01 | Durect Corporation | Devices and methods for pain management |
| CA2371836C (en) | 1999-05-27 | 2006-01-31 | Acusphere, Inc. | Porous drug matrices and methods of manufacture thereof |
| AU783925B2 (en) * | 1999-08-10 | 2005-12-22 | Uab Research Foundation | Method of treating traumatic brain and spinal cord injuries and other neurogenic conditions using non-steroidal anti-inflammatory drugs and naturally occurring conotoxins |
| RO121631B1 (ro) | 1999-08-27 | 2008-01-30 | Southern Research Institute | Compoziţie cu buprenorfină şi utilizarea acesteia pentru reducerea consumului de heroină şi/sau alcool |
| WO2001043726A1 (en) * | 1999-12-16 | 2001-06-21 | Trident Technologies, Llc | System and method for extended delivery of a therapeutic agent with its receptor loading dose |
| JP2004528283A (ja) * | 2000-10-12 | 2004-09-16 | ファルマシア・アンド・アップジョン・カンパニー | パーキンソン病の治療方法 |
| WO2002087586A1 (en) * | 2001-04-26 | 2002-11-07 | Control Delivery Systems, Inc. | Sustained release drug delivery system containing codrugs |
| US20020198574A1 (en) | 2001-06-22 | 2002-12-26 | Ron Gumpert | Automatic sobriety training and reconditioning system |
| GB0202900D0 (en) * | 2002-02-07 | 2002-03-27 | Laxdale Ltd | Novel formulations of drugs |
| WO2003094888A1 (en) * | 2002-05-07 | 2003-11-20 | Control Delivery Systems, Inc. | Processes for forming a drug delivery device |
| CA2487577C (en) * | 2002-05-31 | 2014-11-18 | Titan Pharmaceuticals, Inc. | Implantable polymeric device for sustained release of buprenorphine |
| AU2003297073A1 (en) * | 2002-12-13 | 2004-07-09 | Euro-Celtique S.A. | Transdermal buprenorphine dosage regimen for analgesia |
| SI1610791T1 (sl) * | 2003-03-31 | 2011-05-31 | Titan Pharmaceuticals Inc | Implantibilna polimerna naprava za zadržano sproščanje dopaminskega agonista |
| MXPA05012768A (es) * | 2003-05-30 | 2006-02-22 | Titan Pharmaceuticals Inc | Dispositivo polimerico implantable para liberacion prolongada de nalmefeno. |
| US20050245541A1 (en) * | 2004-03-19 | 2005-11-03 | Elliot Ehrich | Methods for treating alcoholism |
| WO2007139744A2 (en) * | 2006-05-23 | 2007-12-06 | Titan Pharmaceuticals, Inc. | Implantable polymeric device for sustained release of buprenorphine with minimal initial burst |
-
2004
- 2004-03-31 SI SI200431641T patent/SI1610791T1/sl unknown
- 2004-03-31 WO PCT/US2004/010270 patent/WO2004089375A1/en not_active Ceased
- 2004-03-31 PT PT04758809T patent/PT1610791E/pt unknown
- 2004-03-31 US US10/815,481 patent/US20050031667A1/en not_active Abandoned
- 2004-03-31 EP EP04758809A patent/EP1610791B1/en not_active Expired - Lifetime
- 2004-03-31 JP JP2006509657A patent/JP5064794B2/ja not_active Expired - Fee Related
- 2004-03-31 MX MXPA05010450A patent/MXPA05010450A/es active IP Right Grant
- 2004-03-31 CN CN201210167123.5A patent/CN102772357B/zh not_active Expired - Lifetime
- 2004-03-31 DK DK04758809.0T patent/DK1610791T3/da active
- 2004-03-31 AU AU2004228017A patent/AU2004228017C1/en not_active Ceased
- 2004-03-31 NZ NZ542548A patent/NZ542548A/en not_active IP Right Cessation
- 2004-03-31 PL PL04758809T patent/PL1610791T3/pl unknown
- 2004-03-31 AT AT04758809T patent/ATE499100T1/de active
- 2004-03-31 DE DE602004031512T patent/DE602004031512D1/de not_active Expired - Lifetime
- 2004-03-31 KR KR1020057018582A patent/KR101152183B1/ko not_active Expired - Fee Related
- 2004-03-31 ES ES04758809T patent/ES2359977T3/es not_active Expired - Lifetime
- 2004-03-31 CA CA2520613A patent/CA2520613C/en not_active Expired - Lifetime
- 2004-03-31 CN CNA2004800110608A patent/CN1777426A/zh active Pending
- 2004-03-31 ZA ZA200507877A patent/ZA200507877B/en unknown
-
2005
- 2005-09-26 IL IL171115A patent/IL171115A/en active IP Right Grant
-
2008
- 2008-05-12 US US12/119,334 patent/US20080311171A1/en not_active Abandoned
- 2008-12-22 US US12/341,766 patent/US20090162412A1/en not_active Abandoned
-
2011
- 2011-02-04 JP JP2011023211A patent/JP5608581B2/ja not_active Expired - Fee Related
- 2011-05-17 CY CY20111100471T patent/CY1111465T1/el unknown
-
2012
- 2012-06-15 US US13/525,193 patent/US8852623B2/en not_active Expired - Lifetime
-
2013
- 2013-07-16 JP JP2013147574A patent/JP2013213056A/ja active Pending
-
2014
- 2014-10-03 US US14/506,426 patent/US9278163B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2006522149A5 (https=) | ||
| CA2520613A1 (en) | Implantable polymeric device for sustained release of dopamine agonist | |
| AU2004228017B2 (en) | Implantable polymeric device for sustained release of dopamine agonist | |
| JP2007511516A5 (https=) | ||
| HRP20050077B1 (hr) | Postupci i oblici doziranja za kontrolirano oslobađanje paliperidona | |
| US20070275031A1 (en) | Implantable polymeric device for sustained release of buprenorphine with minimal initial burst | |
| RU2006106464A (ru) | Лекарственные формы с замедленным высвобождением зипразидона | |
| RU2006143540A (ru) | Содержащие варденафил лекарственные формы с регулируемым высвобождением действующего вещества | |
| RU2006118321A (ru) | Фармацевтические композиции замедленного высвобождения, содержащие аплиндор и его производные | |
| WO2020086673A1 (en) | Ketamine oral transmucosal delivery system | |
| JP2008543936A5 (https=) | ||
| CA2676910A1 (en) | Medicament for the treatment of endometriosis | |
| RS20050835A (sr) | Sastavi bukalnih doznih oblika za produženo otpuštanje leka i postupak za njihovo dobijanje | |
| EP3687508A1 (en) | Delivery pharmaceutical compositions including permeation enhancers | |
| WO2024037536A1 (zh) | 包含伐尼克兰的缓释制剂及其制备方法 | |
| TW201735904A (zh) | 口腔內貼附劑 | |
| HK1177895B (en) | Implantable polymeric device for sustained release of dopamine agonist | |
| JP2020533295A5 (https=) | ||
| ZAN et al. | Advances in study of fluorouracil for implantation and its clinical application in adenocarcinoma | |
| TW200820996A (en) | Transdermal method and patch for emesis |