|
TWI329105B
(en)
|
2002-02-01 |
2010-08-21 |
Rigel Pharmaceuticals Inc |
2,4-pyrimidinediamine compounds and their uses
|
|
BRPI0413018B8
(pt)
|
2003-07-30 |
2021-05-25 |
Rigel Pharmaceuticals Inc |
composto, e, uso de um composto
|
|
WO2006045010A2
(en)
*
|
2004-10-20 |
2006-04-27 |
Resverlogix Corp. |
Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases
|
|
US20060121040A1
(en)
*
|
2004-12-08 |
2006-06-08 |
Wisconsin Alumni Research Foundation |
Compositions and methods for treating neuroendocrine tumors
|
|
USRE46558E1
(en)
|
2005-04-28 |
2017-09-26 |
Paloma Pharmaceuticals, Inc. |
Compositions and methods to treat diseases characterized by cellular proliferation and angiogenesis
|
|
CA2610647C
(en)
*
|
2005-05-27 |
2015-02-03 |
Brian Smith |
Novel inhibitors of pyruvate kinase as therapeutic agents for cancer
|
|
US20070203161A1
(en)
|
2006-02-24 |
2007-08-30 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
|
WO2006133426A2
(en)
|
2005-06-08 |
2006-12-14 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
|
EP1896134A2
(en)
|
2005-06-13 |
2008-03-12 |
Rigel Pharmaceuticals, Inc. |
Methods and compositions for treating degenerative bone disorders
|
|
PL1734251T3
(pl)
*
|
2005-06-17 |
2007-05-31 |
Magneti Marelli Powertrain Spa |
Wtryskiwacz paliwa
|
|
CA2617213C
(en)
|
2005-07-29 |
2014-01-28 |
Resverlogix Corp. |
Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
|
|
EP2455382B1
(en)
|
2005-12-13 |
2016-10-26 |
Incyte Holdings Corporation |
Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors
|
|
WO2007076372A2
(en)
*
|
2005-12-23 |
2007-07-05 |
University Of Rochester |
Treatment of neuroaids using inhibitors of glycogen synthase kinase (gsk)-3
|
|
CA2642229C
(en)
|
2006-02-24 |
2015-05-12 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
|
BRPI0708318A2
(pt)
*
|
2006-02-28 |
2011-05-24 |
Paloma Pharmaceuticals, Inc. |
composições e uso de compostos para tratar doenças caracterizadas por proliferação celular e angiogênese
|
|
BRPI0708615A2
(pt)
|
2006-03-07 |
2011-06-07 |
Array Biopharma Inc |
compostos de pirazol heterobicìclicos e métodos de uso
|
|
ES2369739T3
(es)
|
2006-03-20 |
2011-12-05 |
Seikagaku Corporation |
Agente terapéutico para la artritis reumatoide.
|
|
JP2009539878A
(ja)
*
|
2006-06-08 |
2009-11-19 |
アレイ バイオファーマ、インコーポレイテッド |
キノリン化合物および使用方法
|
|
EP2046119A2
(en)
*
|
2006-07-07 |
2009-04-15 |
Myriad Genetics, Inc. |
Treatment of psychiatric disorders
|
|
WO2008092231A1
(en)
|
2007-02-01 |
2008-08-07 |
Resverlogix Corp. |
Compounds for the prevention and treatment of cardiovascular diseases
|
|
EP3070090B1
(en)
|
2007-06-13 |
2018-12-12 |
Incyte Holdings Corporation |
Use of salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h- pyrazol-1-yl)-3- cyclopentylpropanenitrile
|
|
US8309566B2
(en)
|
2008-02-15 |
2012-11-13 |
Rigel Pharmaceuticals, Inc. |
Pyrimidine-2-amine compounds and their use as inhibitors of JAK kinases
|
|
TW200942544A
(en)
|
2008-03-03 |
2009-10-16 |
Takeda Pharmaceutical |
Combination drug
|
|
WO2009111644A2
(en)
*
|
2008-03-05 |
2009-09-11 |
The Regents Of The University Of Michigan |
Compositions and methods for diagnosing and treating pancreatic cancer
|
|
US20110021618A1
(en)
*
|
2008-03-25 |
2011-01-27 |
Paloma Pharmaceuticals, Inc. |
Methods of treating fibrotic disorders
|
|
MX2010011463A
(es)
|
2008-04-16 |
2011-06-03 |
Portola Pharm Inc |
2,6-diamino-pirimidin-5-il-carboxamidas como inhibidores de syk o jak quinasas.
|
|
US8138339B2
(en)
|
2008-04-16 |
2012-03-20 |
Portola Pharmaceuticals, Inc. |
Inhibitors of protein kinases
|
|
NZ588830A
(en)
|
2008-04-22 |
2012-11-30 |
Portola Pharm Inc |
Inhibitors of protein kinases
|
|
KR101629356B1
(ko)
|
2008-06-26 |
2016-06-13 |
리스버로직스 코퍼레이션 |
퀴나졸리논 유도체의 제조방법
|
|
CA2731849C
(en)
*
|
2008-07-25 |
2017-07-11 |
Emory University |
Use of 7,8-dihydroxyflavone and derivatives thereof as neuroprotectants and antidepressants
|
|
AR073231A1
(es)
*
|
2008-08-29 |
2010-10-20 |
Genentech Inc |
Metodos diagnosticos y tratamientos para los tumores independientes del vegf (factor de crecimiento endotelial vascular)
|
|
US20120046242A1
(en)
*
|
2008-12-24 |
2012-02-23 |
Massachusetts Institute Of Technology |
Molecular activators of the wnt/beta-catenin pathway
|
|
AU2010204106B2
(en)
|
2009-01-08 |
2014-05-08 |
Resverlogix Corp. |
Compounds for the prevention and treatment of cardiovascular disease
|
|
NZ595087A
(en)
|
2009-02-11 |
2013-03-28 |
Merck Patent Gmbh |
Novel amino azaheterocyclic carboxamides
|
|
NZ755378A
(en)
|
2009-03-18 |
2022-07-29 |
Resverlogix Corp |
Novel quinazolinones and related compounds for use as anti-inflammatory agents
|
|
KR20190091564A
(ko)
|
2009-04-22 |
2019-08-06 |
리스버로직스 코퍼레이션 |
신규한 소염제
|
|
SG176111A1
(en)
|
2009-05-22 |
2011-12-29 |
Incyte Corp |
3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]octane- or heptane-nitrile as jak inhibitors
|
|
JP5775070B2
(ja)
|
2009-05-22 |
2015-09-09 |
インサイト・コーポレイションＩｎｃｙｔｅ Ｃｏｒｐｏｒａｔｉｏｎ |
ヤヌスキナーゼ阻害剤としてのピラゾール−４−イル−ピロロ［２，３−ｄ］ピリミジンおよびピロール−３−イル−ピロロ［２，３−ｄ］ピリミジンのＮ−（ヘテロ）アリール−ピロリジン誘導体
|
|
CN102471338B
(zh)
|
2009-08-07 |
2014-07-02 |
默克专利有限公司 |
氮杂杂环化合物
|
|
AR078012A1
(es)
|
2009-09-01 |
2011-10-05 |
Incyte Corp |
Derivados heterociclicos de las pirazol-4-il- pirrolo (2,3-d) pirimidinas como inhibidores de la quinasa janus
|
|
CN102812014B
(zh)
*
|
2009-10-30 |
2016-01-20 |
多美恩医疗公司 |
新颖的肟衍生物及其作为代谢型谷氨酸受体的别构调节剂的用途
|
|
PT3354652T
(pt)
|
2010-03-10 |
2020-07-20 |
Incyte Holdings Corp |
Derivados de piperidin-4-ilazetidina como inibidores de jak1
|
|
RS54824B1
(sr)
|
2010-05-21 |
2016-10-31 |
Incyte Holdings Corp |
Topikalna formulacija za inhibiciju jak-a
|
|
EP2579870B1
(en)
|
2010-06-09 |
2018-02-14 |
Emory University |
Trkb agonists and methods of use
|
|
UA110113C2
(xx)
|
2010-07-29 |
2015-11-25 |
|
Біциклічні азагетероциклічні карбоксаміди
|
|
US9586938B2
(en)
|
2010-07-29 |
2017-03-07 |
Merck Patent Gmbh |
Cyclic amine azaheterocyclic carboxamides
|
|
US9102625B2
(en)
|
2010-11-01 |
2015-08-11 |
Portola Pharmaceuticals, Inc. |
Nicotinamides as JAK kinase modulators
|
|
US9198911B2
(en)
|
2010-11-02 |
2015-12-01 |
The Trustees Of Columbia University In The City Of New York |
Methods for treating hair loss disorders
|
|
WO2012068440A1
(en)
|
2010-11-19 |
2012-05-24 |
Incyte Corporation |
Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as jak inhibitors
|
|
CA2818542A1
(en)
|
2010-11-19 |
2012-05-24 |
Incyte Corporation |
Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as jak inhibitors
|
|
PT2643313T
(pt)
|
2010-11-24 |
2016-10-11 |
Merck Patent Gmbh |
Quinazolina carboxamida azetidinas
|
|
WO2012112791A1
(en)
|
2011-02-16 |
2012-08-23 |
Paloma Pharmaceuticals, Inc. |
Radiation countermeasure agents
|
|
US9493436B2
(en)
|
2011-04-26 |
2016-11-15 |
Indiana University Research And Technology Corporation |
Tyrosine phosphatase inhibitors and uses thereof to modulate the activity of enzymes involved in the pathology of Mycobacterium tuberculosis
|
|
MY165963A
(en)
|
2011-06-20 |
2018-05-18 |
Incyte Holdings Corp |
Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as jak inhibitors
|
|
TW201313721A
(zh)
|
2011-08-18 |
2013-04-01 |
Incyte Corp |
作為ｊａｋ抑制劑之環己基氮雜環丁烷衍生物
|
|
UA111854C2
(uk)
|
2011-09-07 |
2016-06-24 |
Інсайт Холдінгс Корпорейшн |
Способи і проміжні сполуки для отримання інгібіторів jak
|
|
MX346095B
(es)
|
2011-09-12 |
2017-03-07 |
Merck Patent Gmbh |
Nuevas imidazol-aminas como moduladores de la actividad de cinasas.
|
|
CN103930407B
(zh)
|
2011-09-12 |
2019-02-26 |
默克专利有限公司 |
用作激酶活性调节剂的氨基嘧啶衍生物
|
|
RU2640115C2
(ru)
|
2011-11-01 |
2017-12-26 |
Ресверлоджикс Корп. |
Фармацевтические композиции замещенных хиназолинонов
|
|
CA3094793A1
(en)
|
2011-11-23 |
2013-05-30 |
Portola Pharmaceuticals, Inc. |
Pyrazine kinase inhibitors
|
|
SG11201402387WA
(en)
|
2011-12-22 |
2014-09-26 |
Merck Patent Gmbh |
Novel heterocyclic carboxamides as modulators of kinase activity
|
|
CN104582705A
(zh)
*
|
2012-01-10 |
2015-04-29 |
林伯士艾瑞斯公司 |
白介素-1受体相关激酶(irak)抑制剂和其用途
|
|
WO2013152252A1
(en)
|
2012-04-06 |
2013-10-10 |
OSI Pharmaceuticals, LLC |
Combination anti-cancer therapy
|
|
TW201406761A
(zh)
|
2012-05-18 |
2014-02-16 |
Incyte Corp |
做爲ｊａｋ抑制劑之哌啶基環丁基取代之吡咯并吡啶及吡咯并嘧啶衍生物
|
|
EP2877461B1
(en)
|
2012-07-27 |
2018-05-09 |
Emory University |
Heterocyclic flavone derivatives, compositions, and methods related thereto
|
|
US9676756B2
(en)
|
2012-10-08 |
2017-06-13 |
Portola Pharmaceuticals, Inc. |
Substituted pyrimidinyl kinase inhibitors
|
|
CN113384546A
(zh)
|
2012-11-15 |
2021-09-14 |
因赛特公司 |
鲁索利替尼的缓释剂型
|
|
CA2890288A1
(en)
|
2012-11-16 |
2014-05-22 |
Merck Patent Gmbh |
Novel heterocyclic derivatives as modulators of kinase activity
|
|
AR093511A1
(es)
|
2012-11-16 |
2015-06-10 |
Merck Patent Gmbh |
Derivados de imidazol-piperidinilo como moduladores de la actividad de cinasas
|
|
US9073878B2
(en)
|
2012-11-21 |
2015-07-07 |
Zenith Epigenetics Corp. |
Cyclic amines as bromodomain inhibitors
|
|
US9765039B2
(en)
|
2012-11-21 |
2017-09-19 |
Zenith Epigenetics Ltd. |
Biaryl derivatives as bromodomain inhibitors
|
|
SG10201800741QA
(en)
|
2012-11-29 |
2018-03-28 |
Merck Patent Gmbh |
BENZO-[d][1,2,3]TRIAZINE COMPOUNDS AND USE AS p70S6K INHIBITORS
|
|
AU2013365926B9
(en)
|
2012-12-21 |
2019-01-17 |
Zenith Epigenetics Ltd. |
Novel heterocyclic compounds as bromodomain inhibitors
|
|
WO2014138168A1
(en)
|
2013-03-06 |
2014-09-12 |
Incyte Corporation |
Processes and intermediates for making a jak inhibitor
|
|
SG11201505999VA
(en)
|
2013-03-11 |
2015-08-28 |
Merck Patent Gmbh |
6-[4-(1 h-imidazol-2-yl)piperidin-1 -yl]pyrimidin-4-amine derivatives as modulators of kinase activity
|
|
SG10201801069QA
(en)
|
2013-08-07 |
2018-03-28 |
Incyte Corp |
Sustained release dosage forms for a jak1 inhibitor
|
|
EP3122900A1
(en)
|
2014-03-24 |
2017-02-01 |
F. Hoffmann-La Roche AG |
Cancer treatment with c-met antagonists and correlation of the latter with hgf expression
|
|
CA2944573C
(en)
|
2014-04-03 |
2022-10-25 |
Merck Patent Gmbh |
Combinations of cancer therapeutics
|
|
US9498467B2
(en)
|
2014-05-30 |
2016-11-22 |
Incyte Corporation |
Treatment of chronic neutrophilic leukemia (CNL) and atypical chronic myeloid leukemia (aCML) by inhibitors of JAK1
|
|
LT3186257T
(lt)
|
2014-08-27 |
2019-04-25 |
Prexton Therapeutics Sa |
Nauji chromono oksimo dariniai ir jų panaudojimas kaip metabotropinių gliutamato receptorių alosterinių moduliatorių
|
|
JO3789B1
(ar)
|
2015-03-13 |
2021-01-31 |
Resverlogix Corp |
التراكيب والوسائل العلاجية المعتمدة لمعالجة الامراض المتعلقة بالمتممة
|
|
RU2018110580A
(ru)
|
2015-08-27 |
2019-09-30 |
Прекстон Терапьютикс Са |
Проникающее в мозг производное оксима хромона для терапии леводопа-индуцированной дискинезии
|
|
GB201516905D0
(en)
*
|
2015-09-24 |
2015-11-11 |
Stratified Medical Ltd |
Treatment of Neurodegenerative diseases
|
|
EP3260445A1
(en)
*
|
2016-06-24 |
2017-12-27 |
Universität Konstanz |
Compounds for use as an anti-bacterial or anti-fungal agent and as a zinc sensor
|
|
US10759865B2
(en)
|
2017-08-22 |
2020-09-01 |
Eyal Levit |
Treatment of diabetes mellitus
|
|
AR113922A1
(es)
|
2017-12-08 |
2020-07-01 |
Incyte Corp |
Terapia de combinación de dosis baja para el tratamiento de neoplasias mieloproliferativas
|
|
EP3502095A1
(en)
|
2017-12-22 |
2019-06-26 |
Universität Konstanz |
Compound for use against pathogenic neisseria and haemophilus species and moraxella catarrhalis
|
|
EA202091830A1
(ru)
|
2018-01-30 |
2020-12-29 |
Инсайт Корпорейшн |
Способы и промежуточные соединения для получения ингибитора jak
|
|
MD3773593T2
(ro)
|
2018-03-30 |
2024-10-31 |
Incyte Corp |
Tratament hidradenitei supurative utilizând inhibitori ai JAK
|
|
US11833155B2
(en)
|
2020-06-03 |
2023-12-05 |
Incyte Corporation |
Combination therapy for treatment of myeloproliferative neoplasms
|
|
WO2022101459A1
(en)
|
2020-11-16 |
2022-05-19 |
Merck Patent Gmbh |
Kinase inhibitor combinations for cancer treatment
|