JP2006519189A - 白内障および緑内障を診断および治療するための、sgk遺伝子ファミリーの使用 - Google Patents

白内障および緑内障を診断および治療するための、sgk遺伝子ファミリーの使用 Download PDF

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JP2006519189A
JP2006519189A JP2006501737A JP2006501737A JP2006519189A JP 2006519189 A JP2006519189 A JP 2006519189A JP 2006501737 A JP2006501737 A JP 2006501737A JP 2006501737 A JP2006501737 A JP 2006501737A JP 2006519189 A JP2006519189 A JP 2006519189A
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hsgk1
hsgk3
gene
glaucoma
cataract
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JP2006519189A5 (enExample
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フローリアン・ラング
アンドレーアス・ブスヤーン
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フローリアーン・ラング
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    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/00Medicinal preparations containing peptides
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    • AHUMAN NECESSITIES
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    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4355Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/711Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
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    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P27/02Ophthalmic agents
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    • AHUMAN NECESSITIES
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/16Ophthalmology
    • G01N2800/166Cataract
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/16Ophthalmology
    • G01N2800/168Glaucoma

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  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
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  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2006501737A 2003-02-07 2004-02-05 白内障および緑内障を診断および治療するための、sgk遺伝子ファミリーの使用 Pending JP2006519189A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10305212A DE10305212A1 (de) 2003-02-07 2003-02-07 Verwendung der sgk-Genfamilie zur Diagnose und zur Therapie von Katarakt und Glaukom
PCT/EP2004/001048 WO2004069258A2 (de) 2003-02-07 2004-02-05 Verwendung der sgk-genfamilie zur diagnose und zur therapie von katarakt und glaukom

Publications (2)

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JP2006519189A true JP2006519189A (ja) 2006-08-24
JP2006519189A5 JP2006519189A5 (enExample) 2007-03-08

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JP2006501737A Pending JP2006519189A (ja) 2003-02-07 2004-02-05 白内障および緑内障を診断および治療するための、sgk遺伝子ファミリーの使用

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EP (1) EP1663246A2 (enExample)
JP (1) JP2006519189A (enExample)
KR (1) KR20050114214A (enExample)
CN (1) CN1771039A (enExample)
AU (1) AU2004210416A1 (enExample)
BR (1) BRPI0407300A (enExample)
CA (1) CA2514703A1 (enExample)
DE (1) DE10305212A1 (enExample)
MX (1) MXPA05008394A (enExample)
PL (1) PL378399A1 (enExample)
RU (1) RU2005127808A (enExample)
WO (1) WO2004069258A2 (enExample)
ZA (1) ZA200506280B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007527875A (ja) * 2004-03-11 2007-10-04 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング 線維症を抑制するための方法
JP2007529423A (ja) * 2004-03-11 2007-10-25 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング 血清・グルココルチコイド誘導性キナーゼのモジュレータの使用を含む、神経精神疾患を治療するためのグルタミン酸受容体の調節方法
JP2014506460A (ja) * 2011-01-25 2014-03-17 モネル ケミカル センシズ センター 甘味を提供若しくは調整するための組成物および方法ならびにそれらのスクリーニング方法

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004059781A1 (de) * 2004-12-10 2006-06-22 Sanofi-Aventis Deutschland Gmbh Verwendung der Serum-/Glucocorticoid regulierten Kinase
WO2007002670A2 (en) * 2005-06-28 2007-01-04 Bausch & Lomb Incorporated Method of lowering intraocular pressure
JPWO2007037560A1 (ja) * 2005-09-30 2009-04-16 リンク・ジェノミクス株式会社 Sgk2遺伝子の治療的又は診断的用途
JP5249774B2 (ja) * 2005-11-22 2013-07-31 マギル ユニバーシティ 眼内圧調節初期遺伝子およびその使用
WO2008079980A1 (en) * 2006-12-22 2008-07-03 Alcon Research, Ltd. Inhibitors of protein kinase c-delta for the treatment of glaucoma
DE102008029072A1 (de) * 2008-06-10 2009-12-17 Lang, Florian, Prof. Dr.med. Sgk3 als therapeutisches und diagnostisches Target für Alterserkrankungen
KR102357260B1 (ko) * 2020-12-10 2022-02-08 주식회사 레피겐엠디 마이크로rna를 이용한 당뇨병성 신경병증의 예측 및 진단 방법 및 이를 위한 키트
CN119303113A (zh) * 2024-09-03 2025-01-14 河北大学附属医院 Nedd4l基因在制备治疗血管内皮细胞增生性相关疾病药物中的应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996006863A1 (en) * 1994-08-30 1996-03-07 University Of Dundee Agents for inducing apoptosis and applications of said agents in therapy
AU6263996A (en) * 1995-06-07 1996-12-30 Ligand Pharmaceuticals Incorporated Method for screening for receptor agonists and antagonists
US5925523A (en) * 1996-08-23 1999-07-20 President & Fellows Of Harvard College Intraction trap assay, reagents and uses thereof
DE19708173A1 (de) * 1997-02-28 1998-09-03 Dade Behring Marburg Gmbh Zellvolumenregulierte humane Kinase h-sgk
WO1999059559A1 (en) * 1998-05-15 1999-11-25 Joslin Diabetes Center Independent regulation of basal and insulin-stimulated glucose transport
DE69937159T2 (de) * 1998-12-14 2008-06-26 University Of Dundee, Dundee Verfahren zur Aktivierung von SGK durch Phosphorylierung.
US6399655B1 (en) * 1998-12-22 2002-06-04 Johns Hopkins University, School Of Medicine Method for the prophylactic treatment of cataracts
DE19917990A1 (de) * 1999-04-20 2000-11-02 Florian Lang Arzneimittel enthaltend Hemmstoffe der zellvolumenregulierten humanen Kinase h-sgk
WO2001004145A2 (en) * 1999-07-14 2001-01-18 University Of Lausanne Glutx polypeptide family and nucleic acids encoding same
US6416759B1 (en) * 1999-09-30 2002-07-09 The Regents Of The University Of California Antiproliferative Sgk reagents and methods
US20030236246A1 (en) * 2002-04-30 2003-12-25 Brazzell Romulus Kimbro Method for decreasing capillary permeability in the retina
DE10225844A1 (de) * 2002-06-04 2003-12-18 Lang Florian sgk und nedd als diagnostische und therapeutische targets

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007527875A (ja) * 2004-03-11 2007-10-04 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング 線維症を抑制するための方法
JP2007529423A (ja) * 2004-03-11 2007-10-25 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング 血清・グルココルチコイド誘導性キナーゼのモジュレータの使用を含む、神経精神疾患を治療するためのグルタミン酸受容体の調節方法
JP2014506460A (ja) * 2011-01-25 2014-03-17 モネル ケミカル センシズ センター 甘味を提供若しくは調整するための組成物および方法ならびにそれらのスクリーニング方法
JP2016136974A (ja) * 2011-01-25 2016-08-04 モネル ケミカル センシズ センターMonell Chemical Senses Center 甘味を提供若しくは調整するための組成物および方法ならびにそれらのスクリーニング方法

Also Published As

Publication number Publication date
CN1771039A (zh) 2006-05-10
BRPI0407300A (pt) 2006-02-07
AU2004210416A1 (en) 2004-08-19
PL378399A1 (pl) 2006-04-03
RU2005127808A (ru) 2006-05-27
EP1663246A2 (de) 2006-06-07
CA2514703A1 (en) 2004-08-19
DE10305212A1 (de) 2004-08-19
WO2004069258A2 (de) 2004-08-19
KR20050114214A (ko) 2005-12-05
MXPA05008394A (es) 2005-10-05
WO2004069258A3 (de) 2005-02-24
ZA200506280B (en) 2006-05-31

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