DE10305212A1 - Verwendung der sgk-Genfamilie zur Diagnose und zur Therapie von Katarakt und Glaukom - Google Patents
Verwendung der sgk-Genfamilie zur Diagnose und zur Therapie von Katarakt und Glaukom Download PDFInfo
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- DE10305212A1 DE10305212A1 DE10305212A DE10305212A DE10305212A1 DE 10305212 A1 DE10305212 A1 DE 10305212A1 DE 10305212 A DE10305212 A DE 10305212A DE 10305212 A DE10305212 A DE 10305212A DE 10305212 A1 DE10305212 A1 DE 10305212A1
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4355—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having oxygen as a ring hetero atom
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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- A61K31/00—Medicinal preparations containing organic active ingredients
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/16—Ophthalmology
- G01N2800/166—Cataract
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/16—Ophthalmology
- G01N2800/168—Glaucoma
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Pathology (AREA)
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- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Neurosurgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Priority Applications (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10305212A DE10305212A1 (de) | 2003-02-07 | 2003-02-07 | Verwendung der sgk-Genfamilie zur Diagnose und zur Therapie von Katarakt und Glaukom |
| MXPA05008394A MXPA05008394A (es) | 2003-02-07 | 2004-02-05 | Uso de la familia de genes sgk para el diagnostico y terapia de cataratas y glaucoma. |
| PCT/EP2004/001048 WO2004069258A2 (de) | 2003-02-07 | 2004-02-05 | Verwendung der sgk-genfamilie zur diagnose und zur therapie von katarakt und glaukom |
| EP04708350A EP1663246A2 (de) | 2003-02-07 | 2004-02-05 | Verwendung der sgk-genfamilie zur diagnose und zur therapie von katarakt und glaukom |
| BR0407300-2A BRPI0407300A (pt) | 2003-02-07 | 2004-02-05 | Usos de um inibidor funcional da proteìna hsgk1 ou da proteìna hsgk3 ou de um regulador negativo da transcrição do gene hsgk1 ou do gene hsgk3, de um ácido nucleico de filamento único ou filamento duplo e de um anticorpo, fármaco, kit para diagnóstico, e, método de triagem para identificar e caracterizar substâncias terapeuticamente ativas |
| JP2006501737A JP2006519189A (ja) | 2003-02-07 | 2004-02-05 | 白内障および緑内障を診断および治療するための、ｓｇｋ遺伝子ファミリーの使用 |
| RU2005127808/15A RU2005127808A (ru) | 2003-02-07 | 2004-02-05 | Применение генов семейства sgk для диагностики и терапии катаракты и глаукомы |
| CA002514703A CA2514703A1 (en) | 2003-02-07 | 2004-02-05 | Use of the sgk gene family for diagnosis and therapy of cataracts and glaucoma |
| CNA2004800070348A CN1771039A (zh) | 2003-02-07 | 2004-02-05 | sgk基因家族用于诊断和治疗白内障和青光眼的用途 |
| KR1020057014582A KR20050114214A (ko) | 2003-02-07 | 2004-02-05 | 백내장 및 녹내장을 진단 및 치료하기 위한 ｓｇｋ 유전자패밀리의 용도 |
| PL378399A PL378399A1 (pl) | 2003-02-07 | 2004-02-05 | Zastosowanie genów z rodziny sgk do diagnozowania i terapii zaćmy i jaskry |
| AU2004210416A AU2004210416A1 (en) | 2003-02-07 | 2004-02-05 | Use of the sgk gene family for diagnosis and therapy of cataracts and glaucoma |
| ZA200506280A ZA200506280B (en) | 2003-02-07 | 2005-08-05 | Use of the sgk gene family for diagnosis and therapy of cataracts and glaucoma |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10305212A DE10305212A1 (de) | 2003-02-07 | 2003-02-07 | Verwendung der sgk-Genfamilie zur Diagnose und zur Therapie von Katarakt und Glaukom |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE10305212A1 true DE10305212A1 (de) | 2004-08-19 |
Family
ID=32730900
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE10305212A Withdrawn DE10305212A1 (de) | 2003-02-07 | 2003-02-07 | Verwendung der sgk-Genfamilie zur Diagnose und zur Therapie von Katarakt und Glaukom |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1663246A2 (enExample) |
| JP (1) | JP2006519189A (enExample) |
| KR (1) | KR20050114214A (enExample) |
| CN (1) | CN1771039A (enExample) |
| AU (1) | AU2004210416A1 (enExample) |
| BR (1) | BRPI0407300A (enExample) |
| CA (1) | CA2514703A1 (enExample) |
| DE (1) | DE10305212A1 (enExample) |
| MX (1) | MXPA05008394A (enExample) |
| PL (1) | PL378399A1 (enExample) |
| RU (1) | RU2005127808A (enExample) |
| WO (1) | WO2004069258A2 (enExample) |
| ZA (1) | ZA200506280B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102008029072A1 (de) * | 2008-06-10 | 2009-12-17 | Lang, Florian, Prof. Dr.med. | Sgk3 als therapeutisches und diagnostisches Target für Alterserkrankungen |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1964705A (zh) * | 2004-03-11 | 2007-05-16 | 默克专利有限公司 | 干扰纤维化的方法 |
| RU2006135654A (ru) * | 2004-03-11 | 2008-09-10 | Мерк Патент ГмбХ (DE) | Способы модуляции глутаматных рецепторов для лечения нейропсихиатрических расстройств, включающие применение модуляторов сывороточных и индуцируемых глюкокортикоидами киназ |
| DE102004059781A1 (de) * | 2004-12-10 | 2006-06-22 | Sanofi-Aventis Deutschland Gmbh | Verwendung der Serum-/Glucocorticoid regulierten Kinase |
| WO2007002670A2 (en) * | 2005-06-28 | 2007-01-04 | Bausch & Lomb Incorporated | Method of lowering intraocular pressure |
| JPWO2007037560A1 (ja) * | 2005-09-30 | 2009-04-16 | リンク・ジェノミクス株式会社 | Ｓｇｋ２遺伝子の治療的又は診断的用途 |
| JP5249774B2 (ja) * | 2005-11-22 | 2013-07-31 | マギル ユニバーシティ | 眼内圧調節初期遺伝子およびその使用 |
| WO2008079980A1 (en) * | 2006-12-22 | 2008-07-03 | Alcon Research, Ltd. | Inhibitors of protein kinase c-delta for the treatment of glaucoma |
| BR112013018374A2 (pt) * | 2011-01-25 | 2016-10-11 | Monell Chemical Senses Centre | composições e métodos para fornecer ou modular o sabor doce e métodos para rastrear os mesmos |
| KR102357260B1 (ko) * | 2020-12-10 | 2022-02-08 | 주식회사 레피겐엠디 | 마이크로rna를 이용한 당뇨병성 신경병증의 예측 및 진단 방법 및 이를 위한 키트 |
| CN119303113A (zh) * | 2024-09-03 | 2025-01-14 | 河北大学附属医院 | Nedd4l基因在制备治疗血管内皮细胞增生性相关疾病药物中的应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996006863A1 (en) * | 1994-08-30 | 1996-03-07 | University Of Dundee | Agents for inducing apoptosis and applications of said agents in therapy |
| AU6263996A (en) * | 1995-06-07 | 1996-12-30 | Ligand Pharmaceuticals Incorporated | Method for screening for receptor agonists and antagonists |
| US5925523A (en) * | 1996-08-23 | 1999-07-20 | President & Fellows Of Harvard College | Intraction trap assay, reagents and uses thereof |
| DE19708173A1 (de) * | 1997-02-28 | 1998-09-03 | Dade Behring Marburg Gmbh | Zellvolumenregulierte humane Kinase h-sgk |
| WO1999059559A1 (en) * | 1998-05-15 | 1999-11-25 | Joslin Diabetes Center | Independent regulation of basal and insulin-stimulated glucose transport |
| DE69937159T2 (de) * | 1998-12-14 | 2008-06-26 | University Of Dundee, Dundee | Verfahren zur Aktivierung von SGK durch Phosphorylierung. |
| US6399655B1 (en) * | 1998-12-22 | 2002-06-04 | Johns Hopkins University, School Of Medicine | Method for the prophylactic treatment of cataracts |
| DE19917990A1 (de) * | 1999-04-20 | 2000-11-02 | Florian Lang | Arzneimittel enthaltend Hemmstoffe der zellvolumenregulierten humanen Kinase h-sgk |
| WO2001004145A2 (en) * | 1999-07-14 | 2001-01-18 | University Of Lausanne | Glutx polypeptide family and nucleic acids encoding same |
| US6416759B1 (en) * | 1999-09-30 | 2002-07-09 | The Regents Of The University Of California | Antiproliferative Sgk reagents and methods |
| US20030236246A1 (en) * | 2002-04-30 | 2003-12-25 | Brazzell Romulus Kimbro | Method for decreasing capillary permeability in the retina |
| DE10225844A1 (de) * | 2002-06-04 | 2003-12-18 | Lang Florian | sgk und nedd als diagnostische und therapeutische targets |
-
2003
- 2003-02-07 DE DE10305212A patent/DE10305212A1/de not_active Withdrawn
-
2004
- 2004-02-05 AU AU2004210416A patent/AU2004210416A1/en not_active Abandoned
- 2004-02-05 WO PCT/EP2004/001048 patent/WO2004069258A2/de not_active Ceased
- 2004-02-05 PL PL378399A patent/PL378399A1/pl not_active Application Discontinuation
- 2004-02-05 CN CNA2004800070348A patent/CN1771039A/zh active Pending
- 2004-02-05 MX MXPA05008394A patent/MXPA05008394A/es unknown
- 2004-02-05 KR KR1020057014582A patent/KR20050114214A/ko not_active Withdrawn
- 2004-02-05 EP EP04708350A patent/EP1663246A2/de not_active Withdrawn
- 2004-02-05 JP JP2006501737A patent/JP2006519189A/ja active Pending
- 2004-02-05 BR BR0407300-2A patent/BRPI0407300A/pt not_active IP Right Cessation
- 2004-02-05 RU RU2005127808/15A patent/RU2005127808A/ru not_active Application Discontinuation
- 2004-02-05 CA CA002514703A patent/CA2514703A1/en not_active Abandoned
-
2005
- 2005-08-05 ZA ZA200506280A patent/ZA200506280B/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102008029072A1 (de) * | 2008-06-10 | 2009-12-17 | Lang, Florian, Prof. Dr.med. | Sgk3 als therapeutisches und diagnostisches Target für Alterserkrankungen |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1771039A (zh) | 2006-05-10 |
| BRPI0407300A (pt) | 2006-02-07 |
| AU2004210416A1 (en) | 2004-08-19 |
| PL378399A1 (pl) | 2006-04-03 |
| RU2005127808A (ru) | 2006-05-27 |
| EP1663246A2 (de) | 2006-06-07 |
| CA2514703A1 (en) | 2004-08-19 |
| JP2006519189A (ja) | 2006-08-24 |
| WO2004069258A2 (de) | 2004-08-19 |
| KR20050114214A (ko) | 2005-12-05 |
| MXPA05008394A (es) | 2005-10-05 |
| WO2004069258A3 (de) | 2005-02-24 |
| ZA200506280B (en) | 2006-05-31 |
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