JP2006514071A - 新規抗けいれん薬誘導体の塩 - Google Patents

新規抗けいれん薬誘導体の塩 Download PDF

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Publication number
JP2006514071A
JP2006514071A JP2004566659A JP2004566659A JP2006514071A JP 2006514071 A JP2006514071 A JP 2006514071A JP 2004566659 A JP2004566659 A JP 2004566659A JP 2004566659 A JP2004566659 A JP 2004566659A JP 2006514071 A JP2006514071 A JP 2006514071A
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JP
Japan
Prior art keywords
formula
salt
compound
topiramate
alkali metal
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JP2004566659A
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English (en)
Japanese (ja)
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JP2006514071A5 (https=
Inventor
アブデル−マジド，アーメド
マリアノフ，シンシア
Original Assignee
オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド
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Publication of JP2006514071A publication Critical patent/JP2006514071A/ja
Publication of JP2006514071A5 publication Critical patent/JP2006514071A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
JP2004566659A 2003-01-03 2003-12-30 新規抗けいれん薬誘導体の塩 Pending JP2006514071A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/336,435 US7041650B2 (en) 2001-07-09 2003-01-03 Anticonvulsant derivative salts
PCT/US2003/041732 WO2004063210A1 (en) 2003-01-03 2003-12-30 Novel anticonvulsant derivative salts

Publications (2)

Publication Number Publication Date
JP2006514071A true JP2006514071A (ja) 2006-04-27
JP2006514071A5 JP2006514071A5 (https=) 2006-07-13

Family

ID=32710935

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004566659A Pending JP2006514071A (ja) 2003-01-03 2003-12-30 新規抗けいれん薬誘導体の塩

Country Status (17)

Country Link
US (1) US7041650B2 (https=)
EP (1) EP1581545A1 (https=)
JP (1) JP2006514071A (https=)
KR (1) KR20050092035A (https=)
CN (1) CN100528888C (https=)
AU (1) AU2003300149A1 (https=)
CA (1) CA2511682A1 (https=)
HR (1) HRP20050603A2 (https=)
IL (1) IL169505A0 (https=)
MX (1) MXPA05007253A (https=)
NO (1) NO20053673L (https=)
NZ (1) NZ540696A (https=)
PL (1) PL377766A1 (https=)
RU (1) RU2330041C2 (https=)
UA (1) UA82214C2 (https=)
WO (1) WO2004063210A1 (https=)
ZA (1) ZA200506167B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA78211C2 (en) * 2001-07-09 2007-03-15 Ortho Mcneil Pharm Inc Salts of fructopyranose derivatives as anticonvulsant
US8779175B2 (en) * 2004-10-25 2014-07-15 Synthonics, Inc. Coordination complexes, pharmaceutical solutions comprising coordination complexes, and methods of treating patients
US20060233892A1 (en) * 2005-04-19 2006-10-19 Curt Hendrix Topiramate compositions for treatment of headache
US20090076128A1 (en) * 2007-09-15 2009-03-19 Protia Llc Deuterium-enriched topiramate
US8652527B1 (en) 2013-03-13 2014-02-18 Upsher-Smith Laboratories, Inc Extended-release topiramate capsules
US9101545B2 (en) 2013-03-15 2015-08-11 Upsher-Smith Laboratories, Inc. Extended-release topiramate capsules

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56108787A (en) * 1980-01-31 1981-08-28 Sato Yakugaku Kenkyusho:Kk Camptothecin coline salt and its preparation
JPS60109558A (ja) * 1983-09-26 1985-06-15 マクニ−ラブ・インコ−ポレ−テツド スルフアメ−トおよび医薬としてのその用途
JPS63165381A (ja) * 1986-12-19 1988-07-08 イー・アール・スクイブ・アンド・サンズ・インコーポレイテッド ［３ｓ（ｚ）］−２−［［［１−（２−アミノ−４−チアゾリル）−２−［［２，２−ジメチル−４−オキソ−１−（スルホオキシ）−３−アゼチジニル］アミノ］−２−オキソエチリデン］アミノ］オキシ］酢酸の結晶塩
JPH04221371A (ja) * 1990-03-27 1992-08-11 Warner Lambert Co 抗炎症剤としての２−置換チアゾリジノン、オキサゾリジノンおよびイミダゾリジノンの３，５−ジ−第３ブチル−４−ヒドロキシフェニルメチレン誘導体
JPH05230011A (ja) * 1991-09-19 1993-09-07 Mcneilab Inc ２，３：４，５−ビス−Ｏ−（１−メチルエチリデン）−β−Ｄ−フルクトピラノースおよび（１−メチルシクロヘキシル）メタノールのクロロサルフエートおよびスルフアメート誘導体の製法
JP2002537326A (ja) * 1999-02-24 2002-11-05 ユニヴァーシティ・オブ・シンシナティ 衝動調節障害の治療のためのスルファメート誘導体の使用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5242942A (en) * 1992-04-28 1993-09-07 Mcneilab, Inc. Anticonvulsant fructopyranose cyclic sulfites and sulfates
US5384327A (en) 1992-12-22 1995-01-24 Mcneilab, Inc. Anticonvulsant sorbopyranose sulfamates
US5498629A (en) * 1993-12-23 1996-03-12 Ortho Pharmaceutical Corporation Anticonvulsant pseudofructopyranose sulfamates
US5998380A (en) * 1995-10-13 1999-12-07 New England Medical Center Hospitals, Inc. Treatment of migraine
US5753693A (en) * 1996-06-28 1998-05-19 Ortho Pharmaceutical Corporation Anticonvulsant derivatives useful in treating manic-depressive bipolar disorder
US6541520B1 (en) 1998-08-05 2003-04-01 Brookhaven Science Associates Treatment of addiction and addiction-related behavior
UA78211C2 (en) 2001-07-09 2007-03-15 Ortho Mcneil Pharm Inc Salts of fructopyranose derivatives as anticonvulsant
US6559293B1 (en) 2002-02-15 2003-05-06 Transform Pharmaceuticals, Inc. Topiramate sodium trihydrate

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56108787A (en) * 1980-01-31 1981-08-28 Sato Yakugaku Kenkyusho:Kk Camptothecin coline salt and its preparation
JPS60109558A (ja) * 1983-09-26 1985-06-15 マクニ−ラブ・インコ−ポレ−テツド スルフアメ−トおよび医薬としてのその用途
JPS63165381A (ja) * 1986-12-19 1988-07-08 イー・アール・スクイブ・アンド・サンズ・インコーポレイテッド ［３ｓ（ｚ）］−２−［［［１−（２−アミノ−４−チアゾリル）−２−［［２，２−ジメチル−４−オキソ−１−（スルホオキシ）−３−アゼチジニル］アミノ］−２−オキソエチリデン］アミノ］オキシ］酢酸の結晶塩
JPH04221371A (ja) * 1990-03-27 1992-08-11 Warner Lambert Co 抗炎症剤としての２−置換チアゾリジノン、オキサゾリジノンおよびイミダゾリジノンの３，５−ジ−第３ブチル−４−ヒドロキシフェニルメチレン誘導体
JPH05230011A (ja) * 1991-09-19 1993-09-07 Mcneilab Inc ２，３：４，５−ビス−Ｏ−（１−メチルエチリデン）−β−Ｄ−フルクトピラノースおよび（１−メチルシクロヘキシル）メタノールのクロロサルフエートおよびスルフアメート誘導体の製法
JP2002537326A (ja) * 1999-02-24 2002-11-05 ユニヴァーシティ・オブ・シンシナティ 衝動調節障害の治療のためのスルファメート誘導体の使用

Also Published As

Publication number Publication date
EP1581545A1 (en) 2005-10-05
ZA200506167B (en) 2007-03-28
PL377766A1 (pl) 2006-02-20
MXPA05007253A (es) 2005-12-14
UA82214C2 (en) 2008-03-25
WO2004063210A1 (en) 2004-07-29
IL169505A0 (en) 2007-07-04
NO20053673L (no) 2005-09-30
US7041650B2 (en) 2006-05-09
US20030176362A1 (en) 2003-09-18
KR20050092035A (ko) 2005-09-16
CN100528888C (zh) 2009-08-19
HRP20050603A2 (en) 2006-07-31
CN1735626A (zh) 2006-02-15
RU2330041C2 (ru) 2008-07-27
NZ540696A (en) 2007-11-30
CA2511682A1 (en) 2004-07-29
AU2003300149A1 (en) 2004-08-10
RU2005120782A (ru) 2006-01-20
NO20053673D0 (no) 2005-07-29

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