JP2006511555A - Ｃｃｒ５拮抗剤としての複素環式化合物 - Google Patents
Ｃｃｒ５拮抗剤としての複素環式化合物 Download PDFInfo
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Classifications
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
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- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
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Applications Claiming Priority (2)
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| US43341002P | 2002-12-13 | 2002-12-13 | |
| PCT/US2003/039740 WO2004055011A1 (en) | 2002-12-13 | 2003-12-12 | Heterocyclic compounds as ccr5 antagonists |
Publications (2)
| Publication Number | Publication Date |
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| JP2006511555A true JP2006511555A (ja) | 2006-04-06 |
| JP2006511555A5 JP2006511555A5 (enExample) | 2007-01-11 |
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| JP (1) | JP2006511555A (enExample) |
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| ES (1) | ES2312856T3 (enExample) |
| WO (1) | WO2004055011A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2004054581A2 (en) * | 2002-12-13 | 2004-07-01 | Smithkline Beecham Corporation | Cyclohexyl compounds as ccr5 antagonists |
| WO2008030853A2 (en) * | 2006-09-06 | 2008-03-13 | Incyte Corporation | Combination therapy for human immunodeficiency virus infection |
| CN104530048B (zh) | 2008-08-11 | 2016-09-14 | 葛兰素史密丝克莱恩有限责任公司 | 腺嘌呤衍生物 |
| UA103195C2 (uk) | 2008-08-11 | 2013-09-25 | Глаксосмитклайн Ллк | Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань |
| JP2011530562A (ja) | 2008-08-11 | 2011-12-22 | グラクソスミスクライン エルエルシー | アレルギー性、炎症性及び感染性疾患治療用のプリン誘導体 |
| ES2564457T3 (es) * | 2009-07-24 | 2016-03-22 | Glaxosmithkline Llc | Derivados de azabiciclo[3,2,1]octilo para su uso en el tratamiento de VIH |
| CA2786973C (en) | 2010-02-10 | 2018-04-10 | Robert Hermann Gibbon | 6-amino-2-{[(1s)-1-methylbutyl] oxy}-9-[5-(1-piperidinyl)-7,9-dihydro-8h-purin-8-one maleate |
| JP2013519644A (ja) | 2010-02-10 | 2013-05-30 | グラクソスミスクライン エルエルシー | プリン誘導体およびそれらの薬学的使用 |
| JO3387B1 (ar) | 2011-12-16 | 2019-03-13 | Glaxosmithkline Llc | مشتقات بيتولين |
| CN106029668B (zh) | 2014-02-20 | 2018-02-23 | 葛兰素史克知识产权第二有限公司 | 吡咯并[3,2]嘧啶衍生物作为人类干扰素诱导剂 |
| MX2017006302A (es) | 2014-11-13 | 2018-02-16 | Glaxosmithkline Biologicals Sa | Derivados de adenina que son utiles en el tratamiento de enfermedades alergicas u otras afecciones inflamatorias. |
| CR20180286A (es) | 2015-12-03 | 2018-07-16 | Glaxosmithkline Ip Dev Ltd | Dinucleotidos de purina cíclicos como moduladores de sting |
| US10239847B1 (en) | 2016-03-03 | 2019-03-26 | Cellactin | Method for 2-oxothiazolidine-4-carboxylic acid for cellular glutathione |
| SI3440076T1 (sl) | 2016-04-07 | 2022-09-30 | Glaxosmithkline Intellectual Property Development Limited | Heterociklični amidi uporabni kot proteinski modulatorji |
| BR112018070602A2 (pt) | 2016-04-07 | 2019-02-05 | Glaxosmithkline Ip Dev Ltd | composto, composição farmacêutica, uso do composto, e, método para tratar uma doença ou distúrbio |
| JP7291130B2 (ja) | 2017-10-05 | 2023-06-14 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド | インターフェロン遺伝子の刺激物質（ｓｔｉｎｇ）の調節物質 |
| TW201927771A (zh) | 2017-10-05 | 2019-07-16 | 英商葛蘭素史密斯克藍智慧財產發展有限公司 | 可作為蛋白質調節劑之雜環醯胺及其使用方法 |
| GB201807924D0 (en) | 2018-05-16 | 2018-06-27 | Ctxt Pty Ltd | Compounds |
| CN109593089B (zh) * | 2019-01-24 | 2022-01-28 | 西南大学 | 二氮杂螺癸烷哌啶甲酰胺类化合物制备和应用 |
| JP2022533194A (ja) | 2019-05-16 | 2022-07-21 | スティングセラ インコーポレイテッド | ベンゾ［ｂ］［１，８］ナフチリジン酢酸誘導体および使用方法 |
| EP3969438A1 (en) | 2019-05-16 | 2022-03-23 | Stingthera, Inc. | Oxoacridinyl acetic acid derivatives and methods of use |
| GB201910304D0 (en) | 2019-07-18 | 2019-09-04 | Ctxt Pty Ltd | Compounds |
| GB201910305D0 (en) | 2019-07-18 | 2019-09-04 | Ctxt Pty Ltd | Compounds |
| AU2020409429A1 (en) | 2019-12-18 | 2022-06-16 | Ctxt Pty Ltd | Compounds |
| US11116737B1 (en) | 2020-04-10 | 2021-09-14 | University Of Georgia Research Foundation, Inc. | Methods of using probenecid for treatment of coronavirus infections |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11507324A (ja) * | 1995-01-30 | 1999-06-29 | サノフィ | 置換されたヘテロ環化合物、これらを製造する方法、及びこれらが存在する薬学的組成物 |
| JP2002540195A (ja) * | 1999-03-25 | 2002-11-26 | サノフィ−サンテラボ | 新規なモルホリン誘導体、その製造方法、およびそれを含む製剤 |
| WO2002094821A1 (fr) * | 2001-05-21 | 2002-11-28 | Sanofi-Synthelabo | Nouveaux derives de piperidinecarboxamide, un procede pour leur preparation et les compositions pharmaceutiques les contenant |
| JP2004525157A (ja) * | 2001-03-29 | 2004-08-19 | シェーリング コーポレイション | Ａｉｄｓの処置に有用なｃｃｒ５アンタゴニスト |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6431570A (en) * | 1987-07-27 | 1989-02-01 | Matsubara Kk | Sand bold transfer type casting method |
| WO2002005819A1 (en) * | 2000-07-15 | 2002-01-24 | Smithkline Beecham Corporation | Compounds and methods |
| GB0108876D0 (en) * | 2001-04-09 | 2001-05-30 | Novartis Ag | Organic Compounds |
-
2003
- 2003-12-12 DE DE60324014T patent/DE60324014D1/de not_active Expired - Lifetime
- 2003-12-12 WO PCT/US2003/039740 patent/WO2004055011A1/en not_active Ceased
- 2003-12-12 AU AU2003300911A patent/AU2003300911A1/en not_active Abandoned
- 2003-12-12 AT AT03813436T patent/ATE410426T1/de not_active IP Right Cessation
- 2003-12-12 JP JP2004560858A patent/JP2006511555A/ja active Pending
- 2003-12-12 US US10/538,145 patent/US7452992B2/en not_active Expired - Fee Related
- 2003-12-12 EP EP03813436A patent/EP1569931B1/en not_active Expired - Lifetime
- 2003-12-12 ES ES03813436T patent/ES2312856T3/es not_active Expired - Lifetime
-
2008
- 2008-10-15 US US12/251,639 patent/US20090053172A1/en not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11507324A (ja) * | 1995-01-30 | 1999-06-29 | サノフィ | 置換されたヘテロ環化合物、これらを製造する方法、及びこれらが存在する薬学的組成物 |
| JP2002540195A (ja) * | 1999-03-25 | 2002-11-26 | サノフィ−サンテラボ | 新規なモルホリン誘導体、その製造方法、およびそれを含む製剤 |
| JP2004525157A (ja) * | 2001-03-29 | 2004-08-19 | シェーリング コーポレイション | Ａｉｄｓの処置に有用なｃｃｒ５アンタゴニスト |
| WO2002094821A1 (fr) * | 2001-05-21 | 2002-11-28 | Sanofi-Synthelabo | Nouveaux derives de piperidinecarboxamide, un procede pour leur preparation et les compositions pharmaceutiques les contenant |
Also Published As
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|---|---|
| US20090053172A1 (en) | 2009-02-26 |
| DE60324014D1 (de) | 2008-11-20 |
| AU2003300911A1 (en) | 2004-07-09 |
| US20060052595A1 (en) | 2006-03-09 |
| EP1569931B1 (en) | 2008-10-08 |
| ATE410426T1 (de) | 2008-10-15 |
| WO2004055011A1 (en) | 2004-07-01 |
| ES2312856T3 (es) | 2009-03-01 |
| EP1569931A1 (en) | 2005-09-07 |
| US7452992B2 (en) | 2008-11-18 |
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