JP2006511538A - 非ヌクレオシド系逆転写酵素阻害剤（ｎｎｒｔｉ）とプロテアーゼ阻害剤などのシトクロムｐ４５０の阻害剤とを含む組み合わせの使用 - Google Patents
非ヌクレオシド系逆転写酵素阻害剤（ｎｎｒｔｉ）とプロテアーゼ阻害剤などのシトクロムｐ４５０の阻害剤とを含む組み合わせの使用 Download PDFInfo
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- JP2006511538A JP2006511538A JP2004560402A JP2004560402A JP2006511538A JP 2006511538 A JP2006511538 A JP 2006511538A JP 2004560402 A JP2004560402 A JP 2004560402A JP 2004560402 A JP2004560402 A JP 2004560402A JP 2006511538 A JP2006511538 A JP 2006511538A
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
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| EP1944042A1 (en) | 2003-10-27 | 2008-07-16 | Vertex Pharmceuticals Incorporated | Combinations for HCV treatment |
| US7388008B2 (en) | 2004-08-02 | 2008-06-17 | Ambrilia Biopharma Inc. | Lysine based compounds |
| US20060287316A1 (en) * | 2005-04-27 | 2006-12-21 | Ambrilia Biopharma Inc. | Method for improving pharmacokinetics of protease inhibitors and protease inhibitor precursors |
| WO2007062526A1 (en) | 2005-11-30 | 2007-06-07 | Ambrilia Biopharma Inc. | Lysine-based prodrugs of aspartyl protease inhibitors and processes for their preparation |
| CN1907138B (zh) * | 2006-08-11 | 2011-01-12 | 华南师范大学 | 一种沙田柚子汁提取物及其提取方法和应用 |
| ES2628730T3 (es) | 2006-09-21 | 2017-08-03 | Taimed Biologics, Inc. | Inhibidores de proteasa |
| SG174146A1 (en) | 2009-02-27 | 2011-10-28 | Enanta Pharm Inc | Hepatitis c virus inhibitors |
| LT2421527T (lt) * | 2009-04-25 | 2018-09-10 | F. Hoffmann-La Roche Ag | Farmakokinetinių savybių pagerinimo būdai |
| CA2761650C (en) | 2009-05-13 | 2015-05-26 | Enanta Pharmaceuticals, Inc. | Macrocyclic compounds as hepatitis c virus inhibitors |
| US8653070B2 (en) | 2009-12-14 | 2014-02-18 | Enanta Pharmaceuticals, Inc. | Hepatitis C virus inhibitors |
| WO2014013014A1 (en) | 2012-07-18 | 2014-01-23 | Fundació Privada Centre De Regulació Genòmica (Crg) | Jak inhibitors for activation of epidermal stem cell populations |
| WO2018041989A1 (en) | 2016-09-02 | 2018-03-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for diagnosing and treating refractory celiac disease type 2 |
| WO2020201362A2 (en) | 2019-04-02 | 2020-10-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods of predicting and preventing cancer in patients having premalignant lesions |
| WO2020212395A1 (en) | 2019-04-16 | 2020-10-22 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Use of jak inhibitors for the treatment of painful conditions involving nav1.7 channels |
| US20250283174A1 (en) | 2022-05-16 | 2025-09-11 | Institut National de la Santé et de la Recherche Médicale | Methods for assessing the exhaustion of hematopoietic stem cells induced by chronic inflammation |
| WO2026093435A1 (en) | 2024-10-31 | 2026-05-07 | Institut National de la Santé et de la Recherche Médicale | Use of jak inhibitors for enhancing the potency of immunotherapy in the treament of cancer |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11508884A (ja) * | 1995-06-29 | 1999-08-03 | アボツト・ラボラトリーズ | エイズを処置する方法におけるチトクロームｐ４５０により代謝される薬物の薬物動態を改善するためのリトナビル（ａｂｔ−５３８）の使用 |
| WO2001096338A1 (en) * | 2000-06-16 | 2001-12-20 | Boehringer Ingelheim (Canada) Ltd. | Non-nucleoside reverse transcriptase inhibitors |
| JP2002528502A (ja) * | 1998-11-04 | 2002-09-03 | ファルマシア・アンド・アップジョン・カンパニー | チプラナビルの薬物動態を改善する方法 |
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|---|---|---|---|---|
| US5696270A (en) * | 1989-05-23 | 1997-12-09 | Abbott Laboratories | Intermediate for making retroviral protease inhibiting compounds |
| IL111991A (en) * | 1994-01-28 | 2000-07-26 | Abbott Lab | Liquid pharmaceutical composition of HIV protease inhibitors in organic solvent |
| CA2285577A1 (en) * | 1997-04-07 | 1998-10-15 | Triangle Pharmaceuticals, Inc. | Compositions containing mkc-442 in combination with other antiviral agents |
| US6391919B1 (en) * | 2000-01-12 | 2002-05-21 | Bristol-Myers Squibb Pharma Company | Bis-amino acid sulfonamides containing substituted benzyl amines HIV protease inhibitors |
| DE60306539T2 (de) * | 2002-09-19 | 2007-07-19 | Boehringer Ingelheim (Canada) Ltd., Laval | Nicht-nukleosidische inhibitoren der reverse transkriptase |
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2005
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH11508884A (ja) * | 1995-06-29 | 1999-08-03 | アボツト・ラボラトリーズ | エイズを処置する方法におけるチトクロームｐ４５０により代謝される薬物の薬物動態を改善するためのリトナビル（ａｂｔ−５３８）の使用 |
| JP2002528502A (ja) * | 1998-11-04 | 2002-09-03 | ファルマシア・アンド・アップジョン・カンパニー | チプラナビルの薬物動態を改善する方法 |
| WO2001096338A1 (en) * | 2000-06-16 | 2001-12-20 | Boehringer Ingelheim (Canada) Ltd. | Non-nucleoside reverse transcriptase inhibitors |
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| JPN6010024829, 桑原 健, "ＨＩＶ感染症の治療５ 薬物動態と抗ＨＩＶ療法", 治療学, 2001, ｖｏｌ．３５ ｎｏ．２, 第１４９〜１５６頁, JP * |
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200502947B (en) | 2008-01-30 |
| ECSP055854A (es) | 2006-01-16 |
| UA81003C2 (en) | 2007-11-26 |
| CN1726041A (zh) | 2006-01-25 |
| MXPA05005773A (es) | 2005-08-16 |
| NO20053455L (no) | 2005-08-10 |
| KR20050085681A (ko) | 2005-08-29 |
| BR0317095A (pt) | 2005-10-25 |
| HRP20050557A2 (en) | 2006-05-31 |
| EA200500894A1 (ru) | 2006-02-24 |
| IL169099A0 (en) | 2007-07-04 |
| CA2510143A1 (en) | 2004-07-01 |
| WO2004054586A1 (en) | 2004-07-01 |
| EP1575595A1 (en) | 2005-09-21 |
| RS20050461A (sr) | 2007-08-03 |
| US20080096832A1 (en) | 2008-04-24 |
| US20040152625A1 (en) | 2004-08-05 |
| AU2003296647A1 (en) | 2004-07-09 |
| NZ541187A (en) | 2007-12-21 |
| PL376900A1 (pl) | 2006-01-09 |
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