JP2006510348A5 - - Google Patents

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Publication number
JP2006510348A5
JP2006510348A5 JP2004523488A JP2004523488A JP2006510348A5 JP 2006510348 A5 JP2006510348 A5 JP 2006510348A5 JP 2004523488 A JP2004523488 A JP 2004523488A JP 2004523488 A JP2004523488 A JP 2004523488A JP 2006510348 A5 JP2006510348 A5 JP 2006510348A5
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JP
Japan
Prior art keywords
group
nucleic acid
acid probe
fluorescence
fluorescence quenching
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Pending
Application number
JP2004523488A
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English (en)
Japanese (ja)
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JP2006510348A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2003/022320 external-priority patent/WO2004010101A2/en
Publication of JP2006510348A publication Critical patent/JP2006510348A/ja
Publication of JP2006510348A5 publication Critical patent/JP2006510348A5/ja
Pending legal-status Critical Current

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JP2004523488A 2002-07-18 2003-07-17 蛍光消光脱離基を用いる化学ライゲーションの検出 Pending JP2006510348A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39677402P 2002-07-18 2002-07-18
PCT/US2003/022320 WO2004010101A2 (en) 2002-07-18 2003-07-17 Detection of chemical ligation using fluorescence quenching leaving groups

Publications (2)

Publication Number Publication Date
JP2006510348A JP2006510348A (ja) 2006-03-30
JP2006510348A5 true JP2006510348A5 (cg-RX-API-DMAC7.html) 2008-08-14

Family

ID=30770949

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004523488A Pending JP2006510348A (ja) 2002-07-18 2003-07-17 蛍光消光脱離基を用いる化学ライゲーションの検出

Country Status (6)

Country Link
US (1) US7749699B2 (cg-RX-API-DMAC7.html)
EP (1) EP1543156A4 (cg-RX-API-DMAC7.html)
JP (1) JP2006510348A (cg-RX-API-DMAC7.html)
AU (1) AU2003256587A1 (cg-RX-API-DMAC7.html)
CA (1) CA2492048A1 (cg-RX-API-DMAC7.html)
WO (1) WO2004010101A2 (cg-RX-API-DMAC7.html)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7033753B1 (en) * 1999-01-15 2006-04-25 University Of Rochester Compositions and methods for nonenzymatic ligation of oligonucleotides and detection of genetic polymorphisms
US7745614B2 (en) 2004-09-03 2010-06-29 The Board Of Trustees Of The Leland Stanford Junior University Universal linker compositions for the release or transfer of chemical agents from a polynucleotide
BRPI0611474A2 (pt) * 2005-05-26 2010-09-14 Ensemble Discovery Corp biodetecção por quìmica modelada com ácido nucléico
WO2007133703A2 (en) * 2006-05-10 2007-11-22 Dxterity Diagnostics Detection of nucleic acid targets using chemically reactive oligonucleotide probes
JP2008259453A (ja) * 2007-04-12 2008-10-30 Toyobo Co Ltd 核酸の検出方法
SG173627A1 (en) 2009-02-13 2011-09-29 Chem Inc X Methods of creating and screening dna-encoded libraries
WO2010114599A1 (en) * 2009-04-01 2010-10-07 Dx Terity Diagnostics Inc. Chemical ligation dependent probe amplification (clpa)
US10066257B2 (en) 2010-03-29 2018-09-04 Dxterity Diagnostics Incorporated Methods and compositions for detecting target nucleic acids
US9845495B2 (en) 2010-12-10 2017-12-19 Abbott Laboratories Method and kit for detecting target nucleic acid
US20140170653A1 (en) 2011-04-15 2014-06-19 Life Technologies Corporation Chemical ligation
DK2748357T3 (en) 2011-09-07 2018-07-16 X Chem Inc Methods for labeling DNA-encoded libraries
KR102146721B1 (ko) 2012-07-13 2020-08-21 엑스-켐, 인크. 폴리머라제에 의해 판독가능하지 않은 코딩 올리고뉴클레오티드 연결을 갖는 dna-코딩된 라이브러리
CN105659091A (zh) 2013-08-19 2016-06-08 卓异生物公司 用于单分子检测的测定及其应用
CA2936157C (en) 2014-01-15 2021-08-24 Tokyo Institute Of Technology Covered sequence conversion dna and detection methods
WO2015191777A2 (en) 2014-06-10 2015-12-17 Dxterity Diagnostics Incorporated Devices and methods for collecting and stabilizing biological samples
CN107075585B (zh) * 2014-10-14 2021-07-20 雅培实验室 具有锁核酸的序列转换和信号扩增dna以及使用其的检测方法
ES2791280T3 (es) 2014-12-24 2020-11-03 Abbott Lab Método de detección, composición y kit basados en reacciones en cascada de ADN amplificador de señal con extensión de la diana
WO2016134191A1 (en) 2015-02-18 2016-08-25 Singular Bio, Inc. Assays for single molecule detection and use thereof
CN108350487B (zh) * 2015-11-19 2022-05-27 加利福尼亚太平洋生物科学股份有限公司 用于改善信号检测的化合物和系统

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5476925A (en) * 1993-02-01 1995-12-19 Northwestern University Oligodeoxyribonucleotides including 3'-aminonucleoside-phosphoramidate linkages and terminal 3'-amino groups
ES2204913T3 (es) * 1993-04-12 2004-05-01 Northwestern University Metodo para formacion de oligonucleotidos.
US5681943A (en) * 1993-04-12 1997-10-28 Northwestern University Method for covalently linking adjacent oligonucleotides
US5925517A (en) * 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
CA2219891C (en) * 1995-05-05 2002-01-29 Applied Biosystems, Llc Methods and reagents for combined pcr amplification and hybridization probing assay
US6080868A (en) * 1998-01-23 2000-06-27 The Perkin-Elmer Corporation Nitro-substituted non-fluorescent asymmetric cyanine dye compounds
US5952202A (en) * 1998-03-26 1999-09-14 The Perkin Elmer Corporation Methods using exogenous, internal controls and analogue blocks during nucleic acid amplification

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