JP2006507816A5 - - Google Patents
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- Publication number
- JP2006507816A5 JP2006507816A5 JP2004547020A JP2004547020A JP2006507816A5 JP 2006507816 A5 JP2006507816 A5 JP 2006507816A5 JP 2004547020 A JP2004547020 A JP 2004547020A JP 2004547020 A JP2004547020 A JP 2004547020A JP 2006507816 A5 JP2006507816 A5 JP 2006507816A5
- Authority
- JP
- Japan
- Prior art keywords
- eif
- apoptosis
- tissue
- specific eif
- expression level
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102100026761 Eukaryotic translation initiation factor 5A-1 Human genes 0.000 claims 15
- 108010085279 eukaryotic translation initiation factor 5A Proteins 0.000 claims 15
- 230000014509 gene expression Effects 0.000 claims 11
- 108010092776 Autophagy-Related Protein 5 Proteins 0.000 claims 9
- 102000016614 Autophagy-Related Protein 5 Human genes 0.000 claims 9
- 210000001519 tissue Anatomy 0.000 claims 8
- 230000002062 proliferating effect Effects 0.000 claims 6
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 210000005003 heart tissue Anatomy 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 108091034117 Oligonucleotide Proteins 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 208000028867 ischemia Diseases 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 238000012216 screening Methods 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 1
- 239000000074 antisense oligonucleotide Substances 0.000 claims 1
- 238000012230 antisense oligonucleotides Methods 0.000 claims 1
- 230000006907 apoptotic process Effects 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/277,969 US7217517B2 (en) | 2001-07-23 | 2002-10-23 | Nucleic acids, polypeptides, and methods for modulating apoptosis |
| US10/277,969 | 2002-10-23 | ||
| PCT/US2003/033463 WO2004037984A2 (en) | 2002-10-23 | 2003-10-22 | Nucleic acids, polypeptides, and methods for modulating apoptosis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006507816A JP2006507816A (ja) | 2006-03-09 |
| JP2006507816A5 true JP2006507816A5 (https=) | 2006-12-07 |
| JP4890763B2 JP4890763B2 (ja) | 2012-03-07 |
Family
ID=32174556
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004547020A Expired - Fee Related JP4890763B2 (ja) | 2002-10-23 | 2003-10-22 | アポトーシスを調節するための核酸、ポリペプチド、及びアポトーシスを調節する方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7217517B2 (https=) |
| EP (1) | EP1578452B1 (https=) |
| JP (1) | JP4890763B2 (https=) |
| KR (1) | KR20050046015A (https=) |
| CN (1) | CN1732018B (https=) |
| AT (1) | ATE384740T1 (https=) |
| AU (1) | AU2003301585B2 (https=) |
| CA (1) | CA2503442C (https=) |
| DE (1) | DE60318900D1 (https=) |
| NZ (1) | NZ540105A (https=) |
| TW (1) | TWI324070B (https=) |
| WO (1) | WO2004037984A2 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7166467B2 (en) * | 2001-07-23 | 2007-01-23 | Senesco Technologies, Inc. | Nucleic acids, polypeptides, compositions, and methods for modulating apoptosis |
| TW200427695A (en) * | 2003-03-05 | 2004-12-16 | Senesco Technologies Inc | Use of antisense oligonucleotides or sirna to suppress expression of eif-5a1 |
| US20140371299A1 (en) * | 2004-06-07 | 2014-12-18 | Senesco Technologies, Inc. | Use of Apoptosis-Specific elF-5A siRNA to Down Regulate Expression of Proinflammatory Cytokines to Treat Sepsis |
| NZ552692A (en) * | 2004-07-20 | 2010-08-27 | Senesco Technologies Inc | Use of apoptosis-specific EIF-5A sirnas for the manufacture of a medicament for use in the treatment of a disease treatable by suppression of the JAK/STAT pathway. |
| CA2588129A1 (en) * | 2004-12-03 | 2006-06-08 | Senesco Technologies, Inc. | Apoptosis-specific eif-5a and polynucleotides encoding same |
| EP1824982A2 (en) * | 2004-12-03 | 2007-08-29 | Senesco Technologies, Inc. | Methods of increasing seed yield |
| US8492521B2 (en) | 2008-05-27 | 2013-07-23 | Yoshinori Seko | Oxidative stress responsive apoptosis inducing protein eIF5A |
| CN111579784B (zh) | 2014-11-07 | 2023-12-22 | 藤仓化成株式会社 | 以dhps基因作为指标使用的动脉硬化及癌的检测方法 |
| CA3103265A1 (en) * | 2018-06-12 | 2019-12-19 | Angiex, Inc. | Antibody-oligonucleotide conjugates |
| CN114231551B (zh) * | 2021-12-24 | 2023-09-29 | 云南大学 | 蛋白在促进昆虫淋巴细胞凋亡和/或防治害虫中的应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5344846A (en) | 1992-12-30 | 1994-09-06 | The United States Of America As Represented By The Department Of Health And Human Services | Compositions and methods for inhibiting deoxyhypusine synthase and the growth of cells |
| IL117113A0 (en) * | 1995-02-13 | 1996-06-18 | Sandoz Ag | Mutant proteins |
| US5849587A (en) | 1995-06-09 | 1998-12-15 | Cornell Research Foundation, Inc. | Method of inhibiting viral replication in eukaryotic cells and of inducing apoptosis of virally-infected cells |
| WO1999001551A2 (en) | 1997-06-30 | 1999-01-14 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Novel inhibitor of cellular proliferation |
| US6538182B1 (en) | 1999-07-06 | 2003-03-25 | Senesco, Inc. | DNA encoding a plant deoxyhypusine synthase, a plant eukaryotic initiation factor 5A, transgenic plants and a method for controlling senescence programmed and cell death in plants |
| CA2376065A1 (en) | 1999-08-06 | 2001-02-15 | Pharmacia & Upjohn Company | Crystallization and structure determination of staphylococcus aureus elongation factor p |
| US7166467B2 (en) | 2001-07-23 | 2007-01-23 | Senesco Technologies, Inc. | Nucleic acids, polypeptides, compositions, and methods for modulating apoptosis |
-
2002
- 2002-10-23 US US10/277,969 patent/US7217517B2/en not_active Expired - Fee Related
-
2003
- 2003-10-22 JP JP2004547020A patent/JP4890763B2/ja not_active Expired - Fee Related
- 2003-10-22 NZ NZ540105A patent/NZ540105A/en unknown
- 2003-10-22 AU AU2003301585A patent/AU2003301585B2/en not_active Ceased
- 2003-10-22 DE DE60318900T patent/DE60318900D1/de not_active Expired - Lifetime
- 2003-10-22 KR KR1020057006733A patent/KR20050046015A/ko not_active Ceased
- 2003-10-22 CN CN200380107399.3A patent/CN1732018B/zh not_active Expired - Fee Related
- 2003-10-22 EP EP03809607A patent/EP1578452B1/en not_active Expired - Lifetime
- 2003-10-22 CA CA2503442A patent/CA2503442C/en not_active Expired - Fee Related
- 2003-10-22 WO PCT/US2003/033463 patent/WO2004037984A2/en not_active Ceased
- 2003-10-22 AT AT03809607T patent/ATE384740T1/de not_active IP Right Cessation
- 2003-10-23 TW TW092129428A patent/TWI324070B/zh not_active IP Right Cessation
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