NZ540105A - Comparing the expression level of apoptosis-specific eIF-5A with the expression levels of proliferating eIF-5A for identifying an incidence of ischemia and reducing apoptosis in mammalian tissue - Google Patents
Comparing the expression level of apoptosis-specific eIF-5A with the expression levels of proliferating eIF-5A for identifying an incidence of ischemia and reducing apoptosis in mammalian tissueInfo
- Publication number
- NZ540105A NZ540105A NZ540105A NZ54010503A NZ540105A NZ 540105 A NZ540105 A NZ 540105A NZ 540105 A NZ540105 A NZ 540105A NZ 54010503 A NZ54010503 A NZ 54010503A NZ 540105 A NZ540105 A NZ 540105A
- Authority
- NZ
- New Zealand
- Prior art keywords
- apoptosis
- eif
- cells
- specific
- phm6
- Prior art date
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4747—Apoptosis related proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/277,969 US7217517B2 (en) | 2001-07-23 | 2002-10-23 | Nucleic acids, polypeptides, and methods for modulating apoptosis |
| PCT/US2003/033463 WO2004037984A2 (en) | 2002-10-23 | 2003-10-22 | Nucleic acids, polypeptides, and methods for modulating apoptosis |
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| NZ540105A true NZ540105A (en) | 2006-10-27 |
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| NZ540105A NZ540105A (en) | 2002-10-23 | 2003-10-22 | Comparing the expression level of apoptosis-specific eIF-5A with the expression levels of proliferating eIF-5A for identifying an incidence of ischemia and reducing apoptosis in mammalian tissue |
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| US (1) | US7217517B2 (https=) |
| EP (1) | EP1578452B1 (https=) |
| JP (1) | JP4890763B2 (https=) |
| KR (1) | KR20050046015A (https=) |
| CN (1) | CN1732018B (https=) |
| AT (1) | ATE384740T1 (https=) |
| AU (1) | AU2003301585B2 (https=) |
| CA (1) | CA2503442C (https=) |
| DE (1) | DE60318900D1 (https=) |
| NZ (1) | NZ540105A (https=) |
| TW (1) | TWI324070B (https=) |
| WO (1) | WO2004037984A2 (https=) |
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| US7166467B2 (en) * | 2001-07-23 | 2007-01-23 | Senesco Technologies, Inc. | Nucleic acids, polypeptides, compositions, and methods for modulating apoptosis |
| AU2004217437B2 (en) * | 2003-03-05 | 2009-11-19 | Senesco Technologies, Inc. | Use of antisense oligonucleotides or siRNA to suppress expression of eIF-5A1 |
| US20140371299A1 (en) * | 2004-06-07 | 2014-12-18 | Senesco Technologies, Inc. | Use of Apoptosis-Specific elF-5A siRNA to Down Regulate Expression of Proinflammatory Cytokines to Treat Sepsis |
| AU2005269647B2 (en) * | 2004-07-20 | 2009-11-12 | Senesco Technologies, Inc. | Use of apoptosis-specific eIF-5A siRNAs and antisense polynucleotides to inhibit/suppress an inflammatory response |
| CA2588129A1 (en) * | 2004-12-03 | 2006-06-08 | Senesco Technologies, Inc. | Apoptosis-specific eif-5a and polynucleotides encoding same |
| EP1824982A2 (en) * | 2004-12-03 | 2007-08-29 | Senesco Technologies, Inc. | Methods of increasing seed yield |
| JP5578522B2 (ja) * | 2008-05-27 | 2014-08-27 | 義規 世古 | アポトーシス誘導薬 |
| KR102441107B1 (ko) | 2014-11-07 | 2022-09-13 | 후지쿠라 가세이 가부시키가이샤 | 데옥시하이푸신·신타제 유전자를 지표로서 사용하는 동맥 경화 및 암의 검출 방법 |
| EP3807644A4 (en) * | 2018-06-12 | 2022-07-06 | Angiex, Inc. | ANTIBODY-OLIGONUCLEOTIDE CONJUGATES |
| CN114231551B (zh) * | 2021-12-24 | 2023-09-29 | 云南大学 | 蛋白在促进昆虫淋巴细胞凋亡和/或防治害虫中的应用 |
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| US5344846A (en) | 1992-12-30 | 1994-09-06 | The United States Of America As Represented By The Department Of Health And Human Services | Compositions and methods for inhibiting deoxyhypusine synthase and the growth of cells |
| AU4665196A (en) * | 1995-02-13 | 1996-09-04 | Novartis Ag | Eukaryotic initiation factor 5A (eIF-5A) mutants |
| US5849587A (en) | 1995-06-09 | 1998-12-15 | Cornell Research Foundation, Inc. | Method of inhibiting viral replication in eukaryotic cells and of inducing apoptosis of virally-infected cells |
| CA2296105A1 (en) | 1997-06-30 | 1999-01-14 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Novel inhibitor of cellular proliferation |
| US6538182B1 (en) | 1999-07-06 | 2003-03-25 | Senesco, Inc. | DNA encoding a plant deoxyhypusine synthase, a plant eukaryotic initiation factor 5A, transgenic plants and a method for controlling senescence programmed and cell death in plants |
| CA2376065A1 (en) | 1999-08-06 | 2001-02-15 | Pharmacia & Upjohn Company | Crystallization and structure determination of staphylococcus aureus elongation factor p |
| US7166467B2 (en) | 2001-07-23 | 2007-01-23 | Senesco Technologies, Inc. | Nucleic acids, polypeptides, compositions, and methods for modulating apoptosis |
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2002
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- 2003-10-22 CN CN200380107399.3A patent/CN1732018B/zh not_active Expired - Fee Related
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| WO2004037984A2 (en) | 2004-05-06 |
| KR20050046015A (ko) | 2005-05-17 |
| EP1578452A2 (en) | 2005-09-28 |
| US7217517B2 (en) | 2007-05-15 |
| TWI324070B (en) | 2010-05-01 |
| AU2003301585A1 (en) | 2004-05-13 |
| DE60318900D1 (de) | 2008-03-13 |
| JP2006507816A (ja) | 2006-03-09 |
| CN1732018B (zh) | 2014-09-10 |
| ATE384740T1 (de) | 2008-02-15 |
| JP4890763B2 (ja) | 2012-03-07 |
| EP1578452B1 (en) | 2008-01-23 |
| TW200501988A (en) | 2005-01-16 |
| CA2503442A1 (en) | 2004-05-06 |
| CN1732018A (zh) | 2006-02-08 |
| EP1578452A4 (en) | 2006-01-11 |
| CA2503442C (en) | 2014-02-18 |
| WO2004037984A3 (en) | 2005-04-14 |
| US20030144238A1 (en) | 2003-07-31 |
| AU2003301585B2 (en) | 2009-08-20 |
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