JP2006507359A - 心循環器疾患の治療のためのグリコーゲンホスホリラーゼ阻害剤の使用 - Google Patents
心循環器疾患の治療のためのグリコーゲンホスホリラーゼ阻害剤の使用 Download PDFInfo
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- JP2006507359A JP2006507359A JP2005501508A JP2005501508A JP2006507359A JP 2006507359 A JP2006507359 A JP 2006507359A JP 2005501508 A JP2005501508 A JP 2005501508A JP 2005501508 A JP2005501508 A JP 2005501508A JP 2006507359 A JP2006507359 A JP 2006507359A
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- alkyl
- phthalic acid
- phenoxy
- hydroxy
- halogen
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- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims description 2
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- UHFWEDDFLFAJHG-UHFFFAOYSA-N 1-(2-aminoethyl)-2-(hydroxymethyl)pyrrolidine-3,4-diol Chemical compound NCCN1CC(O)C(O)C1CO UHFWEDDFLFAJHG-UHFFFAOYSA-N 0.000 claims description 2
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- SBDAWMSBMQBJRA-UHFFFAOYSA-N 1-benzyl-2-(hydroxymethyl)pyrrolidine-3,4-diol Chemical compound OCC1C(O)C(O)CN1CC1=CC=CC=C1 SBDAWMSBMQBJRA-UHFFFAOYSA-N 0.000 claims description 2
- AORXTDSJOOFVRB-UHFFFAOYSA-N 1-butyl-2-(hydroxymethyl)pyrrolidine-3,4-diol Chemical compound CCCCN1CC(O)C(O)C1CO AORXTDSJOOFVRB-UHFFFAOYSA-N 0.000 claims description 2
- ITBZTMURQMEUAL-UHFFFAOYSA-N 2-(hydroxymethyl)-1-(2,2,2-trifluoroethyl)pyrrolidine-3,4-diol Chemical compound OCC1C(O)C(O)CN1CC(F)(F)F ITBZTMURQMEUAL-UHFFFAOYSA-N 0.000 claims description 2
- PXKLZLSYHLZPMK-UHFFFAOYSA-N 2-(hydroxymethyl)-1-propylpyrrolidine-3,4-diol Chemical compound CCCN1CC(O)C(O)C1CO PXKLZLSYHLZPMK-UHFFFAOYSA-N 0.000 claims description 2
- OQEBIHBLFRADNM-YUPRTTJUSA-N 2-hydroxymethyl-pyrrolidine-3,4-diol Chemical compound OC[C@@H]1NC[C@H](O)[C@H]1O OQEBIHBLFRADNM-YUPRTTJUSA-N 0.000 claims description 2
- FQOGWNRPPJMSEC-UHFFFAOYSA-N 3-(hydroxymethyl)piperidin-4-ol Chemical compound OCC1CNCCC1O FQOGWNRPPJMSEC-UHFFFAOYSA-N 0.000 claims description 2
- ITQKQYKCQXTDMI-UHFFFAOYSA-N 3-chloro-5-(hydroxymethyl)piperidin-4-ol Chemical compound OCC1CNCC(Cl)C1O ITQKQYKCQXTDMI-UHFFFAOYSA-N 0.000 claims description 2
- DQKZUKLPJVJMSG-UHFFFAOYSA-N 3-fluoro-5-(hydroxymethyl)piperidin-4-ol Chemical compound OCC1CNCC(F)C1O DQKZUKLPJVJMSG-UHFFFAOYSA-N 0.000 claims description 2
- DGBUIVDAWBSYNN-UHFFFAOYSA-N 4-(2-benzamidophenoxy)phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC=CC=C1 DGBUIVDAWBSYNN-UHFFFAOYSA-N 0.000 claims description 2
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- KNIRYHSJMHOIJZ-UHFFFAOYSA-N 4-[2-[[2-fluoro-5-(trifluoromethyl)benzoyl]amino]phenoxy]phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC(C(F)(F)F)=CC=C1F KNIRYHSJMHOIJZ-UHFFFAOYSA-N 0.000 claims description 2
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- AFJVJGBEGXWQNS-UHFFFAOYSA-N 4-[2-[[3-(trifluoromethyl)benzoyl]amino]phenoxy]phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC=CC(C(F)(F)F)=C1 AFJVJGBEGXWQNS-UHFFFAOYSA-N 0.000 claims description 2
- MKQSGNJOMQDZCH-UHFFFAOYSA-N 4-[4-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC(C=C1)=CC=C1NC(=O)C1=CC=CC([N+]([O-])=O)=C1 MKQSGNJOMQDZCH-UHFFFAOYSA-N 0.000 claims description 2
- BWWJUWJMTJBQPN-UHFFFAOYSA-N 4-[4-[(4-iodobenzoyl)amino]-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC(C(=C1)NC(=O)C=2C=C(C=CC=2)[N+]([O-])=O)=CC=C1NC(=O)C1=CC=C(I)C=C1 BWWJUWJMTJBQPN-UHFFFAOYSA-N 0.000 claims description 2
- UREVCBHMCDVYLI-UHFFFAOYSA-N 4-[4-acetamido-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C=1C=CC([N+]([O-])=O)=CC=1C(=O)NC1=CC(NC(=O)C)=CC=C1OC1=CC=C(C(O)=O)C(C(O)=O)=C1 UREVCBHMCDVYLI-UHFFFAOYSA-N 0.000 claims description 2
- GJXZFZQTSAOZSF-UHFFFAOYSA-N 4-[4-amino-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C=1C=CC([N+]([O-])=O)=CC=1C(=O)NC1=CC(N)=CC=C1OC1=CC=C(C(O)=O)C(C(O)=O)=C1 GJXZFZQTSAOZSF-UHFFFAOYSA-N 0.000 claims description 2
- UITDURQSKACGOI-UHFFFAOYSA-N 4-[4-benzamido-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC(C(=C1)NC(=O)C=2C=C(C=CC=2)[N+]([O-])=O)=CC=C1NC(=O)C1=CC=CC=C1 UITDURQSKACGOI-UHFFFAOYSA-N 0.000 claims description 2
- OAZBMVAPRVXFSM-UHFFFAOYSA-N 4-[4-bromo-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC1=CC=C(Br)C=C1NC(=O)C1=CC=CC([N+]([O-])=O)=C1 OAZBMVAPRVXFSM-UHFFFAOYSA-N 0.000 claims description 2
- JNEHUYVPZOKWNK-UHFFFAOYSA-N 4-[4-cyano-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC1=CC=C(C#N)C=C1NC(=O)C1=CC=CC([N+]([O-])=O)=C1 JNEHUYVPZOKWNK-UHFFFAOYSA-N 0.000 claims description 2
- SXQSXGKQUDBDKG-UHFFFAOYSA-N 4-[4-fluoro-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC1=CC=C(F)C=C1NC(=O)C1=CC=CC([N+]([O-])=O)=C1 SXQSXGKQUDBDKG-UHFFFAOYSA-N 0.000 claims description 2
- VIXZBRNAXCGCCC-UHFFFAOYSA-N 4-[4-methoxycarbonyl-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C=1C=CC([N+]([O-])=O)=CC=1C(=O)NC1=CC(C(=O)OC)=CC=C1OC1=CC=C(C(O)=O)C(C(O)=O)=C1 VIXZBRNAXCGCCC-UHFFFAOYSA-N 0.000 claims description 2
- JSWGGLZASDOWGM-UHFFFAOYSA-N 4-[4-methyl-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C=1C=CC([N+]([O-])=O)=CC=1C(=O)NC1=CC(C)=CC=C1OC1=CC=C(C(O)=O)C(C(O)=O)=C1 JSWGGLZASDOWGM-UHFFFAOYSA-N 0.000 claims description 2
- IVZCUPXQGWYXRH-UHFFFAOYSA-N 4-[5-fluoro-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC1=CC(F)=CC=C1NC(=O)C1=CC=CC([N+]([O-])=O)=C1 IVZCUPXQGWYXRH-UHFFFAOYSA-N 0.000 claims description 2
- AJYMAGBHSPVRBG-UHFFFAOYSA-N 4-[5-methyl-2-[(3-nitrobenzoyl)amino]phenoxy]phthalic acid Chemical compound C=1C=C(C(O)=O)C(C(O)=O)=CC=1OC1=CC(C)=CC=C1NC(=O)C1=CC=CC([N+]([O-])=O)=C1 AJYMAGBHSPVRBG-UHFFFAOYSA-N 0.000 claims description 2
- MCMVVHHPHOTFDO-UHFFFAOYSA-N 4-chloro-5-(hydroxymethyl)piperidin-3-ol Chemical compound OCC1CNCC(O)C1Cl MCMVVHHPHOTFDO-UHFFFAOYSA-N 0.000 claims description 2
- AMRGLJFRLTZTMG-UHFFFAOYSA-N 4-fluoro-5-(hydroxymethyl)piperidin-3-ol Chemical compound OCC1CNCC(O)C1F AMRGLJFRLTZTMG-UHFFFAOYSA-N 0.000 claims description 2
- VFYAZSTYKPFSFL-UHFFFAOYSA-N 4-{2,4-bis[(3-nitrobenzoyl)amino]phenoxy}phthalic acid Chemical compound C1=C(C(O)=O)C(C(=O)O)=CC=C1OC(C(=C1)NC(=O)C=2C=C(C=CC=2)[N+]([O-])=O)=CC=C1NC(=O)C1=CC=CC([N+]([O-])=O)=C1 VFYAZSTYKPFSFL-UHFFFAOYSA-N 0.000 claims description 2
- MMWSFXGSQAOMQI-UHFFFAOYSA-N 5-(2-hydroxyethyl)piperidine-3,4-diol Chemical compound OCCC1CNCC(O)C1O MMWSFXGSQAOMQI-UHFFFAOYSA-N 0.000 claims description 2
- KTXBXDGOZMHNIC-UHFFFAOYSA-N 5-(chloromethyl)piperidine-3,4-diol Chemical compound OC1CNCC(CCl)C1O KTXBXDGOZMHNIC-UHFFFAOYSA-N 0.000 claims description 2
- BEQPGACEJJJLEA-UHFFFAOYSA-N 5-(fluoromethyl)piperidine-3,4-diol Chemical compound OC1CNCC(CF)C1O BEQPGACEJJJLEA-UHFFFAOYSA-N 0.000 claims description 2
- WIWXVOPKTGFUMA-UHFFFAOYSA-M 5-(hydroxymethyl)-1,1-dimethylpiperidin-1-ium-3,4-diol;chloride Chemical compound [Cl-].C[N+]1(C)CC(O)C(O)C(CO)C1 WIWXVOPKTGFUMA-UHFFFAOYSA-M 0.000 claims description 2
- CYCTZRRPYHKVQQ-UHFFFAOYSA-N 5-(hydroxymethyl)-1-methylpiperidine-3,4-diol Chemical compound CN1CC(O)C(O)C(CO)C1 CYCTZRRPYHKVQQ-UHFFFAOYSA-N 0.000 claims description 2
- XCPUOKRBVCHXNS-UHFFFAOYSA-N 5-(hydroxymethyl)piperidin-3-ol Chemical compound OCC1CNCC(O)C1 XCPUOKRBVCHXNS-UHFFFAOYSA-N 0.000 claims description 2
- UIALTIIMHGHQRO-UHFFFAOYSA-N 5-ethylpiperidine-3,4-diol Chemical compound CCC1CNCC(O)C1O UIALTIIMHGHQRO-UHFFFAOYSA-N 0.000 claims description 2
- SOWLFRYBIBVUNW-UHFFFAOYSA-N 5-phenylpiperidine-3,4-diol Chemical compound OC1C(O)CNCC1C1=CC=CC=C1 SOWLFRYBIBVUNW-UHFFFAOYSA-N 0.000 claims description 2
- XVRLSSYAFOIBQU-UHFFFAOYSA-N 5-propan-2-ylpiperidine-3,4-diol Chemical compound CC(C)C1CNCC(O)C1O XVRLSSYAFOIBQU-UHFFFAOYSA-N 0.000 claims description 2
- KDHNIDSJJULIGE-UHFFFAOYSA-N 5-propylpiperidine-3,4-diol Chemical compound CCCC1CNCC(O)C1O KDHNIDSJJULIGE-UHFFFAOYSA-N 0.000 claims description 2
- ICJDWETZEPFXIX-KEWYIRBNSA-N CC[C@H]1OC(OC)[C@H](O)[C@@H](O)[C@@H]1O Chemical compound CC[C@H]1OC(OC)[C@H](O)[C@@H](O)[C@@H]1O ICJDWETZEPFXIX-KEWYIRBNSA-N 0.000 claims description 2
- 125000004218 chloromethyl group Chemical group [H]C([H])(Cl)* 0.000 claims description 2
- FCXGEEJWNLHSQW-UHFFFAOYSA-N dimethyl 4-(2-benzamidophenoxy)benzene-1,2-dicarboxylate Chemical compound C1=C(C(=O)OC)C(C(=O)OC)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC=CC=C1 FCXGEEJWNLHSQW-UHFFFAOYSA-N 0.000 claims description 2
- FZDIOJAQYNNMDD-UHFFFAOYSA-N dimethyl 4-[2,4-bis[(3-nitrobenzoyl)amino]phenoxy]benzene-1,2-dicarboxylate Chemical compound C1=C(C(=O)OC)C(C(=O)OC)=CC=C1OC(C(=C1)NC(=O)C=2C=C(C=CC=2)[N+]([O-])=O)=CC=C1NC(=O)C1=CC=CC([N+]([O-])=O)=C1 FZDIOJAQYNNMDD-UHFFFAOYSA-N 0.000 claims description 2
- MUAOHNWPBPJTCX-UHFFFAOYSA-N dimethyl 4-[2-[(2,3-difluorobenzoyl)amino]phenoxy]benzene-1,2-dicarboxylate Chemical compound C1=C(C(=O)OC)C(C(=O)OC)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC=CC(F)=C1F MUAOHNWPBPJTCX-UHFFFAOYSA-N 0.000 claims description 2
- ZFDCKWGKMGHAHU-UHFFFAOYSA-N dimethyl 4-[2-[(2,4-difluorobenzoyl)amino]phenoxy]benzene-1,2-dicarboxylate Chemical compound C1=C(C(=O)OC)C(C(=O)OC)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC=C(F)C=C1F ZFDCKWGKMGHAHU-UHFFFAOYSA-N 0.000 claims description 2
- OVOVTEJWEVOJQA-UHFFFAOYSA-N dimethyl 4-[2-[(2,5-difluorobenzoyl)amino]phenoxy]benzene-1,2-dicarboxylate Chemical compound C1=C(C(=O)OC)C(C(=O)OC)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC(F)=CC=C1F OVOVTEJWEVOJQA-UHFFFAOYSA-N 0.000 claims description 2
- FOEMSVVLOJVPQA-UHFFFAOYSA-N dimethyl 4-[2-[(2-fluorobenzoyl)amino]phenoxy]benzene-1,2-dicarboxylate Chemical compound C1=C(C(=O)OC)C(C(=O)OC)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC=CC=C1F FOEMSVVLOJVPQA-UHFFFAOYSA-N 0.000 claims description 2
- OVDUANNCKBGWQN-UHFFFAOYSA-N dimethyl 4-[2-[(3-acetylbenzoyl)amino]phenoxy]benzene-1,2-dicarboxylate Chemical compound C1=C(C(=O)OC)C(C(=O)OC)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC=CC(C(C)=O)=C1 OVDUANNCKBGWQN-UHFFFAOYSA-N 0.000 claims description 2
- OTGHWRBMKUJNAF-UHFFFAOYSA-N dimethyl 4-[2-[(3-aminobenzoyl)amino]phenoxy]benzene-1,2-dicarboxylate Chemical compound C1=C(C(=O)OC)C(C(=O)OC)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC=CC(N)=C1 OTGHWRBMKUJNAF-UHFFFAOYSA-N 0.000 claims description 2
- NFPQLJCRDAFOPP-UHFFFAOYSA-N dimethyl 4-[2-[(3-bromobenzoyl)amino]phenoxy]benzene-1,2-dicarboxylate Chemical compound C1=C(C(=O)OC)C(C(=O)OC)=CC=C1OC1=CC=CC=C1NC(=O)C1=CC=CC(Br)=C1 NFPQLJCRDAFOPP-UHFFFAOYSA-N 0.000 claims description 2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200201630 | 2002-10-28 | ||
| US10/429,625 US20040082641A1 (en) | 2002-10-28 | 2003-05-05 | Use of glycogen phosphorylase inhibitors for treatment of cardiovascular diseases |
| US10/429,626 US6960610B2 (en) | 2002-10-28 | 2003-05-05 | Use of glycogen phosphorylase inhibitors for treatment of cardiovascular diseases |
| PCT/DK2003/000695 WO2004037233A2 (en) | 2002-10-28 | 2003-10-14 | Use of glycogen phosphorylase inhibitors for treatment of cardiovascular diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006507359A true JP2006507359A (ja) | 2006-03-02 |
| JP2006507359A5 JP2006507359A5 (https=) | 2006-11-30 |
Family
ID=32180137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005501508A Withdrawn JP2006507359A (ja) | 2002-10-28 | 2003-10-14 | 心循環器疾患の治療のためのグリコーゲンホスホリラーゼ阻害剤の使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20050054618A1 (https=) |
| EP (1) | EP1558245A2 (https=) |
| JP (1) | JP2006507359A (https=) |
| AU (1) | AU2003273762A1 (https=) |
| WO (1) | WO2004037233A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013508366A (ja) * | 2009-10-19 | 2013-03-07 | アミカス セラピューティックス インコーポレイテッド | 中枢神経系の変性障害を予防および／または治療するための新規の組成物 |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| BRPI1015472A2 (pt) * | 2009-04-09 | 2015-11-24 | Amicus Therapeutics Inc | métodos para prevenção e/ou tratamento de doenças degenerativas do sistema nervoso central |
| BRPI1010517A2 (pt) * | 2009-04-09 | 2017-01-31 | Amicus Therapeutics Inc | métodos para prevenção e/ou tratamento de doenças de armazenamento lisossomal |
| SI2995306T1 (sl) | 2009-10-19 | 2019-04-30 | Amicus Therapeutics, Inc. | Novi sestavki za preprečevanje in/ali zdravljenje motenj lizosomskega shranjevanja |
| ES2526675T3 (es) | 2010-07-09 | 2015-01-14 | Pfizer Limited | N-sulfonilbenzamidas como inhibidores de los canales de sodio dependientes de voltaje |
| CA2804593C (en) | 2010-07-09 | 2015-11-24 | Pfizer Limited | Biphenyloxybenzensulphonamide derivatives useful as sodium channel inhibitors |
| US20220184185A1 (en) | 2018-07-25 | 2022-06-16 | Modernatx, Inc. | Mrna based enzyme replacement therapy combined with a pharmacological chaperone for the treatment of lysosomal storage disorders |
| CA3141826A1 (en) | 2019-05-31 | 2020-12-03 | Ikena Oncology, Inc. | Tead inhibitors and uses thereof |
| CA3142351A1 (en) | 2019-05-31 | 2020-12-03 | Ikena Oncology, Inc. | Tead inhibitors and uses thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5338829A (en) * | 1988-04-20 | 1994-08-16 | Trustees Of The University Of Pennsylvania | Peptides derived from human immunodeficiency virus-1 GP160 |
| US5242687A (en) * | 1989-03-15 | 1993-09-07 | Tkb Associates Limited Partnership | Method of reducing cellular immune response involving T-cells using CD8-bearing antigen presenting cells |
| US5759551A (en) * | 1993-04-27 | 1998-06-02 | United Biomedical, Inc. | Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines |
| US5705388A (en) * | 1994-12-23 | 1998-01-06 | Ribozyme Pharmaceuticals, Inc. | CETP Ribozymes |
| CZ120398A3 (cs) * | 1995-09-08 | 1998-12-16 | Novo Nordisk A/S | Použití 2-alkylpyrrolidinových derivátů pro přípravu léčiva pro léčbu diabetu, 2-alkylpyrrolidiné deriváty |
| US5998463A (en) * | 1998-02-27 | 1999-12-07 | Pfizer Inc | Glycogen phosphorylase inhibitors |
| JP2002536410A (ja) * | 1999-02-12 | 2002-10-29 | ノボ ノルディスク アクティーゼルスカブ | 肥満の治療又は予防もしくは食欲の調節を目的とした薬学的組成物の製造におけるピロリジン誘導体の使用 |
-
2003
- 2003-10-14 EP EP03757718A patent/EP1558245A2/en not_active Withdrawn
- 2003-10-14 JP JP2005501508A patent/JP2006507359A/ja not_active Withdrawn
- 2003-10-14 AU AU2003273762A patent/AU2003273762A1/en not_active Abandoned
- 2003-10-14 WO PCT/DK2003/000695 patent/WO2004037233A2/en not_active Ceased
-
2004
- 2004-09-17 US US10/943,548 patent/US20050054618A1/en not_active Abandoned
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013508366A (ja) * | 2009-10-19 | 2013-03-07 | アミカス セラピューティックス インコーポレイテッド | 中枢神経系の変性障害を予防および／または治療するための新規の組成物 |
| JP2015157822A (ja) * | 2009-10-19 | 2015-09-03 | アミカス セラピューティックス インコーポレイテッド | 中枢神経系の変性障害を予防および／または治療するための新規の組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004037233A3 (en) | 2004-07-29 |
| AU2003273762A8 (en) | 2004-05-13 |
| EP1558245A2 (en) | 2005-08-03 |
| WO2004037233A2 (en) | 2004-05-06 |
| AU2003273762A1 (en) | 2004-05-13 |
| US20050054618A1 (en) | 2005-03-10 |
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