JP2006506071A5 - - Google Patents

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Publication number
JP2006506071A5
JP2006506071A5 JP2004552160A JP2004552160A JP2006506071A5 JP 2006506071 A5 JP2006506071 A5 JP 2006506071A5 JP 2004552160 A JP2004552160 A JP 2004552160A JP 2004552160 A JP2004552160 A JP 2004552160A JP 2006506071 A5 JP2006506071 A5 JP 2006506071A5
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JP
Japan
Prior art keywords
cancer
pipa
tumor
antibody
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2004552160A
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English (en)
Japanese (ja)
Other versions
JP4757493B2 (ja
JP2006506071A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2003/036134 external-priority patent/WO2004043239A2/en
Publication of JP2006506071A publication Critical patent/JP2006506071A/ja
Publication of JP2006506071A5 publication Critical patent/JP2006506071A5/ja
Application granted granted Critical
Publication of JP4757493B2 publication Critical patent/JP4757493B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2004552160A 2002-11-13 2003-11-13 抗原ｐｉｐａおよびそれに結合する抗体 Expired - Fee Related JP4757493B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42619202P 2002-11-13 2002-11-13
US60/426,192 2002-11-13
PCT/US2003/036134 WO2004043239A2 (en) 2002-11-13 2003-11-13 Antigen pipa and antibodies that bind thereto

Publications (3)

Publication Number Publication Date
JP2006506071A JP2006506071A (ja) 2006-02-23
JP2006506071A5 true JP2006506071A5 (https=) 2007-01-11
JP4757493B2 JP4757493B2 (ja) 2011-08-24

Family

ID=32313118

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004552160A Expired - Fee Related JP4757493B2 (ja) 2002-11-13 2003-11-13 抗原ｐｉｐａおよびそれに結合する抗体

Country Status (6)

Country Link
US (1) US7405061B2 (https=)
EP (1) EP1581096A4 (https=)
JP (1) JP4757493B2 (https=)
AU (1) AU2003295474B2 (https=)
CA (1) CA2505633A1 (https=)
WO (1) WO2004043239A2 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
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US8574623B2 (en) 2004-12-22 2013-11-05 Nitto Denko Corporation Therapeutic agent for pulmonary fibrosis
US8652526B2 (en) 2004-12-22 2014-02-18 Nitto Denko Corporation Drug carrier and drug carrier kit for inhibiting fibrosis
US8686052B2 (en) 2007-03-30 2014-04-01 Nitto Denko Corporation Targeting agent for cancer cell or cancer-associated fibroblast

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004043239A2 (en) 2002-11-13 2004-05-27 Raven Biotechnologies, Inc. Antigen pipa and antibodies that bind thereto
AU2006210589B2 (en) 2005-02-02 2011-12-08 Macrogenics West, Inc. ADAM-9 modulators
US9572886B2 (en) 2005-12-22 2017-02-21 Nitto Denko Corporation Agent for treating myelofibrosis
EP2376109B1 (en) 2008-12-19 2019-01-23 MacroGenics, Inc. Covalent diabodies and uses thereof
JP5998060B2 (ja) 2010-03-04 2016-09-28 マクロジェニクス，インコーポレーテッド Ｂ７−ｈ３と反応性のある抗体、その免疫学的に活性なフラグメントおよびその使用
EP2601216B1 (en) 2010-08-02 2018-01-03 MacroGenics, Inc. Covalent diabodies and uses thereof
CA2836873C (en) 2011-05-21 2019-10-22 Macrogenics, Inc. Deimmunized serum-binding domains and their use for extending serum half-life
RU2639459C2 (ru) 2011-06-21 2017-12-21 Нитто Денко Корпорейшн Апоптоз-индуцирующее средство
JP6340162B2 (ja) 2012-12-20 2018-06-06 日東電工株式会社 アポトーシス誘導剤
JP6076076B2 (ja) 2012-12-21 2017-02-08 日東電工株式会社 組織再生促進剤
EP3152235B1 (en) 2014-05-29 2021-08-25 MacroGenics, Inc. Tri-specific binding molecules and methods of use thereof
JP6727765B2 (ja) 2014-06-17 2020-07-22 日東電工株式会社 アポトーシス誘導剤
WO2017019846A1 (en) 2015-07-30 2017-02-02 Macrogenics, Inc. Pd-1-binding molecules and methods use thereof
US10954301B2 (en) 2015-12-14 2021-03-23 Macrogenics, Inc. Bispecific molecules having immunoreactivity with PD-1 and CTLA-4, and methods of use thereof
IL268836B2 (en) 2017-02-24 2024-04-01 Macrogenics Inc Bispecific binding molecules that are capable of binding cd137 and tumor antigens, and uses thereof
SG11202005557TA (en) 2017-12-12 2020-07-29 Macrogenics Inc Bispecific cd 16-binding molecules and their use in the treatment of disease
SG11202007572VA (en) 2018-02-15 2020-09-29 Macrogenics Inc Variant cd3-binding domains and their use in combination therapies for the treatment of disease

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US6054561A (en) * 1984-02-08 2000-04-25 Chiron Corporation Antigen-binding sites of antibody molecules specific for cancer antigens
US5807715A (en) * 1984-08-27 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
US4676980A (en) * 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
US5496550A (en) * 1986-08-14 1996-03-05 Chilwalner Method of reducing the output of Eimeria oocysts from a newborn chick
EP0299242A3 (en) * 1987-06-22 1989-01-25 Medico Labs Ag Heterologous viral peptide particle immunogens
US5677425A (en) * 1987-09-04 1997-10-14 Celltech Therapeutics Limited Recombinant antibody
GB8928874D0 (en) * 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
US5552391A (en) * 1990-01-16 1996-09-03 La Jolla Pharmaceutical Company Chemically-defined non-polymeric valency platform molecules and conjugates thereof
US5427908A (en) * 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
EP0519596B1 (en) 1991-05-17 2005-02-23 Merck & Co. Inc. A method for reducing the immunogenicity of antibody variable domains
WO1994004679A1 (en) * 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
GB9115364D0 (en) * 1991-07-16 1991-08-28 Wellcome Found Antibody
AU669124B2 (en) * 1991-09-18 1996-05-30 Kyowa Hakko Kirin Co., Ltd. Process for producing humanized chimera antibody
ES2136092T3 (es) * 1991-09-23 1999-11-16 Medical Res Council Procedimientos para la produccion de anticuerpos humanizados.
US5733743A (en) * 1992-03-24 1998-03-31 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
JP3919830B2 (ja) * 1992-11-28 2007-05-30 財団法人化学及血清療法研究所 抗ネコヘルペスウイルス−１組換え抗体および該抗体をコードする遺伝子断片
DE69333627T2 (de) * 1993-01-14 2005-09-22 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Rekombinanter anti-hiv antikörper und seine herstellung
US6180377B1 (en) * 1993-06-16 2001-01-30 Celltech Therapeutics Limited Humanized antibodies
US5665570A (en) * 1994-02-10 1997-09-09 Takeda Chemical Industries, Ltd. Antibody-encoding recombinant DNA and its use
US5532159A (en) * 1994-04-01 1996-07-02 The Ohio State University Monoclonal antibody to canine placental oncofetal protein for detecting cancer
US6265150B1 (en) * 1995-06-07 2001-07-24 Becton Dickinson & Company Phage antibodies
AU2077197A (en) * 1996-03-18 1997-10-10 Novo Nordisk Biotech, Inc. Polypeptides having phytase activity and nucleic acids encoding same
CA2249998A1 (en) * 1996-03-27 1997-10-02 Crc For Biopharmaceutical Research Pty. Ltd. The use of antibodies against cd48 for the treatment of t and b cell lymphomas and leukemias
ID20581A (id) 1996-10-18 1999-01-21 Res Fnd For Micbial Diseases O Antigen rotavirus, vaksin dan agen diagnostik untuk infeksi rotavirus, serta metode untuk menghasilkan antigen
DE29803477U1 (de) * 1998-03-03 1998-07-09 P.E.R. Flucht- und Rettungsleitsysteme GmbH, 22885 Barsbüttel Vorrichtung zur Ausbildung aktiv leuchtender Leuchtwegesysteme
US6406840B1 (en) * 1999-12-17 2002-06-18 Biomosaic Systems, Inc. Cell arrays and the uses thereof
US6416999B1 (en) * 2000-04-07 2002-07-09 Raven Biotechnologies, Inc. Human Müllerian duct-derived epithelial cells and methods of isolation and uses thereof
US6441163B1 (en) * 2001-05-31 2002-08-27 Immunogen, Inc. Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents
WO2004043239A2 (en) 2002-11-13 2004-05-27 Raven Biotechnologies, Inc. Antigen pipa and antibodies that bind thereto

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8574623B2 (en) 2004-12-22 2013-11-05 Nitto Denko Corporation Therapeutic agent for pulmonary fibrosis
US8652526B2 (en) 2004-12-22 2014-02-18 Nitto Denko Corporation Drug carrier and drug carrier kit for inhibiting fibrosis
US8686052B2 (en) 2007-03-30 2014-04-01 Nitto Denko Corporation Targeting agent for cancer cell or cancer-associated fibroblast

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