JP2006506071A5 - - Google Patents
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- Publication number
- JP2006506071A5 JP2006506071A5 JP2004552160A JP2004552160A JP2006506071A5 JP 2006506071 A5 JP2006506071 A5 JP 2006506071A5 JP 2004552160 A JP2004552160 A JP 2004552160A JP 2004552160 A JP2004552160 A JP 2004552160A JP 2006506071 A5 JP2006506071 A5 JP 2006506071A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- pipa
- tumor
- antibody
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42619202P | 2002-11-13 | 2002-11-13 | |
| US60/426,192 | 2002-11-13 | ||
| PCT/US2003/036134 WO2004043239A2 (en) | 2002-11-13 | 2003-11-13 | Antigen pipa and antibodies that bind thereto |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006506071A JP2006506071A (ja) | 2006-02-23 |
| JP2006506071A5 true JP2006506071A5 (enExample) | 2007-01-11 |
| JP4757493B2 JP4757493B2 (ja) | 2011-08-24 |
Family
ID=32313118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004552160A Expired - Fee Related JP4757493B2 (ja) | 2002-11-13 | 2003-11-13 | 抗原pipaおよびそれに結合する抗体 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7405061B2 (enExample) |
| EP (1) | EP1581096A4 (enExample) |
| JP (1) | JP4757493B2 (enExample) |
| AU (1) | AU2003295474B2 (enExample) |
| CA (1) | CA2505633A1 (enExample) |
| WO (1) | WO2004043239A2 (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8574623B2 (en) | 2004-12-22 | 2013-11-05 | Nitto Denko Corporation | Therapeutic agent for pulmonary fibrosis |
| US8652526B2 (en) | 2004-12-22 | 2014-02-18 | Nitto Denko Corporation | Drug carrier and drug carrier kit for inhibiting fibrosis |
| US8686052B2 (en) | 2007-03-30 | 2014-04-01 | Nitto Denko Corporation | Targeting agent for cancer cell or cancer-associated fibroblast |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2505633A1 (en) | 2002-11-13 | 2004-05-27 | Raven Biotechnologies, Inc. | Antigen pipa and antibodies that bind thereto |
| AU2006210589B2 (en) | 2005-02-02 | 2011-12-08 | Macrogenics West, Inc. | ADAM-9 modulators |
| WO2010080538A1 (en) | 2008-12-19 | 2010-07-15 | Macrogenics, Inc. | Covalent diabodies and uses thereof |
| US9572886B2 (en) | 2005-12-22 | 2017-02-21 | Nitto Denko Corporation | Agent for treating myelofibrosis |
| PH12018501083A1 (en) | 2010-03-04 | 2019-02-18 | Macrogenics Inc | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| MX339622B (es) | 2010-08-02 | 2016-06-02 | Macrogenics Inc | Diacuerpos covalentes y sus usos. |
| EP2714079B2 (en) | 2011-05-21 | 2019-08-28 | MacroGenics, Inc. | Deimmunized serum-binding domains and their use for extending serum half-life |
| EP2724729B1 (en) | 2011-06-21 | 2018-12-26 | Nitto Denko Corporation | Apoptosis-inducing agent |
| JP6340162B2 (ja) | 2012-12-20 | 2018-06-06 | 日東電工株式会社 | アポトーシス誘導剤 |
| JP6076076B2 (ja) | 2012-12-21 | 2017-02-08 | 日東電工株式会社 | 組織再生促進剤 |
| EP3152235B1 (en) | 2014-05-29 | 2021-08-25 | MacroGenics, Inc. | Tri-specific binding molecules and methods of use thereof |
| JP6727765B2 (ja) | 2014-06-17 | 2020-07-22 | 日東電工株式会社 | アポトーシス誘導剤 |
| SMT202100527T1 (it) | 2015-07-30 | 2021-11-12 | Macrogenics Inc | Molecole di legame a pd-1 e lag-3 e loro metodi d'uso |
| SG11201804839WA (en) | 2015-12-14 | 2018-07-30 | Macrogenics Inc | Bispecific molecules having immunoreactivity with pd-1 and ctla-4, and methods of use thereof |
| US11459394B2 (en) | 2017-02-24 | 2022-10-04 | Macrogenics, Inc. | Bispecific binding molecules that are capable of binding CD137 and tumor antigens, and uses thereof |
| SG11202005557TA (en) | 2017-12-12 | 2020-07-29 | Macrogenics Inc | Bispecific cd 16-binding molecules and their use in the treatment of disease |
| CN111787949A (zh) | 2018-02-15 | 2020-10-16 | 宏观基因有限公司 | 变体cd3-结合结构域及其在用于治疗疾病的组合疗法中的用途 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US6054561A (en) | 1984-02-08 | 2000-04-25 | Chiron Corporation | Antigen-binding sites of antibody molecules specific for cancer antigens |
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
| US5496550A (en) | 1986-08-14 | 1996-03-05 | Chilwalner | Method of reducing the output of Eimeria oocysts from a newborn chick |
| ATE207535T1 (de) | 1987-06-22 | 2001-11-15 | Medeva Holdings Bv | Hepatitis-b-oberflächenantigen enthaltendes peptid |
| US5677425A (en) | 1987-09-04 | 1997-10-14 | Celltech Therapeutics Limited | Recombinant antibody |
| GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| US5552391A (en) | 1990-01-16 | 1996-09-03 | La Jolla Pharmaceutical Company | Chemically-defined non-polymeric valency platform molecules and conjugates thereof |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| DE69233482T2 (de) | 1991-05-17 | 2006-01-12 | Merck & Co., Inc. | Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| GB9115364D0 (en) | 1991-07-16 | 1991-08-28 | Wellcome Found | Antibody |
| AU669124B2 (en) | 1991-09-18 | 1996-05-30 | Kyowa Hakko Kirin Co., Ltd. | Process for producing humanized chimera antibody |
| US5565332A (en) | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
| US5733743A (en) | 1992-03-24 | 1998-03-31 | Cambridge Antibody Technology Limited | Methods for producing members of specific binding pairs |
| JP3919830B2 (ja) | 1992-11-28 | 2007-05-30 | 財団法人化学及血清療法研究所 | 抗ネコヘルペスウイルス−1組換え抗体および該抗体をコードする遺伝子断片 |
| WO1994015969A1 (fr) | 1993-01-14 | 1994-07-21 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Anticorps anti-vih recombine et sa preparation |
| US6180377B1 (en) | 1993-06-16 | 2001-01-30 | Celltech Therapeutics Limited | Humanized antibodies |
| US5665570A (en) | 1994-02-10 | 1997-09-09 | Takeda Chemical Industries, Ltd. | Antibody-encoding recombinant DNA and its use |
| US5532159A (en) | 1994-04-01 | 1996-07-02 | The Ohio State University | Monoclonal antibody to canine placental oncofetal protein for detecting cancer |
| US6265150B1 (en) | 1995-06-07 | 2001-07-24 | Becton Dickinson & Company | Phage antibodies |
| WO1997035016A1 (en) | 1996-03-18 | 1997-09-25 | Novo Nordisk Biotech Inc | Polypeptides having phytase activity and nucleic acids encoding same |
| CA2249998A1 (en) * | 1996-03-27 | 1997-10-02 | Crc For Biopharmaceutical Research Pty. Ltd. | The use of antibodies against cd48 for the treatment of t and b cell lymphomas and leukemias |
| WO1998017785A1 (en) | 1996-10-18 | 1998-04-30 | The Research Foundation For Microbial Diseases Of Osaka University | Rotavirus antigens, vaccines and diagnostic drugs for infection with rotavirus, and processes for producing the same |
| DE29803477U1 (de) * | 1998-03-03 | 1998-07-09 | P.E.R. Flucht- und Rettungsleitsysteme GmbH, 22885 Barsbüttel | Vorrichtung zur Ausbildung aktiv leuchtender Leuchtwegesysteme |
| US6406840B1 (en) | 1999-12-17 | 2002-06-18 | Biomosaic Systems, Inc. | Cell arrays and the uses thereof |
| US6416999B1 (en) | 2000-04-07 | 2002-07-09 | Raven Biotechnologies, Inc. | Human Müllerian duct-derived epithelial cells and methods of isolation and uses thereof |
| US6441163B1 (en) | 2001-05-31 | 2002-08-27 | Immunogen, Inc. | Methods for preparation of cytotoxic conjugates of maytansinoids and cell binding agents |
| CA2505633A1 (en) | 2002-11-13 | 2004-05-27 | Raven Biotechnologies, Inc. | Antigen pipa and antibodies that bind thereto |
-
2003
- 2003-11-13 CA CA002505633A patent/CA2505633A1/en not_active Abandoned
- 2003-11-13 AU AU2003295474A patent/AU2003295474B2/en not_active Ceased
- 2003-11-13 JP JP2004552160A patent/JP4757493B2/ja not_active Expired - Fee Related
- 2003-11-13 US US10/713,248 patent/US7405061B2/en not_active Expired - Fee Related
- 2003-11-13 WO PCT/US2003/036134 patent/WO2004043239A2/en not_active Ceased
- 2003-11-13 EP EP03786664A patent/EP1581096A4/en not_active Withdrawn
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8574623B2 (en) | 2004-12-22 | 2013-11-05 | Nitto Denko Corporation | Therapeutic agent for pulmonary fibrosis |
| US8652526B2 (en) | 2004-12-22 | 2014-02-18 | Nitto Denko Corporation | Drug carrier and drug carrier kit for inhibiting fibrosis |
| US8686052B2 (en) | 2007-03-30 | 2014-04-01 | Nitto Denko Corporation | Targeting agent for cancer cell or cancer-associated fibroblast |
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