JP2006505331A - 半人工椎間円板交換システム - Google Patents
半人工椎間円板交換システム Download PDFInfo
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- A—HUMAN NECESSITIES
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/442—Intervertebral or spinal discs, e.g. resilient
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- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
- A61F2/4603—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
- A61F2/4611—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof of spinal prostheses
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2002/2817—Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
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- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2002/2835—Bone graft implants for filling a bony defect or an endoprosthesis cavity, e.g. by synthetic material or biological material
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/3006—Properties of materials and coating materials
- A61F2002/30075—Properties of materials and coating materials swellable, e.g. when wetted
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/442—Intervertebral or spinal discs, e.g. resilient
- A61F2002/444—Intervertebral or spinal discs, e.g. resilient for replacing the nucleus pulposus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2002/4495—Joints for the spine, e.g. vertebrae, spinal discs having a fabric structure, e.g. made from wires or fibres
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
- A61F2/4603—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
- A61F2002/4625—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use
- A61F2002/4627—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use with linear motion along or rotating motion about the instrument axis or the implantation direction, e.g. telescopic, along a guiding rod, screwing inside the instrument
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0061—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof swellable
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Abstract
Description
Claims (52)
- 脊椎動物の脊柱変性円板症のための半人工核体交換システムであって、
孔部を形成するために少なくとも部分的に穿孔されている変性円板内に提供された小挿入孔に対応する小径を有する注入管と、
前記孔部の少なくとも1部を埋める量の組織成長促進物質と、
該組織成長促進物質を少しづつ前記孔部へ注入するために前記注入管に操作可能にカップリングされた挿入装置と、
を含んでいることを特徴とするシステム。 - 組織促進物質は線維組織成長促進物質、軟骨成長促進物質及びこれらの組み合わせから成る群から選択されることを特徴とする請求項1記載の核体交換システム。
- 組織成長促進物質は円形に積層された複層帯体であることを特徴とする請求項1記載の核体交換システム。
- 組織成長促進物質は絡合形態であることを特徴とする請求項1記載の核体交換システム。
- 組織成長促進物質は複数の線維帯体であることを特徴とする請求項1記載の核体交換システム。
- 組織成長促進物質はヒドロゲルとの組み合わせ体であることを特徴とする請求項1記載の核交換システム。
- 組織成長促進物質は孔質コンテナに収容されていることを特徴とする請求項1記載の核交換システム。
- 組織成長促進物質は筋膜の自家移植片、同種移植片あるいは異種移植片、人工ポリマー線維、タルク、組織成長促進薬剤、組織成長促進鉱物、組織形態発生蛋白質、脊索細胞及びこれらの組み合わせから成る群から選択されることを特徴とする請求項1記載の核体交換システム。
- 脊椎動物の脊柱変性円板症のための半人工核体交換システムであって、
孔部を形成するために少なくとも部分的に穿孔されている変性円板内に提供された小挿入孔に対応する小径を有する注入管と、
前記孔部の少なくとも1部を埋める量のヒドロゲルストランド体と組み合わされた組織成長促進物質のストランド体と、
該ヒドロゲルストランド体と組み合わされた組織成長促進物質のストランド体を少しづつ前記孔部へ注入するために前記注入管に操作可能にカップリングされた挿入装置と、
を含んでいることを特徴とするシステム。 - 組織成長促進物質は線維組織成長促進物質、軟骨成長促進物質及びこれらの組み合わせから成る群から選択されることを特徴とする請求項9記載の客体交換システム。
- 組織成長促進物質は円形に積層された複層帯体であることを特徴とする請求項9記載の核体交換システム。
- 組織成長促進物質は絡合形態であることを特徴とする請求項9記載の核体交換システム。
- 組織成長促進物質は複数の線維帯体であることを特徴とする請求項9記載の核体交換システム。
- 組織成長促進物質は孔質コンテナに収容されていることを特徴とする請求項9記載の核体交換システム。
- 組織成長促進物質は筋膜の自家移植片、同種移植片あるいは異種移植片、自家移植片、人工ポリマー線維、タルク、組織成長促進薬剤、組織成長促進鉱物、組織形態発生蛋白質、脊索細胞及びこれらの組み合わせから成る群から選択されることを特徴とする請求項9記載の核体交換システム。
- 脊椎動物の脊柱変性円板症のための半人工核体交換システムであって、
孔部を形成するために少なくとも部分的に穿孔されている変性円板内に提供された小挿入孔に対応する小径を有する注入管と、
該注入管の径より小さい径の断面を有する少なくとも1つの柔軟な組織成長促進物質のストランド体と、
前記孔部の少なくとも1部を埋める量の前記少なくとも1つの柔軟な組織成長促進物質のストランド体と、
少なくとも1つの該ストランド体が前記孔部の少なくとも1部を埋めるべく折り畳まれるように、前記柔軟な組織成長促進物質を前記孔部に注入する前記注入管に操作可能にカップリングされた挿入装置と、
を含んでいることを特徴とするシステム。 - 組織成長促進物質は線維組織成長促進物質、軟骨成長促進物質及びこれらの組み合わせから成る群から選択されることを特徴とする請求項1記載の核体交換システム。
- 組織成長促進物質は円形に積層された複層帯体であることを特徴とする請求項16記載のシステム。
- 組織成長促進物質は絡合形態であることを特徴とする請求項16記載の核体交換システム。
- 組織成長促進物質は複数の線維帯体であることを特徴とする請求項16記載の核体交換システム。
- 組織成長促進物質はヒドロゲルとの組み合わせ体であることを特徴とする請求項16記載の核体交換システム。
- 組織成長促進物質は孔質コンテナに収容されていることを特徴とする請求項16記載の核体交換システム。
- 組織成長促進物質は、筋膜の自家移植片、同種移植片あるいは異種移植片、自家移植片、人工ポリマー線維、タルク、組織成長促進薬剤、組織成長促進鉱物、組織形態発生蛋白質、脊索細胞及びこれらの組み合わせから成る群から選択されることを特徴とする請求項16記載の核体交換システム。
- 脊椎動物の脊柱変性円板症のための半人工核体交換方法であって、
変性円板に小挿入孔を設けるステップと、
前記変性円板に孔部を設け、前記小挿入孔を介して少なくとも1部の変性円板核体を除去するステップと、
組織成長促進物質に対する脊椎動物の組織形成反応を刺激して変性円板の半人工核体交換体を創出するために、複数の組織成長促進物質片を前記孔部に挿入するステップと、
を含んでいることを特徴とする方法。 - 組織成長促進物質は、線維組織成長促進物質、軟骨成長促進物質及びこれらの組み合わせから成る群から選択されることを特徴とする請求項24記載の方法。
- エンドプレート軟骨は部分的に除去されることを特徴とする請求項24記載の方法。
- エンドプレート軟骨は保持されることを特徴とする請求項24記載の方法。
- 外環部は部分的に除去されることを特徴とする請求項24記載の方法。
- 外環部は部分的に保持されることを特徴とする請求項24記載の方法。
- 組織成長促進物質は筋膜の自家移植片、同種移植片あるいは異種移植片、人工ポリマー線維、タルク、組織成長促進薬剤、組織成長促進鉱物、組織形態発生蛋白質、脊索細胞及びこれらの組み合わせから成る群から選択されることを特徴とする請求項24記載の方法。
- 円板孔部表面は組織成長促進物質でコーティングされていることを特徴とする請求項24記載の方法。
- 組織成長促進物質はヒドロゲルとの組み合わせ体であることを特徴とする請求項24記載の方法。
- 円板孔部に孔質コンテナを挿入するステップをさらに含んでおり、
前記孔質コンテナは組織成長促進物質の挿入用に設計されていることを特徴とする請求項24記載の方法。 - 脊椎動物の脊柱変性円板症のための半人工核体交換方法であって、
変性円板に小挿入孔を設けるステップと、
前記変性円板に孔部を設け、前記小挿入孔を介して少なくとも部分的に変性円板核体を除去するステップと、
組織成長促進物質に対する脊椎動物の組織形成反応を刺激して変性円板の半人工核体交換体を創出すべく、少なくとも1つのストランド体を前記孔部内で折り畳むように、少なくとも1つの柔軟な組織成長促進物質のストランド体を前記孔部に挿入するステップと、
を含んでいることを特徴とする方法。 - 組織成長促進物質は線維組織成長促進物質、軟骨成長促進物質及びこれらの組み合わせから成る群から選択されることを特徴とする請求項34記載の方法。
- エンドプレート軟骨は部分的に除去されることを特徴とする請求項34記載の方法。
- エンドプレート軟骨は保持されることを特徴とする請求項34記載の方法。
- 外環部は部分的に除去されることを特徴とする請求項34記載の方法。
- 外環部は保持されることを特徴とする請求項34記載の方法。
- 組織成長促進物質は太腿筋膜の自家移植片、同種移植片あるいは異種移植片、自家移植片、人工ポリマー線維、タルク、組織成長促進薬剤、組織成長促進鉱物、組織形態発生蛋白質、脊索細胞及びこれらの組み合わせから成る群から選択されることを特徴とする請求項34記載の方法。
- 円板孔部表面は組織成長促進物質でコーティングされていることを特徴とする請求項34記載の方法。
- 組織成長促進物質はヒドロゲルとの組み合わせ体であることを特徴とする請求項34記載の方法。
- 円板孔部に孔質コンテナを挿入するステップをさらに含んでおり、
前記孔質コンテナは組織成長促進物質の挿入用に設計されていることを特徴とする請求項34記載の方法。 - 脊椎動物の脊柱変性円板症のための半人工核体交換方法であって、
変性円板に小挿入孔を設けるステップと、
前記変性円板に孔部を設け、前記小挿入孔を介して少なくとも部分的に変性円板核体を除去するステップと、
組織成長促進物質に対する脊椎動物の組織形成反応を刺激して変性円板の半人工核体交換体を創出するために、複数のヒドロゲル片と組み合わされた複数の組織成長促進物質片を前記孔部に挿入するステップと、
を含んでいることを特徴とする方法。 - 組織成長促進物質は、線維組織成長促進物質、軟骨成長促進物質及びこれらの組み合わせから成る群から選択されることを特徴とする請求項44記載の方法。
- エンドプレート軟骨は部分的に除去されることを特徴とする請求項44記載の方法。
- エンドプレート軟骨は保持されることを特徴とする請求項44記載の方法。
- 外環部は部分的に除去されることを特徴とする請求項44記載の方法。
- 外環部は保持されることを特徴とする請求項44記載の方法。
- 組織成長促進物質は大腿筋膜の自家移植片、同種移植片あるいは異種移植片、自家移植片、人工ポリマー線維、タルク、組織成長促進薬剤、組織成長促進鉱物、組織形態発生蛋白質、脊索細胞及びこれらの組み合わせから成る群から選択されることを特徴とする請求項44記載の方法。
- 円板孔部表面は組織成長促進物質でコーティングされていることを特徴とする請求項44記載の方法。
- 円板孔部に孔質コンテナを挿入するステップをさらに含んでおり、
前記孔質コンテナは組織成長促進物質の挿入用に設計されていることを特徴とする請求項44記載の方法。
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WO2004041075A2 (en) | 2004-05-21 |
AU2003290627A1 (en) | 2004-06-07 |
CA2735334A1 (en) | 2004-05-21 |
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