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US20030028251A1 - Methods and devices for interbody spinal stabilization - Google Patents

Methods and devices for interbody spinal stabilization Download PDF

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Publication number
US20030028251A1
US20030028251A1 US09918332 US91833201A US2003028251A1 US 20030028251 A1 US20030028251 A1 US 20030028251A1 US 09918332 US09918332 US 09918332 US 91833201 A US91833201 A US 91833201A US 2003028251 A1 US2003028251 A1 US 2003028251A1
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Prior art keywords
space
disc
portion
material
distractor
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Abandoned
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US09918332
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Hallett Mathews
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Warsaw Orthopedic Inc
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SDGI Holdings Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/885Tools for expanding or compacting bones or discs or cavities therein
    • A61B17/8852Tools for expanding or compacting bones or discs or cavities therein capable of being assembled or enlarged, or changing shape, inside the bone or disc
    • A61B17/8855Tools for expanding or compacting bones or discs or cavities therein capable of being assembled or enlarged, or changing shape, inside the bone or disc inflatable, e.g. kyphoplasty balloons
    • AHUMAN NECESSITIES
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    • A61B17/025Joint distractors
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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
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    • A61F2/4603Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
    • A61F2/4611Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof of spinal prostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters
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    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/8802Equipment for handling bone cement or other fluid fillers
    • A61B17/8805Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it
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    • A61B17/00234Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00238Type of minimally invasive operation
    • A61B2017/00243Type of minimally invasive operation cardiac
    • AHUMAN NECESSITIES
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    • A61B2017/00238Type of minimally invasive operation
    • A61B2017/00261Discectomy
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    • A61B2017/00535Surgical instruments, devices or methods, e.g. tourniquets pneumatically or hydraulically operated
    • A61B2017/00557Surgical instruments, devices or methods, e.g. tourniquets pneumatically or hydraulically operated inflatable
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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2/4455Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2/46Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4601Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for introducing bone substitute, for implanting bone graft implants or for compacting them in the bone cavity
    • AHUMAN NECESSITIES
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    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2817Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2835Bone graft implants for filling a bony defect or an endoprosthesis cavity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/30004The prosthesis made from materials having different values of a given property at different locations within the same prosthesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442Intervertebral or spinal discs, e.g. resilient
    • A61F2002/444Intervertebral or spinal discs, e.g. resilient for replacing the nucleus pulposus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4603Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof
    • A61F2002/4625Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use
    • A61F2002/4627Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor for insertion or extraction of endoprosthetic joints or of accessories thereof with relative movement between parts of the instrument during use with linear motion along or rotating motion about the instrument axis or the implantation direction, e.g. telescopic, along a guiding rod, screwing inside the instrument
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00353Bone cement, e.g. polymethylmethacrylate or PMMA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/02Bones

Abstract

Methods and instruments for preparing a disc space and for forming interbody devices therein are provided. The instruments include distractors having enlargeable portions positionable in the disc space for distracting the disc space. The enlargeable portions can also provide form about or against which an interbody device of a first material is placed. A second material may be placed in the disc space in the space previously occupied by the distractors.

Description

    FIELD OF THE INVENTION
  • [0001]
    The present invention relates generally to instruments and devices for spinal surgery, more particularly to methods and devices for spinal disc space preparation and interbody spinal stabilization.
  • BACKGROUND OF THE INVENTION
  • [0002]
    There are prior art interbody devices that are fabricated prior to implantation and then inserted into the patient's spinal disc space during surgery. It is also known to insert one or more pre-fabricated devices from anterior, antero-lateral, lateral, postero-lateral, transforaminal, posterior, posterior mid-line or any other known approach to the disc space. These pre-fabricated devices can require the surgeon to modify the interbody device, the vertebral bodies, and/or the vertebral endplates to achieve a desired fit between the spinal anatomy and the interbody device. While some pre-fabricated devices can be modified before and during surgery by the surgeon, this is a time consuming task and also does not always result in a desired or optimum fit with the natural or altered spinal anatomy. Further, the various approaches and instruments required to insert pre-fabricated devices can be invasive and traumatic to the nervature, vasculature, and tissue between the skin and the disc space.
  • [0003]
    What is therefore needed are methods and devices for providing interbody devices in a disc space between vertebral bodies that allow the surgeon to achieve a desired or optimum fit between the device and the natural or altered spinal anatomy. What is also needed are devices and methods for preparing a disc space for an interbody device while minimizing invasion into the tissue between the skin and the subject disc space. What is further needed are improved devices and methods for performing spinal surgery. What is also needed are methods and devices for providing interbody fusion utilizing minimally invasive approaches and instruments. The present invention is directed toward meeting these needs, among others.
  • SUMMARY OF THE INVENTION
  • [0004]
    According to one aspect of the present invention, there is provided a form positionable in a spinal disc space and an interbody device made from material that has a first condition allowing placement around the form and in contact with the vertebral endplates and thereafter the material has a second condition that provides structural support between the endplates.
  • [0005]
    According to another aspect of the invention, there is provided a distractor for a disc space that has a reduced-size configuration for insertion into a disc space and an enlarged configuration for distracting the disc space and for defining a void between the enlarged portion and the inner wall of the disc space annulus.
  • [0006]
    According to yet another aspect of the invention, a spinal disc space distractor provides an intradiscal form around which an interbody device is placed.
  • [0007]
    According to a further aspect of the invention, a spinal disc space distractor having an enlargeable portion is provided.
  • [0008]
    According to a further aspect of the invention, a spinal disc space distractor having an enlargeable portion with upper and lower vertebral endplate contact surfaces with predetermined areas is provided.
  • [0009]
    According to another aspect of the invention, a surgeon inserts a distractor in a spinal disc space and places a first material around the distractor and between the vertebral endplates. When the first material cures, the distractor is withdrawn and a second material is placed in the disc space in the space that was occupied by the distractor.
  • [0010]
    According to a further aspect of the invention, multiple distractors having enlargeable distracting portions are inserted in the disc space to form a void for receiving a first material
  • [0011]
    According to another aspect of the invention, a disc space is bi-laterally distracted by inserting an enlargeable portion of a first distractor at a first lateral disc space location and an enlargeable portion of a second distractor at a second lateral disc space location. Scoliosis can be addressed by providing the enlargeable portions with different distraction heights.
  • [0012]
    According to a further aspect of the invention, a spinal disc space distractor having an enlargeable portion of a predetermined shape is provided. The predetermined shape is selected from one of the following: vertically-oriented cylinder, horizontally-oriented cylinder, sphere, cylindrical center portion with frusto-conical tapered ends; banana-shaped, and pear shaped.
  • [0013]
    These and other aspects, forms, features and advantages will be apparent from the following description of the illustrated embodiments.
  • BRIEF DESCRIPTION OF THE DRAWINGS
  • [0014]
    [0014]FIG. 1 is diagrammatic illustration in the axial plane of a spinal disc space with instruments positioned therein for performing a discectomy procedure.
  • [0015]
    [0015]FIG. 2a is a diagrammatic illustration of the disc space of FIG. 1 with a distractor having an enlargeable portion positioned therein.
  • [0016]
    [0016]FIG. 2b is a diagrammatic illustration looking in the direction transverse to the sagittal plane of the spinal column segment encompassing the disc space and the distractor of FIG. 2a.
  • [0017]
    [0017]FIG. 3a is a diagrammatic illustration of the disc space of FIG. 2a with the distractor disposed therein along with a material delivery instrument.
  • [0018]
    [0018]FIG. 3b is a diagrammatic illustration of the disc space of FIG. 3a with a first material being delivered around the enlarged portion of the distractor.
  • [0019]
    [0019]FIG. 3c is a sectional view of an alternate embodiment enlargeable distractor and material delivery instrument according to the present invention.
  • [0020]
    [0020]FIG. 4 is a diagrammatic illustration of the disc space of FIG. 3b after the first material has cured and the enlargeable portion of the distractor in a reduced size configuration for removal from the disc space.
  • [0021]
    [0021]FIG. 5 is a diagrammatic illustration of the disc space of FIG. 4 with a second material in the disc space within the cured material.
  • [0022]
    [0022]FIG. 6 is a diagrammatic illustration of in partial section through line 6-6 of FIG. 5.
  • [0023]
    [0023]FIG. 7 is a diagrammatic illustration of the partial sectional view of FIG. 7 showing posterior stabilization instrumentation secured to the spinal column segment across the disc space.
  • [0024]
    [0024]FIG. 8 is a diagrammatic illustration in the axial plane of a spinal disc space having a pair of distractors having enlargeable portions for bi-lateral distraction of the disc space.
  • [0025]
    [0025]FIG. 9 is a diagrammatic illustration of a spinal disc space having another arrangement for dual distractors along with a first material positioned at a first lateral location in the disc space.
  • [0026]
    [0026]FIGS. 10a-10 c show a side view, an end view and a plan view, respectively, of one embodiment of an inflatable distractor.
  • [0027]
    [0027]FIGS. 11a-11 c show a side view, an end view and a plan view, respectively, of another embodiment inflatable distractor.
  • [0028]
    [0028]FIGS. 12a-12 c show a side view, an end view and a plan view, respectively, of another embodiment inflatable distractor.
  • [0029]
    [0029]FIGS. 13a-13 c show a side view, an end view and a plan view, respectively, of another embodiment inflatable distractor.
  • [0030]
    [0030]FIGS. 14a-14 c show a side view, an end view and a plan view, respectively, of another embodiment inflatable distractor.
  • [0031]
    [0031]FIGS. 15a-15 c show a side view, an end view and a plan view, respectively, of another embodiment inflatable distractor.
  • [0032]
    [0032]FIGS. 16a-16 c show a side view, an end view and a plan view, respectively, of another embodiment inflatable distractor.
  • [0033]
    [0033]FIGS. 17a-17 c show a side view, an end view and a plan view, respectively, of another embodiment inflatable distractor.
  • [0034]
    [0034]FIG. 18 is a graphical representation of the load applied to the vertebral endplates versus inflation pressure for inflatable distractors having various vertebral endplate contact areas.
  • DESCRIPTION OF THE ILLUSTRATED EMBODIMENTS
  • [0035]
    For the purposes of promoting an understanding of the principles of the invention, reference will now be made to the embodiments illustrated in the drawings and specific language will be used to describe the same. It will nevertheless be understood that no limitation of the scope of the invention is thereby intended. Any such alterations and further modifications in the illustrated devices, and any such further applications of the principles of the invention as illustrated herein are contemplated as would normally occur to one skilled in the art to which the invention relates.
  • [0036]
    The present invention provides techniques for forming interbody devices in a disc space of the spinal column. It is contemplated that techniques of the present invention utilize minimally invasive endoscopic instruments and methods for performing discectomy and other disc space preparatory procedures. However, open surgical techniques and other visualization instruments and techniques are also contemplated. In techniques where the interbody device is part of a spinal fusion procedure, percutaneous stabilization and fixation techniques through the pedicles or facets are also possible after completing insertion of the interbody device. The present invention further provides minimally invasive techniques for segmental stabilization of a spinal disc space to repair a spinal disc space due to, for example, disc space collapse or progressive mono-segmental instability which are normally repaired via discectomy procedures that do not include interbody fusion. The present invention has application from any approach to any disc space along the spinal column, including L5-S1. Further, the present invention has application in a bi-portal, postero-lateral approach to one or disc spaces in the lumbar region of the spine.
  • [0037]
    Reference will now be made to FIGS. 1-7 to describe methods, instruments and materials according to the present invention to provide an interbody device formed in situ in the disc space that conforms with the patient's vertebral endplate anatomy. FIG. 1 shows an outline in plan view of a spinal disc space and lower vertebral body 10 b in plan view during a discectomy procedure. The anterior aspect of the spinal column is indicated by “A” and the posterior side is indicated by “P.” The lateral aspects of the spinal column extend between A and P on each side the spinal column. As shown further in FIG. 2b, the subject spinal disc space is located between an upper vertebra 10 a having an inferior endplate 11 a and a lower vertebral 10 b having a superior endplate 11 b. The disc space has a nucleus 12 that is surrounded by an annulus 14. First and second pedicles 16 a extend posteriorly from upper vertebral body 10 a, and first and second pedicles 16 b extend posteriorly from lower vertebral body 10 b. The spinal cord or dura 17 extends along the posterior aspect of vertebrae 10 a, 10 b.
  • [0038]
    In FIG. 1 there are shown instruments inserted via a bi-portal approach to the disc space that are useful in completing a nucleotomy or a discectomy of the spinal disc. The instruments for performing this procedure can include a scope 20 and a discectomy instrument 22. In the illustrated embodiment, discectomy instrument 22 and scope 20 are inserted through first access port 18 and second access port 19, respectively, in a postero-lateral approach to the disc space. Access ports 18, 19 can each be a working channel cannula to provide a protected first and second postero-lateral access ports to the disc space. It is to be understood that aspects of the present invention contemplate approaches and combinations of approaches to the disc space other than a postero-lateral approach, such as a lateral approach, anterior approach, or antero-lateral approaches. It should be understood that uni-portal disc space access is contemplated, as well as bi-portal disc space access from the same side of the spinal disc space or from differing approaches, such as a lateral approach and a postero-lateral approach. It is further contemplated that open surgical procedures could be utilized for the discectomy.
  • [0039]
    In one specific surgical technique used with the present invention, the disc space in the lumbar region of the spine is accessed endoscopically via a foraminal or postero-lateral, bi-portal approach. Cannulas and dilators can be used for access ports 18, 19 and catheters inserted therethrough for visualization, discectomy procedures, distraction, and material delivery. In these approaches, the outer cannulas can have an outside diameter of up to 7.5 millimeters and more typically in the range of about 6.5 millimeters. However, any sized cannula is contemplated so long as there is an acceptable level of trauma to the tissue and nerve structures.
  • [0040]
    To provide access ports 18, 19 in this specific technique, insertion begins 9 to 13 centimeters from the midline with a guidewire or discogram needle. The facet joint at the dome of the facet is initially targeted and palpated by the tip of the needle. The needle is withdrawn and re-angulated to go inside the dome, thus missing the exiting nerve root. The posterior vertebral bodyline is imaged fluoroscopically to document its resting position. The fluoro machine is then moved to an A-P position and the resting zone is either on the mid or lateral pendicular starting position for a postero-lateral approach or the medial pendicular midline for a foraminal approach. Needle insertion into the disc space can be completed simultaneously on the left and right hand sides. The needles can be triangulated to touch one another in the posterior central portion of the disc space or alignment can be adjusted and conformed via discography.
  • [0041]
    One or more dilators of increasing diameter are then sequentially placed over each of the needles to the annulus, and a cannula is placed over each of the final dilators to land on the annulus. The final dilators are removed and a trephine used through each cannula to cut holes in the annulus to allow for entry into the disc space. An endoscope can be used at any time throughout the procedure to document the presence of nerve roots or to observe the annulus prior to cutting. The final dilator is then re-inserted into each of the cannulas and impacted through the hole in the annulus and into the disc space. The final dilator thus secures the cannula into position and obstructs the annulus opening to ensure material is delivered into the disc space without excursion out of the disc space. The cannulas and dilators are then used as access portals to the disc space for completion of the remaining procedures, and also allow for the interchange of instruments between the left and right sides. Either one of the access ports 18, 19 can then be used for endoscopic visualization and the other access portal 18, 19 can be used for disc material removal with manual, automated, ultrasonic, laser, or any other disc material removal instruments desired by the surgeon.
  • [0042]
    After discectomy there is a prepared disc space 24. It can also be desired by the surgeon to expose and gently remove endplate cartilage and to remove all soft tissue and debris from within the disc space to expose the inner wall of the annulus. Inner portions of a minimally appropriate amount of the inner wall laminates of annulus 14 surrounding the removed nucleus can be removed to increase the lateral and anterior-posterior extent of the prepared disc space 24. The remaining portion of the annulus remains intact except for the access holes cut for instrument entry locations. An endoscope can be placed in one of the access portals to check disc material removal and to also check the annulus to ensure there are no wall defects requiring repair. In cases where interbody fusion is desired, the endplates can be prepared by eburnating the apophyseal ring to prepare it for bony fusion, and the vertebral endplates can be scraped or abraded to reduce them to bleeding bone. Right angle curettes or probes can also be inserted to make small protrusions or abrasions into the endplates to further facilitate fusion if so desired.
  • [0043]
    After disc space access and discectomy, the disc space will typically still be in a collapsed state, and the only distraction that has been completed at this point has been the result of insertion of the final dilator into the disc space. The disc space must now be further distracted to the desired disc space height and also to establish lordosis if desired or necessary. Referring now to FIGS. 2a-2 b, a distractor 30 is inserted into the prepared disc space 24. Distractor 30 has a shaft 32 extending between a distal end 36 and a proximal end 38 situated outside the disc space. Adjacent distal end 36 there is an enlargeable portion 34 positionable in prepared disc space 24. Enlargeable portion 34 is inserted into the disc space in a reduced size configuration, and after proper positioning in prepared disc space 12 is confirmed endoscopically, fluoroscopically or via any other visualization technique, is thereafter enlarged to contact endplates 11 a, 11 b and distract the disc space to the desired height.
  • [0044]
    Enlargeable portion 34 is sized with respect to prepared disc space 24 such that a void 26 is formed between the enlarged portion 34, inner wall of annulus 14, and the endplates 11 a, 11 b generally in the location of the apophyseal ring as shown in FIG. 3a. In one form, enlargeable portion 34 is an inflatable balloon or cuff-type structure that is inserted into the disc space in a deflated condition and thereafter inflated via an inflation lumen through shaft 32 to a predetermined pressure with air, gas, or liquid from an inflation source 39. A valve 37 can be provided on shaft 32 to block the lumen therethrough and maintain the inflation pressure in enlargeable portion 34. It is further contemplated that enlargeable portion 34 could be made from any material capable of assuming a reduced sized for insertion and withdrawal from the prepared disc space and enlargeable for disc space distraction, such as an elastomer, polymer, shape memory material or spring steel. Examples of various types of inflatable devices are described further below with respect to FIGS. 10-17.
  • [0045]
    In any event, enlargeable portion 34 is sized in the cephalad-caudal directions sufficiently to distract the spinal disc space to a desired normal disc space height and sized in the lateral and anterior-posterior directions to provide void 26 when enlarged. A single centrally placed enlargeable distractor 30 could utilize endplate geometry to create lordosis.
  • [0046]
    In addition to a single distractor having an enlargeable portion inserted into the disc space as shown above with respect to FIGS. 1-7, other distraction instruments and techniques are contemplated. For example, if the enlargeable portion of the distractor is inflatable, then the enlargeable portion 34 can be provided with dual chambers of differing heights to establish a lordotic effect. In another example, multiple distractors having different height enlargeable portions 34 can be inserted and positioned at the appropriate locations in the disc space and be enlarged together to provide the desired endplate angulation.
  • [0047]
    As further shown in FIGS. 3a and 3 b, with distractor 30 enlarged and maintaining disc space distraction, a material delivery instrument 40 is inserted into the disc space in the access port opposite the distractor access port. Material delivery instrument 40 includes a working channel 42 through which a first material 50 can be delivered through a distal opening 44 and into void 26. First material 50 has a first condition that allows it to be selectively placed, injected, flowed, moved or otherwise migrated around the enlargeable portion 34 in void 26 such that all or substantially all of void 26 is occupied by first material 50. First material 50 thereafter changes, cures or transforms from its first condition into a second condition in which it forms a solid or semi-solid interbody device 50′ in space 26, as shown in FIG. 4, capable of structurally supporting the vertebrae at the desired disc space height. Interbody device 50′ thus conforms to the patient's vertebral endplate anatomy and also conforms to the shape of void 26 between enlargeable portion 34 and annulus 14.
  • [0048]
    It is contemplated that first material 50 can be a cement, poly(methyl methacrylate), or any other bio-compatible material that has the structural capabilities to withstand the spinal column loads applied thereto. It is further contemplated that first material 50 can be delivered in a first condition through an instrument channel or lumen of instrument 40 and thereafter changed to a second condition via any natural or chemically induced or enhanced reaction to form an interbody device 50′. First material 50 can further be static or include bio-active material to promote bone growth.
  • [0049]
    While delivery instrument 40 is illustrated as an instrument separate from distractor 30, it is also contemplated that distractor 30 could be provided with a working channel for delivery of first material 50 to void 26 or second material 60 to central space 52′. For example, as shown in FIG. 3c, distractor 30′ has a shaft 32′ and an inflatable enlargeable portion 34′. Shaft 32′ defines an inflation lumen 32 a′ in communication with the interior of enlargeable portion 34′. Shaft 32′ further include a material delivery lumen 32 b′ extending through enlargeable portion 34′ and opening at distal end 36′. After distraction with enlargeable portion 34′, first material 50 can be delivered through lumen 32 b′ into void 26. Such an instrument could be employed for uni-portal material delivery and disc space distraction, or used in combination with material delivery instrument 40 or another distractor 30′ in the opposite access port to provide bi-portal material delivery. It is further contemplated that delivery instrument 40 can be a flexible cannula or catheter that can be moved or manipulated around void 26 in order to deliver first material 50 to all portions thereof. Material delivery instrument 40 can further be provided with endoscopic capabilities to allow visualization and direct viewing of material delivery.
  • [0050]
    In another form, one or more flexible material delivery catheters can be placed over a guide wire extending through one of the access portals and into the disc space around enlargeable portion 34 and at various locations in void 26. The flexible catheter(s) can be placed through only one or both of the access portals 18, 19. With the desired distraction achieved and the material delivery catheters positioned as desired, the guide wires are removed and first material 50 delivered through the flexible catheter(s). First material 50 can be delivered sequentially through the catheters or simultaneously through the catheters to provide an interbody device 50′ that is completely formed about enlargeable portion 34 except for an entry port to central cavity 52′. Interbody device 50′ thus provides balanced spinal load support on the apophyseal ring. Second material 60 can then be placed centrally into the interbody device in the central cavity 52′ previously occupied by the withdrawn enlargeable portion 34 of distractor 30.
  • [0051]
    One specific technique for placement of first material 50 via bi-portal, postero-lateral access ports was completed as follows. The material delivery instrument 40 included first and second material delivery catheters each placed in a respective one of the first and second access ports 18 and 19. First material 50 was delivered through one catheter through the first access port under low pressure until the presence of first material 50 was detected at the distal end of the first access port or the second access port. The catheter was then slowly pulled back through the first access port until first material 50 was delivered to the distal end of the first access port housing the first delivery catheter. Thereafter the first material delivery catheter was withdrawn. First material 50 was then delivered through the second material delivery catheter positioned in the second access port until first material 50 was detected at the distal end of either of the second access port or the first access port. The second material delivery catheter was then pulled back through the second access port, thereby completely filling the void 26 with first material 50.
  • [0052]
    Several factors are to be considered in placing first material 50 in the disc space. For example, if first material 50 were a cement, factors to consider include the liquidity of the cement, the cure temperature of the cement and the insertion pressure of the cement. If the cement has a relatively cool temperature, then more time is required for the cement to cure which increase operating room time. Curing time can also be affected by adding other substances to it, such as growth factors, antibiotics and/or barium tracer. The injection pressure of first material 50 can affect whether it will leak out of small tears in the annulus or infiltrate interstices and nutrient canals of the vertebral endplates. It is also desirable that placement procedures for first material be carried out under fluoroscopy with a tracer such as barium in first material 50 to allow monitoring of material excursion and its presence in the disc space. Monitoring of the placement of first material 50 to confirm its proper positioning in the disc space can be accomplished by AP and lateral fluoroscopy or bi-planar fluoroscopy. The presence of material excursion could signify a significant annulus or other anatomical or surgically created defect or void. Such monitoring provides a safety measure to ensure first material 50 is not placed into inappropriate anatomic locations during formation of interbody device 50′.
  • [0053]
    Referring further to FIG. 4, enlargeable portion 34 is returned to its reduced size configuration so it can be removed from interbody device 50′ and the disc space. This leaves a central cavity 52′ surrounded by interbody device 50′. An endoscope 20 can be used to monitor distractor withdrawal and to check the integrity of interbody device 50′. Material delivery instrument 40 can then be repositioned, if necessary, in one of the access portals and used to deliver a second material 60 to central cavity 52′ as shown in FIG. 5. Second material 60 can be artificial disc material, bioactive substance, rhBMP, autograft, or bioactive or osteoconductive carrier for bony fusion. In situations where second material 60 is fusion material, bony fusion can occur centrally while interbody device 50′ provides stability of the disc space during fusion. It is further contemplated that in situations where fusion is desired, the endplates 11 a, 11 b could be reduced to bleeding bone via scraping, cutting, or reaming prior to placement of second material 60.
  • [0054]
    Referring now to FIG. 6, there is shown a partial section view of the spinal column segment having interbody device 50′ formed in a disc space as described above. Interbody device 50′ conforms with the shape of endplates 11 a, 11 b and constrains second material 60 therein. In FIG. 7, there are shown posterior screws 46 a, 46 b secured to pedicles 16 a, 16 b and a rod 48 extending between and secured thereto. It is further contemplated that posterior stabilization could be provided with screws at the facet joints, or via a posterior plate secured to the vertebrae. Anterior or lateral stabilization plates secured to the vertebrae are also contemplated. Such supplemental fixation and stabilization devices are known in the art and will not be described further herein.
  • [0055]
    Referring now to FIG. 8, there is shown another technique for forming an interbody device in a spinal disc space. The instruments used in the technique of FIG. 8 include a left side lateral distractor 70 a and a right side lateral distractor 70 b that is substantially identical to left side distractor 70 a. Lateral distractors 70 a, 70 b each include shafts 72 a, 72 b and an enlargeable portion 74 a, 74 b, respectively, adjacent a distal end of the respective shaft. If enlargeable portions 74 a, 74 b were inflatable, shafts 72 a, 72 b would also define an inflation lumen. After completing procedures to form a prepared disc space as discussed above, lateral distractors 70 a, 70 b are positioned through bi-portal access ports 18, 19 and into the disc space 24. Enlargeable portions 74 a, 74 b each have a concavo-convex or banana-shaped configuration so that each can be positioned along the inner annulus wall and the apophyseal ring of the upper and lower vertebrae 10 a, 10 b while leaving the central portion of the disc space open. Further, the apophyseal ring in its most anterior portion between the distal tips of enlargeable portions 74 a, 74 b remains open for placement of material 50 and also remains open along its most posterior portion between the distal ends of enlargeable portions 74 a, 74 b. For example, as shown in FIG. 8, first material 50 has been placed in the anterior portion of the disc space by a material delivery instrument or catheter inserted through one of the access portals 18, 19 alongside the distractor to form a first interbody device segment 50″ when cured. First material 50 could also be placed in the posterior portion to form a second interbody device segment (not shown). Additional interbody segments or pillars could be formed in the disc space, and second material 60 could then be placed or packed between the interbody segments.
  • [0056]
    There are several distraction and material placement techniques afforded by use of lateral distractors as shown in FIG. 8. For example, after sequential bi-lateral distraction of the disc space, one of the lateral distractors could be reduced in size and withdrawn and this same side of the disc space could be provided with first material 50 from delivery instrument 40 to form a first lateral interbody device segment 50 a as shown in FIG. 9. A single central distractor 30 can be used to block the central portion of the prepared disc space 24 while second lateral distractor 70 b blocks the right lateral side of the disc space. Second lateral distractor 70 b can then be withdrawn and additional first material 50 is provided to form a second interbody device segment (not shown) using enlargeable portion 34 as a form. After completion of the interbody device segments, second material 60 can be delivered into the space between the interbody device segments. Further, sequential distraction can be done in such a way that two lateral distractors 70 a, 70 b are left in prepared disc space 24 and second material 60 can be placed between the lateral distractors 70 a, 70 b. Second material 60 can then be used alone or in combination with one of the lateral distractors 70 a, 70 b as a form for placement of first material 50.
  • [0057]
    It is further contemplated that the placement location for first material 50 can be varied at any location about the apophyseal ring by using combinations of lateral distractors, anterior and posterior distractors, and central distractors. Further, it is contemplated first material 50 could be placed at multiple, discrete locations about the apophyseal ring to provide a number of columnar or segmented interbody devices in the disc space. These segmented interbody devices could be formed adjacent to and in contact with one another or formed with gaps therebetween. It is further contemplated that the positioning of the various interbody devices could be varied to accommodate the approach desired for material placement, including both uni-lateral injection or a bi-lateral placement.
  • [0058]
    In another embodiment, the banana-shaped lateral distractors 70 a, 70 b can be tapered in height to provide angulation between the vertebral endplates. For example, lordosis could be established by providing the enlargeable portions 74 a, 74 b with a greater height posteriorly than anteriorly. Further, the lateral distractors 70 a, 70 b can be provided with differing heights in order to distract one side of the disc space more than the other side, reducing or eliminating scoliosis. Alternatively, identical inflatable devices could be provided in which the inflatable portions have a height that corresponds to the internal inflation pressure supplied thereto. One of the lateral distractors could be inflated to a greater pressure than the contra-lateral side to provide differential distraction heights for each side. The same lateral distractor could be employed bi-laterally to change the lateral angulation of the disc space by varying the inflation pressure supplied to the enlargeable portion thereof.
  • [0059]
    After repairing scoliosis by providing the appropriate distraction and interbody devices, the disc space occupied by the enlargeable portions of the distractor is available for placement of bone growth material. For example, if two banana-shaped inflatable devices are used, a central cavity encompassed by the enlargeable portions remains after the portions are enlarged. Second material can then be placed in this central cavity. Additional first material can then be placed in the space previously occupied by the enlarged portions to provide structural peripheral support. Thus, this specific example contemplates initially central placement of a first material, such as bone growth material, and then the enlargeable distractors can be sequentially or simultaneously withdrawn from the disc space and a second material, such as a cement, placed around the central core of first material and against the enlargeable distractor portion, if any, remaining in the disc space to provide structural support of the disc space.
  • [0060]
    As discussed above, enlargeable portion 34 of the distractor 30 can be an inflatable device. In FIGS. 10-17, there are provided various embodiments of inflatable devices that can be used to perform disc space distraction. By providing inflatable devices of various shapes and sizes, different vertebral endplate contact areas can be formed thereby providing selection of the optimal inflatable device based on vertebral endplate load resistance, required distraction force, and the structural integrity of the pressurized inflated device. It should be understood, however, that the contact surface areas provided below are estimated based on a distraction height of 14 millimeters. The contact surface area of each balloon will vary depending on the degree to which the balloon is inflated. For distraction heights less than 14 millimeters, the contact are will be greater than 0.2 square inches. For distraction heights greater than 14 millimeters, the contact are will be less than 0.2 square inches. It should be further understood that the contact area for each balloon can be varied by changing the lateral and/or anterior-posterior dimensions of the balloon while retaining the same balloon shape.
  • [0061]
    Referring now to FIGS. 10a-10 c, there is shown a first embodiment an inflatable device in the form of a balloon 100 having the shape of a center cylinder with frusto-conically tapered ends extending therefrom. Balloon 100 is in communication with an inflation lumen 102 and has upper vertebral endplate contacting surface 104 and opposite lower vertebral endplate contacting surface 106. As shown in FIG. 10b, surfaces 104, 106 have an oval shape with the rounded end portions of the oval positioned laterally of a longitudinal axis extending through inflation lumen 102 and balloon 100. Surfaces 104, 106 contact endplates 11 a, 11 b of the upper and lower vertebrae 10 a, 10 b, respectively, as shown in FIG. 10c. Balloon 100 has a central cylindrical portion 108 which defines contact surfaces 104, 106, and opposite frusto-conical portions 110, 112 distally and proximally extending therefrom, respectively, and tapered at an angle that avoids contact with the vertebral endplates. In one specific embodiment, it is estimated that balloon 100 has a contact surface area of about 0.2 square inches for each of the upper and lower contact surfaces 104, 106 when balloon 100 is expanded to distract the disc space to a height of 14 millimeters.
  • [0062]
    Referring now to FIGS. 11a-11 c, there is shown another embodiment of an inflatable device in the form of a balloon 120 having a shape of a center cylinder with a pair of frusto-conically tapered ends extending from each end thereof. Balloon 120 is in communication with inflation lumen 122 and has upper vertebral endplate contacting surface 124 and opposite lower vertebral endplate contacting surface 126. As shown in FIG. 11b, surfaces 124, 126 have an oval shape with the rounded portions oriented distally and proximally along a longitudinal axis extending through inflation lumen 122 and balloon 120. Surfaces 124, 126 contact endplates 11 a, 11 b of the upper and lower vertebrae 10 a, 10 b, respectively, as shown in FIG. 11c. Balloon 120 has a central cylindrical portion 128 which defines a portion of contact surfaces 124, 126. Balloon 120 further includes first frusto-conical portions 130, 132 extending distally and proximally therefrom, respectively, which define the remaining portions of contact surfaces 124, 126. Frusto-conical portions 130, 132 are only tapered slightly and generally match the curvature of the vertebral endplates in order to provide additional contact area as compared to balloon 100. In one specific embodiment, balloon 120 has a contact surface area of about 0.3 square inches for each of the upper and lower contact surfaces 124, 126. Distal frusto-conical portion 134 and proximal frusto-conical portion 136 extend to the distal end of balloon 120 and to inflation lumen 122, respectively, and generally do not contact the vertebral endplates unless the balloon is sufficiently inflated to create such contact.
  • [0063]
    Referring to FIGS. 12a-12 c, there is shown another embodiment an inflatable device in the form of a balloon 140 having a vertically oriented cylindrical shape. Balloon 140 is in communication with an inflation lumen 142 and has upper vertebral endplate contacting surface 144 and opposite lower vertebral endplate contacting surface 146. Surfaces 144, 146 contact endplates 11 a, 11 b of the upper and lower vertebrae 10 a, 10 b, respectively, as shown in FIG. 12c. Balloon 140 has a cylindrical body 148 which has circular upper and lower ends 150, 152 that define circular contact surfaces 144, 146 as shown in FIG. 12b. In one specific embodiment, balloon 140 has a contact surface area of about 0.5 square inches for each of the upper and lower contact surfaces 144, 146.
  • [0064]
    Referring now to FIGS. 13a-13 c, there is shown another embodiment an inflatable device in the form of a balloon 160 having a horizontally oriented cylindrical shape. Balloon 160 in communication with an inflation lumen 162 and has a cylindrical body 168 with distal end 170 and opposite proximal end 172. Balloon 160 further includes upper vertebral endplate contacting surface 164 and opposite lower vertebral endplate contacting surface 166. As shown in FIG. 13b, contact surfaces 164, 166 have a substantially rectangular shape formed by the contact between the cylindrical sidewalls of cylindrical body 168 and endplates 11 a, 11 b of the upper and lower vertebrae 10 a, 10 brespectively. In one specific embodiment, balloon 160 has a contact surface area of about 0.24 square inches for each of the upper and lower contact surfaces 164, 166.
  • [0065]
    Referring to FIGS. 14a-14 c, there is shown another embodiment an inflatable device in the form of a balloon 180 having a horizontally oriented cylindrical shape. Balloon 180 is in communication with inflation lumen 182 and has a cylindrical body 188 with distal end 190 and opposite proximal end 192. Balloon 180 further includes upper vertebral endplate contacting surface 184 and opposite lower vertebral endplate contacting surface 186. As shown in FIG. 14b, contact surfaces 184, 186 have a rectangular shape formed by the contact between the cylindrical sidewalls of cylindrical body 188 and endplates 11 a, 11 b of the upper and lower vertebrae 10 a, 10 b, respectively. In one specific embodiment, balloon 180 has a contact surface area of about 0.3 square inches for each of the upper and lower contact surfaces 184, 186. Balloon 180 is similar in shape to balloon 160, but has a shorter length between its distal and proximal ends to allow balloon 180 to extend further laterally in the disc space than balloon 160 and thus increasing the vertebral endplate contact area.
  • [0066]
    Referring to FIGS. 15a-15 c, there is shown another embodiment an inflatable device in the form of a balloon 200 having a spherical shape. Balloon 200 is in communication with an inflation lumen 202 and has upper vertebral endplate contacting surface 204 and opposite lower vertebral endplate contacting surface 206. Surfaces 204, 206 are formed on spherical body 208 and have a circular shape in contact with endplates 11 a, 11 b of the upper and lower vertebrae 10 a, 10 b, respectively. Spherical body 208 has opposite distal and proximal ends 210, 212 respectively. In one specific embodiment, balloon 200 has a diameter of 22 millimeters which provides a contact surface area of about 0.35 square inches for each of the upper and lower contact surfaces 204, 206.
  • [0067]
    In FIGS. 16a-16 c there is shown another embodiment spherically shaped balloon 220 having a spherical body 228 in communication with inflation lumen 222. Spherical body 228 includes contact surfaces 224, 226 forming a circular contact surface with endplates 11 a, 11 b. In this embodiment, balloon 220 has a diameter of 24 millimeters and the endplate contact surface areas of surfaces 224, 226 are each 0.45 square inches.
  • [0068]
    Referring now to FIG. 17, there is shown an inflatable device having a pear shaped balloon 240 in fluid communication with an inflation shaft 242. Balloon 240 includes upper surface 244 and an opposite lower surface 246. Upper surface 244 has first vertebral endplate contacting node 244 a, a second vertebral endplate contacting node 244 b and a concave portion 244 c extending therebetween. Similarly, lower surface 246 has first vertebral endplate contacting node 246 a, a second vertebral endplate contacting node 246 b and a concave portion 246 c extending therebetween. Balloon 240 is shaped such that the contacting nodes are positionable at the apophyseal ring and the concave surfaces span weaker bony material at the central portion of the vertebral endplate. It is further contemplated that such a shape could be provided to establish lordosis by, for example, providing the anteriorly positioned node with a height less than the posteriorly oriented node.
  • [0069]
    In addition to the above-described shapes, other shapes for the enlargeable portion 34 of distractor 30 are also contemplated. For example, the enlargeable portion can have a shape that corresponds to the shape of the vertebral endplates, such as a kidney bean shape, or can have a square or rectangular cuboid shape. It is also desirable that first material 50 does not adhere to the enlargeable portion 34 while it is curing. Thus, various coatings can be applied to the exterior surface of enlargeable portion 34 such as, for example, Teflon spray or silicone oil. Other coatings are also contemplated, so long as they prevent the adhesion of first material 50 and enlargeable portion 34. For embodiments in which enlargeable portion 34 is an inflatable device, the device should also be made from a tough yet elastic material that can withstand the inflation pressures applied thereto while also retaining the capability to return to a reduced size configuration for insertion and withdrawal from the disc space and through the access port.
  • [0070]
    The inflatable devices of the present invention can be designed to accommodate the patient anatomy. One factor considered in such a design is the force required to distract the disc space to the desired disc space height. The ability of the vertebral endplates to resist contact pressure has been found to decrease with patient age. For example, one study found those persons in the range of 20-30 years have a vertebral endplate resistance capability of 1500 pounds per square inch, those persons in the range of 40-60 year olds have a vertebral endplate resistance capability of 1050 pounds per square inch, and those persons over 60 year olds have a vertebral endplate resistance capability of 594 pounds per square inch. In order to distract the disc space with an inflatable device, sufficient pressure must be exerted to overcome the tension from the muscles and ligaments that have become accustomed to the collapsed condition of the disc space. However, the pressure on the vertebral endplates must remain within acceptable limits.
  • [0071]
    Based on the contact area of the balloon, the load the balloon will exert on the vertebral endplates to distract the disc space can be determined. The pressure exerted on the vertebral endplates can also be determined and the balloon sized so that the contact pressure does not exceed the vertebral endplate resistance capability of the patient. The following table presents the maximum allowable load for various balloon contact areas based on the vertebral endplate resistance for the patient ranges provided above:
    Maximum Allowable Endplate Load
    Contact Area 20-30 yr olds 40-60 yr olds 60+ yr olds
    0.5 sq. in. 750 lbs 525 lbs 297 lbs
    0.4 sq. in. 600 lbs 420 lbs 238 lbs
    0.3 sq. in. 450 lbs 315 lbs 178 lbs
    0.2 sq. in. 300 lbs 210 lbs 119 lbs
    0.1 sq. in. 150 lbs 105 lbs  59 lbs
  • [0072]
    As shown in FIG. 18, a graphical representation is provided to represent the relationship between the balloon pressure and the load exerted by the balloon for various sizes of contact areas for the balloons ranging between 0.1 square inches to 0.5 square inches. From this information, a balloon contact area size and pressure can selected that is within the maximum allowable load for a particular patient. For example, if 100 pounds is required to distract the vertebrae to the desired height, then a balloon having contact surface areas of 0.5 square inches would apply a vertebral endplate load of about 100 pounds at an inflation pressure of 200 psi. The distraction load of 100 pounds for the 0.5 square inch contact area is well below the maximum allowable endplate load for each of the patient age ranges provided above.
  • [0073]
    While the invention has been illustrated and described in detail in the drawings and foregoing description, the same is to be considered as illustrative and not restrictive in character, it being understood that only the preferred embodiment has been shown and described and that all changes and modifications that come within the spirit of the invention are desired to be protected.

Claims (47)

    What is claimed is:
  1. 1. A method for performing spinal surgery, comprising:
    accessing a disc space between adjacent vertebrae;
    performing a discectomy in the interspace;
    inserting an enlargeable portion of a distractor into the disc space;
    enlarging the enlargeable portion of the distractor to distract the disc space to a desired disc space height, wherein the enlarged enlargeable portion is sized to form a void in the disc space between the annulus and an exterior surface of the enlarged enlargeable portion; and
    placing a material into the void.
  2. 2. The method of claim 1, further comprising:
    curing the material;
    reducing the size of the enlargeable portion of the distractor after the material is cured; and
    removing the reduced enlargeable portion of the distractor from the disc space.
  3. 3. The method of claim 2, further comprising:
    placing a second material in the space previously occupied by the enlargeable portion.
  4. 4. The method of claim 3, wherein the cured material and the vertebral endplates substantially encapsulate the second material.
  5. 5. The method of claim 3, wherein the second material is bone growth material.
  6. 6. The method of claim 1, wherein the material is a cement.
  7. 7. The method of claim 1, wherein enlarging the enlargeable portion of the distractor includes inflating the enlargeable portion of the distractor.
  8. 8. The method of claim 7, wherein the enlarged portion of the distractor is deflated to remove the enlargeable portion from the disc space.
  9. 9. The method of claim 1, further comprising:
    removing cartilaginous material from the vertebral endplates before inserting the enlargeable portion of the distractor; and
    removing a portion of the inner wall of the annulus before inserting the enlargeable portion of the distractor.
  10. 10. The method of claim 1, further comprising selecting a distractor including an enlargeable portion having a predetermined vertebral endplate contact area.
  11. 11. The method of claim 1, further comprising inserting an enlargeable portion of a second distractor in the disc space with the enlargeable portion of the distractor.
  12. 12. The method of claim 11, further comprising enlarging the enlargeable portion of the second distractor, wherein an inner wall of an annulus encompassing the disc space, the enlarged enlargeable portion of the distractor and the enlarged enlargeable portion of the second distractor form the void.
  13. 13. The method of claim 12, further comprising:
    curing the material;
    reducing the size of the enlargeable portion of the distractor after the material is cured;
    removing the reduced enlargeable portion of the distractor from the disc space; and
    placing material into the space previously occupied by the enlarged enlargeable portion of the distractor with the enlargeable portion of the second distractor remaining in disc space.
  14. 14. The method of claim 13, further comprising:
    curing the material placed in the space;
    reducing the size of the enlargeable portion of the second distractor;
    withdrawing the enlargeable portion of the second distractor from the disc space; and
    placing a second material in the space previously occupied by the enlargeable portion of the second distractor.
  15. 15. The method of claim 11, wherein the enlargeable portion of the distractor is positioned at a first lateral location in the disc space and the enlargeable portion of the second distractor is centrally positioned in the disc space.
  16. 16. The method of claim 11, wherein the enlargeable portion of the distractor is positioned at a first lateral location in the disc space and the enlargeable portion of the second distractor is positioned at a second lateral location in the disc space.
  17. 17. The method of claim 1, wherein accessing the disc space includes:
    forming a first access port at a first postero-lateral location of the spine; and
    forming a second access port at a second postero-lateral location of the spine.
  18. 18. The method of claim 1, wherein accessing the disc space includes accessing the disc space from an uni-portal approach.
  19. 19. The method of claim 1, wherein accessing the disc space includes accessing the disc space from a foraminal approach.
  20. 20. The method of claim 1, wherein the enlargeable portion of the distractor is configured to establish lordosis of the disc space.
  21. 21. A method for performing spinal surgery in an interspace between adjacent vertebrae, comprising:
    providing a distractor having an inflatable distal end portion defining upper and lower vertebral endplate contact surfaces having a predetermined area;
    inserting the inflatable distal end portion of the distractor into the interspace;
    inflating the distal end portion of the distractor to distract the interspace to a desired interspace height, wherein a void is formed in the interspace between the annulus and the inflated portion; and
    placing material into the void.
  22. 22. A method for performing spinal surgery, comprising:
    accessing a disc space between adjacent vertebrae;
    performing a discectomy in the interspace;
    inserting an enlargeable portion of a distractor into the disc space;
    enlarging the enlargeable portion of the distractor to distract the disc space to a desired disc space height, wherein the enlarged enlargeable portion is sized to form a void in the disc space between the annulus and an exterior surface of the enlarged enlargeable portion;
    placing a material into the void;
    reducing the size of the enlargeable portion of the distractor after the material is placed; and
    removing the reduced enlargeable portion of the distractor from the disc space.
  23. 23. A method for performing spinal surgery in an interspace between adjacent vertebrae, comprising:
    providing a distractor having an inflatable distal end portion defining upper and lower vertebral endplate contact surfaces having a predetermined area;
    inserting the inflatable distal end portion of the distractor into the interspace;
    inflating the distal end portion of the distractor to distract the interspace to a desired interspace height, wherein a void is formed in the interspace between the annulus and the inflated portion;
    placing material into the void.
    reducing the size of the enlargeable portion of the distractor after the material is placed; and
    removing the reduced enlargeable portion of the distractor from the disc space
  24. 24. A method for performing spinal surgery in the disc space between adjacent vertebrae, comprising:
    providing a first distractor having an inflatable distal end portion defining upper and lower vertebral endplate contact surfaces;
    accessing the disc space from at least one access port;
    inserting the inflatable distal end portion of the first distractor into the disc space through the at least one access port;
    inserting the inflatable distal end portion of the second distractor into the disc space through the at least one access port; and
    inflating the first and second distal end portions to distract the disc space.
  25. 25. The method of claim 24, wherein a void is formed in the disc space between the inflated first and second inflatable distal end portions and the annulus; and further comprising placing material into the void.
  26. 26. The method of claim 24, wherein the inflatable distal end portion of the first distractor has a distraction height that differs from a distraction height of the inflatable distal end portion of the second distractor.
  27. 27. The method of claim 24, wherein:
    the inflatable distal end portions of the first and second distractors each define a banana shape;
    accessing the disc space includes accessing the disc space with opposite first and second postero-lateral access ports;
    the first distractor is positionable through the first access port with its banana shaped distal end portion positioned along a first portion of the apophyseal ring of the vertebral endplates; and
    the second distractor is positionable through the second access port with its banana shaped distal end portion positioned along a second portion of the apophyseal ring of the vertebral endplates.
  28. 28. The method of claim 27, wherein the inflatable distal end portion of the first distractor has a distraction height that differs from a distraction height of the inflatable distal end portion of the second distractor.
  29. 29. The method of claim 24, wherein the at least one access port provides a postero-lateral approach to the disc space.
  30. 30. A method for performing spinal surgery, comprising:
    preparing a spinal disc space for insertion of a form;
    positioning the form in the spinal disc space wherein a void is formed around the form;
    placing a first material in the void and in contact with the vertebral endplates on either side of the spinal disc space;
    removing the form; and
    placing a second material in the position that was occupied by the removed form.
  31. 31. The method of claim 30, wherein the first material has a fluid state while placing the first material and after placing the first material changes to a second condition after wherein the first material provides a solid interbody device extending between the vertebral endplates.
  32. 32. The method of claim 30, wherein the form is an enlargeable portion of a distractor.
  33. 33. The method of claim 30, wherein preparing the spinal disc space includes:
    accessing the spinal disc space from a pair of opposite ports each inserted from a postero-lateral approach; and
    performing a discectomy through at least one of the ports.
  34. 34. A method for performing spinal surgery, comprising:
    preparing a spinal disc space for placement of a first material therein;
    forming a void in the spinal disc space;
    placing a first material in the void and in contact with vertebral endplates on either side of the spinal disc space and in contact with an inner annulus wall;
    forming a cavity in the first material; and
    placing a second material in the cavity.
  35. 35. The method of claim 34, wherein forming the void includes:
    inserting an enlargeable portion of a distractor into the disc space in a reduced-size configuration; and
    enlarging the enlargeable portion of the distractor in the disc space.
  36. 36. The method of claim 35, wherein enlarging the distractor distracts the disc space to a desired disc space height.
  37. 37. A spinal surgical instrument for distracting a disc space, comprising:
    a shaft extending between a proximal end and a distal end; and
    an inflatable portion adjacent said distal end, said inflatable portion having a reduced size configuration for insertion into the disc space and an enlarged inflated configuration, wherein when in said inflated configuration said inflatable portion defines an upper vertebral endplate contacting surface and an opposite lower vertebral endplate contacting surface, each of said upper and lower vertebral endplate contacting surfaces having a vertebral endplate contacting area in the range of 0.1 square inches to 0.5 square inches.
  38. 38. The instrument of claim 37, wherein said shaft defines an inflation lumen in communication with said inflatable portion.
  39. 39. The instrument of claim 37, wherein each of said vertebral endplate contacting surfaces has an oval shape.
  40. 40. The instrument of claim 37, wherein each of said vertebral endplate contacting surfaces has a circular shape.
  41. 41. The instrument of claim 37, wherein each of said vertebral endplate contacting surfaces has a generally rectangular shape.
  42. 42. The instrument of claim 37, wherein each of said vertebral endplate contacting surfaces has a first contacting node and a second contacting node and said inflatable portion includes a concave surface extending between said first and second contacting nodes.
  43. 43. The instrument of claim 42, wherein when in said inflated configuration said inflatable portion is sized to contact vertebral endplates adjacent the disc space and restore the disc space to a desired disc space height, said inflatable portion is further sized and shaped in the anterior, posterior and lateral directions to occupy the disc space with a void formed between the inflatable portion and an inner wall of an annulus surrounding the disc space annulus.
  44. 44. A spinal surgical device implantable in a disc space, comprising:
    a shaft extending between a proximal end and a distal end; and
    an inflatable portion adjacent said distal end, said inflatable portion having a reduced size configuration for insertion into the disc space and an enlarged inflated configuration, wherein when in said inflated configuration said inflatable portion is sized to contact vertebral endplates adjacent the disc space and restore the disc space to a desired disc space height, said inflatable portion is further sized and shaped in the anterior, posterior and lateral directions to occupy the disc space with a void formed between the inflatable portion and an inner wall of an annulus surrounding the disc space annulus; and
    a first material in the void.
  45. 45. The device of claim 44, wherein said shape is selected from the group consisting of: a vertically-oriented cylinder, a horizontally-oriented cylinder, a sphere, a center cylinder with frusto-conically tapered ends, a banana, and a pear.
  46. 46. The device of claim 44, wherein when inflated said inflatable portion defines an upper vertebral endplate contacting surface and an opposite lower vertebral endplate contacting surface, each of said upper and lower vertebral endplate contacting surfaces having a vertebral endplate contacting area in the range of 0.1 square inches to 0.5 square inches.
  47. 47. The device of claim 44, wherein said shaft defines an inflation lumen in communication with said inflatable portion.
US09918332 2001-07-30 2001-07-30 Methods and devices for interbody spinal stabilization Abandoned US20030028251A1 (en)

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US10706789 US20040106999A1 (en) 2001-07-30 2003-11-12 Methods and devices for interbody spinal stabilization

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US09918332 US20030028251A1 (en) 2001-07-30 2001-07-30 Methods and devices for interbody spinal stabilization
CA 2455826 CA2455826A1 (en) 2001-07-30 2002-06-24 Methods and devices for interbody spinal stablization
PCT/US2002/019921 WO2003011147A1 (en) 2001-07-30 2002-06-24 Methods and devices for interbody spinal stablization
JP2003516385A JP4299125B2 (en) 2001-07-30 2002-06-24 Interbody spinal stabilization method and apparatus
EP20020742275 EP1414353A1 (en) 2001-07-30 2002-06-24 Methods and devices for interbody spinal stablization
US10706789 US20040106999A1 (en) 2001-07-30 2003-11-12 Methods and devices for interbody spinal stabilization
US11363122 US20060149279A1 (en) 2001-07-30 2006-02-27 Methods and devices for interbody spinal stabilization
US12287390 US20090043345A1 (en) 2001-07-30 2008-10-09 Methods and devices for interbody spinal stabilization
US13081072 US8221460B2 (en) 2001-07-30 2011-04-06 Methods and devices for interbody spinal stabilization

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US11363122 Abandoned US20060149279A1 (en) 2001-07-30 2006-02-27 Methods and devices for interbody spinal stabilization
US12287390 Abandoned US20090043345A1 (en) 2001-07-30 2008-10-09 Methods and devices for interbody spinal stabilization
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US12287390 Abandoned US20090043345A1 (en) 2001-07-30 2008-10-09 Methods and devices for interbody spinal stabilization
US13081072 Active US8221460B2 (en) 2001-07-30 2011-04-06 Methods and devices for interbody spinal stabilization

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US20110184422A1 (en) 2011-07-28 application
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