JP2006504441A5 - - Google Patents
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- JP2006504441A5 JP2006504441A5 JP2003526883A JP2003526883A JP2006504441A5 JP 2006504441 A5 JP2006504441 A5 JP 2006504441A5 JP 2003526883 A JP2003526883 A JP 2003526883A JP 2003526883 A JP2003526883 A JP 2003526883A JP 2006504441 A5 JP2006504441 A5 JP 2006504441A5
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- JP
- Japan
- Prior art keywords
- medical device
- substance
- agent
- group
- drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000126 substance Substances 0.000 claims 56
- 230000001225 therapeutic effect Effects 0.000 claims 17
- 239000011248 coating agent Substances 0.000 claims 15
- 238000000576 coating method Methods 0.000 claims 15
- 239000002260 anti-inflammatory agent Substances 0.000 claims 14
- 229940124599 anti-inflammatory drug Drugs 0.000 claims 14
- 239000003146 anticoagulant agent Substances 0.000 claims 14
- 229920000642 polymer Polymers 0.000 claims 11
- 230000002792 vascular Effects 0.000 claims 10
- 230000000702 anti-platelet effect Effects 0.000 claims 9
- 230000001028 anti-proliverative effect Effects 0.000 claims 9
- 229940002612 prodrug Drugs 0.000 claims 9
- 239000000651 prodrug Substances 0.000 claims 9
- 150000003839 salts Chemical class 0.000 claims 9
- 230000002927 anti-mitotic effect Effects 0.000 claims 8
- 239000003080 antimitotic agent Substances 0.000 claims 8
- 239000003524 antilipemic agent Substances 0.000 claims 7
- 229940121386 matrix metalloproteinase inhibitor Drugs 0.000 claims 7
- 239000003771 matrix metalloproteinase inhibitor Substances 0.000 claims 7
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 claims 5
- 102000019034 Chemokines Human genes 0.000 claims 5
- 108010012236 Chemokines Proteins 0.000 claims 5
- 102000004127 Cytokines Human genes 0.000 claims 5
- 108090000695 Cytokines Proteins 0.000 claims 5
- 229940127217 antithrombotic drug Drugs 0.000 claims 5
- 239000000824 cytostatic agent Substances 0.000 claims 5
- 239000002254 cytotoxic agent Substances 0.000 claims 5
- 229940127089 cytotoxic agent Drugs 0.000 claims 5
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 claims 5
- 229960003957 dexamethasone Drugs 0.000 claims 5
- 238000012377 drug delivery Methods 0.000 claims 5
- 229960005309 estradiol Drugs 0.000 claims 5
- 229930182833 estradiol Natural products 0.000 claims 5
- 239000003527 fibrinolytic agent Substances 0.000 claims 5
- 239000003112 inhibitor Substances 0.000 claims 5
- 230000002093 peripheral effect Effects 0.000 claims 5
- 229960000103 thrombolytic agent Drugs 0.000 claims 5
- 229940122803 Vinca alkaloid Drugs 0.000 claims 4
- 229940100198 alkylating agent Drugs 0.000 claims 4
- 239000002168 alkylating agent Substances 0.000 claims 4
- 230000001085 cytostatic effect Effects 0.000 claims 4
- 239000002207 metabolite Substances 0.000 claims 4
- 230000010118 platelet activation Effects 0.000 claims 4
- 208000010110 spontaneous platelet aggregation Diseases 0.000 claims 4
- 230000007348 cell dedifferentiation Effects 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 230000004069 differentiation Effects 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- YMTINGFKWWXKFG-UHFFFAOYSA-N fenofibrate Chemical compound C1=CC(OC(C)(C)C(=O)OC(C)C)=CC=C1C(=O)C1=CC=C(Cl)C=C1 YMTINGFKWWXKFG-UHFFFAOYSA-N 0.000 claims 2
- 229960002297 fenofibrate Drugs 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- 0 C[C@](C[C@](CC[C@@]1[n]2nnnc2)C[C@]1OC)[C@](CC([C@](C)C=C(C)[C@]([C@](C([C@](C)C[C@](C)C=CC=CC=C(C)[C@@](*)C[C@](CC[C@@]1C)O[C@@]1(C)C(C(N1[C@]2CCCC1)=O)=O)=O)OC)O)=O)OC2=O Chemical compound C[C@](C[C@](CC[C@@]1[n]2nnnc2)C[C@]1OC)[C@](CC([C@](C)C=C(C)[C@]([C@](C([C@](C)C[C@](C)C=CC=CC=C(C)[C@@](*)C[C@](CC[C@@]1C)O[C@@]1(C)C(C(N1[C@]2CCCC1)=O)=O)=O)OC)O)=O)OC2=O 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/950,307 US6890546B2 (en) | 1998-09-24 | 2001-09-10 | Medical devices containing rapamycin analogs |
| US10/235,572 US20030129215A1 (en) | 1998-09-24 | 2002-09-06 | Medical devices containing rapamycin analogs |
| PCT/US2002/028776 WO2003022807A2 (en) | 2001-09-10 | 2002-09-10 | Medical devices containing rapamycin analogs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006504441A JP2006504441A (ja) | 2006-02-09 |
| JP2006504441A5 true JP2006504441A5 (enExample) | 2009-01-22 |
Family
ID=29714851
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003526883A Pending JP2006504441A (ja) | 2001-09-10 | 2002-09-10 | ラパマイシン類似体を含む医療装置 |
Country Status (10)
| Country | Link |
|---|---|
| US (6) | US20030129215A1 (enExample) |
| EP (2) | EP1578705B1 (enExample) |
| JP (1) | JP2006504441A (enExample) |
| CN (2) | CN101564571B (enExample) |
| AT (1) | ATE476401T1 (enExample) |
| BR (1) | BRPI0212433A8 (enExample) |
| CA (1) | CA2460074C (enExample) |
| DE (1) | DE60237241D1 (enExample) |
| PL (1) | PL374776A1 (enExample) |
| WO (1) | WO2003022807A2 (enExample) |
Families Citing this family (92)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060198867A1 (en) * | 1997-09-25 | 2006-09-07 | Abbott Laboratories, Inc. | Compositions and methods of administering rapamycin analogs using medical devices for long-term efficacy |
| US7399480B2 (en) * | 1997-09-26 | 2008-07-15 | Abbott Laboratories | Methods of administering tetrazole-containing rapamycin analogs with other therapeutic substances using medical devices |
| US20030129215A1 (en) * | 1998-09-24 | 2003-07-10 | T-Ram, Inc. | Medical devices containing rapamycin analogs |
| US6890546B2 (en) * | 1998-09-24 | 2005-05-10 | Abbott Laboratories | Medical devices containing rapamycin analogs |
| US7357942B2 (en) * | 1997-09-26 | 2008-04-15 | Abbott Laboratories | Compositions, systems, and kits for administering zotarolimus and paclitaxel to blood vessel lumens |
| US7378105B2 (en) * | 1997-09-26 | 2008-05-27 | Abbott Laboratories | Drug delivery systems, kits, and methods for administering zotarolimus and paclitaxel to blood vessel lumens |
| US8257726B2 (en) * | 1997-09-26 | 2012-09-04 | Abbott Laboratories | Compositions, systems, kits, and methods of administering rapamycin analogs with paclitaxel using medical devices |
| US8394398B2 (en) * | 1997-09-26 | 2013-03-12 | Abbott Laboratories | Methods of administering rapamycin analogs with anti-inflammatories using medical devices |
| US8257725B2 (en) * | 1997-09-26 | 2012-09-04 | Abbott Laboratories | Delivery of highly lipophilic agents via medical devices |
| US8057816B2 (en) * | 1997-09-26 | 2011-11-15 | Abbott Laboratories | Compositions and methods of administering paclitaxel with other drugs using medical devices |
| US7455853B2 (en) * | 1998-09-24 | 2008-11-25 | Abbott Cardiovascular Systems Inc. | Medical devices containing rapamycin analogs |
| US8257724B2 (en) * | 1998-09-24 | 2012-09-04 | Abbott Laboratories | Delivery of highly lipophilic agents via medical devices |
| US20060240070A1 (en) * | 1998-09-24 | 2006-10-26 | Cromack Keith R | Delivery of highly lipophilic agents via medical devices |
| US20070032853A1 (en) | 2002-03-27 | 2007-02-08 | Hossainy Syed F | 40-O-(2-hydroxy)ethyl-rapamycin coated stent |
| US20040018228A1 (en) | 2000-11-06 | 2004-01-29 | Afmedica, Inc. | Compositions and methods for reducing scar tissue formation |
| US7651695B2 (en) * | 2001-05-18 | 2010-01-26 | Advanced Cardiovascular Systems, Inc. | Medicated stents for the treatment of vascular disease |
| US20080145402A1 (en) * | 2001-09-10 | 2008-06-19 | Abbott Cardiovascular Systems Inc. | Medical Devices Containing Rapamycin Analogs |
| US7264822B2 (en) * | 2002-04-03 | 2007-09-04 | Poly-Med, Inc. | Conjugated drug-polymer coated stent |
| EP1536850B1 (en) * | 2002-09-06 | 2016-08-10 | Abbott Laboratories | Medical device having hydration inhibitor |
| EP1572029B1 (en) | 2002-11-07 | 2010-03-24 | Abbott Laboratories | Method of loading beneficial agent to a prosthesis by fluid-jet application |
| US20090093875A1 (en) * | 2007-05-01 | 2009-04-09 | Abbott Laboratories | Drug eluting stents with prolonged local elution profiles with high local concentrations and low systemic concentrations |
| US8088404B2 (en) * | 2003-03-20 | 2012-01-03 | Medtronic Vasular, Inc. | Biocompatible controlled release coatings for medical devices and related methods |
| DK1638624T3 (da) * | 2003-06-19 | 2014-02-03 | Vascular Therapies Llc | Vaskulær lukkeindretning |
| WO2005005434A1 (en) * | 2003-07-08 | 2005-01-20 | Novartis Ag | Use of rapamycin and rapamycin derivatives for the treatment of bone loss |
| EP1656163B1 (en) * | 2003-08-13 | 2014-08-06 | Poly-Med, Inc. | Biocompatible controlled release coatings for medical devices and related methods |
| US8828416B2 (en) * | 2004-03-09 | 2014-09-09 | Cordis Corporation | Local vascular delivery of topotecan in combination with rapamycin to prevent restenosis following vascular injury |
| US20070027523A1 (en) * | 2004-03-19 | 2007-02-01 | Toner John L | Method of treating vascular disease at a bifurcated vessel using coated balloon |
| JP4949227B2 (ja) * | 2004-03-19 | 2012-06-06 | アボット・ラボラトリーズ | バルーンおよびプロテーゼからの多剤送達 |
| US8431145B2 (en) | 2004-03-19 | 2013-04-30 | Abbott Laboratories | Multiple drug delivery from a balloon and a prosthesis |
| US20100030183A1 (en) * | 2004-03-19 | 2010-02-04 | Toner John L | Method of treating vascular disease at a bifurcated vessel using a coated balloon |
| US8551512B2 (en) * | 2004-03-22 | 2013-10-08 | Advanced Cardiovascular Systems, Inc. | Polyethylene glycol/poly(butylene terephthalate) copolymer coated devices including EVEROLIMUS |
| US8709469B2 (en) * | 2004-06-30 | 2014-04-29 | Abbott Cardiovascular Systems Inc. | Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device |
| US7901451B2 (en) * | 2004-09-24 | 2011-03-08 | Biosensors International Group, Ltd. | Drug-delivery endovascular stent and method for treating restenosis |
| US20100021455A1 (en) * | 2004-12-08 | 2010-01-28 | Cedars-Sinai Medical Center | Methods for diagnosis and treatment of crohn's disease |
| WO2008101133A2 (en) * | 2007-02-14 | 2008-08-21 | Cedars-Sinai Medical Center | Methods of using genes and genetic variants to predict or diagnose inflammatory bowel disease |
| WO2006102359A2 (en) * | 2005-03-23 | 2006-09-28 | Abbott Laboratories | Delivery of highly lipophilic agents via medical devices |
| TWI455713B (zh) * | 2005-03-23 | 2014-10-11 | Abbott Lab | 使用醫藥裝置投予雷帕霉素(rapamycin)類似物以達長期功效之方法及組合物 |
| WO2007032777A2 (en) | 2005-03-23 | 2007-03-22 | Abbott Laboratories | Compositions and methods of administering rapamycin analogs using medical devices for long-term efficacy |
| CA2601864A1 (en) * | 2005-04-08 | 2006-10-19 | Surmodics, Inc. | Sustained release implants and methods for subretinal delivery of bioactive agents to treat or prevent retinal disease |
| US8778375B2 (en) * | 2005-04-29 | 2014-07-15 | Advanced Cardiovascular Systems, Inc. | Amorphous poly(D,L-lactide) coating |
| US20080214595A1 (en) * | 2005-05-16 | 2008-09-04 | Seigo Izumo | Use Of Rapamycin Derivatives For The Treatment And/Or Prevention Of Cardiovas Cular Disorders |
| US8021679B2 (en) * | 2005-08-25 | 2011-09-20 | Medtronic Vascular, Inc | Nitric oxide-releasing biodegradable polymers useful as medical devices and coatings therefore |
| JP2009505726A (ja) * | 2005-08-25 | 2009-02-12 | メドトロニック ヴァスキュラー インコーポレイテッド | 生分解性ポリマーを含むことにより向上した官能性を有する医療機器及びコーティング |
| JP5285426B2 (ja) * | 2005-10-14 | 2013-09-11 | アボット ラボラトリーズ | 医療デバイスを用いて、パクリタキセルとともにラパマイシン類似体を投与することについての組成物、システム、キット及び方法 |
| CA2633768A1 (en) * | 2005-11-10 | 2007-05-18 | Bayer Schering Pharma Aktiengesellschaft | Reduction of restenosis |
| US7700614B2 (en) * | 2005-12-14 | 2010-04-20 | Abbott Laboratories | One pot synthesis of tetrazole derivatives of rapamycin |
| US20070142905A1 (en) * | 2005-12-16 | 2007-06-21 | Medtronic Vascular, Inc. | Medical devices to treat or inhibit restenosis |
| BRPI0600275A (pt) * | 2006-01-03 | 2007-10-02 | Brz Biotecnologia Ltda | prótese coronária liberadora de composição medicamentosa para prevenção e tratamento da reestenose e processo de fabricação |
| BRPI0600285C1 (pt) * | 2006-01-13 | 2011-10-11 | Brz Biotecnologia Ltda | compostos farmacêuticos contendo nanopartìculas úteis para tratamento de lesões reestenóticas |
| US20080003254A1 (en) * | 2006-05-23 | 2008-01-03 | Abbott Laboratories | Systems and methods for delivering a rapamycin analog that do not inhibit human coronary artery endothelial cell migration |
| US20090258028A1 (en) * | 2006-06-05 | 2009-10-15 | Abbott Cardiovascular Systems Inc. | Methods Of Forming Coatings For Implantable Medical Devices For Controlled Release Of A Peptide And A Hydrophobic Drug |
| US8323676B2 (en) * | 2008-06-30 | 2012-12-04 | Abbott Cardiovascular Systems Inc. | Poly(ester-amide) and poly(amide) coatings for implantable medical devices for controlled release of a protein or peptide and a hydrophobic drug |
| US7812032B2 (en) * | 2006-07-25 | 2010-10-12 | Abbott Laboratories | Crystalline forms of rapamycin analogs |
| US7820812B2 (en) * | 2006-07-25 | 2010-10-26 | Abbott Laboratories | Methods of manufacturing crystalline forms of rapamycin analogs |
| WO2008014222A1 (en) * | 2006-07-25 | 2008-01-31 | Abbott Laboratories | Crystalline forms of rapamycin analogs |
| CN101557814B (zh) * | 2006-09-13 | 2015-05-20 | 万能医药公司 | 大环内酯化合物及它们的使用方法 |
| US10695327B2 (en) | 2006-09-13 | 2020-06-30 | Elixir Medical Corporation | Macrocyclic lactone compounds and methods for their use |
| EP2068911A4 (en) * | 2006-09-13 | 2011-08-03 | Arca Biopharma Inc | METHOD FOR THE TREATMENT OF CANCER |
| US8088789B2 (en) * | 2006-09-13 | 2012-01-03 | Elixir Medical Corporation | Macrocyclic lactone compounds and methods for their use |
| WO2008106451A2 (en) * | 2007-02-26 | 2008-09-04 | Cedars-Sinai Medical Center | Methods of using single nucleotide polymorphisms in the tl1a gene to predict or diagnose inflammatory bowel disease |
| WO2010039931A2 (en) * | 2008-10-01 | 2010-04-08 | Cedars-Sinai Medical Center | Methods of using il17rd and il23-il17 pathway genes to diagnose crohn's disease |
| US20100015156A1 (en) * | 2007-03-06 | 2010-01-21 | Cedars-Sinai Medical Center | Diagnosis of inflammatory bowel disease in children |
| WO2008116150A2 (en) | 2007-03-21 | 2008-09-25 | Cedars-Sinai Medical Center | Ileal pouch-anal anastomosis (ipaa) factors in the treatment of inflammatory bowel disease |
| WO2008134569A2 (en) * | 2007-04-26 | 2008-11-06 | Cedars-Sinai Medical Center | Diagnosis and treatment of inflammatory bowel disease in the puerto rican population |
| US20100144903A1 (en) * | 2007-05-04 | 2010-06-10 | Cedars-Sinai Medical Center | Methods of diagnosis and treatment of crohn's disease |
| US8690823B2 (en) | 2007-07-13 | 2014-04-08 | Abbott Cardiovascular Systems Inc. | Drug coated balloon catheter |
| US8617114B2 (en) * | 2007-07-13 | 2013-12-31 | Abbott Cardiovascular Systems Inc. | Drug coated balloon catheter |
| US8765162B2 (en) * | 2008-06-30 | 2014-07-01 | Abbott Cardiovascular Systems Inc. | Poly(amide) and poly(ester-amide) polymers and drug delivery particles and coatings containing same |
| US20100047319A1 (en) * | 2008-08-21 | 2010-02-25 | Michael Huy Ngo | Biodegradable Poly(Ester-Amide) And Poly(Amide) Coatings For Implantable Medical Devices With Enhanced Bioabsorption Times |
| US8092822B2 (en) | 2008-09-29 | 2012-01-10 | Abbott Cardiovascular Systems Inc. | Coatings including dexamethasone derivatives and analogs and olimus drugs |
| US20110189685A1 (en) * | 2008-10-22 | 2011-08-04 | Cedars-Sinai Medical Center | Methods of using jak3 genetic variants to diagnose and predict crohn's disease |
| US20110229471A1 (en) | 2008-11-26 | 2011-09-22 | Cedars-Sinai Medical Center | Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease |
| AU2009321621B2 (en) | 2008-12-02 | 2013-06-13 | Biocompatibles Uk Limited | Pancreatic tumour treatment |
| CA2746124A1 (en) * | 2008-12-11 | 2010-06-17 | The Governors Of The University Of Alberta | Methods and systems for inducing immunologic tolerance to non-self antigens |
| US9580752B2 (en) | 2008-12-24 | 2017-02-28 | Cedars-Sinai Medical Center | Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy |
| CN104622599B (zh) | 2009-05-18 | 2017-04-12 | 纽姆克斯股份有限公司 | 细长的肺减容装置在部署过程中的横截面变化 |
| US20100324645A1 (en) * | 2009-06-17 | 2010-12-23 | John Stankus | Drug coated balloon catheter and pharmacokinetic profile |
| US8828474B2 (en) * | 2009-09-20 | 2014-09-09 | Medtronic Vascular, Inc. | Apparatus and methods for loading a drug eluting medical device |
| US8951595B2 (en) * | 2009-12-11 | 2015-02-10 | Abbott Cardiovascular Systems Inc. | Coatings with tunable molecular architecture for drug-coated balloon |
| US8480620B2 (en) * | 2009-12-11 | 2013-07-09 | Abbott Cardiovascular Systems Inc. | Coatings with tunable solubility profile for drug-coated balloon |
| US20110144577A1 (en) * | 2009-12-11 | 2011-06-16 | John Stankus | Hydrophilic coatings with tunable composition for drug coated balloon |
| US8389041B2 (en) | 2010-06-17 | 2013-03-05 | Abbott Cardiovascular Systems, Inc. | Systems and methods for rotating and coating an implantable device |
| US8632846B2 (en) * | 2010-09-17 | 2014-01-21 | Medtronic Vascular, Inc. | Apparatus and methods for loading a drug eluting medical device |
| CN101947350A (zh) * | 2010-10-27 | 2011-01-19 | 上海硕创生物医药科技有限公司 | 一种偏心中空式球囊导管 |
| EP3639841B1 (en) | 2013-03-27 | 2023-09-06 | Cedars-Sinai Medical Center | Treating fibrosis by inhibiting tl1a |
| EP3022295A4 (en) | 2013-07-19 | 2017-03-01 | Cedars-Sinai Medical Center | Signature of tl1a (tnfsf15) signaling pathway |
| US10517892B2 (en) | 2013-10-22 | 2019-12-31 | Medtronic Minimed, Inc. | Methods and systems for inhibiting foreign-body responses in diabetic patients |
| ES2923782T3 (es) | 2015-12-02 | 2022-09-30 | Memorial Sloan Kettering Cancer Center | Oncoterapia dirigida al receptor celular del virus del Valle de Séneca (SVV) |
| JP7082945B2 (ja) | 2016-03-17 | 2022-06-09 | シーダーズ―シナイ メディカル センター | Rnaset2により炎症性腸疾患を診断する方法 |
| CN105943209A (zh) * | 2016-06-08 | 2016-09-21 | 葛晨亮 | 新型药物涂层球囊 |
| CN108187212B (zh) * | 2018-03-14 | 2022-07-15 | 董鹏 | 一种药物球囊 |
| CN114146231A (zh) * | 2020-09-07 | 2022-03-08 | 上海鸿脉医疗科技有限公司 | 药物球囊及其制备方法 |
Family Cites Families (145)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA737247B (en) | 1972-09-29 | 1975-04-30 | Ayerst Mckenna & Harrison | Rapamycin and process of preparation |
| US3993749A (en) | 1974-04-12 | 1976-11-23 | Ayerst Mckenna And Harrison Ltd. | Rapamycin and process of preparation |
| US4885171A (en) | 1978-11-03 | 1989-12-05 | American Home Products Corporation | Use of rapamycin in treatment of certain tumors |
| US4316885A (en) | 1980-08-25 | 1982-02-23 | Ayerst, Mckenna And Harrison, Inc. | Acyl derivatives of rapamycin |
| US4401653A (en) | 1981-03-09 | 1983-08-30 | Ayerst, Mckenna & Harrison Inc. | Combination of rapamycin and picibanil for the treatment of tumors |
| US4894366A (en) | 1984-12-03 | 1990-01-16 | Fujisawa Pharmaceutical Company, Ltd. | Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same |
| US4650803A (en) | 1985-12-06 | 1987-03-17 | University Of Kansas | Prodrugs of rapamycin |
| US5527337A (en) | 1987-06-25 | 1996-06-18 | Duke University | Bioabsorbable stent and method of making the same |
| US4916193A (en) * | 1987-12-17 | 1990-04-10 | Allied-Signal Inc. | Medical devices fabricated totally or in part from copolymers of recurring units derived from cyclic carbonates and lactides |
| US5283201A (en) * | 1988-05-17 | 1994-02-01 | Advanced Power Technology, Inc. | High density power device fabrication process |
| US5092877A (en) * | 1988-09-01 | 1992-03-03 | Corvita Corporation | Radially expandable endoprosthesis |
| US4994071A (en) * | 1989-05-22 | 1991-02-19 | Cordis Corporation | Bifurcating stent apparatus and method |
| US5304121A (en) * | 1990-12-28 | 1994-04-19 | Boston Scientific Corporation | Drug delivery system making use of a hydrogel polymer coating |
| US5202750A (en) * | 1990-04-09 | 1993-04-13 | U.S. Philips Corp. | MOS-gated thyristor |
| AU7998091A (en) * | 1990-05-17 | 1991-12-10 | Harbor Medical Devices, Inc. | Medical device polymer |
| JPH04230389A (ja) | 1990-07-16 | 1992-08-19 | American Home Prod Corp | ラパマイシン誘導体 |
| US5023262A (en) | 1990-08-14 | 1991-06-11 | American Home Products Corporation | Hydrogenated rapamycin derivatives |
| US5163952A (en) * | 1990-09-14 | 1992-11-17 | Michael Froix | Expandable polymeric stent with memory and delivery apparatus and method |
| US6248129B1 (en) * | 1990-09-14 | 2001-06-19 | Quanam Medical Corporation | Expandable polymeric stent with memory and delivery apparatus and method |
| PT98990A (pt) | 1990-09-19 | 1992-08-31 | American Home Prod | Processo para a preparacao de esteres de acidos carboxilicos de rapamicina |
| US5120842A (en) | 1991-04-01 | 1992-06-09 | American Home Products Corporation | Silyl ethers of rapamycin |
| US5120725A (en) | 1991-05-29 | 1992-06-09 | American Home Products Corporation | Bicyclic rapamycins |
| US5120727A (en) | 1991-05-29 | 1992-06-09 | American Home Products Corporation | Rapamycin dimers |
| US6090901A (en) * | 1991-07-05 | 2000-07-18 | Biocompatibles Limited | Polymeric surface coatings |
| US5705583A (en) * | 1991-07-05 | 1998-01-06 | Biocompatibles Limited | Polymeric surface coatings |
| US5457111A (en) | 1991-09-05 | 1995-10-10 | Abbott Laboratories | Macrocyclic immunomodulators |
| US5516781A (en) * | 1992-01-09 | 1996-05-14 | American Home Products Corporation | Method of treating restenosis with rapamycin |
| US5177203A (en) | 1992-03-05 | 1993-01-05 | American Home Products Corporation | Rapamycin 42-sulfonates and 42-(N-carboalkoxy) sulfamates useful as immunosuppressive agents |
| KR100284210B1 (ko) * | 1992-04-28 | 2001-03-02 | 이건 이. 버그 | 과증식성 혈관 질환 치료용 배합 제제 |
| US5283456A (en) * | 1992-06-17 | 1994-02-01 | International Business Machines Corporation | Vertical gate transistor with low temperature epitaxial channel |
| ZA935111B (en) * | 1992-07-17 | 1994-02-04 | Smithkline Beecham Corp | Rapamycin derivatives |
| US5449382A (en) * | 1992-11-04 | 1995-09-12 | Dayton; Michael P. | Minimally invasive bioactivated endoprosthesis for vessel repair |
| US5260300A (en) * | 1992-11-19 | 1993-11-09 | American Home Products Corporation | Rapamycin carbonate esters as immuno-suppressant agents |
| US5324673A (en) * | 1992-11-19 | 1994-06-28 | Motorola, Inc. | Method of formation of vertical transistor |
| US5322802A (en) * | 1993-01-25 | 1994-06-21 | North Carolina State University At Raleigh | Method of fabricating silicon carbide field effect transistor |
| EP0689465A1 (en) * | 1993-03-18 | 1996-01-03 | Cedars-Sinai Medical Center | Drug incorporating and releasing polymeric coating for bioprosthesis |
| US5824048A (en) * | 1993-04-26 | 1998-10-20 | Medtronic, Inc. | Method for delivering a therapeutic substance to a body lumen |
| US5464650A (en) * | 1993-04-26 | 1995-11-07 | Medtronic, Inc. | Intravascular stent and method |
| US5380299A (en) * | 1993-08-30 | 1995-01-10 | Med Institute, Inc. | Thrombolytic treated intravascular medical device |
| JPH07122749A (ja) * | 1993-09-01 | 1995-05-12 | Toshiba Corp | 半導体装置及びその製造方法 |
| US5527907A (en) * | 1993-11-19 | 1996-06-18 | Abbott Laboratories | Macrolide immunomodulators |
| JP4105761B2 (ja) * | 1993-11-19 | 2008-06-25 | アボット・ラボラトリーズ | ラパミシン(マクロライド)の半合成類似体免疫調節剤 |
| KR0141218B1 (ko) * | 1993-11-24 | 1998-07-15 | 윤종용 | 고집적 반도체장치의 제조방법 |
| US5641694A (en) * | 1994-12-22 | 1997-06-24 | International Business Machines Corporation | Method of fabricating vertical epitaxial SOI transistor |
| FR2730231B1 (fr) * | 1995-02-02 | 1997-04-04 | Fournier Sca Lab | Association de fenofibrate et de vitamine e, utilisation en therapeutique |
| US5605696A (en) * | 1995-03-30 | 1997-02-25 | Advanced Cardiovascular Systems, Inc. | Drug loaded polymeric material and method of manufacture |
| US6099562A (en) * | 1996-06-13 | 2000-08-08 | Schneider (Usa) Inc. | Drug coating with topcoat |
| US6120536A (en) * | 1995-04-19 | 2000-09-19 | Schneider (Usa) Inc. | Medical devices with long term non-thrombogenic coatings |
| US5837313A (en) * | 1995-04-19 | 1998-11-17 | Schneider (Usa) Inc | Drug release stent coating process |
| US5869079A (en) * | 1995-06-02 | 1999-02-09 | Oculex Pharmaceuticals, Inc. | Formulation for controlled release of drugs by combining hydrophilic and hydrophobic agents |
| CA2178541C (en) * | 1995-06-07 | 2009-11-24 | Neal E. Fearnot | Implantable medical device |
| US5609629A (en) * | 1995-06-07 | 1997-03-11 | Med Institute, Inc. | Coated implantable medical device |
| US5637898A (en) * | 1995-12-22 | 1997-06-10 | North Carolina State University | Vertical field effect transistors having improved breakdown voltage capability and low on-state resistance |
| GB9606452D0 (en) * | 1996-03-27 | 1996-06-05 | Sandoz Ltd | Organic compounds |
| DE69714994T2 (de) * | 1996-06-04 | 2003-04-30 | Cook Inc., Bloomington | Implantierbares medizinisches gerät |
| NZ333657A (en) * | 1996-07-30 | 2000-05-26 | Novartis Ag | A pharmaceutical composition comprising cyclosporin A and 40-O-(2-hydroxyethyl)-rapamycin |
| US6495579B1 (en) * | 1996-12-02 | 2002-12-17 | Angiotech Pharmaceuticals, Inc. | Method for treating multiple sclerosis |
| CA2256323C (en) | 1997-03-31 | 2007-05-22 | Kabushikikaisha Igaki Iryo Sekkei | Stent for vessel |
| US6240616B1 (en) * | 1997-04-15 | 2001-06-05 | Advanced Cardiovascular Systems, Inc. | Method of manufacturing a medicated porous metal prosthesis |
| US5843172A (en) * | 1997-04-15 | 1998-12-01 | Advanced Cardiovascular Systems, Inc. | Porous medicated stent |
| EP0913416B1 (en) * | 1997-04-17 | 2005-10-19 | Toyobo Co., Ltd. | Biocompatible polymers |
| US6273913B1 (en) * | 1997-04-18 | 2001-08-14 | Cordis Corporation | Modified stent useful for delivery of drugs along stent strut |
| US6890546B2 (en) * | 1998-09-24 | 2005-05-10 | Abbott Laboratories | Medical devices containing rapamycin analogs |
| US20060198867A1 (en) * | 1997-09-25 | 2006-09-07 | Abbott Laboratories, Inc. | Compositions and methods of administering rapamycin analogs using medical devices for long-term efficacy |
| US6015815A (en) * | 1997-09-26 | 2000-01-18 | Abbott Laboratories | Tetrazole-containing rapamycin analogs with shortened half-lives |
| US20030129215A1 (en) * | 1998-09-24 | 2003-07-10 | T-Ram, Inc. | Medical devices containing rapamycin analogs |
| US7378105B2 (en) * | 1997-09-26 | 2008-05-27 | Abbott Laboratories | Drug delivery systems, kits, and methods for administering zotarolimus and paclitaxel to blood vessel lumens |
| US8394398B2 (en) * | 1997-09-26 | 2013-03-12 | Abbott Laboratories | Methods of administering rapamycin analogs with anti-inflammatories using medical devices |
| US8257726B2 (en) * | 1997-09-26 | 2012-09-04 | Abbott Laboratories | Compositions, systems, kits, and methods of administering rapamycin analogs with paclitaxel using medical devices |
| TW557297B (en) * | 1997-09-26 | 2003-10-11 | Abbott Lab | Rapamycin analogs having immunomodulatory activity, and pharmaceutical compositions containing same |
| US6623521B2 (en) * | 1998-02-17 | 2003-09-23 | Md3, Inc. | Expandable stent with sliding and locking radial elements |
| US6096726A (en) * | 1998-03-11 | 2000-08-01 | Surface Solutions Laboratories Incorporated | Multicomponent complex for use with substrate |
| AU749623B2 (en) * | 1998-03-26 | 2002-06-27 | Astellas Pharma Inc. | Sustained release preparations |
| AU3212199A (en) * | 1998-03-31 | 1999-10-18 | Scimed Life Systems, Inc. | Temperature controlled solute delivery system |
| US20010029351A1 (en) * | 1998-04-16 | 2001-10-11 | Robert Falotico | Drug combinations and delivery devices for the prevention and treatment of vascular disease |
| US8029561B1 (en) * | 2000-05-12 | 2011-10-04 | Cordis Corporation | Drug combination useful for prevention of restenosis |
| ATE466603T1 (de) * | 1998-04-27 | 2010-05-15 | Surmodics Inc | Bioaktive wirkstoffe freisetzende beschichtungen |
| US6225165B1 (en) * | 1998-05-13 | 2001-05-01 | Micron Technology, Inc. | High density SRAM cell with latched vertical transistors |
| US6104045A (en) * | 1998-05-13 | 2000-08-15 | Micron Technology, Inc. | High density planar SRAM cell using bipolar latch-up and gated diode breakdown |
| US6280411B1 (en) * | 1998-05-18 | 2001-08-28 | Scimed Life Systems, Inc. | Localized delivery of drug agents |
| US6229161B1 (en) * | 1998-06-05 | 2001-05-08 | Stanford University | Semiconductor capacitively-coupled NDR device and its applications in high-density high-speed memories and in power switches |
| US6153252A (en) * | 1998-06-30 | 2000-11-28 | Ethicon, Inc. | Process for coating stents |
| CA2340652C (en) * | 1998-08-20 | 2013-09-24 | Cook Incorporated | Coated implantable medical device comprising paclitaxel |
| US6335029B1 (en) * | 1998-08-28 | 2002-01-01 | Scimed Life Systems, Inc. | Polymeric coatings for controlled delivery of active agents |
| US6033562A (en) * | 1998-08-28 | 2000-03-07 | Budeit; Donald A | Apparatus for aerating wastewater from pressurized or gravity flow sources |
| US7455853B2 (en) * | 1998-09-24 | 2008-11-25 | Abbott Cardiovascular Systems Inc. | Medical devices containing rapamycin analogs |
| US7662409B2 (en) * | 1998-09-25 | 2010-02-16 | Gel-Del Technologies, Inc. | Protein matrix materials, devices and methods of making and using thereof |
| US6187024B1 (en) * | 1998-11-10 | 2001-02-13 | Target Therapeutics, Inc. | Bioactive coating for vaso-occlusive devices |
| US6419692B1 (en) * | 1999-02-03 | 2002-07-16 | Scimed Life Systems, Inc. | Surface protection method for stents and balloon catheters for drug delivery |
| US6368658B1 (en) * | 1999-04-19 | 2002-04-09 | Scimed Life Systems, Inc. | Coating medical devices using air suspension |
| US6730349B2 (en) * | 1999-04-19 | 2004-05-04 | Scimed Life Systems, Inc. | Mechanical and acoustical suspension coating of medical implants |
| US6607598B2 (en) * | 1999-04-19 | 2003-08-19 | Scimed Life Systems, Inc. | Device for protecting medical devices during a coating process |
| WO2001001957A1 (en) * | 1999-05-27 | 2001-01-11 | Biocompatibles Limited | Local drug delivery |
| US6258121B1 (en) * | 1999-07-02 | 2001-07-10 | Scimed Life Systems, Inc. | Stent coating |
| US6077733A (en) * | 1999-09-03 | 2000-06-20 | Taiwan Semiconductor Manufacturing Company | Method of manufacturing self-aligned T-shaped gate through dual damascene |
| US6713119B2 (en) * | 1999-09-03 | 2004-03-30 | Advanced Cardiovascular Systems, Inc. | Biocompatible coating for a prosthesis and a method of forming the same |
| US6663606B1 (en) * | 1999-10-28 | 2003-12-16 | Scimed Life Systems, Inc. | Biocompatible medical devices |
| AU2623201A (en) * | 1999-12-30 | 2001-07-16 | Kam W Leong | Controlled delivery of therapeutic agents by insertable medical devices |
| SE0000363L (sv) * | 2000-02-04 | 2001-08-05 | Zoucas Kirurgkonsult Ab | Belagd medicinsk anordning |
| WO2001063416A1 (en) * | 2000-02-24 | 2001-08-30 | Bops Incorporated | Methods and apparatus for scalable array processor interrupt detection and response |
| US20020013616A1 (en) * | 2000-05-05 | 2002-01-31 | Andrew Carter | Multilayer stents having enhanced flexibility and hoop strength |
| US20020007213A1 (en) * | 2000-05-19 | 2002-01-17 | Robert Falotico | Drug/drug delivery systems for the prevention and treatment of vascular disease |
| US20020007215A1 (en) * | 2000-05-19 | 2002-01-17 | Robert Falotico | Drug/drug delivery systems for the prevention and treatment of vascular disease |
| US20020005206A1 (en) * | 2000-05-19 | 2002-01-17 | Robert Falotico | Antiproliferative drug and delivery device |
| US6776796B2 (en) * | 2000-05-12 | 2004-08-17 | Cordis Corportation | Antiinflammatory drug and delivery device |
| US20020007214A1 (en) * | 2000-05-19 | 2002-01-17 | Robert Falotico | Drug/drug delivery systems for the prevention and treatment of vascular disease |
| CA2409003C (en) * | 2000-05-16 | 2010-10-19 | Ortho-Mcneil Pharmaceutical, Inc. | Process for coating medical devices using super-critical carbon dioxide |
| US6974473B2 (en) * | 2000-06-30 | 2005-12-13 | Vascular Architects, Inc. | Function-enhanced thrombolytic AV fistula and method |
| US20020077693A1 (en) * | 2000-12-19 | 2002-06-20 | Barclay Bruce J. | Covered, coiled drug delivery stent and method |
| US6506408B1 (en) * | 2000-07-13 | 2003-01-14 | Scimed Life Systems, Inc. | Implantable or insertable therapeutic agent delivery device |
| US6746773B2 (en) * | 2000-09-29 | 2004-06-08 | Ethicon, Inc. | Coatings for medical devices |
| AU9486901A (en) * | 2000-09-29 | 2002-04-08 | Cordis Corp | Coated medical devices |
| US7261735B2 (en) * | 2001-05-07 | 2007-08-28 | Cordis Corporation | Local drug delivery devices and methods for maintaining the drug coatings thereon |
| AU1129902A (en) * | 2000-09-29 | 2002-04-08 | Cordis Corp | Coated medical devices |
| US6758859B1 (en) * | 2000-10-30 | 2004-07-06 | Kenny L. Dang | Increased drug-loading and reduced stress drug delivery device |
| CA2425665C (en) * | 2000-10-31 | 2013-07-16 | Cook Incorporated | Coated implantable medical device |
| US6517888B1 (en) * | 2000-11-28 | 2003-02-11 | Scimed Life Systems, Inc. | Method for manufacturing a medical device having a coated portion by laser ablation |
| US6545097B2 (en) * | 2000-12-12 | 2003-04-08 | Scimed Life Systems, Inc. | Drug delivery compositions and medical devices containing block copolymer |
| WO2002056790A2 (en) * | 2000-12-22 | 2002-07-25 | Avantec Vascular Corporation | Delivery of therapeutic capable agents |
| GB0100760D0 (en) * | 2001-01-11 | 2001-02-21 | Biocompatibles Ltd | Drug delivery from stents |
| EP2314293B1 (en) * | 2001-01-16 | 2017-01-04 | Vascular Therapies, LLC | Implantable device containing resorbable matrix material and rapamycin for preventing or treating vasuloproliferative diseases |
| US6752829B2 (en) * | 2001-01-30 | 2004-06-22 | Scimed Life Systems, Inc. | Stent with channel(s) for containing and delivering a biologically active material and method for manufacturing the same |
| DE10107795B4 (de) * | 2001-02-13 | 2014-05-15 | Berlex Ag | Gefäßstütze mit einem Grundkörper, Verfahren zur Herstellung der Gefäßstütze, Vorrichtung zur Beschichtung der Gefäßstütze |
| US20020119178A1 (en) * | 2001-02-23 | 2002-08-29 | Luc Levesque | Drug eluting device for treating vascular diseases |
| US20020127263A1 (en) * | 2001-02-27 | 2002-09-12 | Wenda Carlyle | Peroxisome proliferator-acitvated receptor gamma ligand eluting medical device |
| US6462359B1 (en) * | 2001-03-22 | 2002-10-08 | T-Ram, Inc. | Stability in thyristor-based memory device |
| US6780424B2 (en) * | 2001-03-30 | 2004-08-24 | Charles David Claude | Controlled morphologies in polymer drug for release of drugs from polymer films |
| US6787179B2 (en) * | 2001-06-29 | 2004-09-07 | Ethicon, Inc. | Sterilization of bioactive coatings |
| EP1273314A1 (en) * | 2001-07-06 | 2003-01-08 | Terumo Kabushiki Kaisha | Stent |
| US6805703B2 (en) * | 2001-09-18 | 2004-10-19 | Scimed Life Systems, Inc. | Protective membrane for reconfiguring a workpiece |
| US6669980B2 (en) * | 2001-09-18 | 2003-12-30 | Scimed Life Systems, Inc. | Method for spray-coating medical devices |
| US7195640B2 (en) * | 2001-09-25 | 2007-03-27 | Cordis Corporation | Coated medical devices for the treatment of vulnerable plaque |
| US7033389B2 (en) * | 2001-10-16 | 2006-04-25 | Scimed Life Systems, Inc. | Tubular prosthesis for external agent delivery |
| US6764709B2 (en) * | 2001-11-08 | 2004-07-20 | Scimed Life Systems, Inc. | Method for making and measuring a coating on the surface of a medical device using an ultraviolet laser |
| US6517889B1 (en) * | 2001-11-26 | 2003-02-11 | Swaminathan Jayaraman | Process for coating a surface of a stent |
| US7014654B2 (en) * | 2001-11-30 | 2006-03-21 | Scimed Life Systems, Inc. | Stent designed for the delivery of therapeutic substance or other agents |
| US6945994B2 (en) * | 2001-12-05 | 2005-09-20 | Boston Scientific Scimed, Inc. | Combined balloon-expanding and self-expanding stent |
| BR0306858A (pt) * | 2002-01-10 | 2004-11-03 | Novartis Ag | Sistemas de liberação de drogas para a prevenção e tratamento de doenças vasculares compreendendo rapamicina e derivados da mesma |
| US6743463B2 (en) * | 2002-03-28 | 2004-06-01 | Scimed Life Systems, Inc. | Method for spray-coating a medical device having a tubular wall such as a stent |
| US20030204168A1 (en) * | 2002-04-30 | 2003-10-30 | Gjalt Bosma | Coated vascular devices |
| US7754238B2 (en) * | 2002-05-03 | 2010-07-13 | Avi Biopharma, Inc. | Delivery of microparticle-conjugated drugs for inhibition of stenosis |
| US7396539B1 (en) * | 2002-06-21 | 2008-07-08 | Advanced Cardiovascular Systems, Inc. | Stent coatings with engineered drug release rate |
| US20050019404A1 (en) * | 2003-06-30 | 2005-01-27 | Hsing-Wen Sung | Drug-eluting biodegradable stent |
| US6945995B2 (en) * | 2002-08-29 | 2005-09-20 | Boston Scientific Scimed, Inc. | Stent overlap point markers |
| US7302690B2 (en) * | 2003-07-31 | 2007-11-27 | International Business Machines Corporation | Method and apparatus for transparently sharing an exception vector between firmware and an operating system |
-
2002
- 2002-09-06 US US10/235,572 patent/US20030129215A1/en not_active Abandoned
- 2002-09-10 CA CA2460074A patent/CA2460074C/en not_active Expired - Lifetime
- 2002-09-10 EP EP02766269A patent/EP1578705B1/en not_active Expired - Lifetime
- 2002-09-10 PL PL02374776A patent/PL374776A1/xx not_active Application Discontinuation
- 2002-09-10 AT AT02766269T patent/ATE476401T1/de not_active IP Right Cessation
- 2002-09-10 CN CN200910126573.8A patent/CN101564571B/zh not_active Expired - Lifetime
- 2002-09-10 CN CNB028217527A patent/CN100548236C/zh not_active Expired - Lifetime
- 2002-09-10 JP JP2003526883A patent/JP2006504441A/ja active Pending
- 2002-09-10 WO PCT/US2002/028776 patent/WO2003022807A2/en not_active Ceased
- 2002-09-10 EP EP10166508.1A patent/EP2255836B1/en not_active Expired - Lifetime
- 2002-09-10 BR BRPI0212433A patent/BRPI0212433A8/pt not_active Application Discontinuation
- 2002-09-10 DE DE60237241T patent/DE60237241D1/de not_active Expired - Lifetime
-
2006
- 2006-04-25 US US11/411,734 patent/US20060198870A1/en not_active Abandoned
- 2006-10-12 US US12/090,253 patent/US20090162413A1/en not_active Abandoned
-
2008
- 2008-03-07 US US12/044,677 patent/US20080153790A1/en not_active Abandoned
- 2008-10-21 US US12/255,605 patent/US20090047324A1/en not_active Abandoned
- 2008-10-21 US US12/255,603 patent/US20090047323A1/en not_active Abandoned
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