JP2006502219A5 - - Google Patents
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- Publication number
- JP2006502219A5 JP2006502219A5 JP2004543136A JP2004543136A JP2006502219A5 JP 2006502219 A5 JP2006502219 A5 JP 2006502219A5 JP 2004543136 A JP2004543136 A JP 2004543136A JP 2004543136 A JP2004543136 A JP 2004543136A JP 2006502219 A5 JP2006502219 A5 JP 2006502219A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- alkyl
- hydrogen
- aryl
- heteroaryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41788902P | 2002-10-11 | 2002-10-11 | |
| PCT/US2003/031413 WO2004032840A2 (en) | 2002-10-11 | 2003-10-02 | Compounds, compositions, and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006502219A JP2006502219A (ja) | 2006-01-19 |
| JP2006502219A5 true JP2006502219A5 (https=) | 2006-11-02 |
Family
ID=32094113
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004543136A Pending JP2006502219A (ja) | 2002-10-11 | 2003-10-02 | 化合物、組成物および方法 |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7476743B2 (https=) |
| EP (1) | EP1558588A4 (https=) |
| JP (1) | JP2006502219A (https=) |
| KR (1) | KR20050075356A (https=) |
| CN (1) | CN1726198A (https=) |
| AR (1) | AR044193A1 (https=) |
| AU (1) | AU2003282665A1 (https=) |
| BR (1) | BR0315247A (https=) |
| CA (1) | CA2501938A1 (https=) |
| IL (1) | IL167936A0 (https=) |
| IS (1) | IS7798A (https=) |
| MX (1) | MXPA05003830A (https=) |
| NO (1) | NO20052267L (https=) |
| NZ (1) | NZ539643A (https=) |
| PL (1) | PL375889A1 (https=) |
| RU (1) | RU2005114491A (https=) |
| TW (1) | TW200418818A (https=) |
| WO (1) | WO2004032840A2 (https=) |
| ZA (1) | ZA200503733B (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0510929A (pt) * | 2004-06-18 | 2007-07-17 | Chiron Corp | derivados de n-(1-(1-benzil-4-fenil-1h-imidazol-2-il)-2,2-dimetilpropil) benzamida e compostos relacionados como inibidores de proteìna de eixo de kinesin (ksp) para o tratamento de cáncer |
| EP1781674A1 (en) | 2004-08-18 | 2007-05-09 | AstraZeneca AB | Enantiomers of selected fused pyrimidones and uses in the treatment and prevention of cancer |
| DE102006023337A1 (de) * | 2006-05-18 | 2007-11-22 | Merck Patent Gmbh | Triazolderivate II |
| JP5343363B2 (ja) * | 2008-01-31 | 2013-11-13 | アイシン精機株式会社 | シートクッション調整装置 |
| CN101643451B (zh) * | 2008-08-07 | 2013-03-06 | 浙江海正药业股份有限公司 | 过氧化物酶增殖物激活受体亚型δ类激动剂化合物及其制备方法 |
| EA201201404A1 (ru) | 2010-04-15 | 2013-04-30 | Новартис Аг | Триазолы как ингибиторы кбв (кинезин-белок веретена) |
| WO2012095691A1 (en) * | 2011-01-15 | 2012-07-19 | Jubilant Life Sciences Ltd. | An improved process for producing aminopyridines |
| EP2822931B1 (en) | 2012-03-09 | 2017-05-03 | Inception 2, Inc. | Triazolone compounds and uses thereof |
| SG11201504622PA (en) | 2012-12-20 | 2015-07-30 | Inception 2 Inc | Triazolone compounds and uses thereof |
| CN105579440A (zh) | 2013-09-06 | 2016-05-11 | 因森普深2公司 | 三唑酮化合物及其应用 |
| JP6971858B2 (ja) | 2015-06-22 | 2021-11-24 | バイエル ファーマ アクチエンゲゼルシャフト | 酵素開裂性基を有する抗体薬物複合体（ａｄｃ）および抗体プロドラッグ複合体（ａｐｄｃ） |
| TW201722958A (zh) * | 2015-09-15 | 2017-07-01 | 葛蘭素史克智慧財產（第二）有限公司 | 化學化合物 |
| CN110312534B (zh) | 2016-12-21 | 2023-04-04 | 拜耳制药股份公司 | 具有酶促可裂解基团的抗体-药物-缀合物(adc) |
| US20250215039A1 (en) * | 2022-03-30 | 2025-07-03 | Primefour Therapeutics, Inc. | Nucleosides for treating cancer |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE793532A (fr) * | 1971-12-29 | 1973-06-29 | Upjohn Co | Nouvelles 1,2,4-triazol-3-ones et leur preparation |
| US3748339A (en) * | 1972-05-05 | 1973-07-24 | Upjohn Co | 2-(3-(1-(dimethylamino)alkyl)-1,5-dihydro-5-oxo - 1 - substituted-4h-1,2,4-triazol-4-yl)benzophenone and process |
| IT1068010B (it) * | 1976-11-17 | 1985-03-21 | Montedison Spa | Nuovi esteri fosforici derivati dall' 1-2-4 triazolo ad azione insetticida,nematocida e acaricida e loro preparazione |
| NL7712430A (nl) * | 1976-11-17 | 1978-05-19 | Montedison Spa | Nieuwe fosforzuuresters, afgeleid van 1.2.4- -triazool, met een insecticide, nematocide en acaricide werking en werkwijze ter bereiding daarvan. |
| US4487773A (en) * | 1981-03-16 | 1984-12-11 | Mead Johnson & Company | 1,2,4-Triazol-3-one antidepressants |
| US5250558A (en) * | 1992-01-28 | 1993-10-05 | Merck & Co., Inc. | Substituted triazolinones, triazolinethiones, and triazolinimines as neurotensin antagonists used to treat psychosis |
| GB9211193D0 (en) | 1992-05-27 | 1992-07-08 | Merck Sharp & Dohme | Therapeutic agents |
| IL106142A (en) * | 1992-06-29 | 1997-03-18 | Merck & Co Inc | Morpholine and thiomorpholine tachykinin receptor antagonists, their preparation and pharmaceutical compositions containing them |
| AU722883B2 (en) * | 1995-10-18 | 2000-08-10 | Merck & Co., Inc. | Cyclopentyl tachykinin receptor antagonists |
| JP2002234874A (ja) * | 2000-09-26 | 2002-08-23 | Tanabe Seiyaku Co Ltd | ５−フェニルベンジルアミン誘導体、その製法及びその合成中間体 |
| US6727244B2 (en) * | 2000-10-26 | 2004-04-27 | Merck & Co., Inc. | Mammalian metabolites of a tachykinin receptor antagonist |
| EP1515724B1 (en) * | 2002-06-14 | 2009-10-21 | Merck & Co., Inc. | Mitotic kinesin inhibitors |
-
2003
- 2003-10-02 BR BR0315247-2A patent/BR0315247A/pt not_active IP Right Cessation
- 2003-10-02 EP EP03774548A patent/EP1558588A4/en not_active Withdrawn
- 2003-10-02 RU RU2005114491/04A patent/RU2005114491A/ru not_active Application Discontinuation
- 2003-10-02 AU AU2003282665A patent/AU2003282665A1/en not_active Abandoned
- 2003-10-02 MX MXPA05003830A patent/MXPA05003830A/es unknown
- 2003-10-02 CN CNA200380105737XA patent/CN1726198A/zh active Pending
- 2003-10-02 NZ NZ539643A patent/NZ539643A/en unknown
- 2003-10-02 KR KR1020057006260A patent/KR20050075356A/ko not_active Withdrawn
- 2003-10-02 CA CA002501938A patent/CA2501938A1/en not_active Abandoned
- 2003-10-02 PL PL03375889A patent/PL375889A1/xx unknown
- 2003-10-02 WO PCT/US2003/031413 patent/WO2004032840A2/en not_active Ceased
- 2003-10-02 US US10/529,634 patent/US7476743B2/en not_active Expired - Fee Related
- 2003-10-02 JP JP2004543136A patent/JP2006502219A/ja active Pending
- 2003-10-09 AR ARP030103684A patent/AR044193A1/es unknown
- 2003-10-09 TW TW092128029A patent/TW200418818A/zh unknown
-
2005
- 2005-04-10 IL IL167936A patent/IL167936A0/en unknown
- 2005-04-11 IS IS7798A patent/IS7798A/is unknown
- 2005-05-10 NO NO20052267A patent/NO20052267L/no not_active Application Discontinuation
- 2005-05-10 ZA ZA200503733A patent/ZA200503733B/en unknown