JP2006501312A5 - - Google Patents
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- Publication number
- JP2006501312A5 JP2006501312A5 JP2005501778A JP2005501778A JP2006501312A5 JP 2006501312 A5 JP2006501312 A5 JP 2006501312A5 JP 2005501778 A JP2005501778 A JP 2005501778A JP 2005501778 A JP2005501778 A JP 2005501778A JP 2006501312 A5 JP2006501312 A5 JP 2006501312A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- compound
- compound according
- hydrogen
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40546702P | 2002-08-23 | 2002-08-23 | |
| US41783702P | 2002-10-11 | 2002-10-11 | |
| US47137303P | 2003-05-15 | 2003-05-15 | |
| PCT/US2003/026478 WO2004018463A2 (en) | 2002-08-23 | 2003-08-22 | Pyridyl substituted heterocycles useful for treating or preventing hcv infection |
| US10/646,348 US7157473B2 (en) | 2002-08-23 | 2003-08-22 | Pyridyl substituted heterocycles useful for treating or preventing HCV infection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006501312A JP2006501312A (ja) | 2006-01-12 |
| JP2006501312A5 true JP2006501312A5 (https=) | 2006-09-28 |
Family
ID=31950772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005501778A Pending JP2006501312A (ja) | 2002-08-23 | 2003-08-22 | Hcv感染を治療または予防するのに有用なピリジル置換複素環 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US7157473B2 (https=) |
| EP (1) | EP1530569A2 (https=) |
| JP (1) | JP2006501312A (https=) |
| KR (1) | KR20050033653A (https=) |
| AU (1) | AU2003262831A1 (https=) |
| BR (1) | BR0313755A (https=) |
| CA (1) | CA2494164A1 (https=) |
| HR (1) | HRP20050168A2 (https=) |
| IL (1) | IL166639A0 (https=) |
| MX (1) | MXPA05002082A (https=) |
| NO (1) | NO20051404L (https=) |
| NZ (1) | NZ537980A (https=) |
| PL (1) | PL374536A1 (https=) |
| RS (1) | RS20050175A (https=) |
| WO (1) | WO2004018463A2 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY151199A (en) | 2001-11-02 | 2014-04-30 | Rigel Pharmaceuticals Inc | Substituted diphenyl heterocycles useful for treating hcv infection |
| HRP20050168A2 (en) * | 2002-08-23 | 2005-10-31 | Rigel Pharmaceuticals | Pyridyl substituted heterocycles useful for treating or preventing hcv infection |
| US7115642B2 (en) | 2003-05-02 | 2006-10-03 | Rigel Pharmaceuticals, Inc. | Substituted diphenyl isoxazoles, pyrazoles and oxadiazoles useful for treating HCV infection |
| US7326790B2 (en) * | 2003-05-02 | 2008-02-05 | Rigel Pharmaceuticals, Inc. | Diphenylisoxazole compounds and hydro isomers thereof |
| US7220745B2 (en) | 2003-05-15 | 2007-05-22 | Rigel Pharmaceuticals | Heterocyclic compounds useful to treat HCV |
| US20050075309A1 (en) | 2003-07-25 | 2005-04-07 | Richard Storer | Purine nucleoside analogues for treating Flaviviridae including hepatitis C |
| WO2005049065A2 (en) * | 2003-11-19 | 2005-06-02 | Rigel Pharmaceuticals, Inc. | Synergistic combinations of dihaloacetamide with interferon or ribavirin for treatment hcv infections |
| JP2007514763A (ja) * | 2003-12-19 | 2007-06-07 | ライジェル ファーマシューティカルズ, インコーポレイテッド | C型肝炎ウイルス(hcv)の感染を処置するための組成物および方法 |
| US7514434B2 (en) | 2004-02-23 | 2009-04-07 | Rigel Pharmaceuticals, Inc. | Heterocyclic compounds having an oxadiazole moiety and hydro isomers thereof |
| JP2007530582A (ja) * | 2004-03-26 | 2007-11-01 | ライジェル ファーマシューティカルズ, インコーポレイテッド | 代謝可能部分を含む複素環抗ウイルス化合物およびその使用 |
| JP2008540425A (ja) * | 2005-05-02 | 2008-11-20 | ライジェル ファーマシューティカルズ, インコーポレイテッド | 代謝可能部分を含む複素環式抗ウイルス性化合物およびその使用 |
| US8267868B2 (en) * | 2005-08-10 | 2012-09-18 | C. R. Bard, Inc. | Single-insertion, multiple sample biopsy device with integrated markers |
| KR100890862B1 (ko) * | 2005-11-07 | 2009-03-27 | 주식회사 엘지화학 | 유기 발광 소자 및 이의 제조 방법 |
| RU2487131C2 (ru) * | 2008-03-14 | 2013-07-10 | Оцука Фармасьютикал Ко., Лтд. | Ингибитор ммр-2 и/или ммр-9 |
| US8362020B2 (en) * | 2009-12-30 | 2013-01-29 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| AU2016281346B2 (en) | 2015-06-23 | 2020-01-02 | Kissei Pharmaceutical Co., Ltd. | Pyrazole derivative, or pharmaceutically acceptable salt thereof |
| CN116535399B (zh) * | 2022-01-25 | 2024-02-27 | 中国药科大学 | 3-羟基-5-(异噁唑-5-基)吡啶甲酰甘氨酸类化合物、制法、药物组合物和应用 |
| IL326496A (en) * | 2023-08-17 | 2026-04-01 | Sanofi Sa | Pyridyl imidazoles – their preparation and therapeutic application |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2852503A (en) * | 1953-12-31 | 1958-09-16 | American Cyanamid Co | 2, 5-bis (p-aminophenyl) furan azo derivatives |
| NL242505A (https=) * | 1958-08-20 | |||
| US3335149A (en) * | 1963-08-21 | 1967-08-08 | Monsanto Co | Thiazole diamines |
| FR1459375A (fr) | 1965-10-20 | 1966-04-29 | Westinghouse Electric Corp | Copolymères linéaires oxadiazole-imide |
| SU508198A3 (ru) | 1971-07-22 | 1976-03-25 | Группо Лепетит С.П.А. (Фирма) | Способ получени производных 1,2,4-триазола |
| DE2137719A1 (de) | 1971-07-28 | 1973-02-08 | Basf Ag | Verfahren zur herstellung von aminobenzonitrilen |
| US3964896A (en) * | 1971-08-09 | 1976-06-22 | Uniroyal, Inc. | Oxadiazole benzoic acid derivatives as herbicides |
| US3853893A (en) * | 1973-04-02 | 1974-12-10 | Squibb & Sons Inc | Anthelmintic 5-(pyridyl)-3-(isothiocyanophenyl) oxadiazoles |
| DE2721955A1 (de) | 1977-05-14 | 1978-11-23 | Basf Ag | Azofarbstoffe |
| DE3623302A1 (de) * | 1985-11-09 | 1987-05-14 | Bayer Ag | Nicotinsaeurederivate |
| DE4016049A1 (de) * | 1990-05-18 | 1991-11-21 | Basf Ag | 3-isoxazolylbenzylester, ihre herstellung und ihre verwendung |
| JPH04124178A (ja) | 1990-09-12 | 1992-04-24 | Sds Biotech Kk | 複素環式化合物および該化合物を含有する除草剤 |
| DE4124942A1 (de) * | 1991-07-27 | 1993-01-28 | Thomae Gmbh Dr K | 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE4137940A1 (de) * | 1991-11-18 | 1993-05-19 | Basf Ag | 3-isoxazolylphenylverbindungen, ihre herstellung und ihre verwendung |
| WO1993017671A1 (en) | 1992-03-06 | 1993-09-16 | Statens Seruminstitut | Treatment and prophylaxis of diseases caused by parasites, or bacteria |
| DE4210502A1 (de) | 1992-03-31 | 1993-10-07 | Bayer Ag | Verwendung von 3-aminosubstituierten Isoxazolderivaten zur Bekämpfung von Endoparasiten, neue 3-aminosubstituierte Isoxazolderivate und Verfahren zu ihrer Herstellung |
| WO1994017059A1 (fr) | 1993-01-29 | 1994-08-04 | Nippon Soda Co., Ltd. | Derive heterocyclique |
| DE4408084A1 (de) | 1994-03-10 | 1995-09-14 | Hoechst Ag | 3,5-Disubstituierte und 3,4,5-trisubstituierte 2-Isoxazoline und Isoxazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| AU3087195A (en) | 1994-08-02 | 1996-03-04 | Nippon Soda Co., Ltd. | Oxazole derivative, process for producing the same, and herbicide |
| DK0808312T3 (da) * | 1995-02-02 | 2001-02-12 | Smithkline Beecham Plc | Indolderivater som 5-HT-receptorantagonist |
| DE19643037A1 (de) | 1996-10-18 | 1998-04-23 | Boehringer Ingelheim Kg | Neue Oxadiazole, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel |
| US20020035156A1 (en) * | 1997-04-18 | 2002-03-21 | Barbara Roniker | Combination therapy in the prevention of cardiovascular disorders |
| EE200300169A (et) | 1997-04-18 | 2003-06-16 | G.D. Searle & Co. | Tsüklooksügenaas-2 inhibiitorite kasutamise meetod südame-veresoonkonna haiguste ärahoidmiseks |
| EP0927992A4 (en) | 1997-07-17 | 1999-09-15 | Sony Corp | MAGNETIC RECORDING MEDIUM AND MAGNETIC RECORDING / REPRODUCING DEVICE COMPRISING SAME |
| EP1025857A4 (en) | 1997-10-22 | 2003-11-12 | Eisai Co Ltd | RETINOIC ACID AGONISTS, PREVENTIVE AND THERAPEUTIC AGENTS FOR NEPHRITES |
| DE19860802A1 (de) | 1998-12-30 | 2000-10-26 | Virgene Pharmaceuticals Ag | Herstellung eines Mittels gegen Hepatitis B-, HI-, Paramyxo und Orthomyxo-Viren |
| DE19904389A1 (de) | 1999-02-04 | 2000-08-10 | Bayer Ag | Verwendung von substituierten Isoxazolcarbonsäuren und Derivate und neue Stoffe |
| DE60033028T2 (de) | 1999-04-23 | 2007-11-15 | Takeda Pharmaceutical Co. Ltd. | 5-pyridyl-1,3-azol-derivate, verfahren zu ihrer herstellung und ihre verwendung |
| GB2351081A (en) | 1999-06-18 | 2000-12-20 | Lilly Forschung Gmbh | Pharmaceutically active imidazoline compounds and analogues thereof |
| DE10032874A1 (de) | 2000-07-06 | 2002-01-17 | Bayer Ag | Arzneimittelkombinationen gegen virale Erkrankungen |
| WO2001074811A2 (en) | 2000-03-30 | 2001-10-11 | Takeda Chemical Industries, Ltd. | Substituted 1,3-thiazole compounds, their production and use |
| AU4890301A (en) * | 2000-04-17 | 2001-10-30 | Dong Wha Pharmaceutical Industrial Co., Ltd. | 6-methylnicotinamide derivatives as antiviral agents |
| US6579880B2 (en) * | 2000-06-06 | 2003-06-17 | Ortho-Mcneil Pharmaceutical, Inc. | Isoxazoles and oxadiazoles as anti-inflammatory inhibitors of IL-8 |
| GB0017676D0 (en) * | 2000-07-19 | 2000-09-06 | Angeletti P Ist Richerche Bio | Inhibitors of viral polymerase |
| WO2002020436A2 (en) | 2000-09-05 | 2002-03-14 | Neogenesis Pharmaceuticals, Inc. | Methods for forming combinatorial libraries combining amide bond formation with epoxide opening |
| CA2431171A1 (en) | 2000-12-08 | 2002-06-13 | Takeda Chemical Industries, Ltd. | Substituted thiazole derivatives bearing 3-pyridyl groups, process for preparing the same and use thereof |
| JP4368582B2 (ja) | 2001-01-13 | 2009-11-18 | ユニバーシティ オブ ノース カロライナ アット チャペル ヒル | 牛ウイルス性下痢ウイルス(bvdv)感染およびc型肝炎ウイルス(hcv)感染を処置するのに有用な化合物、方法、および組成物 |
| RU2003133750A (ru) * | 2001-04-19 | 2005-05-10 | Байер АГ (DE) | Арилсульфонамиды в качестве антивирусных агентов |
| DE10148598A1 (de) | 2001-04-19 | 2002-10-24 | Bayer Ag | Neue Arylsulfonamide als antivirale Mittel |
| JP4303109B2 (ja) | 2001-10-04 | 2009-07-29 | メルク エンド カムパニー インコーポレーテッド | 代謝共役型グルタミン酸受容体−5のヘテロアリール置換テトラゾール調節剤 |
| MY151199A (en) | 2001-11-02 | 2014-04-30 | Rigel Pharmaceuticals Inc | Substituted diphenyl heterocycles useful for treating hcv infection |
| HRP20050168A2 (en) * | 2002-08-23 | 2005-10-31 | Rigel Pharmaceuticals | Pyridyl substituted heterocycles useful for treating or preventing hcv infection |
| US7220745B2 (en) | 2003-05-15 | 2007-05-22 | Rigel Pharmaceuticals | Heterocyclic compounds useful to treat HCV |
-
2003
- 2003-08-22 HR HR20050168A patent/HRP20050168A2/hr not_active Application Discontinuation
- 2003-08-22 JP JP2005501778A patent/JP2006501312A/ja active Pending
- 2003-08-22 US US10/646,348 patent/US7157473B2/en not_active Expired - Lifetime
- 2003-08-22 AU AU2003262831A patent/AU2003262831A1/en not_active Abandoned
- 2003-08-22 MX MXPA05002082A patent/MXPA05002082A/es unknown
- 2003-08-22 CA CA002494164A patent/CA2494164A1/en not_active Abandoned
- 2003-08-22 NZ NZ537980A patent/NZ537980A/en not_active IP Right Cessation
- 2003-08-22 PL PL03374536A patent/PL374536A1/xx not_active Application Discontinuation
- 2003-08-22 EP EP03793349A patent/EP1530569A2/en not_active Withdrawn
- 2003-08-22 WO PCT/US2003/026478 patent/WO2004018463A2/en not_active Ceased
- 2003-08-22 KR KR1020057003019A patent/KR20050033653A/ko not_active Ceased
- 2003-08-22 BR BR0313755-4A patent/BR0313755A/pt not_active IP Right Cessation
- 2003-08-22 RS YUP-2005/0175A patent/RS20050175A/sr unknown
-
2005
- 2005-02-01 IL IL16663905A patent/IL166639A0/xx unknown
- 2005-03-17 NO NO20051404A patent/NO20051404L/no not_active Application Discontinuation
-
2006
- 2006-11-21 US US11/561,991 patent/US7332602B2/en not_active Expired - Lifetime
-
2007
- 2007-12-20 US US11/960,990 patent/US7714137B2/en not_active Expired - Fee Related
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