JP2006328074A5 - - Google Patents
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- JP2006328074A5 JP2006328074A5 JP2006171517A JP2006171517A JP2006328074A5 JP 2006328074 A5 JP2006328074 A5 JP 2006328074A5 JP 2006171517 A JP2006171517 A JP 2006171517A JP 2006171517 A JP2006171517 A JP 2006171517A JP 2006328074 A5 JP2006328074 A5 JP 2006328074A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- disease
- amino acid
- igf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11501099P | 1999-01-06 | 1999-01-06 | |
| US17026199P | 1999-12-09 | 1999-12-09 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000592321A Division JP3971108B2 (ja) | 1999-01-06 | 2000-01-05 | インシュリン様成長因子（ｉｇｆ）ｉ突然変異体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006328074A JP2006328074A (ja) | 2006-12-07 |
| JP2006328074A5 true JP2006328074A5 (cg-RX-API-DMAC10.html) | 2010-09-09 |
Family
ID=26812755
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000592321A Expired - Lifetime JP3971108B2 (ja) | 1999-01-06 | 2000-01-05 | インシュリン様成長因子（ｉｇｆ）ｉ突然変異体 |
| JP2006171517A Pending JP2006328074A (ja) | 1999-01-06 | 2006-06-21 | インシュリン様成長因子（ｉｇｆ）ｉ突然変異体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000592321A Expired - Lifetime JP3971108B2 (ja) | 1999-01-06 | 2000-01-05 | インシュリン様成長因子（ｉｇｆ）ｉ突然変異体 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US6403764B1 (cg-RX-API-DMAC10.html) |
| EP (1) | EP1141014B1 (cg-RX-API-DMAC10.html) |
| JP (2) | JP3971108B2 (cg-RX-API-DMAC10.html) |
| AT (1) | ATE284415T1 (cg-RX-API-DMAC10.html) |
| AU (1) | AU762351B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2356109C (cg-RX-API-DMAC10.html) |
| DE (1) | DE60016560T2 (cg-RX-API-DMAC10.html) |
| DK (1) | DK1141014T3 (cg-RX-API-DMAC10.html) |
| ES (1) | ES2234560T3 (cg-RX-API-DMAC10.html) |
| IL (2) | IL143866A0 (cg-RX-API-DMAC10.html) |
| PT (1) | PT1141014E (cg-RX-API-DMAC10.html) |
| WO (1) | WO2000040613A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6875741B2 (en) * | 1998-09-02 | 2005-04-05 | Renuka Pillutla | Insulin and IGF-1 receptor agonists and antagonists |
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| US20020143725A1 (en) * | 2001-01-29 | 2002-10-03 | Smith Robin Young | Systems, methods and computer program products for determining parameters for chemical synthesis and for supplying the reagents, equipment and/or chemicals synthesized thereby |
| US7250950B2 (en) * | 2001-01-29 | 2007-07-31 | Symyx Technologies, Inc. | Systems, methods and computer program products for determining parameters for chemical synthesis |
| US6849718B2 (en) * | 2001-03-20 | 2005-02-01 | Dana Farber Cancer Institute, Inc. | Muteins of hypoxia inducible factor alpha and methods of use thereof |
| US20040048925A1 (en) * | 2002-09-09 | 2004-03-11 | Wiley David B. | Composition and method for enhancing the bioavailability of calcium and magnesium in dietary supplements and food additives |
| TWI353991B (en) | 2003-05-06 | 2011-12-11 | Syntonix Pharmaceuticals Inc | Immunoglobulin chimeric monomer-dimer hybrids |
| WO2005047327A2 (en) | 2003-11-12 | 2005-05-26 | Biogen Idec Ma Inc. | NEONATAL Fc RECEPTOR (FcRn)-BINDING POLYPEPTIDE VARIANTS, DIMERIC Fc BINDING PROTEINS AND METHODS RELATED THERETO |
| US7833513B2 (en) | 2004-12-03 | 2010-11-16 | Rhode Island Hospital | Treatment of Alzheimer's Disease |
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| MY146381A (en) * | 2004-12-22 | 2012-08-15 | Amgen Inc | Compositions and methods relating relating to anti-igf-1 receptor antibodies |
| CA2593212A1 (en) | 2005-01-05 | 2006-07-13 | Biogen Idec Ma Inc. | Cripto binding molecules |
| AU2006203882B2 (en) | 2005-01-07 | 2011-05-12 | Regeneron Pharmaceuticals, Inc. | IGF-1 fusion polypeptides and therapeutic uses thereof |
| TWI406870B (zh) | 2005-02-21 | 2013-09-01 | Chugai Pharmaceutical Co Ltd | A method of making a protein using hamster IGF-1 |
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| BRPI0715754A2 (pt) * | 2006-08-31 | 2013-07-09 | Hoffmann La Roche | mÉtodo para a produÇço de fator do crescimento similar Á insulina i |
| CL2007002502A1 (es) | 2006-08-31 | 2008-05-30 | Hoffmann La Roche | Variantes del factor de crecimiento similar a insulina-1 humano (igf-1) pegilados en lisina; metodo de produccion; proteina de fusion que la comprende; y su uso para tratar la enfermedad de alzheimer. |
| DK2115477T3 (en) * | 2007-01-25 | 2015-08-10 | Hoffmann La Roche | USE OF IGFBP-7 IN THE EVIDENCE OF HEART FAILURE |
| ES2707551T3 (es) * | 2007-03-02 | 2019-04-04 | Amgen Inc | Métodos y composiciones para tratar enfermedades tumorales |
| BRPI0812768A2 (pt) * | 2007-06-08 | 2014-12-02 | Massachusetts Inst Technology | Igf para o tratamento de síndrome de rett e transtornos sinápticos. |
| WO2009121759A2 (en) * | 2008-04-03 | 2009-10-08 | F. Hoffmann-La Roche Ag | Use of pegylated igf-i variants for the treatment of neuromuscular disorders |
| US20110045510A1 (en) * | 2008-04-03 | 2011-02-24 | Kurt Lang | Pegylated insulin-like-growth-factor assay |
| PL219335B1 (pl) * | 2008-07-04 | 2015-04-30 | Inst Biotechnologii I Antybiotyków | Pochodna insuliny lub jej farmaceutycznie dopuszczalna sól, jej zastosowanie oraz zawierająca ją kompozycja farmaceutyczna |
| UA103104C2 (ru) * | 2009-07-22 | 2013-09-10 | Ипсен Фарма С.А.С. | Аналоги инсулиноподобного фактора роста-1 (igf-1), содержащие аминокислотную замену в положении 59 |
| MX2012002901A (es) | 2009-09-10 | 2012-06-27 | Lonza Biologics Plc | Metodo y sistema para purificacion de polipeptidos. |
| US20110152188A1 (en) * | 2009-12-23 | 2011-06-23 | Hanns-Christian Mahler | Pharmaceutical compositions of igf/i proteins |
| PT2591006T (pt) | 2010-07-09 | 2019-07-29 | Bioverativ Therapeutics Inc | Moléculas de cadeia simples processáveis e polipéptidos preparados utilizando as mesmas |
| WO2013012733A1 (en) | 2011-07-15 | 2013-01-24 | Biogen Idec Ma Inc. | Heterodimeric fc regions, binding molecules comprising same, and methods relating thereto |
| CN104159922B (zh) | 2012-01-10 | 2018-03-02 | 比奥根Ma公司 | 对转运治疗性分子穿过血脑屏障的增强 |
| SG11201503782PA (en) | 2012-12-18 | 2015-06-29 | Novartis Ag | Stabilized insulin-like growth factor polypeptides |
| SG11201505926VA (en) | 2013-03-15 | 2015-09-29 | Biogen Ma Inc | Factor ix polypeptide formulations |
| CN104293766A (zh) * | 2013-07-15 | 2015-01-21 | 四川农业大学 | 山羊IGFBP3基因cDNA编码序列克隆的方法 |
| JP2016535080A (ja) | 2013-10-02 | 2016-11-10 | ノバルティス アーゲー | 療法における使用のためのインスリン様成長因子模倣物 |
| UY35874A (es) | 2013-12-12 | 2015-07-31 | Novartis Ag | Un proceso para la preparación de una composición de proteínas pegiladas |
| MY186251A (en) | 2014-01-20 | 2021-06-30 | Hanmi Pharm Ind Co Ltd | Long-acting insulin and use thereof |
| EP3100056A2 (en) | 2014-01-27 | 2016-12-07 | Novartis AG | Biomarkers predictive of muscle atrophy, method and use |
| AR100639A1 (es) | 2014-05-29 | 2016-10-19 | Hanmi Pharm Ind Co Ltd | Composición para tratar diabetes que comprende conjugados de análogos de insulina de acción prolongada y conjugados de péptidos insulinotrópicos de acción prolongada |
| TWI684458B (zh) | 2014-05-30 | 2020-02-11 | 南韓商韓美藥品股份有限公司 | 包含胰島素及ｇｌｐ-１/昇糖素雙重促效劑之治療糖尿病之組成物 |
| ES2893114T3 (es) | 2015-02-04 | 2022-02-08 | Bristol Myers Squibb Co | Métodos para seleccionar moléculas terapéuticas |
| CA2975525A1 (en) | 2015-02-04 | 2016-08-11 | F. Hoffmann-La Roche Ag | Tau antisense oligomers and uses thereof |
| UY36870A (es) | 2015-08-28 | 2017-03-31 | Hanmi Pharm Ind Co Ltd | Análogos de insulina novedosos |
| AU2017332408B2 (en) | 2016-09-23 | 2022-02-10 | Hanmi Pharm. Co., Ltd. | Insulin analogs with reduced affinity to insulin receptor and use thereof |
| WO2018174668A2 (ko) | 2017-03-23 | 2018-09-27 | 한미약품 주식회사 | 인슐린 수용체와의 결합력이 감소된 인슐린 아날로그의 결합체 및 이의 용도 |
| CN117384275B (zh) * | 2023-12-13 | 2024-03-15 | 北京科为博生物科技有限公司 | 胰岛素样生长因子突变体igf1m及其应用 |
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-
2000
- 2000-01-05 AU AU22245/00A patent/AU762351B2/en not_active Expired
- 2000-01-05 DK DK00901397T patent/DK1141014T3/da active
- 2000-01-05 WO PCT/US2000/000199 patent/WO2000040613A1/en not_active Ceased
- 2000-01-05 AT AT00901397T patent/ATE284415T1/de active
- 2000-01-05 ES ES00901397T patent/ES2234560T3/es not_active Expired - Lifetime
- 2000-01-05 IL IL14386600A patent/IL143866A0/xx unknown
- 2000-01-05 DE DE60016560T patent/DE60016560T2/de not_active Expired - Lifetime
- 2000-01-05 US US09/477,924 patent/US6403764B1/en not_active Expired - Lifetime
- 2000-01-05 CA CA002356109A patent/CA2356109C/en not_active Expired - Lifetime
- 2000-01-05 JP JP2000592321A patent/JP3971108B2/ja not_active Expired - Lifetime
- 2000-01-05 PT PT00901397T patent/PT1141014E/pt unknown
- 2000-01-05 EP EP00901397A patent/EP1141014B1/en not_active Expired - Lifetime
-
2001
- 2001-06-20 IL IL143866A patent/IL143866A/en not_active IP Right Cessation
- 2001-12-19 US US10/028,410 patent/US7105167B2/en not_active Expired - Lifetime
-
2006
- 2006-06-21 JP JP2006171517A patent/JP2006328074A/ja active Pending
- 2006-08-28 US US11/512,046 patent/US8097587B2/en not_active Expired - Fee Related
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