|
DK135130B
(da)
|
1970-12-28 |
1977-03-07 |
Takeda Chemical Industries Ltd |
Analogifremgangsmåde til fremstilling af 2-substituerede adenosinderivater eller syreadditionssalte deraf.
|
|
BE787064A
(fr)
|
1971-08-03 |
1973-02-01 |
Philips Nv |
Dispositif magnetique comportant des domaines
|
|
US3845770A
(en)
*
|
1972-06-05 |
1974-11-05 |
Alza Corp |
Osmatic dispensing device for releasing beneficial agent
|
|
US4089959A
(en)
|
1976-03-31 |
1978-05-16 |
Cooper Laboratories, Inc. |
Long-acting xanthine bronchodilators and antiallergy agents
|
|
US4120947A
(en)
|
1976-03-31 |
1978-10-17 |
Cooper Laboratories, Inc. |
Xanthine compounds and method of treating bronchospastic and allergic diseases
|
|
SE7810946L
(sv)
|
1978-10-20 |
1980-04-21 |
Draco Ab |
Metod att behandla kronisk obstruktiv luftvegssjukdom
|
|
US4326525A
(en)
*
|
1980-10-14 |
1982-04-27 |
Alza Corporation |
Osmotic device that improves delivery properties of agent in situ
|
|
US4593095A
(en)
|
1983-02-18 |
1986-06-03 |
The Johns Hopkins University |
Xanthine derivatives
|
|
US5364620A
(en)
*
|
1983-12-22 |
1994-11-15 |
Elan Corporation, Plc |
Controlled absorption diltiazem formulation for once daily administration
|
|
US4696932A
(en)
|
1984-10-26 |
1987-09-29 |
The United States Of America As Represented By The Department Of Health And Human Services |
Biologically-active xanthine derivatives
|
|
JPS6299395A
(ja)
*
|
1985-10-25 |
1987-05-08 |
Yamasa Shoyu Co Ltd |
２−アルキニルアデノシンおよび抗高血圧剤
|
|
US4968697A
(en)
*
|
1987-02-04 |
1990-11-06 |
Ciba-Geigy Corporation |
2-substituted adenosine 5'-carboxamides as antihypertensive agents
|
|
US5001139A
(en)
*
|
1987-06-12 |
1991-03-19 |
American Cyanamid Company |
Enchancers for the transdermal flux of nivadipine
|
|
US4992445A
(en)
*
|
1987-06-12 |
1991-02-12 |
American Cyanamid Co. |
Transdermal delivery of pharmaceuticals
|
|
US4902514A
(en)
*
|
1988-07-21 |
1990-02-20 |
Alza Corporation |
Dosage form for administering nilvadipine for treating cardiovascular symptoms
|
|
US5070877A
(en)
*
|
1988-08-11 |
1991-12-10 |
Medco Research, Inc. |
Novel method of myocardial imaging
|
|
WO1990005526A1
(fr)
*
|
1988-11-15 |
1990-05-31 |
Yamasa Shoyu Kabushiki Kaisha |
Agent de traitement et de prophylaxie des troubles ischemiques du c×ur ou du cerveau
|
|
IT1229195B
(it)
|
1989-03-10 |
1991-07-25 |
Poli Ind Chimica Spa |
Derivati xantinici ad attivita' broncodilatatrice e loro applicazioni terapeutiche.
|
|
WO1990015812A1
(en)
*
|
1989-06-20 |
1990-12-27 |
Yamasa Shoyu Kabushiki Kaisha |
Intermediate for 2-alkynyladenosine synthesis, production of said intermediate, production of 2-alkynyladenosine from said intermediate, and stable 2-alkynyladenosine derivative
|
|
US5032252A
(en)
*
|
1990-04-27 |
1991-07-16 |
Mobil Oil Corporation |
Process and apparatus for hot catalyst stripping in a bubbling bed catalyst regenerator
|
|
DE4019892A1
(de)
|
1990-06-22 |
1992-01-02 |
Boehringer Ingelheim Kg |
Neue xanthinderivate
|
|
US5189027A
(en)
*
|
1990-11-30 |
1993-02-23 |
Yamasa Shoyu Kabushiki Kaisha |
2-substituted adenosine derivatives and pharmaceutical compositions for circulatory diseases
|
|
FR2671356B1
(fr)
|
1991-01-09 |
1993-04-30 |
Inst Nat Sante Rech Med |
Procede de description des repertoires d'anticorps (ab) et des recepteurs des cellules t (tcr) du systeme immunitaire d'un individu.
|
|
JP2740362B2
(ja)
*
|
1991-02-12 |
1998-04-15 |
ヤマサ醤油株式会社 |
安定な固体状２‐オクチニルアデノシンおよびその製造法
|
|
JP3053908B2
(ja)
|
1991-06-28 |
2000-06-19 |
ヤマサ醤油株式会社 |
２‐アルキニルアデノシン誘導体
|
|
US5516894A
(en)
|
1992-03-11 |
1996-05-14 |
The General Hospital Corporation |
A2b -adenosine receptors
|
|
IT1254915B
(it)
*
|
1992-04-24 |
1995-10-11 |
Gloria Cristalli |
Derivati di adenosina ad attivita' a2 agonista
|
|
GB9210839D0
(en)
|
1992-05-21 |
1992-07-08 |
Smithkline Beecham Plc |
Novel compounds
|
|
WO1993025677A1
(en)
|
1992-06-12 |
1993-12-23 |
Garvan Institute Of Medical Research |
DNA SEQUENCES ENCODING THE HUMAN A1, A2a and A2b ADENOSINE RECEPTORS
|
|
US5705491A
(en)
*
|
1992-10-27 |
1998-01-06 |
Nippon Zoki Pharmaceutical Co., Ltd. |
Adenosine deaminase inhibitor
|
|
CA2112031A1
(en)
|
1992-12-24 |
1994-06-25 |
Fumio Suzuki |
Xanthine derivatives
|
|
WO1995011681A1
(en)
|
1993-10-29 |
1995-05-04 |
Merck & Co., Inc. |
Human adenosine receptor antagonists
|
|
ATE218139T1
(de)
|
1994-02-23 |
2002-06-15 |
Kyowa Hakko Kogyo Kk |
Xanthin-derivate
|
|
US5704491A
(en)
|
1995-07-21 |
1998-01-06 |
Cummins-Allison Corp. |
Method and apparatus for discriminating and counting documents
|
|
US5646156A
(en)
|
1994-04-25 |
1997-07-08 |
Merck & Co., Inc. |
Inhibition of eosinophil activation through A3 adenosine receptor antagonism
|
|
US5877180A
(en)
*
|
1994-07-11 |
1999-03-02 |
University Of Virginia Patent Foundation |
Method for treating inflammatory diseases with A2a adenosine receptor agonists
|
|
US6514949B1
(en)
*
|
1994-07-11 |
2003-02-04 |
University Of Virginia Patent Foundation |
Method compositions for treating the inflammatory response
|
|
US6448235B1
(en)
*
|
1994-07-11 |
2002-09-10 |
University Of Virginia Patent Foundation |
Method for treating restenosis with A2A adenosine receptor agonists
|
|
US5854081A
(en)
|
1996-06-20 |
1998-12-29 |
The University Of Patent Foundation |
Stable expression of human A2B adenosine receptors, and assays employing the same
|
|
US5780481A
(en)
|
1996-08-08 |
1998-07-14 |
Merck & Co., Inc. |
Method for inhibiting activation of the human A3 adenosine receptor to treat asthma
|
|
US5776960A
(en)
|
1996-10-16 |
1998-07-07 |
Buckman Laboratories International, Inc. |
Synergistic antimicrobial compositions containing an ionene polymer and a pyrithione salt and methods of using the same
|
|
US5770716A
(en)
*
|
1997-04-10 |
1998-06-23 |
The Perkin-Elmer Corporation |
Substituted propargylethoxyamido nucleosides, oligonucleotides and methods for using same
|
|
WO1998052611A1
(en)
|
1997-05-23 |
1998-11-26 |
Nippon Shinyaku Co., Ltd. |
Medicinal composition for prevention or treatment of hepatopathy
|
|
WO1998057651A1
(en)
|
1997-06-18 |
1998-12-23 |
Discovery Therapeutics, Inc. |
Compositions and methods for preventing restenosis following revascularization procedures
|
|
US6026317A
(en)
*
|
1998-02-06 |
2000-02-15 |
Baylor College Of Medicine |
Myocardial perfusion imaging during coronary vasodilation with selective adenosine A2 receptor agonists
|
|
US6117878A
(en)
|
1998-02-24 |
2000-09-12 |
University Of Virginia |
8-phenyl- or 8-cycloalkyl xanthine antagonists of A2B human adenosine receptors
|
|
AU4675699A
(en)
|
1998-06-08 |
1999-12-30 |
Epigenesis Pharmaceuticals, Inc. |
Composition and method for prevention and treatment of cardiopulmonary and renal failure or damage associated with ischemia, endotoxin release, ards or brought about by administration of certain drugs
|
|
US6322771B1
(en)
*
|
1999-06-18 |
2001-11-27 |
University Of Virginia Patent Foundation |
Induction of pharmacological stress with adenosine receptor agonists
|
|
US6214807B1
(en)
*
|
1999-06-22 |
2001-04-10 |
Cv Therapeutics, Inc. |
C-pyrazole 2A A receptor agonists
|
|
US6403567B1
(en)
*
|
1999-06-22 |
2002-06-11 |
Cv Therapeutics, Inc. |
N-pyrazole A2A adenosine receptor agonists
|
|
US6368573B1
(en)
*
|
1999-11-15 |
2002-04-09 |
King Pharmaceuticals Research And Development, Inc. |
Diagnostic uses of 2-substituted adenosine carboxamides
|
|
US6605597B1
(en)
*
|
1999-12-03 |
2003-08-12 |
Cv Therapeutics, Inc. |
Partial or full A1agonists-N-6 heterocyclic 5′-thio substituted adenosine derivatives
|
|
US6294522B1
(en)
*
|
1999-12-03 |
2001-09-25 |
Cv Therapeutics, Inc. |
N6 heterocyclic 8-modified adenosine derivatives
|
|
US6677336B2
(en)
*
|
2000-02-22 |
2004-01-13 |
Cv Therapeutics, Inc. |
Substituted piperazine compounds
|
|
US6552023B2
(en)
*
|
2000-02-22 |
2003-04-22 |
Cv Therapeutics, Inc. |
Aralkyl substituted piperazine compounds
|
|
US20020012946A1
(en)
*
|
2000-02-23 |
2002-01-31 |
Luiz Belardinelli |
Method of identifying partial agonists of the A2A receptor
|
|
US6387913B1
(en)
|
2000-12-07 |
2002-05-14 |
S. Jamal Mustafa |
Method of treating airway diseases with combined administration of A2B and A3 adenosine receptor antagonists
|
|
US6670334B2
(en)
*
|
2001-01-05 |
2003-12-30 |
University Of Virginia Patent Foundation |
Method and compositions for treating the inflammatory response
|
|
US6995148B2
(en)
*
|
2001-04-05 |
2006-02-07 |
University Of Pittsburgh |
Adenosine cyclic ketals: novel adenosine analogues for pharmacotherapy
|
|
US6599283B1
(en)
*
|
2001-05-04 |
2003-07-29 |
Cv Therapeutics, Inc. |
Method of preventing reperfusion injury
|
|
WO2002092556A1
(en)
*
|
2001-05-14 |
2002-11-21 |
Novartis Ag |
Sulfonamide derivatives
|
|
ATE520694T1
(de)
|
2001-11-09 |
2011-09-15 |
Gilead Palo Alto Inc |
A2b-adenosinrezeptorantagonisten
|
|
US7125993B2
(en)
|
2001-11-09 |
2006-10-24 |
Cv Therapeutics, Inc. |
A2B adenosine receptor antagonists
|
|
US6977300B2
(en)
|
2001-11-09 |
2005-12-20 |
Cv Therapeutics, Inc. |
A2B adenosine receptor antagonists
|
|
EA007468B1
(ru)
|
2001-12-20 |
2006-10-27 |
Оси Фармасьютикалз, Инк. |
Пиримидиновые соединения, относящиеся к a-селективным антагонистам, их синтез и применение
|
|
AU2003223497A1
(en)
|
2002-04-05 |
2003-10-27 |
Centocor, Inc. |
Asthma-related anti-il-13 immunoglobulin derived proteins, compositions, methods and uses
|
|
KR20050026546A
(ko)
|
2002-07-29 |
2005-03-15 |
씨브이 쎄러퓨틱스, 인코포레이티드 |
Ａ2ａ 수용체 작용제를 이용한 심근 관류 조영
|
|
US20050020915A1
(en)
*
|
2002-07-29 |
2005-01-27 |
Cv Therapeutics, Inc. |
Myocardial perfusion imaging methods and compositions
|
|
ES2426913T3
(es)
|
2004-01-27 |
2013-10-25 |
Gilead Palo Alto, Inc. |
Detección por la imagen de perfusión miocárdica utilizando agonistas del receptor de adenosina
|
|
RU2391103C2
(ru)
|
2004-10-15 |
2010-06-10 |
Си Ви Терапьютикс, Инк. |
Способ предупреждения и лечения ремоделирования дыхательных путей и воспаления легких с применением антагонистов аденозиновых рецепторов a2b
|
|
US7655636B2
(en)
*
|
2004-10-20 |
2010-02-02 |
Gilead Palo Alto, Inc. |
Use of A2A adenosine receptor agonists
|
|
KR20070095925A
(ko)
|
2005-01-12 |
2007-10-01 |
킹 파머슈티칼스 리서치 앤드 디벨로프먼트 아이엔씨 |
천식이나 기관지 경련의 병력이 있는 환자에게서 심근기능장애를 검출하는 방법
|
|
US7732595B2
(en)
|
2006-02-03 |
2010-06-08 |
Gilead Palo Alto, Inc. |
Process for preparing an A2A-adenosine receptor agonist and its polymorphs
|
|
US20070299089A1
(en)
*
|
2006-06-22 |
2007-12-27 |
Cv Therapeutics, Inc. |
Use of A2A Adenosine Receptor Agonists in the Treatment of Ischemia
|
|
US20090081120A1
(en)
|
2006-09-01 |
2009-03-26 |
Cv Therapeutics, Inc. |
Methods and Compositions for Increasing Patient Tolerability During Myocardial Imaging Methods
|
|
BRPI0716174A2
(pt)
*
|
2006-09-01 |
2013-09-24 |
Cv Therapeutics Inc |
mÉtodos e composiÇÕes para aumentar a tolerabilidade de paciente durante mÉtodos de imagem do miocÁrdio.
|
|
JP2011502101A
(ja)
*
|
2006-09-29 |
2011-01-20 |
ギリアード・パロ・アルト・インコーポレイテッド |
肺疾患の病歴を有する患者における心筋画像化法
|
|
US20080267861A1
(en)
*
|
2007-01-03 |
2008-10-30 |
Cv Therapeutics, Inc. |
Myocardial Perfusion Imaging
|
|
RU2011115815A
(ru)
|
2008-09-29 |
2012-11-10 |
Гайлид Сайэнсиз, Инк. (Us) |
Комбинации средства, регулирующего частоту сердечных сокращений и агониста а-2-альфа рецепторов для применения в способах мультидетекторной компьютерной томографии
|