NZ537975A - Method of producing coronary vasodilation without peripheral vasodilation comprising administering at least 10 mcg of at least one A2A receptor agonist - Google Patents
Method of producing coronary vasodilation without peripheral vasodilation comprising administering at least 10 mcg of at least one A2A receptor agonistInfo
- Publication number
- NZ537975A NZ537975A NZ537975A NZ53797503A NZ537975A NZ 537975 A NZ537975 A NZ 537975A NZ 537975 A NZ537975 A NZ 537975A NZ 53797503 A NZ53797503 A NZ 53797503A NZ 537975 A NZ537975 A NZ 537975A
- Authority
- NZ
- New Zealand
- Prior art keywords
- composition
- formula
- compound
- administer
- alkyl
- Prior art date
Links
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
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- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/50—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
- A61B6/507—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for determination of haemodynamic parameters, e.g. perfusion CT
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Animal Behavior & Ethology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| US39917602P | 2002-07-29 | 2002-07-29 | |
| US42690202P | 2002-11-15 | 2002-11-15 | |
| US45980303P | 2003-04-02 | 2003-04-02 | |
| PCT/US2003/023511 WO2004011010A1 (en) | 2002-07-29 | 2003-07-29 | Myocardial perfusion imaging using a2a receptor agonists |
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| NZ537975A NZ537975A (en) | 2002-07-29 | 2003-07-29 | Method of producing coronary vasodilation without peripheral vasodilation comprising administering at least 10 mcg of at least one A2A receptor agonist |
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| WO (1) | WO2004011010A1 (enExample) |
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| US6214807B1 (en) | 1999-06-22 | 2001-04-10 | Cv Therapeutics, Inc. | C-pyrazole 2A A receptor agonists |
| USRE47351E1 (en) | 1999-06-22 | 2019-04-16 | Gilead Sciences, Inc. | 2-(N-pyrazolo)adenosines with application as adenosine A2A receptor agonists |
| US6403567B1 (en) * | 1999-06-22 | 2002-06-11 | Cv Therapeutics, Inc. | N-pyrazole A2A adenosine receptor agonists |
| CA2439222C (en) | 2000-02-23 | 2009-07-14 | Cv Therapeutics, Inc. | Identification of partial agonists of the a2a adenosine receptor |
| US8470801B2 (en) | 2002-07-29 | 2013-06-25 | Gilead Sciences, Inc. | Myocardial perfusion imaging methods and compositions |
| AU2003259264A1 (en) | 2002-07-29 | 2004-02-16 | Cv Therapeutics, Inc. | Myocardial perfusion imaging using a2a receptor agonists |
| US20050020915A1 (en) * | 2002-07-29 | 2005-01-27 | Cv Therapeutics, Inc. | Myocardial perfusion imaging methods and compositions |
| WO2005013801A2 (en) * | 2003-07-18 | 2005-02-17 | Munn Charles S | Enhanced cardiac radionuclide imaging techniques |
| WO2005082379A1 (en) * | 2004-01-27 | 2005-09-09 | Cv Therapeutics, Inc. | Myocardial perfusion imaging using adenosine receptor agonists |
| JP2008517063A (ja) * | 2004-10-20 | 2008-05-22 | シーブイ・セラピューティクス・インコーポレイテッド | Ａ２ａアデノシンレセプターアゴニストの使用 |
| US7381714B2 (en) * | 2005-05-19 | 2008-06-03 | Cv Therapeutics, Inc. | A1 adenosine receptor agonists |
| WO2007092372A1 (en) | 2006-02-03 | 2007-08-16 | Cv Therapeutics, Inc. | Process for preparing an a2a-adenosine receptor agonist and its polymorphs |
| EP2068850A1 (en) * | 2006-06-22 | 2009-06-17 | Cv Therapeutics, Inc. | Use of a2a adenosine receptor agonists in the treatment of ischemia |
| US20090081120A1 (en) * | 2006-09-01 | 2009-03-26 | Cv Therapeutics, Inc. | Methods and Compositions for Increasing Patient Tolerability During Myocardial Imaging Methods |
| CN101511366B (zh) * | 2006-09-01 | 2011-12-28 | 吉利德帕洛阿尔托股份有限公司 | 在心肌显像方法期间用于增加患者耐受性的方法和组合物 |
| CA2663361A1 (en) * | 2006-09-29 | 2008-04-10 | Cv Therapeutics, Inc. | Methods for myocardial imaging in patients having a history of pulmonary disease |
| EP2099360A2 (en) * | 2007-01-03 | 2009-09-16 | CV Therapeutics Inc. | Myocardial perfusion imaging |
| WO2010037122A1 (en) * | 2008-09-29 | 2010-04-01 | Gilead Palo Alto, Inc. | Combinations of a rate control agent and an a-2-alpha receptor antagonist for use in multidetector computed tomography methods |
| US11730430B2 (en) * | 2012-09-21 | 2023-08-22 | The General Hospital Corporation | System and method for single-scan rest-stress cardiac pet |
| EP2908858B1 (en) | 2012-10-19 | 2020-06-24 | New York University | Compositions for use in inhibiting osteolysis |
| WO2014083580A2 (en) * | 2012-11-30 | 2014-06-05 | Leiutis Pharmaceuticals Pvt. Ltd. | Pharmaceutical compositions of regadenoson |
| CN105997852B (zh) * | 2016-05-15 | 2018-10-09 | 南京海融医药科技股份有限公司 | 一种瑞加诺生注射液及其制备方法 |
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| AU2003259264A1 (en) | 2002-07-29 | 2004-02-16 | Cv Therapeutics, Inc. | Myocardial perfusion imaging using a2a receptor agonists |
| WO2005082379A1 (en) | 2004-01-27 | 2005-09-09 | Cv Therapeutics, Inc. | Myocardial perfusion imaging using adenosine receptor agonists |
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| JP2008527003A (ja) | 2005-01-12 | 2008-07-24 | キング・ファーマシューティカルズ・リサーチ・アンド・デベロプメント・インコーポレイティッド | 喘息又は気管支痙攣の既往歴を有する患者における心筋機能不全を検出する方法 |
| WO2007092372A1 (en) | 2006-02-03 | 2007-08-16 | Cv Therapeutics, Inc. | Process for preparing an a2a-adenosine receptor agonist and its polymorphs |
| EP2068850A1 (en) * | 2006-06-22 | 2009-06-17 | Cv Therapeutics, Inc. | Use of a2a adenosine receptor agonists in the treatment of ischemia |
| CN101511366B (zh) * | 2006-09-01 | 2011-12-28 | 吉利德帕洛阿尔托股份有限公司 | 在心肌显像方法期间用于增加患者耐受性的方法和组合物 |
| US20090081120A1 (en) | 2006-09-01 | 2009-03-26 | Cv Therapeutics, Inc. | Methods and Compositions for Increasing Patient Tolerability During Myocardial Imaging Methods |
| CA2663361A1 (en) * | 2006-09-29 | 2008-04-10 | Cv Therapeutics, Inc. | Methods for myocardial imaging in patients having a history of pulmonary disease |
| EP2099360A2 (en) * | 2007-01-03 | 2009-09-16 | CV Therapeutics Inc. | Myocardial perfusion imaging |
| WO2010037122A1 (en) | 2008-09-29 | 2010-04-01 | Gilead Palo Alto, Inc. | Combinations of a rate control agent and an a-2-alpha receptor antagonist for use in multidetector computed tomography methods |
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2003
- 2003-07-29 AU AU2003259264A patent/AU2003259264A1/en not_active Abandoned
- 2003-07-29 NZ NZ537975A patent/NZ537975A/en not_active IP Right Cessation
- 2003-07-29 CA CA2492855A patent/CA2492855C/en not_active Expired - Lifetime
- 2003-07-29 JP JP2005505626A patent/JP2005538190A/ja active Pending
- 2003-07-29 US US10/629,368 patent/US7683037B2/en not_active Expired - Fee Related
- 2003-07-29 CN CNA038175924A patent/CN1671399A/zh active Pending
- 2003-07-29 KR KR1020057001708A patent/KR20050026546A/ko not_active Withdrawn
- 2003-07-29 EP EP03771950A patent/EP1524984A1/en not_active Withdrawn
- 2003-07-29 MX MXPA05001123A patent/MXPA05001123A/es active IP Right Grant
- 2003-07-29 WO PCT/US2003/023511 patent/WO2004011010A1/en not_active Ceased
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2005
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- 2005-02-25 NO NO20051059A patent/NO20051059L/no not_active Application Discontinuation
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2010
- 2010-01-27 US US12/695,096 patent/US8183226B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
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| US8183226B2 (en) | 2012-05-22 |
| WO2004011010A1 (en) | 2004-02-05 |
| US7683037B2 (en) | 2010-03-23 |
| CA2492855A1 (en) | 2004-02-05 |
| JP2005538190A (ja) | 2005-12-15 |
| US20040064039A1 (en) | 2004-04-01 |
| CA2492855C (en) | 2012-09-18 |
| NO20051059L (no) | 2005-02-25 |
| IL166555A0 (en) | 2006-01-15 |
| US20100272645A1 (en) | 2010-10-28 |
| AU2003259264A1 (en) | 2004-02-16 |
| EP1524984A1 (en) | 2005-04-27 |
| MXPA05001123A (es) | 2005-04-29 |
| CN1671399A (zh) | 2005-09-21 |
| KR20050026546A (ko) | 2005-03-15 |
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