JP2005536480A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2005536480A5 JP2005536480A5 JP2004513274A JP2004513274A JP2005536480A5 JP 2005536480 A5 JP2005536480 A5 JP 2005536480A5 JP 2004513274 A JP2004513274 A JP 2004513274A JP 2004513274 A JP2004513274 A JP 2004513274A JP 2005536480 A5 JP2005536480 A5 JP 2005536480A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- compound
- general formula
- alkyl
- atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 17
- 125000000217 alkyl group Chemical group 0.000 claims 12
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 8
- 125000005843 halogen group Chemical group 0.000 claims 7
- 229910052801 chlorine Inorganic materials 0.000 claims 5
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims 4
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 claims 4
- 125000006239 protecting group Chemical group 0.000 claims 4
- 125000003808 silyl group Chemical group [H][Si]([H])([H])[*] 0.000 claims 4
- 125000001412 tetrahydropyranyl group Chemical group 0.000 claims 4
- 125000001309 chloro group Chemical group Cl* 0.000 claims 3
- 229910052731 fluorine Inorganic materials 0.000 claims 3
- 125000001153 fluoro group Chemical group F* 0.000 claims 3
- HBBGRARXTFLTSG-UHFFFAOYSA-N Lithium ion Chemical compound [Li+] HBBGRARXTFLTSG-UHFFFAOYSA-N 0.000 claims 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims 2
- 229910052794 bromium Inorganic materials 0.000 claims 2
- 239000000460 chlorine Substances 0.000 claims 2
- 229910001416 lithium ion Inorganic materials 0.000 claims 2
- 229910052749 magnesium Inorganic materials 0.000 claims 2
- 239000011777 magnesium Substances 0.000 claims 2
- 229910052751 metal Inorganic materials 0.000 claims 2
- 239000002184 metal Substances 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000012038 nucleophile Substances 0.000 claims 2
- 150000007944 thiolates Chemical class 0.000 claims 2
- -1 CF 3 Chemical group 0.000 claims 1
- 150000001350 alkyl halides Chemical class 0.000 claims 1
- 230000007062 hydrolysis Effects 0.000 claims 1
- 238000006460 hydrolysis reaction Methods 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 claims 1
- 0 Cc1c(CSc2ccc(*)cc2)[s]c(-c2ccccc2)n1 Chemical compound Cc1c(CSc2ccc(*)cc2)[s]c(-c2ccccc2)n1 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2002-0024595A KR100474202B1 (ko) | 2002-05-04 | 2002-05-04 | 티아졸 유도체의 제조방법 및 이를 제조하기 위한 중간체 |
| PCT/KR2003/000877 WO2003106442A1 (en) | 2002-05-04 | 2003-05-01 | Process for preparing thiazole derivative and the intermediate compounds for preparing the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005536480A JP2005536480A (ja) | 2005-12-02 |
| JP2005536480A5 true JP2005536480A5 (enExample) | 2006-09-07 |
Family
ID=29728605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004513274A Pending JP2005536480A (ja) | 2002-05-04 | 2003-05-01 | チアゾール誘導体の製造方法及びこれを製造するための中間体 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7241901B2 (enExample) |
| EP (1) | EP1501811B1 (enExample) |
| JP (1) | JP2005536480A (enExample) |
| KR (1) | KR100474202B1 (enExample) |
| CN (1) | CN100457744C (enExample) |
| DE (1) | DE60328376D1 (enExample) |
| ES (1) | ES2330095T3 (enExample) |
| WO (1) | WO2003106442A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2598821C (en) * | 2004-12-31 | 2011-05-31 | Heonjoong Kang | Organoselenium containing compounds and their use |
| KR100753860B1 (ko) * | 2004-12-31 | 2007-08-31 | 재단법인서울대학교산학협력재단 | 유기 셀레늄 함유 화합물 및 이들 화합물의 용도 |
| WO2006091047A1 (en) * | 2005-02-25 | 2006-08-31 | Heonjoong Kang | Thiazole derivatives as ppar delta ligands and their manufacturing process |
| BRPI0606232A2 (pt) * | 2005-02-25 | 2009-06-09 | Kang Heonjoong | derivados de tiazole como os ligantes delta ppar e seus processos de produção |
| US7982050B2 (en) | 2005-05-07 | 2011-07-19 | Seoul National University Industry Foundation | Process for preparing ligands of PPARdelta and the intermediate compounds for preparing the same |
| CN101400663A (zh) * | 2006-01-10 | 2009-04-01 | 史密丝克莱恩比彻姆公司 | {2-甲基-4-[4-甲基-2-(4-三氟甲基苯基)噻唑-5-基甲硫基]苯氧基}-乙酸的多晶型 |
| KR101005020B1 (ko) | 2006-12-13 | 2010-12-30 | 대전대학교 산학협력단 | 신규 쿠마린 유도체 및 이를 함유하는 항염증, 항알러지용조성물 |
| KR100954237B1 (ko) | 2007-01-08 | 2010-04-21 | 재단법인서울대학교산학협력재단 | 퍼록시솜 증식자 활성화 수용체 델타 리간드 티아졸 화합물및 이를 함유하는 의약, 화장품 및 건강식품 조성물 |
| CN107879994A (zh) * | 2017-10-31 | 2018-04-06 | 广西师范大学 | 一种噻唑类化合物的合成方法 |
| CN109897013B (zh) * | 2019-03-31 | 2023-04-07 | 无锡科华生物科技有限公司 | 一种选择性PPARδ激动剂GW501516的制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4727187A (en) * | 1984-06-15 | 1988-02-23 | Ciba-Geigy Corporation | Process for the preparation of α, α-difluoroalkyl phenyl ether derivatives |
| JPH06306005A (ja) * | 1993-04-23 | 1994-11-01 | Nippon Kayaku Co Ltd | エーテル系化合物及びその製法 |
| PL331861A1 (en) * | 1996-08-19 | 1999-08-16 | Japan Tobacco Inc | Derivatives of propionic acid and their application |
| DE69941777D1 (de) * | 1998-03-10 | 2010-01-21 | Ono Pharmaceutical Co | Carbonsäurederivate und medikamente die diese als aktiven wirkstoff enthalten |
| GB9817118D0 (en) * | 1998-08-07 | 1998-10-07 | Glaxo Group Ltd | Pharmaceutical compounds |
| GB9914977D0 (en) * | 1999-06-25 | 1999-08-25 | Glaxo Group Ltd | Chemical compounds |
| PE20011010A1 (es) * | 1999-12-02 | 2001-10-18 | Glaxo Group Ltd | Oxazoles y tiazoles sustituidos como agonista del receptor activado por el proliferador de peroxisomas humano |
| JP2001354671A (ja) * | 2000-04-14 | 2001-12-25 | Nippon Chemiphar Co Ltd | ペルオキシソーム増殖剤応答性受容体δの活性化剤 |
| ATE542805T1 (de) * | 2000-08-11 | 2012-02-15 | Nippon Chemiphar Co | Ppar-delta aktivatoren |
| US7091225B2 (en) | 2000-12-20 | 2006-08-15 | Smithkline Beecham Corporation | Substituted oxazoles and thiazoles as hPPAR alpha agonists |
| WO2002070011A2 (en) * | 2001-02-02 | 2002-09-12 | Smithkline Beecham Corporation | Treatment of ppar mediated diseases |
| AU2003213281A1 (en) * | 2002-02-28 | 2003-09-16 | Smithkline Beecham Corporation | Process and intermediates for preparing phenylthiomethyl-thiazoles or oxazoles |
-
2002
- 2002-05-04 KR KR10-2002-0024595A patent/KR100474202B1/ko not_active Expired - Fee Related
-
2003
- 2003-05-01 EP EP03721130A patent/EP1501811B1/en not_active Expired - Lifetime
- 2003-05-01 CN CNB038100819A patent/CN100457744C/zh not_active Expired - Fee Related
- 2003-05-01 DE DE60328376T patent/DE60328376D1/de not_active Expired - Lifetime
- 2003-05-01 JP JP2004513274A patent/JP2005536480A/ja active Pending
- 2003-05-01 WO PCT/KR2003/000877 patent/WO2003106442A1/en not_active Ceased
- 2003-05-01 US US10/513,408 patent/US7241901B2/en not_active Expired - Lifetime
- 2003-05-01 ES ES03721130T patent/ES2330095T3/es not_active Expired - Lifetime
-
2007
- 2007-04-03 US US11/730,658 patent/US20070179300A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2005536480A5 (enExample) | ||
| JP2003529564A5 (enExample) | ||
| US20090177003A1 (en) | Process for obtaining halogenated monoorganoxysilanes which can be used in particular as sysnthesis intermediates | |
| US6984747B2 (en) | Method for preparing styryl-functionalized silanes | |
| JP2007523970A5 (enExample) | ||
| JP2005523935A5 (enExample) | ||
| EP1403272A8 (en) | Process for preparation of phosphoric esters | |
| JPH07173179A (ja) | 含フッ素有機ケイ素化合物 | |
| CN106883266A (zh) | 一种1‑（4‑氯苯基）‑2‑环丙基‑1‑丙酮的制备方法及其中间体 | |
| JP2003012683A5 (enExample) | ||
| JP2005536480A (ja) | チアゾール誘導体の製造方法及びこれを製造するための中間体 | |
| JP2005526612A5 (enExample) | ||
| JP4054957B2 (ja) | テトラキス（ジメチルアミノ）シランの塩素分低減方法 | |
| JP2002167391A (ja) | 有機シランの製造方法 | |
| JP2011513358A5 (enExample) | ||
| KR100668045B1 (ko) | ω-[2-(폴리알킬렌옥시)에틸티오]알킬알콕시실레인유도체와 이의 제조방법 | |
| JP2007001918A5 (ja) | シリコーンモノマーの製造方法、シリコーンモノマーおよび眼用レンズ | |
| JP2004002247A5 (enExample) | ||
| RU2007104036A (ru) | Способ получения диизопропил (гидроксиметил)-циклопропил)окси) метилфосфоната | |
| JP7168766B2 (ja) | ジクロロシランを脱水素化する方法 | |
| EP1120402A3 (en) | Chiral copper complex and production processes thereof and using the same | |
| JP2011256120A (ja) | オルガノアミノシラン化合物の製造方法 | |
| JP2006509087A5 (enExample) | ||
| US4677216A (en) | 2-Substituted-1,3-butadiene derivatives and process for producing same | |
| JPH10316686A (ja) | トリチルテトラキス（ペンタフルオロフェニル）ボレートの製造方法 |