JP2005533832A - 酸不安定性薬物の液体剤形 - Google Patents

酸不安定性薬物の液体剤形 Download PDF

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Publication number
JP2005533832A
JP2005533832A JP2004519788A JP2004519788A JP2005533832A JP 2005533832 A JP2005533832 A JP 2005533832A JP 2004519788 A JP2004519788 A JP 2004519788A JP 2004519788 A JP2004519788 A JP 2004519788A JP 2005533832 A JP2005533832 A JP 2005533832A
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JP
Japan
Prior art keywords
acid labile
composition
microparticles
liquid
less
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004519788A
Other languages
English (en)
Japanese (ja)
Inventor
タネジヤ，ラジネーシユ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of JP2005533832A publication Critical patent/JP2005533832A/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2004519788A 2002-07-03 2003-07-02 酸不安定性薬物の液体剤形 Pending JP2005533832A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/190,242 US20040005362A1 (en) 2002-07-03 2002-07-03 Liquid dosage forms of acid labile drugs
PCT/US2003/020875 WO2004004718A1 (en) 2002-07-03 2003-07-02 Liquid dosage forms of acid labile drugs

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011179648A Division JP2012021008A (ja) 2002-07-03 2011-08-19 酸不安定性薬物の液体剤形

Publications (1)

Publication Number Publication Date
JP2005533832A true JP2005533832A (ja) 2005-11-10

Family

ID=29999830

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2004519788A Pending JP2005533832A (ja) 2002-07-03 2003-07-02 酸不安定性薬物の液体剤形
JP2011179648A Withdrawn JP2012021008A (ja) 2002-07-03 2011-08-19 酸不安定性薬物の液体剤形
JP2015021882A Expired - Fee Related JP5997788B2 (ja) 2002-07-03 2015-02-06 酸不安定性薬物の液体剤形
JP2016049674A Expired - Fee Related JP6209237B2 (ja) 2002-07-03 2016-03-14 酸不安定性薬物の液体剤形
JP2017115697A Pending JP2017206525A (ja) 2002-07-03 2017-06-13 酸不安定性薬物の液体剤形

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2011179648A Withdrawn JP2012021008A (ja) 2002-07-03 2011-08-19 酸不安定性薬物の液体剤形
JP2015021882A Expired - Fee Related JP5997788B2 (ja) 2002-07-03 2015-02-06 酸不安定性薬物の液体剤形
JP2016049674A Expired - Fee Related JP6209237B2 (ja) 2002-07-03 2016-03-14 酸不安定性薬物の液体剤形
JP2017115697A Pending JP2017206525A (ja) 2002-07-03 2017-06-13 酸不安定性薬物の液体剤形

Country Status (7)

Country Link
US (1) US20040005362A1 (enExample)
EP (1) EP1539156B8 (enExample)
JP (5) JP2005533832A (enExample)
CA (1) CA2490145C (enExample)
ES (1) ES2401102T3 (enExample)
MX (1) MXPA05000298A (enExample)
WO (1) WO2004004718A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015172032A (ja) * 2014-02-20 2015-10-01 ライオン株式会社 経口製剤及びその製造方法

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040082618A1 (en) * 2002-07-03 2004-04-29 Rajneesh Taneja Liquid dosage forms of acid labile drugs
US20050220870A1 (en) * 2003-02-20 2005-10-06 Bonnie Hepburn Novel formulation, omeprazole antacid complex-immediate release for rapid and sustained suppression of gastric acid
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
TWI398273B (zh) * 2003-07-18 2013-06-11 Santarus Inc 用於抑制酸分泌之醫藥調配物及其製備及使用之方法
MXPA06000524A (es) * 2003-07-18 2006-08-11 Santarus Inc Formulacion farmaceutica y metodo para tratar desordenes gastrointestinales provocados por acido.
TWI372066B (en) 2003-10-01 2012-09-11 Wyeth Corp Pantoprazole multiparticulate formulations
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
EP1718303A4 (en) * 2004-02-10 2010-09-01 Santarus Inc COMBINATION OF INHIBITOR OF PROTON PUMP, BUFFER AND NON-STEROIDAL ANTI-INFLAMMATORY DRUG
AU2005249367A1 (en) * 2004-04-16 2005-12-15 Santarus, Inc. Combination of proton pump inhibitor, buffering agent, and prokinetic agent
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20060134210A1 (en) * 2004-12-22 2006-06-22 Astrazeneca Ab Solid dosage form comprising proton pump inhibitor and suspension made thereof
US20090092658A1 (en) * 2007-10-05 2009-04-09 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations
WO2015089178A1 (en) * 2013-12-12 2015-06-18 Hollister Incorporated Flushable disintegration catheter
EP3117824A1 (en) * 2015-07-17 2017-01-18 BE Pharbel Manufacturing Multilayered pharmaceutically active compound-releasing microparticles in a liquid dosage form
BE1024339B1 (fr) * 2016-07-01 2018-01-29 Be Pharbel Mfg Sa Microparticules multicouches libérant un composé pharmaceutiquement actif dans une forme pharmaceutique liquide
JP6796132B2 (ja) * 2015-07-17 2020-12-02 ビーイー ファーベル マニュファクチャリング 液体剤形中の薬学的活性化合物放出性多層微小粒子
US12472149B2 (en) 2015-07-17 2025-11-18 BE Pharbel Manufacturing Multilayered pharmaceutically active compound-releasing microparticles in a liquid dosage form

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06502194A (ja) * 1991-07-22 1994-03-10 ラボラトワール　プログラファルム 急速崩壊性多粒子状錠剤
JPH08509493A (ja) * 1993-04-30 1996-10-08 アストラ・アクチエボラーグ プロトンポンプ阻害剤含有獣医薬組成物
JPH11501951A (ja) * 1996-01-08 1999-02-16 アストラ・アクチエボラーグ プロトンポンプ抑制剤を含有するマルチプルユニットの沸騰剤形
JPH1143429A (ja) * 1997-05-27 1999-02-16 Takeda Chem Ind Ltd 固形製剤
JP2000281564A (ja) * 1998-05-18 2000-10-10 Takeda Chem Ind Ltd 医薬製剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2189698A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
US4808411A (en) * 1987-06-05 1989-02-28 Abbott Laboratories Antibiotic-polymer compositions
US5464632C1 (en) * 1991-07-22 2001-02-20 Prographarm Lab Rapidly disintegratable multiparticular tablet
JPH06319496A (ja) * 1993-05-11 1994-11-22 Seiichi Kudo リンゴジュース
US5824339A (en) * 1995-09-08 1998-10-20 Takeda Chemical Industries, Ltd Effervescent composition and its production
TW580397B (en) * 1997-05-27 2004-03-21 Takeda Chemical Industries Ltd Solid preparation
MXPA00007428A (es) * 1998-01-30 2002-08-20 Flow Int Corp Metodo para la inactivacion a presion ultra alta de microrganismos en productos de jugo.
YU86001A (sh) * 1999-06-07 2004-07-15 Altana Pharma Ag. Novi preparat i oblik, u kojem se daje lek, koji sadrži aktivno jedinjenje labilno prema kiselini
AU2002234545A1 (en) * 2000-12-07 2002-06-18 Byk Gulden Lomberg Chemische Fabrik G.M.B.H. Pharmaceutical preparation in the form of a suspension comprising an acid-labileactive ingredient

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06502194A (ja) * 1991-07-22 1994-03-10 ラボラトワール　プログラファルム 急速崩壊性多粒子状錠剤
JPH08509493A (ja) * 1993-04-30 1996-10-08 アストラ・アクチエボラーグ プロトンポンプ阻害剤含有獣医薬組成物
JPH11501951A (ja) * 1996-01-08 1999-02-16 アストラ・アクチエボラーグ プロトンポンプ抑制剤を含有するマルチプルユニットの沸騰剤形
JPH1143429A (ja) * 1997-05-27 1999-02-16 Takeda Chem Ind Ltd 固形製剤
JP2000281564A (ja) * 1998-05-18 2000-10-10 Takeda Chem Ind Ltd 医薬製剤

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015172032A (ja) * 2014-02-20 2015-10-01 ライオン株式会社 経口製剤及びその製造方法

Also Published As

Publication number Publication date
EP1539156B1 (en) 2012-12-12
CA2490145A1 (en) 2004-01-15
WO2004004718A1 (en) 2004-01-15
EP1539156A1 (en) 2005-06-15
US20040005362A1 (en) 2004-01-08
MXPA05000298A (es) 2005-03-31
JP2016164165A (ja) 2016-09-08
JP2012021008A (ja) 2012-02-02
JP6209237B2 (ja) 2017-10-04
JP5997788B2 (ja) 2016-09-28
JP2015134776A (ja) 2015-07-27
ES2401102T3 (es) 2013-04-17
CA2490145C (en) 2016-05-31
EP1539156B8 (en) 2013-02-06
JP2017206525A (ja) 2017-11-24

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