JP2005533001A5 - - Google Patents
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- Publication number
- JP2005533001A5 JP2005533001A5 JP2003574230A JP2003574230A JP2005533001A5 JP 2005533001 A5 JP2005533001 A5 JP 2005533001A5 JP 2003574230 A JP2003574230 A JP 2003574230A JP 2003574230 A JP2003574230 A JP 2003574230A JP 2005533001 A5 JP2005533001 A5 JP 2005533001A5
- Authority
- JP
- Japan
- Prior art keywords
- vitaxin
- fragment
- binding
- integrin
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36185902P | 2002-03-04 | 2002-03-04 | |
| US37039802P | 2002-04-05 | 2002-04-05 | |
| US44426503P | 2003-01-30 | 2003-01-30 | |
| PCT/US2003/006684 WO2003075957A1 (en) | 2002-03-04 | 2003-03-04 | The prevention or treatment of cancer using integrin alphavbeta3 antagonists in combination with other agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005533001A JP2005533001A (ja) | 2005-11-04 |
| JP2005533001A5 true JP2005533001A5 (enExample) | 2006-01-12 |
Family
ID=27808630
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003574230A Pending JP2005533001A (ja) | 2002-03-04 | 2003-03-04 | インテグリンαvβ3アンタゴニストを他の物質と併用投与する癌の予防または治療方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20040001835A1 (enExample) |
| EP (1) | EP1487492A4 (enExample) |
| JP (1) | JP2005533001A (enExample) |
| AU (2) | AU2003217930A1 (enExample) |
| CA (1) | CA2478239A1 (enExample) |
| WO (1) | WO2003075957A1 (enExample) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1613273B1 (en) | 2003-04-11 | 2012-06-13 | MedImmune, LLC | Recombinant il-9 antibodies and uses thereof |
| ES2342461T3 (es) * | 2003-10-17 | 2010-07-07 | Oy Neurofood Ab | Agente de estroncio no radiactivo para tratar el cancer. |
| US7271245B2 (en) * | 2004-02-13 | 2007-09-18 | The Scripps Research Institute | Methods and compositions for inhibition of metastasis |
| US20100009928A1 (en) | 2004-03-29 | 2010-01-14 | Cheng Jin Q | Compositions including triciribine and taxanes and methods of use thereof |
| EP2574341B1 (en) | 2004-03-29 | 2017-03-29 | University Of South Florida | Effective treatment of tumors and cancer with triciribine phosphate |
| US20100173864A1 (en) | 2004-03-29 | 2010-07-08 | Cheng Jin Q | Compositions including triciribine and one or more platinum compounds and methods of use thereof |
| US20100009929A1 (en) | 2004-03-29 | 2010-01-14 | Cheng Jin Q | Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof |
| US20110008327A1 (en) | 2004-03-29 | 2011-01-13 | Cheng Jin Q | Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof |
| US20100028339A1 (en) | 2004-03-29 | 2010-02-04 | Cheng Jin Q | Compositions including triciribine and trastuzumab and methods of use thereof |
| US7691379B2 (en) | 2004-04-12 | 2010-04-06 | Medimmune, Llc | Anti-IL-9 antibody formulations |
| US7329495B2 (en) | 2004-06-09 | 2008-02-12 | Board Of Regents, The University Of Texas System | Mutations in KIT confer imatinib resistance in gastrointestinal stromal tumors |
| WO2006023420A2 (en) * | 2004-08-16 | 2006-03-02 | Medimmune, Inc. | Integrin antagonists with enhanced antibody dependent cell-mediated cytotoxicity activity |
| AU2006261920A1 (en) | 2005-06-23 | 2007-01-04 | Medimmune, Llc | Antibody formulations having optimized aggregation and fragmentation profiles |
| CN1870631B (zh) * | 2005-11-11 | 2010-04-14 | 华为技术有限公司 | 媒体网关的门控方法 |
| US20110165150A1 (en) * | 2006-01-18 | 2011-07-07 | Merck Patent Gmbh | Isolated organ perfusion combination therapy of cancer |
| EP1973569B1 (en) * | 2006-01-18 | 2013-05-22 | Merck Patent GmbH | Specific therapy using integrin ligands for treating cancer |
| WO2009018386A1 (en) | 2007-07-31 | 2009-02-05 | Medimmune, Llc | Multispecific epitope binding proteins and uses thereof |
| BRPI0907046A2 (pt) | 2008-01-18 | 2015-07-28 | Medimmune Llc | Anticorpo de cisteína engenheirada, ácido nucleico isolado, vetor, célula hospedeira, conjugado de anticorpo, composição farmacêutica, métodos de detecção de câncer, doenças ou distúrbios autoimunes, inflamatórios ou infecciosos em um indivíduo e de inibição de proliferação de uma célula alvo |
| AU2009233322B2 (en) | 2008-03-31 | 2014-04-17 | Council Of Scientific & Industrial Research | A tumor model system useful to study multistage cancer |
| US8775090B2 (en) | 2008-12-12 | 2014-07-08 | Medimmune, Llc | Crystals and structure of a human IgG Fc variant with enhanced FcRn binding |
| AU2010285265B2 (en) | 2009-08-19 | 2015-05-21 | Merck Patent Gmbh | Antibodies for the detection of integrin complexes in FFPE material |
| KR20130056855A (ko) | 2010-03-01 | 2013-05-30 | 카리스 라이프 사이언스 룩셈부르크 홀딩스 | 치료진단용 생물학적 지표들 |
| KR20130043104A (ko) | 2010-04-06 | 2013-04-29 | 카리스 라이프 사이언스 룩셈부르크 홀딩스 | 질병용 순환 생물학적 지표들 |
| WO2012019061A2 (en) | 2010-08-05 | 2012-02-09 | Stem Centrx, Inc. | Novel effectors and methods of use |
| CA2809369A1 (en) | 2010-08-27 | 2012-03-01 | Stem Centrx, Inc. | Notum protein modulators and methods of use |
| BR112013005116A2 (pt) | 2010-09-03 | 2019-09-24 | Stem Centrx Inc | moduladores e métodos de uso |
| AU2011325833C1 (en) | 2010-11-05 | 2017-07-13 | Zymeworks Bc Inc. | Stable heterodimeric antibody design with mutations in the Fc domain |
| MX356400B (es) | 2010-12-08 | 2018-05-28 | Abbvie Stemcentrx Llc | Moduladores novedosos y metodos de uso. |
| US20120164449A1 (en) * | 2010-12-23 | 2012-06-28 | Stephen Woodrow Foss | Fibers with improving anti-microbial performance |
| SA112330278B1 (ar) | 2011-02-18 | 2015-10-09 | ستيم سينتركس، انك. | مواد ضابطة جديدة وطرق للاستخدام |
| US9244074B2 (en) | 2011-06-07 | 2016-01-26 | University Of Hawaii | Biomarker of asbestos exposure and mesothelioma |
| WO2012170742A2 (en) | 2011-06-07 | 2012-12-13 | University Of Hawaii | Treatment and prevention of cancer with hmgb1 antagonists |
| CA2842796A1 (en) * | 2011-07-22 | 2013-01-31 | Pawel Kalinski | Tumor selective chemokine modulation |
| US20130058947A1 (en) | 2011-09-02 | 2013-03-07 | Stem Centrx, Inc | Novel Modulators and Methods of Use |
| CN103534273B (zh) * | 2011-09-16 | 2020-05-12 | 北京沙东生物技术有限公司 | 环化变构trail/apo2l及其编码基因与应用 |
| WO2013067054A1 (en) | 2011-11-01 | 2013-05-10 | Bionomics, Inc. | Antibodies and methods of treating cancer |
| US10598653B2 (en) | 2011-11-01 | 2020-03-24 | Bionomics Inc. | Methods of blocking cancer stem cell growth |
| US9220774B2 (en) | 2011-11-01 | 2015-12-29 | Bionomics Inc. | Methods of treating cancer by administering anti-GPR49 antibodies |
| WO2013067060A1 (en) | 2011-11-01 | 2013-05-10 | Bionomics, Inc. | Anti-gpr49 antibodies |
| AU2012332021B8 (en) | 2011-11-04 | 2017-10-12 | Zymeworks Bc Inc. | Stable heterodimeric antibody design with mutations in the Fc domain |
| KR102099073B1 (ko) | 2012-02-24 | 2020-04-10 | 애브비 스템센트알엑스 엘엘씨 | 항 sez6 항체들 및 사용 방법 |
| EP3093294A1 (en) | 2012-02-24 | 2016-11-16 | Stemcentrx, Inc. | Dll3 modulators and methods of use |
| WO2013166594A1 (en) | 2012-05-10 | 2013-11-14 | Zymeworks Inc. | Heteromultimer constructs of immunoglobulin heavy chains with mutations in the fc domain |
| CA2820547A1 (en) | 2012-07-02 | 2014-01-02 | University Of South Florida (A Florida Non-Profit Corporation) | Rgd mimetic y-aapeptides and methods of use |
| RU2019109456A (ru) | 2013-02-22 | 2019-04-10 | ЭББВИ СТЕМСЕНТРКС ЭлЭлСи | Новые конъюгаты антител и их применения |
| JP2016538318A (ja) | 2013-08-28 | 2016-12-08 | ステムセントリックス, インコーポレイテッド | 新規sez6モジュレーターおよび使用方法 |
| WO2015031698A1 (en) | 2013-08-28 | 2015-03-05 | Stem Centrx, Inc. | Site-specific antibody conjugation methods and compositions |
| WO2015031084A1 (en) | 2013-08-28 | 2015-03-05 | Jianfeng Cai | Methods of synthesizing y-aapeptides, y-aapeptide building blocks, y-aapeptide libraries, and y-aapeptide inhibitors of ab40 aggregates |
| WO2015065954A1 (en) | 2013-11-04 | 2015-05-07 | Pfizer, Inc. | Anti-efna4 antibody-drug conjugates |
| KR20170008202A (ko) | 2014-02-21 | 2017-01-23 | 애브비 스템센트알엑스 엘엘씨 | 흑색종에 사용하기 위한 항-dll3 항체 및 약물 접합체 |
| AU2015240599B2 (en) | 2014-04-04 | 2020-11-19 | Bionomics, Inc. | Humanized antibodies that bind LGR5 |
| HRP20210292T1 (hr) | 2014-04-30 | 2021-04-16 | Pfizer Inc. | Anti-ptk7 protutijelo-lijek konjugati |
| EP3432925A4 (en) | 2016-03-22 | 2019-11-06 | Bionomics Limited | ADMINISTRATION OF A MONOCLONAL ANTI-LGR5 ANTIBODY |
| EP3600422B1 (en) * | 2017-03-31 | 2023-10-18 | The Regents of the University of California | Compositions for use in methods for targeting and killing alpha-v beta-3-positive cancer stem cells (cscs) and treating drug resistant cancers |
| EP3883610A4 (en) | 2018-11-20 | 2022-11-02 | Cornell University | MACROCYCLIC COMPLEXES OF RADIONUCLIDES AND THEIR USE IN CANCER RADIATION THERAPY |
| CN113874392B (zh) | 2019-03-28 | 2025-10-21 | 丹尼斯科美国公司 | 工程化抗体 |
| US20230203191A1 (en) | 2020-03-30 | 2023-06-29 | Danisco Us Inc | Engineered antibodies |
| KR102304832B1 (ko) * | 2020-08-12 | 2021-09-24 | 영남대학교 산학협력단 | 암 세포의 증식을 억제하는 펩티드 fnin3 및 이의 용도 |
| JP7439808B2 (ja) * | 2021-09-17 | 2024-02-28 | 株式会社プロテリアル | 断線検知方法および断線検知装置 |
| EP4554619A1 (en) | 2022-07-15 | 2025-05-21 | Danisco US Inc. | Methods for producing monoclonal antibodies |
| EP4637731A1 (en) | 2022-12-21 | 2025-10-29 | Gilead Sciences, Inc. | Combination therapy for treating cancer |
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|---|---|---|---|---|
| US4474893A (en) * | 1981-07-01 | 1984-10-02 | The University of Texas System Cancer Center | Recombinant monoclonal antibodies |
| US4714681A (en) * | 1981-07-01 | 1987-12-22 | The Board Of Reagents, The University Of Texas System Cancer Center | Quadroma cells and trioma cells and methods for the production of same |
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| CA2397665A1 (en) * | 2000-01-24 | 2001-07-26 | Merck & Co., Inc. | Alpha v integrin receptor antagonists |
| JP2003529356A (ja) * | 2000-04-03 | 2003-10-07 | ブリストル−マイヤーズ スクイブ カンパニー | インテグリン媒介性の細胞−細胞相互作用をモジュレートするための方法及び組成物 |
| US20040254211A1 (en) * | 2000-09-14 | 2004-12-16 | Arison Byron H | Alpha v integrin receptor antagonists |
-
2003
- 2003-03-04 JP JP2003574230A patent/JP2005533001A/ja active Pending
- 2003-03-04 WO PCT/US2003/006684 patent/WO2003075957A1/en not_active Ceased
- 2003-03-04 AU AU2003217930A patent/AU2003217930A1/en not_active Abandoned
- 2003-03-04 CA CA002478239A patent/CA2478239A1/en not_active Abandoned
- 2003-03-04 US US10/379,189 patent/US20040001835A1/en not_active Abandoned
- 2003-03-04 EP EP03713905A patent/EP1487492A4/en not_active Withdrawn
-
2008
- 2008-01-09 US US11/971,675 patent/US20090148459A1/en not_active Abandoned
-
2009
- 2009-02-19 AU AU2009200666A patent/AU2009200666A1/en not_active Abandoned
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