JP2005532079A5 - - Google Patents

Download PDF

Info

Publication number
JP2005532079A5
JP2005532079A5 JP2005505090A JP2005505090A JP2005532079A5 JP 2005532079 A5 JP2005532079 A5 JP 2005532079A5 JP 2005505090 A JP2005505090 A JP 2005505090A JP 2005505090 A JP2005505090 A JP 2005505090A JP 2005532079 A5 JP2005532079 A5 JP 2005532079A5
Authority
JP
Japan
Prior art keywords
cells
cell surface
differentiated
glial cells
neun
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2005505090A
Other languages
English (en)
Japanese (ja)
Other versions
JP4823689B2 (ja
JP2005532079A (ja
Filing date
Publication date
Priority claimed from US10/406,817 external-priority patent/US7285415B2/en
Application filed filed Critical
Publication of JP2005532079A publication Critical patent/JP2005532079A/ja
Publication of JP2005532079A5 publication Critical patent/JP2005532079A5/ja
Application granted granted Critical
Publication of JP4823689B2 publication Critical patent/JP4823689B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2005505090A 2002-07-11 2003-07-11 再ミエリン化および脊髄損傷の治療のためのヒト胚性幹細胞に由来するオリゴデンドロサイト Expired - Lifetime JP4823689B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US39538202P 2002-07-11 2002-07-11
US60/395,382 2002-07-11
US10/406,817 US7285415B2 (en) 2002-07-11 2003-04-04 Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury
US10/406,817 2003-04-04
PCT/IB2003/003539 WO2004007696A2 (en) 2002-07-11 2003-07-11 Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011047716A Division JP5514756B2 (ja) 2002-07-11 2011-03-04 再ミエリン化および脊髄損傷の治療のためのヒト胚性幹細胞に由来するオリゴデンドロサイト

Publications (3)

Publication Number Publication Date
JP2005532079A JP2005532079A (ja) 2005-10-27
JP2005532079A5 true JP2005532079A5 (enExample) 2006-09-07
JP4823689B2 JP4823689B2 (ja) 2011-11-24

Family

ID=30118507

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2005505090A Expired - Lifetime JP4823689B2 (ja) 2002-07-11 2003-07-11 再ミエリン化および脊髄損傷の治療のためのヒト胚性幹細胞に由来するオリゴデンドロサイト
JP2011047716A Expired - Fee Related JP5514756B2 (ja) 2002-07-11 2011-03-04 再ミエリン化および脊髄損傷の治療のためのヒト胚性幹細胞に由来するオリゴデンドロサイト

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2011047716A Expired - Fee Related JP5514756B2 (ja) 2002-07-11 2011-03-04 再ミエリン化および脊髄損傷の治療のためのヒト胚性幹細胞に由来するオリゴデンドロサイト

Country Status (8)

Country Link
US (1) US7285415B2 (enExample)
EP (2) EP2273268A3 (enExample)
JP (2) JP4823689B2 (enExample)
CN (2) CN1852971B (enExample)
AU (1) AU2003250477B2 (enExample)
CA (1) CA2489203C (enExample)
GB (1) GB2407822B (enExample)
WO (1) WO2004007696A2 (enExample)

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6667176B1 (en) 2000-01-11 2003-12-23 Geron Corporation cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells
US7410798B2 (en) 2001-01-10 2008-08-12 Geron Corporation Culture system for rapid expansion of human embryonic stem cells
US20050042749A1 (en) 2001-05-16 2005-02-24 Carpenter Melissa K. Dopaminergic neurons and proliferation-competent precursor cells for treating Parkinson's disease
AU2001263199B2 (en) 2000-05-17 2004-09-16 Asterias Biotherapeutics, Inc. Neural progenitor cell populations
US7250294B2 (en) 2000-05-17 2007-07-31 Geron Corporation Screening small molecule drugs using neural cells differentiated from human embryonic stem cells
CA2476376C (en) 2002-02-15 2014-10-21 Cornell Research Foundation, Inc. Myelination of congenitally dysmyelinated forebrains using oligodendrocyte progenitor cells
US20050101014A1 (en) * 2002-07-11 2005-05-12 Keirstead Hans S. Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury
EP2457999B1 (en) 2002-12-16 2018-10-17 Technion Research & Development Foundation Ltd. Culture medium for pluripotent stem cells
US8518390B2 (en) 2003-06-27 2013-08-27 Advanced Technologies And Regenerative Medicine, Llc Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells
CA2530421C (en) 2003-06-27 2015-04-21 Ethicon, Incorporated Repair and regeneration of ocular tissue using postpartum-derived cells
US8790637B2 (en) 2003-06-27 2014-07-29 DePuy Synthes Products, LLC Repair and regeneration of ocular tissue using postpartum-derived cells
US7875272B2 (en) * 2003-06-27 2011-01-25 Ethicon, Incorporated Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells
US9572840B2 (en) 2003-06-27 2017-02-21 DePuy Synthes Products, Inc. Regeneration and repair of neural tissue using postpartum-derived cells
US8491883B2 (en) * 2003-06-27 2013-07-23 Advanced Technologies And Regenerative Medicine, Llc Treatment of amyotrophic lateral sclerosis using umbilical derived cells
US9592258B2 (en) 2003-06-27 2017-03-14 DePuy Synthes Products, Inc. Treatment of neurological injury by administration of human umbilical cord tissue-derived cells
AR046076A1 (es) * 2003-07-18 2005-11-23 Otsuka Pharma Co Ltd Procedimiento para obtener una poblacion homogenea de celulas precursoras de oligodendrocitos y poblacion obtenida
AU2004276316A1 (en) * 2003-09-24 2005-04-07 The Board Of Trustees Of The Leland Stanford Junior University IGF-1 instructs multipotent adult CNS neural stem cells to an oligodendroglial lineage
US20060166361A1 (en) * 2004-12-21 2006-07-27 Agnieszka Seyda Postpartum cells derived from placental tissue, and methods of making, culturing, and using the same
US20060153815A1 (en) * 2004-12-21 2006-07-13 Agnieszka Seyda Tissue engineering devices for the repair and regeneration of tissue
WO2006101548A2 (en) * 2004-12-21 2006-09-28 Ethicon, Inc. Postpartum cells derived from umbilical cord tissue, and methods of making, culturing, and using the same
JP5340599B2 (ja) 2004-12-23 2013-11-13 エシコン・インコーポレイテッド 臍帯組織由来産褥細胞ならびにその製造方法および使用方法
EP1835924B1 (en) 2004-12-23 2013-08-21 Ethicon, Incorporated Treatment of parkinson's disease and related disorders using postpartum derived cells
AU2006262369B2 (en) 2005-06-22 2012-07-05 Asterias Biotherapeutics, Inc. Suspension culture of human embryonic stem cells
EP1962719A4 (en) 2005-08-29 2011-05-04 Technion Res And Dev Of Foundation Ltd MEDIA FOR BREEDING STEM CELLS
EP2368973A1 (en) 2005-10-13 2011-09-28 Anthrogenesis Corporation Production Of Oligodendrocytes From Placenta-Derived Stem Cells
PL1971681T3 (pl) * 2005-12-16 2018-01-31 Depuy Synthes Products Inc Kompozycje oraz sposoby do hamowania niepożądanej odpowiedzi immunologicznej w przypadku transplantacji z brakiem zgodności tkankowej
JP5179376B2 (ja) * 2005-12-19 2013-04-10 エシコン・インコーポレイテッド ローラーボトルでの分娩後取り出し細胞の体外増殖
WO2007076522A2 (en) * 2005-12-28 2007-07-05 Ethicon, Incorporated Treatment of peripheral vascular disease using postpartum-derived cells
US9125906B2 (en) 2005-12-28 2015-09-08 DePuy Synthes Products, Inc. Treatment of peripheral vascular disease using umbilical cord tissue-derived cells
AP2949A (en) 2006-03-07 2014-07-31 Shroff Geeta Compositions comprising human embryonic stem cellsand their derivatives, methods of use, and method s of preparation
US20080095750A1 (en) * 2006-05-10 2008-04-24 Pennington Biomedical Research Center, Louisiana State University System Use of adipose-derived stem cells for treatment of leukodystrophies
DK3441459T3 (da) 2006-08-02 2021-06-07 Technion Res & Dev Foundation Fremgangsmåder til ekspansion af embryonale stamceller i en suspensionskultur
EP2064319B1 (en) 2006-08-28 2017-02-22 Yeda Research and Development Co. Ltd. Methods of generating glial and neuronal cells and use of same for the treatment of medical conditions of the cns
JP5323845B2 (ja) * 2007-10-05 2013-10-23 エシコン・インコーポレイテッド ヒト臍帯組織由来細胞を用いた腎組織の修復および再建
US8236538B2 (en) * 2007-12-20 2012-08-07 Advanced Technologies And Regenerative Medicine, Llc Methods for sterilizing materials containing biologically active agents
US8227247B2 (en) * 2007-12-20 2012-07-24 Wisconsin Alumni Research Foundation Method of generating myelinating oligodendrocytes
EP2240536B1 (en) 2008-01-30 2019-09-04 Asterias Biotherapeutics, Inc. Synthetic surfaces for culturing stem cell derived oligodendrocyte progenitor cells
CA2723382A1 (en) 2008-05-08 2009-11-12 University Of Rochester Treating myelin diseases with optimized cell preparations
CN107095883A (zh) * 2008-09-04 2017-08-29 Abt控股公司 干细胞预防神经元顶梢枯死的用途
CA2747794C (en) 2008-12-19 2018-10-30 Advanced Technologies And Regenerative Medicine, Llc Treatment of lung and pulmonary diseases and disorders
EP2379089B1 (en) * 2008-12-19 2019-04-17 DePuy Synthes Products, Inc. Regeneration and repair of neural tissue following injury
US10179900B2 (en) * 2008-12-19 2019-01-15 DePuy Synthes Products, Inc. Conditioned media and methods of making a conditioned media
CA2747757C (en) * 2008-12-19 2020-11-03 Ethicon, Incorporated Umbilical cord tissue derived cells for treating neuropathic pain and spasticity
CN102498204B (zh) 2009-03-26 2015-02-04 德普伊新特斯产品有限责任公司 人脐带组织细胞作为用于阿尔茨海默病的疗法
WO2010151782A1 (en) * 2009-06-25 2010-12-29 Geron Corporation Differentiated pluripotent stem cell progeny depleted of extraneous phenotypes
EP2499236B1 (en) 2009-11-12 2020-01-01 Technion Research & Development Foundation Ltd. Culture media, cell cultures and methods of culturing pluripotent stem cells in an undifferentiated state
KR20120107113A (ko) * 2009-12-17 2012-09-28 사노피 수초 염기성 단백질 프로모터(mbp-luci)의 조절 하에 루시페라제를 발현하는 동물 모델 및 생물발광 생체내 영상화를 위한 상기 동물 모델의 용도
CN101735983B (zh) * 2009-12-29 2011-07-27 中国人民解放军第三军医大学 少突胶质前体细胞的分离纯化方法
WO2011159797A2 (en) 2010-06-15 2011-12-22 Cellular Dynamics International, Inc. A compendium of ready-built stem cell models for interrogation of biological response
US8765470B2 (en) 2010-08-04 2014-07-01 Cellular Dynamics International, Inc. Reprogramming immortalized B-cells to induced pluripotent stem cells
WO2012058243A2 (en) * 2010-10-26 2012-05-03 Case Western Reserve University Cell fate conversion of differentiated somatic cells into glial cells
GB2502704B (en) 2010-11-15 2019-12-04 Accelerated Biosciences Corp Generation of neural stem cells from human trophoblast stem cells
US20140329314A1 (en) 2011-03-29 2014-11-06 Christopher O'Sullivan Enriched populations of cardiomyocyte lineage cells from pluripotent stem cells
CN102899285A (zh) * 2011-07-29 2013-01-30 复旦大学 一种体外诱导胚胎干细胞分化成为神经细胞方法
EP2739972B1 (en) * 2011-08-07 2018-07-04 Kadimastem Ltd. Method of identifying agents that affect maturation, survival and myelination
CN104837987B (zh) 2011-12-23 2018-10-02 德普伊新特斯产品公司 人脐带组织来源的细胞的检测
US20150159133A1 (en) * 2012-06-11 2015-06-11 Lonza Walkersville, Inc. Method of in vitro differentiation of motor neuron progenitors (mnps) from human induced pluripotent stem cells and cryopreservation of mnps
CN104919095B (zh) * 2012-12-19 2017-06-30 加利福尼亚大学董事会 用于测定髓鞘形成的微柱阵列
US9270268B2 (en) * 2013-01-02 2016-02-23 International Business Machines Corporation Compensated impedance calibration circuit
EP2954046B1 (en) 2013-02-06 2025-10-15 University Of Rochester Induced pluripotent cell-derived oligodendrocyte progenitor cells for the treatment of myelin disorders
US9850465B2 (en) 2013-02-27 2017-12-26 The Regents Of The University Of California Generation of thymic epithelial progenitor cells in vitro
JP2016520291A (ja) * 2013-03-14 2016-07-14 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア invitroでの内側神経節隆起前駆細胞の作製
US10202580B2 (en) * 2014-01-21 2019-02-12 Japan Science And Technology Agency Adult oligodendrocyte-type 2 astrocyte progenitor cell production method
CA2945393C (en) 2014-04-24 2021-03-23 Board Of Regents, The University Of Texas System Application of induced pluripotent stem cells to generate adoptive cell therapy products
WO2016101017A1 (en) 2014-12-24 2016-06-30 Neuorphan Pty Ltd Improvements in oligodendroglial cell culturing methods and in methods for treating neurodegenerative disorders by using thyroid hormones or analogues
US9724432B2 (en) 2015-04-30 2017-08-08 University Of Rochester Non-human mammal model of human degenerative disorder, uses thereof, and method of treating human degenerative disorder
US10286009B2 (en) * 2015-05-16 2019-05-14 Asterias Biotherapeutics, Inc. Pluripotent stem cell-derived oligodendrocyte progenitor cells for the treatment of spinal cord injury
EP3334414A4 (en) * 2015-08-15 2019-03-20 Asterias Biotherapeutics, Inc. OLIGODY DROCYTE STEM CELL PREPARATION CELLS FOR THE TREATMENT OF WHITE STROKE
MX364892B (es) 2015-10-31 2019-05-10 Io Therapeutics Inc Tratamiento de trastornos del sistema nervioso utilizando combinaciones de agonistas de rxr y hormonas tiroideas.
WO2017147501A1 (en) * 2016-02-25 2017-08-31 Massachusetts Institute Of Technology Neuronal axon mimetics for in vitro analysis of neurological diseases, myelination, and drug screening
US11920155B2 (en) 2016-03-30 2024-03-05 Asterias Biotherapeutics, Inc. Oligodendrocyte progenitor cell compositions
IL251134B (en) * 2016-05-17 2018-03-29 Sheena Haim A system and method for monitoring and managing laboratory procedures
EP3518945A4 (en) * 2016-09-14 2020-04-22 Asterias Biotherapeutics, Inc. PROGENITOR CELLS OF OLIGODENDROCYTES DERIVED FROM PLURIPOTENT STEM CELLS FOR THE TREATMENT OF SPINAL MARROW DAMAGE
JPWO2018164133A1 (ja) * 2017-03-08 2020-01-23 公立大学法人横浜市立大学 細胞選別法
CN110913689A (zh) 2017-05-10 2020-03-24 罗切斯特大学 治疗神经精神病症的方法
WO2018208909A1 (en) 2017-05-10 2018-11-15 Massachusetts Institute Of Technolgy Cell-mimetic device
CA3006897A1 (en) * 2017-08-04 2019-02-04 University Health Network Generation of oligodendrogenic neural progenitor cells
US12090252B2 (en) 2017-09-14 2024-09-17 Riken Method for producing retinal tissues
US12365872B2 (en) 2018-09-19 2025-07-22 Lineage Cell Therapeutics, Inc. Methods for differentiating pluripotent stem cells in dynamic suspension culture
US11603518B2 (en) 2019-01-23 2023-03-14 Asterias Biotherapeutics, Inc. Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells
CN110669734A (zh) * 2019-10-31 2020-01-10 宁夏医科大学 一种用于解救纤粘连蛋白聚合体抑制髓鞘再生的培养体系及其应用
CN114107207B (zh) * 2021-11-26 2023-07-21 内蒙古大学 诱导神经干细胞分化的组合物及方法和用途
US20240382529A1 (en) * 2022-01-28 2024-11-21 Asterias Biotherapeutics, Inc. Compositions and methods for treating spinal cord injuries
CN114262686B (zh) * 2022-03-02 2022-06-24 深圳市夏同生物医药科技有限公司 一种少突胶质细胞的制备方法及应用

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US19046A (en) * 1858-01-05 Shears fob
GB2197915B (en) 1986-11-19 1990-11-14 Rolls Royce Plc Improvements in or relating to fluid bearings
US5851832A (en) 1991-07-08 1998-12-22 Neurospheres, Ltd. In vitro growth and proliferation of multipotent neural stem cells and their progeny
US5750376A (en) * 1991-07-08 1998-05-12 Neurospheres Holdings Ltd. In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny
US5885584A (en) 1991-08-05 1999-03-23 Boehringer Mannheim Gmbh Regeneration of oligodendrocytes
US5849553A (en) 1992-07-27 1998-12-15 California Institute Of Technology Mammalian multipotent neural stem cells
US5654183A (en) 1992-07-27 1997-08-05 California Institute Of Technology Genetically engineered mammalian neural crest stem cells
US5693482A (en) 1992-07-27 1997-12-02 California Institute Of Technology Neural chest stem cell assay
US5766948A (en) 1993-01-06 1998-06-16 The Regents Of The University Of California Method for production of neuroblasts
JP3044689B2 (ja) 1994-10-14 2000-05-22 日本ゼオン株式会社 感光性エラストマー組成物及び感光性ゴム版
US5843780A (en) 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
EP0731108A1 (en) 1995-03-10 1996-09-11 Boehringer Mannheim Gmbh Method of manufacturing a therapeutic agent for the regeneration of oligodendrocytes
US5830651A (en) 1995-06-01 1998-11-03 Signal Pharmaceuticals, Inc. Human oligodendroglial progenitor cell line
WO1997007200A1 (en) 1995-08-16 1997-02-27 The Board Of Trustees Of The Leland Stanford Junior University Adult oligodendrocyte precursor cell compositions and methods
CA2247912A1 (en) 1996-03-04 1997-09-12 University Of Medicine & Dentistry Of New Jersey Genetically engineered primary oligodendrocytes for transplantation-mediated gene delivery in the central nervous system
US5869243A (en) 1996-03-05 1999-02-09 Rhode Island Hospital Immortalized hepatocytes
US5753506A (en) 1996-05-23 1998-05-19 Cns Stem Cell Technology, Inc. Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals
US5840253A (en) 1996-06-20 1998-11-24 Cytek Development Inc Cell wash apparatus
FI990655A7 (fi) 1996-10-01 1999-06-01 Geron Corp Ihmistelomeraasin katalyyttinen alayksikkö
EP0986635A4 (en) 1997-01-10 2001-11-07 Life Technologies Inc SERUM SUBSTITUTE FOR EMBRYONIC STEM CELLS
US6245564B1 (en) 1997-01-23 2001-06-12 Cornell Research Foundation, Inc. Method for separating cells
US6090622A (en) 1997-03-31 2000-07-18 The Johns Hopkins School Of Medicine Human embryonic pluripotent germ cells
US6361996B1 (en) 1997-05-07 2002-03-26 University Of Utah Research Foundation Neuroepithelial stem cells and glial-restricted intermediate precursors
CA2294737A1 (en) 1997-07-04 1999-01-14 University Of Utah Research Foundation Neuron-restricted precursor cells
US6235527B1 (en) 1997-11-29 2001-05-22 University Of Utah Research Foundation Lineage restricted glial precursors from the central nervous system
US5852832A (en) 1997-08-20 1998-12-29 Voigt; Tricia Anne Portable toilet seat
US5968829A (en) 1997-09-05 1999-10-19 Cytotherapeutics, Inc. Human CNS neural stem cells
EP1025204A4 (en) 1997-10-23 2001-02-28 Geron Corp Methods and materials for the growth of primate-derived primordial stem cells
CA2253078C (en) 1997-10-28 2001-05-01 John D. Steeves Immunological composition and its method of use to transiently disrupt mammalian central nervous system myelin to promote neuronal regeneration
US8263402B1 (en) 1998-10-19 2012-09-11 Cornell Research Foundation, Inc. Method for isolating and purifying oligodendrocytes and oligodendrocyte progenitor cells
US6667176B1 (en) 2000-01-11 2003-12-23 Geron Corporation cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells
US6238922B1 (en) 1999-02-26 2001-05-29 Stemcells, Inc. Use of collagenase in the preparation of neural stem cell cultures
WO2001023555A1 (en) 1999-09-27 2001-04-05 Chugai Seiyaku Kabushiki Kaisha Method of prolonging normal cell life span
CA2388736A1 (en) 1999-10-22 2001-04-26 Washington University Oligodendrocyte cell cultures and methods for their preparation and use
WO2001051610A1 (en) 2000-01-14 2001-07-19 Bresagen Limited Ectoderm cell production
EP2453010A1 (en) 2000-03-14 2012-05-16 ES Cell International Pte Ltd. Neural progenitor cells derived from embryonic stem cells
AU2001263199B2 (en) 2000-05-17 2004-09-16 Asterias Biotherapeutics, Inc. Neural progenitor cell populations
JP4795616B2 (ja) 2000-06-20 2011-10-19 イーエス・セル・インターナショナル・プライヴェート・リミテッド Bmp−2経路アンタゴニストの存在下においてes細胞を培養することによって胚性幹細胞の分化をコントロールする方法
JP2004521877A (ja) 2000-11-22 2004-07-22 ジェロン コーポレイション 多能性幹細胞の同種移植片の寛容化
US6921665B2 (en) 2000-11-27 2005-07-26 Roslin Institute (Edinburgh) Selective antibody targeting of undifferentiated stem cells
US6576464B2 (en) 2000-11-27 2003-06-10 Geron Corporation Methods for providing differentiated stem cells
US6887706B2 (en) 2001-10-03 2005-05-03 Wisconsin Alumni Research Foundation Method of in vitro differentiation of transplantable neural precursor cells from primate embryonic stem cells
EP1463803B1 (en) 2001-12-07 2018-02-14 Asterias Biotherapeutics, Inc. Hematopoietic cells from human embryonic stem cells
US20030113910A1 (en) 2001-12-18 2003-06-19 Mike Levanduski Pluripotent stem cells derived without the use of embryos or fetal tissue
AU2003253928A1 (en) * 2002-07-12 2004-02-02 Emory University Methods and transgenic mouse model for identifying and modulating factors involved in the production of reactive oxygen intermediates

Similar Documents

Publication Publication Date Title
JP2005532079A5 (enExample)
AU2002258477A1 (en) Use of rna interference for the creation of lineage specific es and other undifferentiated cells and production of differentiated cells in vitro by co-culture
NZ569543A (en) Means and methods for influencing the stability of antibody producing cells
JP2008518616A5 (enExample)
WO2007050043A3 (en) Methods of specifying mesodermal, endodermal and mesoendodermal cell fates
WO2007077217A3 (en) Oligopeptide-free cell culture media
GB2423934A (en) Extracellular matrix composite materials, and manufacture and use thereof
EP2415480A3 (en) Methods for Regulation of Stem Cells
EP4223769A3 (en) Nuclear reprogramming factor
GB2449772A (en) Large scale production of stem cells
BR0312764A (pt) Cardiomiócitos funcionais originados de células-tronco embrionárias humanas
WO2004020601A3 (en) Neurogenesis from hepatic stem cells
WO2004087870A3 (en) Neuronal cell lineages and methods of production thereof
AU310077S (en) Ink cartridge
PT1487926E (pt) Corantes cerâmicos sob a forma de suspensões nanometricas
WO2002064666A3 (de) Polyphosphazen-haltige substrate als matrize und mit mikrostrukturierter oberfläche
NZ605088A (en) Il-13 producing tr1-like cells and use thereof
ATE340253T1 (de) Zellkonstrukte erhältlich aus mesenchymalen stammzellen und davon ableitbaren zellen und ihre verwendung
JP2007001822A5 (enExample)
TW200708581A (en) Catalyst ink, process for making catalyst ink and for preparing catalyst coated membranes
EP2341147A3 (en) Preprimitive streak and mesendoderm cells
CN115605583A (zh) 一种诱导胶质细胞转分化为功能性神经元的方法及其应用
CN202697969U (zh) 一种配对手环
BR0014489B1 (pt) processo de produÇço de adenovÍrus, e, kit.
AU3612099A (en) Complex formed by a peptide and a major histocompatibility complex at the surface of phages