JP2005530819A5 - - Google Patents

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Publication number
JP2005530819A5
JP2005530819A5 JP2004512660A JP2004512660A JP2005530819A5 JP 2005530819 A5 JP2005530819 A5 JP 2005530819A5 JP 2004512660 A JP2004512660 A JP 2004512660A JP 2004512660 A JP2004512660 A JP 2004512660A JP 2005530819 A5 JP2005530819 A5 JP 2005530819A5
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JP
Japan
Prior art keywords
bone
composition
composition according
growth
treatment comprises
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004512660A
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English (en)
Japanese (ja)
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JP2005530819A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2003/013696 external-priority patent/WO2003105752A2/en
Publication of JP2005530819A publication Critical patent/JP2005530819A/ja
Publication of JP2005530819A5 publication Critical patent/JP2005530819A5/ja
Pending legal-status Critical Current

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JP2004512660A 2002-05-02 2003-05-02 一酸化窒素を放出するビスホスホネート結合体(no−ビスホスホネート)を使用して骨増殖を刺激するための、方法および組成物 Pending JP2005530819A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37789802P 2002-05-02 2002-05-02
PCT/US2003/013696 WO2003105752A2 (en) 2002-05-02 2003-05-02 Methods and compositions for stimulating bone growth using nitric oxide releasing bisphosphonate conjugates (no-bisphosphonate)

Publications (2)

Publication Number Publication Date
JP2005530819A JP2005530819A (ja) 2005-10-13
JP2005530819A5 true JP2005530819A5 (https=) 2006-06-22

Family

ID=29736069

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004512660A Pending JP2005530819A (ja) 2002-05-02 2003-05-02 一酸化窒素を放出するビスホスホネート結合体(no−ビスホスホネート)を使用して骨増殖を刺激するための、方法および組成物

Country Status (6)

Country Link
US (2) US7288535B2 (https=)
EP (1) EP1539185A4 (https=)
JP (1) JP2005530819A (https=)
AU (1) AU2003231255A1 (https=)
CA (1) CA2485090A1 (https=)
WO (1) WO2003105752A2 (https=)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6376476B1 (en) * 1996-12-13 2002-04-23 Zymogenetics Corporation Isoprenoid pathway inhibitors for stimulating bone growth
US8114841B2 (en) * 2004-10-14 2012-02-14 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhPDGF-BB and a biocompatible matrix
US7473678B2 (en) * 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
US8071574B2 (en) * 2005-02-22 2011-12-06 John Dennis Bobyn Implant improving local bone formation
ES2427993T3 (es) * 2006-02-09 2013-11-05 Biomimetic Therapeutics, Llc Composiciones y métodos para el tratamiento de hueso
CA2656278C (en) 2006-06-30 2016-02-09 Biomimetic Therapeutics, Inc. Compositions and methods for treating rotator cuff injuries
US9161967B2 (en) * 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
US8106008B2 (en) 2006-11-03 2012-01-31 Biomimetic Therapeutics, Inc. Compositions and methods for arthrodetic procedures
EP2259807B1 (en) * 2008-02-07 2013-04-24 Biomimetic Therapeutics, Inc. Compositions for distraction osteogenesis
KR20110067035A (ko) * 2008-09-09 2011-06-20 바이오미메틱 세라퓨틱스, 인크. 건 및 인대 손상의 치료를 위한 혈소판-유래 성장 인자 조성물 및 방법
WO2010102266A1 (en) * 2009-03-05 2010-09-10 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods for the treatment of osteochondral defects
WO2011088318A1 (en) 2010-01-15 2011-07-21 University Of Medicine And Dentistry Of New Jersey Use of vanadium compounds to accelerate bone healing
CN102811622A (zh) 2010-02-22 2012-12-05 生物模拟治疗公司 用于治疗腱病的血小板衍生生长因子组合物和方法
US8877221B2 (en) 2010-10-27 2014-11-04 Warsaw Orthopedic, Inc. Osteoconductive matrices comprising calcium phosphate particles and statins and methods of using the same
US9107983B2 (en) 2010-10-27 2015-08-18 Warsaw Orthopedic, Inc. Osteoconductive matrices comprising statins
US20140322292A1 (en) 2010-12-10 2014-10-30 Rutgers, The State University Of New Jersey Insulin-mimetics as therapeutic adjuncts for bone regeneration
WO2013006798A1 (en) 2011-07-06 2013-01-10 University Of Medicine And Dentistry Of New Jersey Vandium compounds as therapeutic adjuncts for cartilage regeneration and repair
KR20140048076A (ko) 2010-12-10 2014-04-23 유니버시티 오브 메디신 앤드 덴티스트리 오브 뉴 저지 인슐린 모사 제제 복합재로 코팅된 생체 매립가능한 장치 및 이의 방법
US9308190B2 (en) 2011-06-06 2016-04-12 Warsaw Orthopedic, Inc. Methods and compositions to enhance bone growth comprising a statin
US20170087175A1 (en) * 2015-09-30 2017-03-30 Elwha Llc Nitric oxide-modulating bone-targeting complexes
US20190275160A1 (en) 2016-03-15 2019-09-12 The Regents Of The University Of California Bone-targeting therapeutic conjugate and methods of making and using the same
KR20180115979A (ko) * 2017-04-14 2018-10-24 연세대학교 산학협력단 비스포스포네이트를 포함하는 만성 이식신 기능부전 예방 또는 치료용 조성물

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5121253A (en) * 1990-12-28 1992-06-09 Waintroob Stewart B Visor for a computer terminal display and method
IT1246778B (it) 1991-04-12 1994-11-26 Boehringer Mannheim Italia Nitrosocarbamoil derivati di acidi gem-difosfonici, un processo per la loro preparazione e composizioni farmaceutiche che li contengono
US5118667A (en) * 1991-05-03 1992-06-02 Celtrix Pharmaceuticals, Inc. Bone growth factors and inhibitors of bone resorption for promoting bone formation
US5280040A (en) 1993-03-11 1994-01-18 Zymogenetics, Inc. Methods for reducing bone loss using centchroman derivatives
US5898038A (en) 1996-03-19 1999-04-27 Board Of Regents, The University Of Texas System Treatment of osteoporosis and metabolic bone disorders with nitric oxide substrate and/or donors
US6214812B1 (en) * 1998-04-02 2001-04-10 Mbc Research, Inc. Bisphosphonate conjugates and methods of making and using the same
IT1303672B1 (it) 1998-07-28 2001-02-23 Nicox Sa Sali nitrati di farmaci attivi nei disordini ossei
US6121253A (en) * 1998-11-20 2000-09-19 Merck Frosst Canada & Co. Prostaglandin conjugates for treating or preventing bone disease
AU2900100A (en) 1999-03-05 2000-09-21 Merck Frosst Canada & Co. Methods for inhibiting cathepsin k activity for the treatment of diseases related to bone loss
IT1311924B1 (it) 1999-04-13 2002-03-20 Nicox Sa Composti farmaceutici.
IT1314184B1 (it) 1999-08-12 2002-12-06 Nicox Sa Composizioni farmaceutiche per la terapia di condizioni di stressossidativo

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