JP2005530730A5 - - Google Patents
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- Publication number
- JP2005530730A5 JP2005530730A5 JP2003584041A JP2003584041A JP2005530730A5 JP 2005530730 A5 JP2005530730 A5 JP 2005530730A5 JP 2003584041 A JP2003584041 A JP 2003584041A JP 2003584041 A JP2003584041 A JP 2003584041A JP 2005530730 A5 JP2005530730 A5 JP 2005530730A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- alkoxy
- independently
- amino
- fully halogenated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37167102P | 2002-04-11 | 2002-04-11 | |
| PCT/US2003/011094 WO2003087085A1 (en) | 2002-04-11 | 2003-04-10 | Heterocyclic amide derivatives as cytokine inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005530730A JP2005530730A (ja) | 2005-10-13 |
| JP2005530730A5 true JP2005530730A5 (enExample) | 2006-06-08 |
| JP4578106B2 JP4578106B2 (ja) | 2010-11-10 |
Family
ID=29250721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003584041A Expired - Lifetime JP4578106B2 (ja) | 2002-04-11 | 2003-04-10 | サイトカインインヒビターとしてのヘテロ環式アミド誘導体 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7550461B2 (enExample) |
| EP (1) | EP1497278B1 (enExample) |
| JP (1) | JP4578106B2 (enExample) |
| AT (1) | ATE469142T1 (enExample) |
| AU (1) | AU2003224923A1 (enExample) |
| CA (1) | CA2478232C (enExample) |
| DE (1) | DE60332717D1 (enExample) |
| ES (1) | ES2343787T3 (enExample) |
| WO (1) | WO2003087085A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1497278B1 (en) * | 2002-04-11 | 2010-05-26 | Boehringer Ingelheim Pharmaceuticals Inc. | Heterocyclic amide derivatives as cytokine inhibitors |
| US7078419B2 (en) * | 2003-03-10 | 2006-07-18 | Boehringer Ingelheim Pharmaceuticals, Inc. | Cytokine inhibitors |
| EP1867646A1 (en) * | 2004-05-03 | 2007-12-19 | Boehringer Ingelheim Pharmaceuticals, Inc. | Cytokine inhibitors |
| US7285545B2 (en) | 2004-05-03 | 2007-10-23 | Boehringer Ingelheim Pharmaceuticals, Inc. | Cytokine inhibitors |
| WO2006026235A1 (en) * | 2004-08-25 | 2006-03-09 | Boehringer Ingelheim Pharmaceuticals, Inc. | Cytokine inhibitors |
| WO2006062982A2 (en) * | 2004-12-07 | 2006-06-15 | Locus Pharmaceuticals, Inc. | Urea inhibitors of map kinases |
| US7612200B2 (en) * | 2004-12-07 | 2009-11-03 | Locus Pharmaceuticals, Inc. | Inhibitors of protein kinases |
| EP1838690A2 (en) * | 2004-12-21 | 2007-10-03 | Devgen N.V. | Compounds with kv4 ion channel activity |
| US8957070B2 (en) | 2005-04-20 | 2015-02-17 | Takeda Pharmaceutical Company Limited | Glucokinase activator compounds, methods of activating glucokinase and methods of treating diabetes and obesity |
| CA2635888A1 (en) * | 2006-01-04 | 2007-07-19 | Locus Pharmaceuticals, Inc. | Inhibitors of protein kinases |
| JP5216912B2 (ja) | 2008-04-29 | 2013-06-19 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｃｃｒ１受容体拮抗薬としてのインダゾール化合物 |
| JP5411927B2 (ja) * | 2008-05-06 | 2014-02-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｃｃｒ１アンタゴニストとしてのピラゾール化合物 |
| EP2161266A1 (en) * | 2008-08-22 | 2010-03-10 | EVOTEC Neurosciences GmbH | Benzofuran derivatives as orexin receptor antagonists |
| PE20110854A1 (es) | 2008-09-26 | 2011-12-23 | Boehringer Ingelheim Int | DERIVADOS DE 1-FENIL-1H-PIRAZOLO[3,4-c]PIRIDINA-4-CARBONILAMINA COMO ANTAGONISTAS DE LOS RECEPTORES CCR1 |
| AP2012006204A0 (en) | 2009-10-21 | 2012-04-30 | Boehringer Ingelheim Int | Indazole and pyrazolopyridine compounds as CCR1 receptor antagonists. |
| JP5542214B2 (ja) | 2009-10-27 | 2014-07-09 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｃｃｒ１受容体アンタゴニストとしての複素環化合物 |
| US8871786B2 (en) | 2010-04-30 | 2014-10-28 | Boehringer Ingelheim International Gmbh | Azaindazole amide compounds as CCR1 receptor antagonists |
| US8546442B2 (en) | 2010-12-23 | 2013-10-01 | Boehringer Ingelheim International Gmbh | Pyrazolopiperidine compounds as CCR1 receptor antagonists |
| CN121695288A (zh) | 2020-02-19 | 2026-03-20 | Epizyme股份有限公司 | Setd2抑制剂和相关方法和用途，包括组合疗法 |
| CN117510460B (zh) * | 2023-10-30 | 2026-02-06 | 贵州大学 | 一种含磺酰胺单元的苯并[b]噻吩衍生物、其制备方法及应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4317076A1 (de) * | 1993-05-21 | 1994-11-24 | Bayer Ag | Benzthiophencarbonsäureamid-S-oxide |
| DE19642529A1 (de) * | 1996-10-15 | 1998-04-16 | Bayer Ag | Aminophenolderivate |
| US5994398A (en) * | 1996-12-11 | 1999-11-30 | Elan Pharmaceuticals, Inc. | Arylsulfonamides as phospholipase A2 inhibitors |
| US6579872B1 (en) * | 1998-05-15 | 2003-06-17 | Astrazeneca Ab | Bezamide derivatives for the treatment of diseases mediated by cytokines |
| ATE254105T1 (de) | 1998-09-25 | 2003-11-15 | Astrazeneca Ab | Benzamid-derivate und ihre verwendung als cytokine inhibitoren |
| TR200102817T2 (tr) | 1999-03-12 | 2002-05-21 | Boehringer Ingelheim Pharmaceuticals, Inc. | Antiinflamatuar ajanlar olarak faydalı bileşikler |
| TWI288745B (en) * | 2000-04-05 | 2007-10-21 | Daiichi Seiyaku Co | Ethylenediamine derivatives |
| WO2002012189A1 (en) * | 2000-08-09 | 2002-02-14 | Mitsubishi Pharma Corporation | Fused bicyclic amide compounds and medicinal use thereof |
| MXPA03009000A (es) | 2001-04-13 | 2004-02-12 | Boehringer Ingelheim Pharma | Compuestos benzo-fusionados 1,4-disustituidos. |
| AR034897A1 (es) * | 2001-08-07 | 2004-03-24 | Hoffmann La Roche | Derivados n-monoacilados de o-fenilendiaminas, sus analogos heterociclicos de seis miembros y su uso como agentes farmaceuticos |
| EP1497278B1 (en) * | 2002-04-11 | 2010-05-26 | Boehringer Ingelheim Pharmaceuticals Inc. | Heterocyclic amide derivatives as cytokine inhibitors |
-
2003
- 2003-04-10 EP EP03721619A patent/EP1497278B1/en not_active Expired - Lifetime
- 2003-04-10 ES ES03721619T patent/ES2343787T3/es not_active Expired - Lifetime
- 2003-04-10 JP JP2003584041A patent/JP4578106B2/ja not_active Expired - Lifetime
- 2003-04-10 AT AT03721619T patent/ATE469142T1/de active
- 2003-04-10 AU AU2003224923A patent/AU2003224923A1/en not_active Abandoned
- 2003-04-10 CA CA2478232A patent/CA2478232C/en not_active Expired - Lifetime
- 2003-04-10 WO PCT/US2003/011094 patent/WO2003087085A1/en not_active Ceased
- 2003-04-10 DE DE60332717T patent/DE60332717D1/de not_active Expired - Lifetime
- 2003-04-10 US US10/410,688 patent/US7550461B2/en not_active Expired - Lifetime
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