JP2005528427A - 改善された化学安定性を有する活性物質を含むフィルム型製剤およびその製造方法 - Google Patents

改善された化学安定性を有する活性物質を含むフィルム型製剤およびその製造方法 Download PDF

Info

Publication number
JP2005528427A
JP2005528427A JP2004508779A JP2004508779A JP2005528427A JP 2005528427 A JP2005528427 A JP 2005528427A JP 2004508779 A JP2004508779 A JP 2004508779A JP 2004508779 A JP2004508779 A JP 2004508779A JP 2005528427 A JP2005528427 A JP 2005528427A
Authority
JP
Japan
Prior art keywords
active substance
formulation
cellulose
film
peroxides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004508779A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005528427A5 (enExample
Inventor
ファルケンハウゼン，クリスチャン フォン
ミュラー，ヴァルター
クルンメ，マークス
Original Assignee
エルテーエス ローマン テラピー−ジステーメ アーゲー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by エルテーエス ローマン テラピー−ジステーメ アーゲー filed Critical エルテーエス ローマン テラピー−ジステーメ アーゲー
Publication of JP2005528427A publication Critical patent/JP2005528427A/ja
Publication of JP2005528427A5 publication Critical patent/JP2005528427A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP2004508779A 2002-06-04 2003-05-08 改善された化学安定性を有する活性物質を含むフィルム型製剤およびその製造方法 Pending JP2005528427A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10224612A DE10224612A1 (de) 2002-06-04 2002-06-04 Wirkstoffhaltige filmförmige Zubereitungen mit verbesserter chemischer Stabilität, und Verfahren zu deren Herstellung
PCT/EP2003/004816 WO2003101421A1 (de) 2002-06-04 2003-05-08 Wirkstoffhaltige filmförmige zubereitungen mit verbesserter chemischer stabilität, und verfahren zu deren herstellung

Publications (2)

Publication Number Publication Date
JP2005528427A true JP2005528427A (ja) 2005-09-22
JP2005528427A5 JP2005528427A5 (enExample) 2006-02-16

Family

ID=29594232

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004508779A Pending JP2005528427A (ja) 2002-06-04 2003-05-08 改善された化学安定性を有する活性物質を含むフィルム型製剤およびその製造方法

Country Status (15)

Country Link
US (1) US20050226823A1 (enExample)
EP (1) EP1509201B1 (enExample)
JP (1) JP2005528427A (enExample)
KR (1) KR20050010024A (enExample)
CN (1) CN1658833A (enExample)
AR (1) AR039955A1 (enExample)
AT (1) ATE426400T1 (enExample)
AU (1) AU2003236632B2 (enExample)
BR (1) BR0311663A (enExample)
CA (1) CA2487590C (enExample)
DE (2) DE10224612A1 (enExample)
ES (1) ES2324909T3 (enExample)
RU (1) RU2311900C2 (enExample)
TW (1) TWI344373B (enExample)
WO (1) WO2003101421A1 (enExample)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006528636A (ja) * 2003-07-24 2006-12-21 スミスクライン・ビーチャム・コーポレイション 経口溶解性フィルム
JP2008517935A (ja) * 2004-10-21 2008-05-29 ノバルティス アクチエンゲゼルシャフト ジクロフェナクを含む医薬組成物
JP2008530263A (ja) * 2005-02-09 2008-08-07 ビーエーエスエフ ソシエタス・ヨーロピア ポリビニルピロリドンの安定化法
JP2012214425A (ja) * 2011-04-01 2012-11-08 Nitto Denko Corp ニコチン含有貼付製剤
JP2016216501A (ja) * 2008-08-01 2016-12-22 ザ メディシンズ カンパニー 医薬組成物およびこれを安定化させる方法
WO2019171843A1 (ja) * 2018-03-05 2019-09-12 パナソニックＩｐマネジメント株式会社 化粧料または医療材料

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10361306A1 (de) * 2003-12-24 2005-07-28 Lts Lohmann Therapie-Systeme Ag Wundauflage und Wundschnellverband mit einem vasokonstriktorischen Inhaltsstoff, sowie Herstellungsverfahren hierfür
WO2006135491A2 (en) * 2005-06-08 2006-12-21 Basf Aktiengesellschaft Medicament carrier composition and method of forming a film therefrom
WO2007034287A2 (en) * 2005-09-19 2007-03-29 University Of The Witwatersrand, Johannesburg Oramucosal pharmaceutical dosage form
KR100742432B1 (ko) * 2005-12-27 2007-07-24 한미약품 주식회사 암로디핀 캠실레이트 및 심바스타틴을 포함하는 복합제제,및 이의 제조방법
FR2902655B1 (fr) * 2006-06-23 2008-11-28 Oreal Compositon topique a effet froid
RU2418574C2 (ru) * 2007-02-08 2011-05-20 Медтроник Ксомед Инк. Сольватирующая система и герметик для медицинского применения
JP5138765B2 (ja) * 2008-03-18 2013-02-06 日本たばこ産業株式会社 シガレット主流煙成分吸着剤およびシガレット用フィルタ
ES2699077T3 (es) 2009-06-12 2019-02-07 Sunovion Pharmaceuticals Inc Apomorfina sublingual
EA031156B1 (ru) 2010-12-16 2018-11-30 Суновион Фармасьютикалз Инк. Сублингвальные пленки
CN103788552B (zh) * 2012-10-26 2016-12-21 厦门加岩高分子材料有限公司 聚乙烯醇共混物
SG11201610636VA (en) * 2014-06-20 2017-01-27 Ctc Bio Inc Pharmaceutical preparation containing entecavir as active ingredient, and preparation method therefor
WO2016172095A1 (en) 2015-04-21 2016-10-27 Cynapsus Therapeutics, Inc. Methods of treating parkinson's disease by administration of apomorphine to an oral mucosa
WO2017081725A1 (ja) * 2015-11-09 2017-05-18 花王株式会社 口腔用組成物
US11648212B2 (en) * 2016-02-03 2023-05-16 Intelgenx Corp. Loxapine film oral dosage form
DE102017127452A1 (de) * 2017-11-21 2019-05-23 Lts Lohmann Therapie-Systeme Ag Wasserlösliche Polymerklebschichten
IT201800011125A1 (it) 2018-12-14 2020-06-14 Dpl Pharma S P A Composizioni farmaceutiche orali solide comprendenti matrici monolitiche complesse per la somministrazione cronotropica di medicamenti nel tratto gastroenterico
CN110339118B (zh) * 2019-08-19 2022-08-16 广州明辉化妆品有限公司 具有美白保湿功效的美白霜
SE544672C2 (en) 2020-05-07 2022-10-11 Liw Innovation Ab New compositions for oral or nasal use
IT202000011050A1 (it) 2020-05-14 2021-11-14 Mogon Pharmaceuticals Sagl Composizioni orali solide comprendenti matrici monolitiche composite per la somministrazione cronotropica nel tratto gastroenterico di ingredienti attivi
IT202000011053A1 (it) 2020-05-14 2021-11-14 Int Health Science S R L Composizioni orali solide comprendenti matrici monolitiche composite per la somministrazione cronotropica nel tratto gastroenterico di alimenti, integratori alimentari, nutraceutici, dispositivi medici

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2019275B3 (es) * 1985-10-09 1991-06-16 Desitin Arzneimittel Gmbh Metodo para la produccion de una forma de administracion y de dosificacion para farmacos reactivos u otros principios activos.
US5032384A (en) * 1989-01-27 1991-07-16 Block Drug Company, Inc. Compositions and method for the treatment of disease
IL97930A (en) * 1991-04-23 1996-06-18 Perio Prod Ltd Preparations for whitening two controlled release products that contain a super-oxygen compound
JP2671248B2 (ja) * 1991-10-23 1997-10-29 ブロック・ドラッグ・カンパニー・インコーポレイテッド 薬効または化粧効果成分の浸透性増進方法
AU4327193A (en) * 1992-07-08 1994-01-31 Dianorm-Gerate G. Maierhofer Liposomes, method of preparing them and their use in the preparation of drugs
DE69724424T2 (de) * 1996-05-13 2004-06-24 Novartis Consumer Health S.A. Mundfreisetzungssystem
US6375963B1 (en) * 1999-06-16 2002-04-23 Michael A. Repka Bioadhesive hot-melt extruded film for topical and mucosal adhesion applications and drug delivery and process for preparation thereof
RU2155071C1 (ru) * 1999-08-10 2000-08-27 Мизина Прасковья Георгиевна Способ получения лекарственной фитопленки
JP5753645B2 (ja) * 1999-11-29 2015-07-22 エルテーエス ローマン テラピー−ジステーメ アーゲー 安定性が改善された経皮治療システムおよびそれらの製法
DE10018834A1 (de) * 2000-04-15 2001-10-25 Lohmann Therapie Syst Lts Transdermale oder transmucosale Darreichungsformen mit einer nicotinhaltigen Wirkstoffkombination zur Raucherentwöhnung
DE10107659B4 (de) * 2001-02-19 2008-03-13 Lts Lohmann Therapie-Systeme Ag Mucoadhäsive zerfallsfähige Arzneizubereitung zur Wirkstoffverabreichung in der Veterinär- und Humanmedizin
RU2195545C1 (ru) * 2001-08-14 2002-12-27 Хаминов Николай Иванович Способ изоляции промытых зон в добывающей и нагнетательной скважинах

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006528636A (ja) * 2003-07-24 2006-12-21 スミスクライン・ビーチャム・コーポレイション 経口溶解性フィルム
JP2010120975A (ja) * 2003-07-24 2010-06-03 Glaxosmithkline Llc 経口溶解性フィルム
JP2008517935A (ja) * 2004-10-21 2008-05-29 ノバルティス アクチエンゲゼルシャフト ジクロフェナクを含む医薬組成物
JP2008530263A (ja) * 2005-02-09 2008-08-07 ビーエーエスエフ ソシエタス・ヨーロピア ポリビニルピロリドンの安定化法
JP2016216501A (ja) * 2008-08-01 2016-12-22 ザ メディシンズ カンパニー 医薬組成物およびこれを安定化させる方法
JP2012214425A (ja) * 2011-04-01 2012-11-08 Nitto Denko Corp ニコチン含有貼付製剤
WO2019171843A1 (ja) * 2018-03-05 2019-09-12 パナソニックＩｐマネジメント株式会社 化粧料または医療材料

Also Published As

Publication number Publication date
TW200307566A (en) 2003-12-16
ATE426400T1 (de) 2009-04-15
US20050226823A1 (en) 2005-10-13
AU2003236632B2 (en) 2008-07-31
AU2003236632A1 (en) 2003-12-19
WO2003101421A1 (de) 2003-12-11
AR039955A1 (es) 2005-03-09
TWI344373B (en) 2011-07-01
DE10224612A1 (de) 2003-12-24
BR0311663A (pt) 2005-06-28
CA2487590A1 (en) 2003-12-11
ES2324909T3 (es) 2009-08-19
EP1509201A1 (de) 2005-03-02
EP1509201B1 (de) 2009-03-25
RU2311900C2 (ru) 2007-12-10
CA2487590C (en) 2011-01-11
KR20050010024A (ko) 2005-01-26
RU2004136576A (ru) 2005-08-27
DE50311338D1 (de) 2009-05-07
CN1658833A (zh) 2005-08-24
WO2003101421A8 (de) 2005-04-21

Similar Documents

Publication Publication Date Title
JP2005528427A (ja) 改善された化学安定性を有する活性物質を含むフィルム型製剤およびその製造方法
AU2003240824B9 (en) Transmucosal delivery of cannabinoids
US8735374B2 (en) Oral mucoadhesive dosage form
TWI548426B (zh) 己烯雌酚之劑型及治療方法
EP2519225B1 (en) Melt extruded nicotine thin strips
JP2010519325A (ja) 活性物質の経口投与のための速崩壊性単層膜
CN104519872B (zh) 神经肌肉阻断剂的稳定水性组合物
AU2025205000A1 (en) Apixaban Film Product And Uses Thereof
JP2002012541A (ja) フィルムコーティング組成物およびそれを用いた防臭性固形製剤
EP2213278A1 (de) Pharmazeutische Zubereitung mit verbesserter Stabilität des Wirkstoffs
EP4529918A1 (en) Nicotine oral film agent and preparation method thereof
JP2025522238A (ja) アドレナリンを含む経口薄フィルム剤
JP2006182669A (ja) 口腔内貼付剤
JP2025520925A (ja) 低水分活性を有する経口薄フィルム剤
CN120605262A (zh) 辅酶q10口溶膜

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20051220

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20051220

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20090811

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20091111

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20091118

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20091211

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20100112