JP2005527510A - 癌の治療において一酸化窒素模倣体を使用するための製剤および方法 - Google Patents
癌の治療において一酸化窒素模倣体を使用するための製剤および方法 Download PDFInfo
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- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2009242378A (ja) * | 2008-03-13 | 2009-10-22 | Chiba Univ | シスプラチン効果増強剤及び抗癌剤キット |
| JP2011507968A (ja) * | 2007-12-27 | 2011-03-10 | エイヤーズ ファーマシューティカルズ、インク． | エアロゾル化ニトライトおよび一酸化窒素供与性化合物ならびにそれらの使用 |
| JP2011521908A (ja) * | 2008-05-09 | 2011-07-28 | デューク ユニバーシティ | チオレドキシンが細胞における一酸化窒素放出を調節するという知見に基づく疾患の治療法 |
| WO2012118042A1 (ja) * | 2011-02-28 | 2012-09-07 | 独立行政法人国立循環器病研究センター | 悪性腫瘍転移抑制用医薬 |
| JP2012219050A (ja) * | 2011-04-07 | 2012-11-12 | Nipro Corp | 抗癌剤増感剤 |
| JP2017515800A (ja) * | 2014-04-08 | 2017-06-15 | ザ・メソジスト・ホスピタル | ｉＮＯＳ阻害組成物および乳がん治療薬としてのその使用 |
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| DE10135815A1 (de) * | 2001-07-23 | 2003-02-06 | Bayer Ag | Verwendung von 2-Alkoxyphenyl-substituierten Imidazotriazinonen |
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| US20070135380A1 (en) | 2005-08-12 | 2007-06-14 | Radiorx, Inc. | O-nitro compounds, pharmaceutical compositions thereof and uses thereof |
| AU2012203798B2 (en) * | 2005-08-12 | 2013-11-07 | Northrop Grumman Systems Corporation | O-nitro compounds, pharmaceutical compositons thereof and uses thereof |
| EP2658979B1 (en) | 2010-12-27 | 2018-02-14 | Alexion Pharmaceuticals, Inc. | Compositions comprising natriuretic peptides and methods of use thereof |
| US10052366B2 (en) | 2012-05-21 | 2018-08-21 | Alexion Pharmaceuticsl, Inc. | Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof |
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| MX389350B (es) | 2014-12-05 | 2025-03-19 | Alexion Pharma Inc | Fosfatasas alcalinas recombinantes y usos de las mismas para el tratamiento de convulsiones. |
| US10603361B2 (en) | 2015-01-28 | 2020-03-31 | Alexion Pharmaceuticals, Inc. | Methods of treating a subject with an alkaline phosphatase deficiency |
| KR102644116B1 (ko) | 2015-08-17 | 2024-03-05 | 알렉시온 파마슈티칼스, 인코포레이티드 | 알칼린 포스파타제의 제조 |
| WO2017058822A1 (en) | 2015-09-28 | 2017-04-06 | Alexion Pharmaceuticals, Inc. | Identifying effective dosage regimens for tissue non-specific alkaline phosphatase (tnsalp)-enzyme replacement therapy of hypophosphatasia |
| JP2018533571A (ja) | 2015-10-30 | 2018-11-15 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | 患者の頭蓋縫合早期癒合症を治療するための方法 |
| WO2017155569A1 (en) | 2016-03-08 | 2017-09-14 | Alexion Pharmaceuticals, Inc. | Methods for treating hypophosphatasia in children |
| CA3019726A1 (en) | 2016-04-01 | 2017-10-05 | Alexion Pharmaceuticals, Inc. | Treating muscle weakness with alkaline phosphatases |
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| JP2023504208A (ja) | 2019-12-09 | 2023-02-01 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | アルカリホスファターゼポリペプチド及びその使用方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| LV11542B (en) * | 1995-03-30 | 1997-02-20 | Latvijas Organiskas Sintezes Instituts | Substituted 1,3,9,11-tetraoxa-4,5,7,8-tetraazaundecadien-4,7-dioxides-5,7, preparation and use thereof |
| WO1999003462A1 (en) * | 1997-07-14 | 1999-01-28 | Brigham And Women's Hospital | Modification of nitric oxide activity to treat fas-induced pathologies |
| JP2004508279A (ja) * | 2000-01-26 | 2004-03-18 | シーダース シナイ メディカル センター | 薬剤を異常脳領域及び／又は悪性腫瘍にデリバリーするためにカリウムチャンネル活性化を用いる方法 |
| US20010038832A1 (en) * | 2000-04-11 | 2001-11-08 | Benjamin Bonavida | Nitric oxide and analogues thereof effectuate sensitization of neoplasm and immunologically undesired tissues to cytotoxicity |
| DE60106905T2 (de) * | 2000-04-26 | 2005-12-01 | Cellegy Pharmaceuticals, Inc., South San Francisco | Formulierungen und verfahren zur verwendung von stickstoffmonoxid mimetika gegen einen malignen zellphänotyp |
-
2003
- 2003-03-06 CA CA002478145A patent/CA2478145A1/en not_active Abandoned
- 2003-03-06 JP JP2003572598A patent/JP2005527510A/ja active Pending
- 2003-03-06 AU AU2003208228A patent/AU2003208228A1/en not_active Abandoned
- 2003-03-06 EP EP03706181A patent/EP1492567A1/en not_active Withdrawn
- 2003-03-06 WO PCT/CA2003/000313 patent/WO2003074082A1/en not_active Ceased
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| JP2011507968A (ja) * | 2007-12-27 | 2011-03-10 | エイヤーズ ファーマシューティカルズ、インク． | エアロゾル化ニトライトおよび一酸化窒素供与性化合物ならびにそれらの使用 |
| JP2009242378A (ja) * | 2008-03-13 | 2009-10-22 | Chiba Univ | シスプラチン効果増強剤及び抗癌剤キット |
| JP2011521908A (ja) * | 2008-05-09 | 2011-07-28 | デューク ユニバーシティ | チオレドキシンが細胞における一酸化窒素放出を調節するという知見に基づく疾患の治療法 |
| WO2012118042A1 (ja) * | 2011-02-28 | 2012-09-07 | 独立行政法人国立循環器病研究センター | 悪性腫瘍転移抑制用医薬 |
| JP5948683B2 (ja) * | 2011-02-28 | 2016-07-06 | 国立研究開発法人国立循環器病研究センター | 悪性腫瘍転移抑制用医薬 |
| JP2012219050A (ja) * | 2011-04-07 | 2012-11-12 | Nipro Corp | 抗癌剤増感剤 |
| JP2017515800A (ja) * | 2014-04-08 | 2017-06-15 | ザ・メソジスト・ホスピタル | ｉＮＯＳ阻害組成物および乳がん治療薬としてのその使用 |
| US10420838B2 (en) | 2014-04-08 | 2019-09-24 | The Methodist Hospital | Methods for treating cancer using iNOS-inhibitory compositions |
| JP2020128445A (ja) * | 2014-04-08 | 2020-08-27 | ザ・メソジスト・ホスピタル | ｉＮＯＳ阻害組成物および乳がん治療薬としてのその使用 |
| US11357850B2 (en) | 2014-04-08 | 2022-06-14 | The Methodist Hospital | Methods for treating breast cancer using INOS-inhibitory compositions |
| JP2024128025A (ja) * | 2014-04-08 | 2024-09-20 | ザ・メソジスト・ホスピタル | ｉＮＯＳ阻害組成物および乳がん治療薬としてのその使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003074082A1 (en) | 2003-09-12 |
| EP1492567A1 (en) | 2005-01-05 |
| AU2003208228A1 (en) | 2003-09-16 |
| CA2478145A1 (en) | 2003-09-12 |
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