JP2005526692A - 炭水化物ハプテンの免疫原共役体および凝集タンパク質キャリヤ - Google Patents

炭水化物ハプテンの免疫原共役体および凝集タンパク質キャリヤ Download PDF

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Publication number
JP2005526692A
JP2005526692A JP2003520755A JP2003520755A JP2005526692A JP 2005526692 A JP2005526692 A JP 2005526692A JP 2003520755 A JP2003520755 A JP 2003520755A JP 2003520755 A JP2003520755 A JP 2003520755A JP 2005526692 A JP2005526692 A JP 2005526692A
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JP
Japan
Prior art keywords
conjugate
hapten
carrier
conjugate according
carbohydrate
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Abandoned
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JP2003520755A
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English (en)
Japanese (ja)
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JP2005526692A5 (enExample
Inventor
クランツ,マーク,ジェイ
ロンジェネッカー,ビー.,マイケル
コガンティ,アール.,ラオ
ウォン,チン,チ
Original Assignee
ビオミラ,インコーポレーテッド
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Publication of JP2005526692A publication Critical patent/JP2005526692A/ja
Publication of JP2005526692A5 publication Critical patent/JP2005526692A5/ja
Abandoned legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001169Tumor associated carbohydrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001169Tumor associated carbohydrates
    • A61K39/001172Sialyl-Thomson-nouvelle antigen [sTn]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/0004Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6081Albumin; Keyhole limpet haemocyanin [KLH]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
JP2003520755A 2001-08-14 2002-08-05 炭水化物ハプテンの免疫原共役体および凝集タンパク質キャリヤ Abandoned JP2005526692A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31185001P 2001-08-14 2001-08-14
PCT/US2002/024735 WO2003015796A1 (en) 2001-08-14 2002-08-05 Imunogenic conjugate of carbohydrate haptens and aggregated protein carrier

Publications (2)

Publication Number Publication Date
JP2005526692A true JP2005526692A (ja) 2005-09-08
JP2005526692A5 JP2005526692A5 (enExample) 2006-01-12

Family

ID=23208785

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003520755A Abandoned JP2005526692A (ja) 2001-08-14 2002-08-05 炭水化物ハプテンの免疫原共役体および凝集タンパク質キャリヤ

Country Status (6)

Country Link
US (1) US20040247608A1 (enExample)
EP (1) EP1429785A4 (enExample)
JP (1) JP2005526692A (enExample)
CN (1) CN1543350A (enExample)
CA (1) CA2454853A1 (enExample)
WO (1) WO2003015796A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013532135A (ja) * 2010-06-09 2013-08-15 北京大学 シアル酸(α−(2→6))−D−ピラノース誘導体及びその合成方法と応用
JP2017532310A (ja) * 2014-09-15 2017-11-02 オービーアイ ファーマ,インコーポレイテッド 免疫原性/治療用糖コンジュゲート組成物およびその使用

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1677773A1 (en) * 2003-10-14 2006-07-12 Biomira, Inc. Combination therapy for cancer
RU2666141C2 (ru) 2013-09-17 2018-09-06 Оби Фарма, Инк. Композиции углеводной вакцины для индукции иммунного ответа и их применение при лечении рака
JP2018532990A (ja) 2015-09-04 2018-11-08 オービーアイ ファーマ,インコーポレイテッド グリカンアレイおよび使用の方法
US10980894B2 (en) 2016-03-29 2021-04-20 Obi Pharma, Inc. Antibodies, pharmaceutical compositions and methods
US11041017B2 (en) 2016-03-29 2021-06-22 Obi Pharma, Inc. Antibodies, pharmaceutical compositions and methods
KR20250048399A (ko) 2016-04-22 2025-04-08 오비아이 파머 인코퍼레이티드 글로보 계열 항원을 통한 면역 활성화 또는 면역 조정에 의한 암 면역요법
WO2018022933A1 (en) 2016-07-27 2018-02-01 Obi Pharma, Inc. Immunogenic/therapeutic glycan compositions and uses thereof
EP3491026A4 (en) 2016-07-29 2020-07-29 OBI Pharma, Inc. HUMAN ANTIBODIES, PHARMACEUTICAL COMPOSITIONS AND PROCESSES
CN106645697A (zh) * 2016-11-09 2017-05-10 百奥森(江苏)食品安全科技有限公司 一种食品中玉米赤霉醇的检测试剂盒
CN106526188A (zh) * 2016-11-09 2017-03-22 百奥森(江苏)食品安全科技有限公司 一种食品中沙丁胺醇的检测试剂盒
JP2019535731A (ja) 2016-11-21 2019-12-12 オービーアイ ファーマ,インコーポレイテッド コンジュゲートさせた生物学的分子、医薬組成物及び方法
US11203645B2 (en) 2018-06-27 2021-12-21 Obi Pharma, Inc. Glycosynthase variants for glycoprotein engineering and methods of use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5407912A (en) * 1993-04-19 1995-04-18 Akzo, N.V. Method of treating bladder cancer with a keyhole limpet hemocyanin composition with enhanced anti-tumor activity
AU2247095A (en) * 1994-04-12 1995-10-30 Biomira Inc. Cellular immune response-specific antigens and uses therefor
CA2189356A1 (en) * 1994-05-02 1995-11-09 Ting Chi Wong Process for preparation of glycosides of tumor-associated carbohydrate antigens
CA2324616A1 (en) * 1998-03-25 1999-09-30 Sloan-Kettering Institute For Cancer Research Trimeric antigenic o-linked glycopeptide conjugates, methods of preparation and uses thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013532135A (ja) * 2010-06-09 2013-08-15 北京大学 シアル酸(α−(2→6))−D−ピラノース誘導体及びその合成方法と応用
JP2017532310A (ja) * 2014-09-15 2017-11-02 オービーアイ ファーマ,インコーポレイテッド 免疫原性/治療用糖コンジュゲート組成物およびその使用

Also Published As

Publication number Publication date
US20040247608A1 (en) 2004-12-09
EP1429785A4 (en) 2005-12-14
CA2454853A1 (en) 2003-02-27
CN1543350A (zh) 2004-11-03
EP1429785A1 (en) 2004-06-23
WO2003015796A1 (en) 2003-02-27

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