JP2005526015A - 結合組織修復の誘導又は促進方法 - Google Patents

結合組織修復の誘導又は促進方法 Download PDF

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Publication number
JP2005526015A
JP2005526015A JP2003560034A JP2003560034A JP2005526015A JP 2005526015 A JP2005526015 A JP 2005526015A JP 2003560034 A JP2003560034 A JP 2003560034A JP 2003560034 A JP2003560034 A JP 2003560034A JP 2005526015 A JP2005526015 A JP 2005526015A
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cell
protein
smad
variant
nucleic acid
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English (en)
Japanese (ja)
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JP2005526015A5 (https=
Inventor
ガジット、ダン
ペレド、ガディ
タルジェマン、ガディ
ホフマン、アンドレア
エーベル、ペーター
グロス、ゲルハルド
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Gbf Gesellschaft fur Biotechnologische Forschung GmbH
Yissum Research Development Co of Hebrew University of Jerusalem
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Gbf Gesellschaft fur Biotechnologische Forschung GmbH
Yissum Research Development Co of Hebrew University of Jerusalem
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Application filed by Gbf Gesellschaft fur Biotechnologische Forschung GmbH, Yissum Research Development Co of Hebrew University of Jerusalem filed Critical Gbf Gesellschaft fur Biotechnologische Forschung GmbH
Publication of JP2005526015A publication Critical patent/JP2005526015A/ja
Publication of JP2005526015A5 publication Critical patent/JP2005526015A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2003560034A 2001-12-27 2002-12-26 結合組織修復の誘導又は促進方法 Pending JP2005526015A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34237501P 2001-12-27 2001-12-27
PCT/IL2002/001041 WO2003059932A2 (en) 2001-12-27 2002-12-26 Methods of inducing or enhancing connective tissue repair

Publications (2)

Publication Number Publication Date
JP2005526015A true JP2005526015A (ja) 2005-09-02
JP2005526015A5 JP2005526015A5 (https=) 2006-02-23

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ID=23341566

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JP2003560034A Pending JP2005526015A (ja) 2001-12-27 2002-12-26 結合組織修復の誘導又は促進方法

Country Status (7)

Country Link
US (1) US20030228292A1 (https=)
EP (1) EP1467624A4 (https=)
JP (1) JP2005526015A (https=)
AU (1) AU2002366974A1 (https=)
CA (1) CA2471891A1 (https=)
IL (1) IL162736A0 (https=)
WO (1) WO2003059932A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007122823A1 (ja) * 2006-04-20 2007-11-01 Jichi Medical University ベクター産生型腫瘍標的細胞

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6755863B2 (en) * 1999-10-08 2004-06-29 Bret A. Ferree Rotator cuff repair using engineered tissues
US7435260B2 (en) 1999-08-13 2008-10-14 Ferree Bret A Use of morphogenetic proteins to treat human disc disease
WO2005077403A1 (en) * 2004-02-04 2005-08-25 Stryker Corporation Therapeutic methods using smads
US7520888B2 (en) 2006-02-14 2009-04-21 Warsaw Orthopedic, Inc. Treatment of the vertebral column
US8016859B2 (en) 2006-02-17 2011-09-13 Medtronic, Inc. Dynamic treatment system and method of use
US20100172886A1 (en) 2006-11-28 2010-07-08 University Of Southern California Method for Promoting Wound Healing
GB0820492D0 (en) 2008-11-07 2008-12-17 Sportcell Cell compositions and uses thereof
US20220039450A1 (en) * 2018-09-25 2022-02-10 Societe Des Produits Nestle S.A. Synthetic nutritional compositions tailored for infants of specific ages, and nutritional systems comprising them

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4228458A1 (de) * 1992-08-27 1994-06-01 Beiersdorf Ag Multicistronische Expressionseinheiten und deren Verwendung
JPH10117782A (ja) * 1996-10-25 1998-05-12 Otsuka Pharmaceut Co Ltd ヒトＭａｄ関連蛋白遺伝子
AU749465B2 (en) * 1997-06-13 2002-06-27 Japanese Foundation For Cancer Research Smad6 and uses thereof
EP0950414A1 (en) * 1998-04-08 1999-10-20 Boehringer Mannheim Gmbh Use of a combination of an osteoinductive protein and a dorsalizing factor for cartilage induction
US6277636B1 (en) * 2000-09-14 2001-08-21 Isis Pharmaceuticals, Inc. Antisense inhibition of MADH6 expression

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007122823A1 (ja) * 2006-04-20 2007-11-01 Jichi Medical University ベクター産生型腫瘍標的細胞
JP5283219B2 (ja) * 2006-04-20 2013-09-04 学校法人自治医科大学 ベクター産生型腫瘍標的細胞
JP2013176374A (ja) * 2006-04-20 2013-09-09 Jichi Medical Univ ベクター産生型腫瘍標的細胞

Also Published As

Publication number Publication date
WO2003059932A2 (en) 2003-07-24
EP1467624A4 (en) 2006-07-26
AU2002366974A1 (en) 2003-07-30
AU2002366974A8 (en) 2003-07-30
CA2471891A1 (en) 2003-07-24
EP1467624A2 (en) 2004-10-20
WO2003059932A3 (en) 2004-01-29
IL162736A0 (en) 2005-11-20
US20030228292A1 (en) 2003-12-11

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