JP2005526015A5 - - Google Patents
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- Publication number
- JP2005526015A5 JP2005526015A5 JP2003560034A JP2003560034A JP2005526015A5 JP 2005526015 A5 JP2005526015 A5 JP 2005526015A5 JP 2003560034 A JP2003560034 A JP 2003560034A JP 2003560034 A JP2003560034 A JP 2003560034A JP 2005526015 A5 JP2005526015 A5 JP 2005526015A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- variant
- cells
- protein
- smad protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 claims 11
- 238000000034 method Methods 0.000 claims 8
- 102000007374 Smad Proteins Human genes 0.000 claims 7
- 108010007945 Smad Proteins Proteins 0.000 claims 7
- 230000004069 differentiation Effects 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 102000049870 Smad8 Human genes 0.000 claims 3
- 108700031283 Smad8 Proteins 0.000 claims 3
- 210000004523 ligament cell Anatomy 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 230000019491 signal transduction Effects 0.000 claims 3
- 210000000130 stem cell Anatomy 0.000 claims 3
- 210000002435 tendon Anatomy 0.000 claims 3
- 210000002808 connective tissue Anatomy 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 239000000592 Artificial Cell Substances 0.000 claims 1
- 230000007547 defect Effects 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000001172 regenerating effect Effects 0.000 claims 1
- 230000000451 tissue damage Effects 0.000 claims 1
- 231100000827 tissue damage Toxicity 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34237501P | 2001-12-27 | 2001-12-27 | |
| PCT/IL2002/001041 WO2003059932A2 (en) | 2001-12-27 | 2002-12-26 | Methods of inducing or enhancing connective tissue repair |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005526015A JP2005526015A (ja) | 2005-09-02 |
| JP2005526015A5 true JP2005526015A5 (https=) | 2006-02-23 |
Family
ID=23341566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003560034A Pending JP2005526015A (ja) | 2001-12-27 | 2002-12-26 | 結合組織修復の誘導又は促進方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20030228292A1 (https=) |
| EP (1) | EP1467624A4 (https=) |
| JP (1) | JP2005526015A (https=) |
| AU (1) | AU2002366974A1 (https=) |
| CA (1) | CA2471891A1 (https=) |
| IL (1) | IL162736A0 (https=) |
| WO (1) | WO2003059932A2 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6755863B2 (en) * | 1999-10-08 | 2004-06-29 | Bret A. Ferree | Rotator cuff repair using engineered tissues |
| US7435260B2 (en) | 1999-08-13 | 2008-10-14 | Ferree Bret A | Use of morphogenetic proteins to treat human disc disease |
| WO2005077403A1 (en) * | 2004-02-04 | 2005-08-25 | Stryker Corporation | Therapeutic methods using smads |
| US7520888B2 (en) | 2006-02-14 | 2009-04-21 | Warsaw Orthopedic, Inc. | Treatment of the vertebral column |
| US8016859B2 (en) | 2006-02-17 | 2011-09-13 | Medtronic, Inc. | Dynamic treatment system and method of use |
| WO2007122823A1 (ja) * | 2006-04-20 | 2007-11-01 | Jichi Medical University | ベクター産生型腫瘍標的細胞 |
| US20100172886A1 (en) | 2006-11-28 | 2010-07-08 | University Of Southern California | Method for Promoting Wound Healing |
| GB0820492D0 (en) | 2008-11-07 | 2008-12-17 | Sportcell | Cell compositions and uses thereof |
| US20220039450A1 (en) * | 2018-09-25 | 2022-02-10 | Societe Des Produits Nestle S.A. | Synthetic nutritional compositions tailored for infants of specific ages, and nutritional systems comprising them |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4228458A1 (de) * | 1992-08-27 | 1994-06-01 | Beiersdorf Ag | Multicistronische Expressionseinheiten und deren Verwendung |
| JPH10117782A (ja) * | 1996-10-25 | 1998-05-12 | Otsuka Pharmaceut Co Ltd | ヒトＭａｄ関連蛋白遺伝子 |
| AU749465B2 (en) * | 1997-06-13 | 2002-06-27 | Japanese Foundation For Cancer Research | Smad6 and uses thereof |
| EP0950414A1 (en) * | 1998-04-08 | 1999-10-20 | Boehringer Mannheim Gmbh | Use of a combination of an osteoinductive protein and a dorsalizing factor for cartilage induction |
| US6277636B1 (en) * | 2000-09-14 | 2001-08-21 | Isis Pharmaceuticals, Inc. | Antisense inhibition of MADH6 expression |
-
2002
- 2002-12-26 US US10/328,168 patent/US20030228292A1/en not_active Abandoned
- 2002-12-26 JP JP2003560034A patent/JP2005526015A/ja active Pending
- 2002-12-26 EP EP02806380A patent/EP1467624A4/en not_active Withdrawn
- 2002-12-26 AU AU2002366974A patent/AU2002366974A1/en not_active Abandoned
- 2002-12-26 IL IL16273602A patent/IL162736A0/xx unknown
- 2002-12-26 CA CA002471891A patent/CA2471891A1/en not_active Abandoned
- 2002-12-26 WO PCT/IL2002/001041 patent/WO2003059932A2/en not_active Ceased
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