JP2005518403A5 - - Google Patents
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- Publication number
- JP2005518403A5 JP2005518403A5 JP2003559448A JP2003559448A JP2005518403A5 JP 2005518403 A5 JP2005518403 A5 JP 2005518403A5 JP 2003559448 A JP2003559448 A JP 2003559448A JP 2003559448 A JP2003559448 A JP 2003559448A JP 2005518403 A5 JP2005518403 A5 JP 2005518403A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- administration
- mammal
- cyclohexenone
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 241000124008 Mammalia Species 0.000 claims 5
- FVIJFRPQQNCETD-UHFFFAOYSA-N 3-(5-methoxyheptyl)cyclohex-2-en-1-one Chemical compound CCC(OC)CCCCC1=CC(=O)CCC1 FVIJFRPQQNCETD-UHFFFAOYSA-N 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 206010000496 Acne Diseases 0.000 claims 1
- 206010015037 Epilepsy Diseases 0.000 claims 1
- 208000002260 Keloid Diseases 0.000 claims 1
- 210000001117 Keloid Anatomy 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 102000001307 androgen receptors Human genes 0.000 claims 1
- 108010080146 androgen receptors Proteins 0.000 claims 1
- 230000000903 blocking Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 230000000699 topical Effects 0.000 claims 1
Claims (10)
- 以下の式を有する化合物：
- ＲがＣＨ３である、請求項１に記載の化合物。
- 哺乳動物においてアンドロゲンレセプター部位をブロックするための組成物であって、有効用量の３−（５−メトキシヘプチル）−２−シクロヘキセノンを含む、組成物。
- 前記組成物が局所投与のために適合されている、請求項３に記載の組成物。
- 前記組成物が経口投与のために適合されている、請求項３に記載の組成物。
- 前記組成物が内部投与のために適合されている、請求項３に記載の組成物。
- 前記組成物が挫瘡に罹患した哺乳動物への投与のために適合されている、請求項３に記載の組成物。
- 前記組成物がケロイドに罹患した哺乳動物への投与のために適合されている、請求項３に記載の組成物。
- 前記組成物が雄性パターン禿に冒された哺乳動物への投与のために適合されている、請求項３に記載の組成物。
- ３−（５−メトキシヘプチル）−２−シクロヘキセノンを含む、哺乳動物に投与するための組成物。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34654502P | 2002-01-09 | 2002-01-09 | |
| PCT/US2003/000534 WO2003059283A2 (en) | 2002-01-09 | 2003-01-09 | Compounds for blocking androgen receptors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005518403A JP2005518403A (ja) | 2005-06-23 |
| JP2005518403A5 true JP2005518403A5 (ja) | 2006-03-02 |
Family
ID=23359898
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003559448A Pending JP2005518403A (ja) | 2002-01-09 | 2003-01-09 | アンドロゲンレセプターをブロックする化合物 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6768026B2 (ja) |
| EP (1) | EP1474122A4 (ja) |
| JP (1) | JP2005518403A (ja) |
| KR (1) | KR20040086262A (ja) |
| CN (1) | CN1273121C (ja) |
| AU (1) | AU2003235672A1 (ja) |
| CA (1) | CA2473908A1 (ja) |
| IL (1) | IL162849A0 (ja) |
| WO (1) | WO2003059283A2 (ja) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20040086262A (ko) * | 2002-01-09 | 2004-10-08 | 트라이던트 사이언스 엘엘씨 | 안드로겐 수용체 차단 화합물 |
| US20060263452A1 (en) * | 2005-05-17 | 2006-11-23 | Alwyn Dowell | Topical composition containing essential oils |
| US20070048246A1 (en) * | 2005-09-01 | 2007-03-01 | Biophysica Research, Inc. | Novel skin care compositions |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5135849A (en) * | 1986-04-17 | 1992-08-04 | Trustees Of Tufts College | In-vitro methods for identifying compositions which are agonists and antagonists of androgens |
| US5808139A (en) * | 1992-04-21 | 1998-09-15 | Ligand Pharmaceuticals Incorporated | Non-steroid progesterone receptor agonist and antagonist and compounds and methods |
| US5264619B1 (en) * | 1993-01-15 | 1996-05-14 | Cosmos Pharm Corp | Anti-androgenic cyclo and bicyclo alkenes |
| US6228893B1 (en) * | 1997-08-13 | 2001-05-08 | Meiji Milk Products Co., Ltd. | Cyclohexenone long-chain alcohol and medicament containing same |
| US6566372B1 (en) * | 1999-08-27 | 2003-05-20 | Ligand Pharmaceuticals Incorporated | Bicyclic androgen and progesterone receptor modulator compounds and methods |
| KR20040086262A (ko) * | 2002-01-09 | 2004-10-08 | 트라이던트 사이언스 엘엘씨 | 안드로겐 수용체 차단 화합물 |
-
2003
- 2003-01-09 KR KR10-2004-7010712A patent/KR20040086262A/ko not_active Application Discontinuation
- 2003-01-09 CN CNB038020432A patent/CN1273121C/zh not_active Expired - Fee Related
- 2003-01-09 CA CA002473908A patent/CA2473908A1/en not_active Abandoned
- 2003-01-09 US US10/338,889 patent/US6768026B2/en not_active Expired - Fee Related
- 2003-01-09 WO PCT/US2003/000534 patent/WO2003059283A2/en not_active Application Discontinuation
- 2003-01-09 IL IL16284903A patent/IL162849A0/xx unknown
- 2003-01-09 AU AU2003235672A patent/AU2003235672A1/en not_active Abandoned
- 2003-01-09 JP JP2003559448A patent/JP2005518403A/ja active Pending
- 2003-01-09 EP EP03729598A patent/EP1474122A4/en not_active Withdrawn
-
2004
- 2004-07-12 US US10/888,544 patent/US7211604B2/en not_active Expired - Fee Related