JP2005517452A - 短干渉核酸（ｓｉＮＡ）を用いるＢＣＬ２遺伝子発現のＲＮＡ干渉媒介性阻害 - Google Patents

短干渉核酸（ｓｉＮＡ）を用いるＢＣＬ２遺伝子発現のＲＮＡ干渉媒介性阻害 Download PDF

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JP2005517452A
JP2005517452A JP2003569860A JP2003569860A JP2005517452A JP 2005517452 A JP2005517452 A JP 2005517452A JP 2003569860 A JP2003569860 A JP 2003569860A JP 2003569860 A JP2003569860 A JP 2003569860A JP 2005517452 A JP2005517452 A JP 2005517452A
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sina
nucleotides
sina molecule
sequence
nucleotide
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JP2005517452A5 (fr
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マクスウィゲン，ジェームズ
ベージェルマン，レオニド
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Sirna Therapeutics Inc
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JP2003569860A 2002-02-20 2003-02-18 短干渉核酸（ｓｉＮＡ）を用いるＢＣＬ２遺伝子発現のＲＮＡ干渉媒介性阻害 Pending JP2005517452A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US35858002P 2002-02-20 2002-02-20
US36312402P 2002-03-11 2002-03-11
US38678202P 2002-06-06 2002-06-06
US39690502P 2002-07-18 2002-07-18
US40678402P 2002-08-29 2002-08-29
US40837802P 2002-09-05 2002-09-05
US40929302P 2002-09-09 2002-09-09
US44012903P 2003-01-15 2003-01-15
PCT/US2003/004908 WO2003070969A2 (fr) 2002-02-20 2003-02-18 Inhibition de l'expression du gene bcl2 induite par interference arn au moyen de petits acides nucleiques interferents (sina)

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JP2005517452A true JP2005517452A (ja) 2005-06-16
JP2005517452A5 JP2005517452A5 (fr) 2006-03-30

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JP2003569860A Pending JP2005517452A (ja) 2002-02-20 2003-02-18 短干渉核酸（ｓｉＮＡ）を用いるＢＣＬ２遺伝子発現のＲＮＡ干渉媒介性阻害

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EP (1) EP1442143A4 (fr)
JP (1) JP2005517452A (fr)
AU (1) AU2003213119A1 (fr)
CA (1) CA2463595A1 (fr)
WO (1) WO2003070969A2 (fr)

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JP2009507918A (ja) * 2005-09-12 2009-02-26 ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション Ｂｃｌ２関連癌の診断及び療法のための組成物及び方法
JP2010503414A (ja) * 2006-09-15 2010-02-04 エンゾン ファーマスーティカルズ インコーポレイテッド 正に荷電した部分を含有するポリマー複合体
WO2010021389A1 (fr) * 2008-08-21 2010-02-25 協和発酵キリン株式会社 Acide nucléique capable d'inhiber l'expression de la protéine bcl-2
JP2010510810A (ja) * 2006-11-27 2010-04-08 エンゾン ファーマスーティカルズ インコーポレイテッド ポリマー低分子干渉ｒｎａ複合体
WO2013133221A1 (fr) * 2012-03-04 2013-09-12 株式会社ボナック INHIBITEUR DE micro-ARN
US8859202B2 (en) 2012-01-20 2014-10-14 The Ohio State University Breast cancer biomarker signatures for invasiveness and prognosis
US8865885B2 (en) 2006-03-20 2014-10-21 The Ohio State University Research Foundation MicroRNA fingerprints during human megakaryocytopoiesis
US8916533B2 (en) 2009-11-23 2014-12-23 The Ohio State University Materials and methods useful for affecting tumor cell growth, migration and invasion
US8946187B2 (en) 2010-11-12 2015-02-03 The Ohio State University Materials and methods related to microRNA-21, mismatch repair, and colorectal cancer
US9017940B2 (en) 2006-01-05 2015-04-28 The Ohio State University Methods for diagnosing colon cancer using MicroRNA signatures
US9085804B2 (en) 2007-08-03 2015-07-21 The Ohio State University Research Foundation Ultraconserved regions encoding ncRNAs
US9249468B2 (en) 2011-10-14 2016-02-02 The Ohio State University Methods and materials related to ovarian cancer
US9481885B2 (en) 2011-12-13 2016-11-01 Ohio State Innovation Foundation Methods and compositions related to miR-21 and miR-29a, exosome inhibition, and cancer metastasis
US10758619B2 (en) 2010-11-15 2020-09-01 The Ohio State University Controlled release mucoadhesive systems
WO2020196736A1 (fr) * 2019-03-28 2020-10-01 日東電工株式会社 Molécule d'arni

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US7745418B2 (en) 2001-10-12 2010-06-29 Alnylam Pharmaceuticals, Inc. Compositions and methods for inhibiting viral replication
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CN103140582A (zh) 2010-08-24 2013-06-05 默沙东公司 含有内部非核酸间隔子的单链RNAi试剂
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KR20150087270A (ko) * 2012-11-05 2015-07-29 프로나이 테라퓨틱스, 인코포레이티드 Bcl2 발현 조절에 의한 암치료용 바이오마커 이용 방법
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