JP2005516114A - 被分析物の脱離／イオン化に有用なエネルギー吸収部分を有するモノマーおよびポリマー - Google Patents

被分析物の脱離／イオン化に有用なエネルギー吸収部分を有するモノマーおよびポリマー Download PDF

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JP2005516114A
JP2005516114A JP2003564190A JP2003564190A JP2005516114A JP 2005516114 A JP2005516114 A JP 2005516114A JP 2003564190 A JP2003564190 A JP 2003564190A JP 2003564190 A JP2003564190 A JP 2003564190A JP 2005516114 A JP2005516114 A JP 2005516114A
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polymer
moiety
photoreactive
monomer
functional moiety
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JP2003564190A
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JP2005516114A5 (https=
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ナオタカ キタガワ，
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サイファージェン バイオシステムズ， インコーポレイテッド
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Priority claimed from US10/327,511 external-priority patent/US20030207462A1/en
Application filed by サイファージェン バイオシステムズ， インコーポレイテッド filed Critical サイファージェン バイオシステムズ， インコーポレイテッド
Publication of JP2005516114A publication Critical patent/JP2005516114A/ja
Publication of JP2005516114A5 publication Critical patent/JP2005516114A5/ja
Pending legal-status Critical Current

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    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0409—Sample holders or containers
    • H01J49/0418—Sample holders or containers for laser desorption, e.g. matrix-assisted laser desorption/ionisation [MALDI] plates or surface enhanced laser desorption/ionisation [SELDI] plates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/41—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by carboxyl groups, other than cyano groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
    • C07C69/533—Monocarboxylic acid esters having only one carbon-to-carbon double bond
    • C07C69/54—Acrylic acid esters; Methacrylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/34—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate
    • C08F220/36—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate containing oxygen in addition to the carboxy oxygen, e.g. 2-N-morpholinoethyl (meth)acrylate or 2-isocyanatoethyl (meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F246/00—Copolymers in which the nature of only the monomers in minority is defined
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
JP2003564190A 2002-01-25 2002-12-20 被分析物の脱離／イオン化に有用なエネルギー吸収部分を有するモノマーおよびポリマー Pending JP2005516114A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US35197102P 2002-01-25 2002-01-25
US40825502P 2002-09-04 2002-09-04
US10/327,511 US20030207462A1 (en) 2002-01-25 2002-12-19 Monomers and polymers having energy absorbing moieties of use in desorption/ionization of analytes
US10/326,219 US7276381B2 (en) 2002-01-25 2002-12-20 Monomers and polymers having energy absorbing moieties of use in desorption/ionization of analytes
PCT/US2002/041197 WO2003064594A2 (en) 2002-01-25 2002-12-20 Monomers and polymers having energy absorbing moieties of use in desorption/ionization of analytes

Publications (2)

Publication Number Publication Date
JP2005516114A true JP2005516114A (ja) 2005-06-02
JP2005516114A5 JP2005516114A5 (https=) 2006-01-05

Family

ID=27671072

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003564190A Pending JP2005516114A (ja) 2002-01-25 2002-12-20 被分析物の脱離／イオン化に有用なエネルギー吸収部分を有するモノマーおよびポリマー

Country Status (4)

Country Link
US (1) US7276381B2 (https=)
EP (1) EP1481244A4 (https=)
JP (1) JP2005516114A (https=)
WO (1) WO2003064594A2 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010216945A (ja) * 2009-03-16 2010-09-30 Sumitomo Electric Ind Ltd 分析法
JP2011207942A (ja) * 2010-03-29 2011-10-20 Fujifilm Corp 化合物、重合性組成物、高分子、及びフィルム
WO2019078145A1 (ja) * 2017-10-20 2019-04-25 Jsr株式会社 質量分析用試料を調製するための材料
JP2022142520A (ja) * 2021-03-16 2022-09-30 株式会社豊田中央研究所 有機シリカ基板、及びそれを用いたレーザー脱離／イオン化質量分析方法

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1578527A1 (en) 2002-09-13 2005-09-28 Ciphergen Biosystems, Inc. Preparation and use of mixed mode solid substrates for chromatography adsorbents and biochip arrays
US7045366B2 (en) 2003-09-12 2006-05-16 Ciphergen Biosystems, Inc. Photocrosslinked hydrogel blend surface coatings
US6977370B1 (en) 2003-04-07 2005-12-20 Ciphergen Biosystems, Inc. Off-resonance mid-IR laser desorption ionization
WO2004094460A2 (en) 2003-04-17 2004-11-04 Ciphergen Biosystems, Inc. Polypeptides related to natriuretic peptides and methods of their identification and use
ES2727785T3 (es) 2003-05-19 2019-10-18 Toray Industries Soporte que tiene una sustancia de unión selectiva fijada al mismo
JP4796967B2 (ja) 2003-11-07 2011-10-19 ヴァーミリオン インコーポレイテッド アルツハイマー病のためのバイオマーカー
WO2005073711A2 (en) 2004-01-20 2005-08-11 Pall Corporation Chromatographic material for the absorption of proteins at physiological ionic strength
CN1942761A (zh) * 2004-04-21 2007-04-04 东丽株式会社 芯片实验室用基板
EP1802961A4 (en) * 2004-09-29 2007-11-14 Bio Rad Laboratories Host-guest enery-absorbing complex
DE102004053458A1 (de) * 2004-11-05 2006-05-11 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Strukturierte polymere Träger für die Massenspektrometrie und Verfahren zu deren Herstellung
US20060254916A1 (en) * 2005-05-16 2006-11-16 Hernandez Juan J Methods of forming microfluidic devices and uses thereof
US20060261267A1 (en) * 2005-05-20 2006-11-23 Agency For Science, Technology And Research Composite MALDI matrix material and methods of using it and kits thereof in MALDI
EP2993474B1 (en) 2005-06-24 2019-06-12 Vermillion, Inc. Biomarkers for ovarian cancer: beta-2 microglobulin
JP2007171003A (ja) 2005-12-22 2007-07-05 Fujifilm Corp 質量分析用基板並びに分析方法および装置
EP1996949A4 (en) 2006-03-11 2010-01-20 Univ Leland Stanford Junior BETA-2 MICROGLOBULIN AS A BIOMARKER FOR PERIPHERAL ARTERY DISEASE
US20100176287A1 (en) * 2006-11-23 2010-07-15 Koninklijke Philips Electronics N.V. Device for separation and maldi analysis of an analyte in a sample
US7999221B2 (en) * 2008-06-02 2011-08-16 Bio-Rad Laboratories, Inc. Mass spectrometric detection of material transferred to a surface
EP2452200A1 (en) * 2009-07-09 2012-05-16 Koninklijke Philips Electronics N.V. Surface coating for laser desorption ionization mass spectrometry of molecules
EP2805167B1 (en) 2012-01-20 2020-04-22 Adelaide Research & Innovation Pty Ltd Biomarkers for gastric cancer and uses thereof
AU2013202668B2 (en) 2012-12-24 2014-12-18 Adelaide Research & Innovation Pty Ltd Inhibition of cancer growth and metastasis
US10262850B2 (en) * 2016-12-19 2019-04-16 Perkinelmer Health Sciences Canada, Inc. Inorganic and organic mass spectrometry systems and methods of using them
US11866779B2 (en) 2018-02-28 2024-01-09 Northeastern University Jettison-MS for nucleic acid species
US12116637B2 (en) 2020-07-24 2024-10-15 The Regents Of The University Of Michigan Compositions and methods for detecting and treating high grade subtypes of uterine cancer
JP2024502618A (ja) 2021-01-08 2024-01-22 セラノーム， インコーポレイテッド 生体試料を分析するためのデバイスおよび方法
US12576400B2 (en) 2021-01-08 2026-03-17 Cellanome, Inc. Methods for incubating and analyzing a cell in a compartment of a fluidic device
WO2022150659A1 (en) * 2021-01-08 2022-07-14 Cellanome, Inc. Devices and methods for analyzing biological samples
CN113325064A (zh) * 2021-05-28 2021-08-31 华南农业大学 一种大气压化学电离质谱鉴定魅力峰乳化剂组成成分的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3070442A (en) * 1958-07-18 1962-12-25 Du Pont Process for producing colored polymeric relief images and elements therefor
US3748133A (en) * 1972-03-24 1973-07-24 Eastman Kodak Co Photopolymerizable compositions and elements and uses thereof
GB1425423A (en) * 1972-04-26 1976-02-18 Eastman Kodak Co Photopolymerisable compositions
US5002582A (en) * 1982-09-29 1991-03-26 Bio-Metric Systems, Inc. Preparation of polymeric surfaces via covalently attaching polymers
US5512329A (en) * 1982-09-29 1996-04-30 Bsi Corporation Substrate surface preparation
JPS5968731A (ja) * 1982-10-12 1984-04-18 Fuji Photo Film Co Ltd ハロゲン化銀写真感光材料
JPH0471896A (ja) 1990-07-12 1992-03-06 Fuji Photo Film Co Ltd 感熱記録材料
ATE242485T1 (de) * 1993-05-28 2003-06-15 Baylor College Medicine Verfahren und massenspektrometer zur desorption und ionisierung von analyten
EP0764264A2 (en) * 1993-11-12 1997-03-26 Waters Corporation Enhanced resolution maldi tof-ms sample surface
NO952329D0 (no) 1995-06-13 1995-06-13 Jotun As Polymerer for grohemmende maling og fremgangsmåte for fremstilling derav
DE19628178C1 (de) * 1996-07-12 1997-09-18 Bruker Franzen Analytik Gmbh Verfahren zum Beladen von Probenträgern für Massenspektrometer
JPH11165052A (ja) 1997-12-04 1999-06-22 Toray Ind Inc 半透膜およびその製造方法

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010216945A (ja) * 2009-03-16 2010-09-30 Sumitomo Electric Ind Ltd 分析法
JP2011207942A (ja) * 2010-03-29 2011-10-20 Fujifilm Corp 化合物、重合性組成物、高分子、及びフィルム
WO2019078145A1 (ja) * 2017-10-20 2019-04-25 Jsr株式会社 質量分析用試料を調製するための材料
JPWO2019078145A1 (ja) * 2017-10-20 2020-11-19 Jsr株式会社 質量分析用試料を調製するための材料
JP7382600B2 (ja) 2017-10-20 2023-11-17 Jsr株式会社 質量分析用試料を調製するための材料
JP2022142520A (ja) * 2021-03-16 2022-09-30 株式会社豊田中央研究所 有機シリカ基板、及びそれを用いたレーザー脱離／イオン化質量分析方法
JP7421170B2 (ja) 2021-03-16 2024-01-24 株式会社豊田中央研究所 有機シリカ基板、及びそれを用いたレーザー脱離／イオン化質量分析方法

Also Published As

Publication number Publication date
WO2003064594A3 (en) 2004-07-22
WO2003064594A2 (en) 2003-08-07
US20030207460A1 (en) 2003-11-06
US7276381B2 (en) 2007-10-02
EP1481244A2 (en) 2004-12-01
EP1481244A4 (en) 2008-07-02

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