JP2005511002A - 骨量変調のトランスジェニック動物モデル - Google Patents

骨量変調のトランスジェニック動物モデル Download PDF

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JP2005511002A
JP2005511002A JP2002589632A JP2002589632A JP2005511002A JP 2005511002 A JP2005511002 A JP 2005511002A JP 2002589632 A JP2002589632 A JP 2002589632A JP 2002589632 A JP2002589632 A JP 2002589632A JP 2005511002 A JP2005511002 A JP 2005511002A
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gene
bone
hbm
lrp5
mouse
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Japanese (ja)
Inventor
バビィ，フィリップ
ベックス，フレデリック・ジェイムズ，ザ・サード
ボーディン，ピーター・ヴァン・ネスト
アスキュー，ロジャー・ジー
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Wyeth LLC
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Wyeth LLC
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
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    • A01K2227/10—Mammal
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    • A01K2267/035—Animal model for multifactorial diseases
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  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Animal Husbandry (AREA)
  • Diabetes (AREA)
  • General Engineering & Computer Science (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Biomedical Technology (AREA)
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  • Wood Science & Technology (AREA)
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JP2002589632A 2001-05-11 2002-05-13 骨量変調のトランスジェニック動物モデル Withdrawn JP2005511002A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US29007101P 2001-05-11 2001-05-11
US29131101P 2001-05-17 2001-05-17
US35305802P 2002-02-01 2002-02-01
US36129302P 2002-03-04 2002-03-04
PCT/US2002/014876 WO2002092764A2 (en) 2001-05-11 2002-05-13 Transgenic animal model of bone mass modulation

Publications (1)

Publication Number Publication Date
JP2005511002A true JP2005511002A (ja) 2005-04-28

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Family Applications (3)

Application Number Title Priority Date Filing Date
JP2002589632A Withdrawn JP2005511002A (ja) 2001-05-11 2002-05-13 骨量変調のトランスジェニック動物モデル
JP2002588919A Withdrawn JP2004537289A (ja) 2001-05-11 2002-05-13 骨量および脂質レベルを調整するｈｂｍ変異型
JP2010146427A Pending JP2011004744A (ja) 2001-05-11 2010-06-28 骨量および脂質レベルを調整するｈｂｍ変異型

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Application Number Title Priority Date Filing Date
JP2002588919A Withdrawn JP2004537289A (ja) 2001-05-11 2002-05-13 骨量および脂質レベルを調整するｈｂｍ変異型
JP2010146427A Pending JP2011004744A (ja) 2001-05-11 2010-06-28 骨量および脂質レベルを調整するｈｂｍ変異型

Country Status (7)

Country Link
US (2) US7416849B2 (https=)
EP (2) EP1483288A4 (https=)
JP (3) JP2005511002A (https=)
AU (2) AU2002308681A1 (https=)
BR (2) BR0209563A (https=)
CA (2) CA2446821A1 (https=)
WO (2) WO2002092000A2 (https=)

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