JP2005508320A5 - - Google Patents

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Publication number
JP2005508320A5
JP2005508320A5 JP2003528805A JP2003528805A JP2005508320A5 JP 2005508320 A5 JP2005508320 A5 JP 2005508320A5 JP 2003528805 A JP2003528805 A JP 2003528805A JP 2003528805 A JP2003528805 A JP 2003528805A JP 2005508320 A5 JP2005508320 A5 JP 2005508320A5
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JP
Japan
Prior art keywords
substituted
group
formula
alkyl
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2003528805A
Other languages
English (en)
Japanese (ja)
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JP2005508320A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2002/029581 external-priority patent/WO2003024958A2/en
Publication of JP2005508320A publication Critical patent/JP2005508320A/ja
Publication of JP2005508320A5 publication Critical patent/JP2005508320A5/ja
Withdrawn legal-status Critical Current

Links

JP2003528805A 2001-09-18 2002-09-18 1,5−ジアリール−3−置換ピラゾールの調製方法 Withdrawn JP2005508320A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32347901P 2001-09-18 2001-09-18
PCT/US2002/029581 WO2003024958A2 (en) 2001-09-18 2002-09-18 Processes for the preparation of 1,5-diaryl-3-substituted-pyrazoles

Publications (2)

Publication Number Publication Date
JP2005508320A JP2005508320A (ja) 2005-03-31
JP2005508320A5 true JP2005508320A5 (enExample) 2005-12-15

Family

ID=23259369

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003528805A Withdrawn JP2005508320A (ja) 2001-09-18 2002-09-18 1,5−ジアリール−3−置換ピラゾールの調製方法

Country Status (5)

Country Link
US (2) US6906196B2 (enExample)
EP (1) EP1436285A4 (enExample)
JP (1) JP2005508320A (enExample)
NZ (1) NZ532346A (enExample)
WO (1) WO2003024958A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1436285A4 (en) * 2001-09-18 2004-12-15 Onconova Therapeutics Inc METHOD FOR PRODUCING 1,5-DIARYL-3-SUBSTITUTED PYRAZOLES
AU2002337843A1 (en) * 2001-10-12 2003-04-22 Onconova Therapeutics, Inc. Processes for the preparation of substituted isoxazoles and 2-isoxazolines
WO2003086287A2 (en) * 2002-04-08 2003-10-23 The Ohio State University Research Foundation Compounds and methods for inducing apoptosis in proliferating cells
UA79804C2 (en) 2002-07-03 2007-07-25 Janssen Pharmaceutica Nv Cck-1 receptor modulators
WO2005005393A2 (en) * 2003-07-02 2005-01-20 Janssen Pharmaceutica N.V. Cck-1 receptor modulators
JP4269902B2 (ja) * 2003-08-27 2009-05-27 住友化学株式会社 芳香族不飽和化合物の製造方法
CN103992274A (zh) * 2014-04-18 2014-08-20 南京安美科技有限公司 合成选择性非甾体抗炎镇痛药Celebrex(塞来昔布)的方法
CN107573266A (zh) * 2017-09-19 2018-01-12 黑龙江鑫创生物科技开发有限公司 一种对肼基苯磺酰胺盐酸盐的合成方法
CN111217753A (zh) * 2020-04-02 2020-06-02 农永强 一种塞来昔布的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2974141A (en) * 1958-12-17 1961-03-07 Gen Aniline & Film Corp P-(2-pyrazolin-1-yl) styryl dyes
US5013850A (en) * 1990-03-30 1991-05-07 Allergan, Inc. 4-ethyl and 4-ethenyl-5-hydroxy-2(5H)-furanones substituted on alpha carbon of the ethyl or ethenyl side chain with a long chain alkyl group and on the beta carbon with a polar group, as anti-inflammatory agents
US5466823A (en) * 1993-11-30 1995-11-14 G.D. Searle & Co. Substituted pyrazolyl benzenesulfonamides
US5675017A (en) * 1995-06-07 1997-10-07 Monsanto Company Herbicidal substituted 3-aryl-pyrazoles
GEP20032998B (en) * 1996-04-12 2003-06-25 Searle & Co Substituted Benzenesulfonamide Derivatives as Prodrugs of Cox-2 Inhibitors
DE19621687A1 (de) * 1996-05-30 1997-12-04 Bayer Ag Verfahren zur Herstellung von substituierten Arylpyrazolen
US6373519B1 (en) * 1998-10-15 2002-04-16 Philip Morris Incorporated System and method for visually inspecting a cigarette packaging process
KR100796851B1 (ko) * 1999-06-16 2008-01-22 템플 유니버시티-오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 사이클록시게나아제-2의 억제제로서 1-(4-설파밀아릴)-3-치환형-5-아릴-2-피라졸린
TR200001872A3 (tr) 2000-06-26 2002-01-21 Fako Ilaclari A.S 4-[5-(4-Metilfenil-3-(triflorometil)-1H-pirazol-1-il] benzensulfonamit' in yeni kristal biçimi "Biçim I" ve bu ürünün üretilmesine iliskin yöntem.
US6579988B2 (en) * 2001-09-18 2003-06-17 Onconova Therapeutics, Inc. Processes for the preparation of 1,5-diarylpyrazoles
EP1436285A4 (en) * 2001-09-18 2004-12-15 Onconova Therapeutics Inc METHOD FOR PRODUCING 1,5-DIARYL-3-SUBSTITUTED PYRAZOLES

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