ATE361748T1 - 1-(4-sulfamylphenyl)-3-trifluormethyl-5-aryl-2- pyrazoline als cyclooxygenase-2 inhibitoren - Google Patents

1-(4-sulfamylphenyl)-3-trifluormethyl-5-aryl-2- pyrazoline als cyclooxygenase-2 inhibitoren

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Publication number
ATE361748T1
ATE361748T1 AT00939946T AT00939946T ATE361748T1 AT E361748 T1 ATE361748 T1 AT E361748T1 AT 00939946 T AT00939946 T AT 00939946T AT 00939946 T AT00939946 T AT 00939946T AT E361748 T1 ATE361748 T1 AT E361748T1
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AT
Austria
Prior art keywords
sub
cyclooxygenase
group
inhibitors
aryl
Prior art date
Application number
AT00939946T
Other languages
English (en)
Inventor
E Reddy
M Reddy
Original Assignee
Univ Temple
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Publication date
Application filed by Univ Temple filed Critical Univ Temple
Application granted granted Critical
Publication of ATE361748T1 publication Critical patent/ATE361748T1/de

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P11/06—Antiasthmatics
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    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
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    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Transplantation (AREA)
  • Emergency Medicine (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT00939946T 1999-06-16 2000-06-16 1-(4-sulfamylphenyl)-3-trifluormethyl-5-aryl-2- pyrazoline als cyclooxygenase-2 inhibitoren ATE361748T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13941699P 1999-06-16 1999-06-16

Publications (1)

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ATE361748T1 true ATE361748T1 (de) 2007-06-15

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AT00939946T ATE361748T1 (de) 1999-06-16 2000-06-16 1-(4-sulfamylphenyl)-3-trifluormethyl-5-aryl-2- pyrazoline als cyclooxygenase-2 inhibitoren

Country Status (11)

Country Link
US (2) US6376519B1 (de)
EP (1) EP1191931B1 (de)
JP (1) JP2003501464A (de)
KR (1) KR100796851B1 (de)
AT (1) ATE361748T1 (de)
AU (1) AU771668C (de)
CA (1) CA2377153A1 (de)
DE (1) DE60034785D1 (de)
IL (2) IL146851A0 (de)
NZ (1) NZ516553A (de)
WO (1) WO2000076503A1 (de)

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JP2003501464A (ja) 2003-01-14
AU5495100A (en) 2001-01-02
CA2377153A1 (en) 2000-12-21
EP1191931A1 (de) 2002-04-03
AU771668B2 (en) 2004-04-01
USRE39681E1 (en) 2007-06-05
KR100796851B1 (ko) 2008-01-22
EP1191931A4 (de) 2002-11-27
NZ516553A (en) 2004-01-30
KR20020015350A (ko) 2002-02-27
IL146851A (en) 2008-03-20
IL146851A0 (en) 2002-07-25
US6376519B1 (en) 2002-04-23
WO2000076503A1 (en) 2000-12-21
AU771668C (en) 2005-08-11
EP1191931B1 (de) 2007-05-09
DE60034785D1 (en) 2007-06-21

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