MX9709646A - Derivados de bencimidazol como inhibidores de proliferacion de celulas de musculo liso. - Google Patents
Derivados de bencimidazol como inhibidores de proliferacion de celulas de musculo liso.Info
- Publication number
- MX9709646A MX9709646A MX9709646A MX9709646A MX9709646A MX 9709646 A MX9709646 A MX 9709646A MX 9709646 A MX9709646 A MX 9709646A MX 9709646 A MX9709646 A MX 9709646A MX 9709646 A MX9709646 A MX 9709646A
- Authority
- MX
- Mexico
- Prior art keywords
- inhibitors
- cell proliferation
- smooth muscle
- muscle cell
- benzimidazole derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/12—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/08—Radicals containing only hydrogen and carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
Abstract
En la presente se describen compuestos y sales farmacéuticamente aceptables de compuestos de formula (I) o (II), en las qur R es alquilo, fenilo o fenilo sustituido; R2 es hidrogeno, hologeno, alcoxi o alquilo; R1 es hidrogeno, alquilo, arilo, arilalquilo o bencilo sustituido; los cuales son utiles como inhibidores de proliferacion de células de musculo liso.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08468482 | 1995-06-06 | ||
US08/468,482 US6288100B1 (en) | 1995-06-06 | 1995-06-06 | Benzimidazole derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
MX9709646A true MX9709646A (es) | 1998-07-31 |
MXPA97009646A MXPA97009646A (es) | 1998-11-09 |
Family
ID=
Also Published As
Publication number | Publication date |
---|---|
AR002748A1 (es) | 1998-04-29 |
ZA964692B (en) | 1997-12-05 |
EP0830343A1 (en) | 1998-03-25 |
IL118384A0 (en) | 1996-09-12 |
CN1192205A (zh) | 1998-09-02 |
WO1996039390A1 (en) | 1996-12-12 |
AU5967396A (en) | 1996-12-24 |
BR9609365A (pt) | 1999-05-18 |
US6288100B1 (en) | 2001-09-11 |
NZ309490A (en) | 1999-09-29 |
CA2223393A1 (en) | 1996-12-12 |
JPH11506749A (ja) | 1999-06-15 |
AU713043B2 (en) | 1999-11-25 |
KR19990022372A (ko) | 1999-03-25 |
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