JP2005508131A - 線維芽細胞成長因子−23分子およびその使用 - Google Patents
線維芽細胞成長因子−23分子およびその使用 Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Toxicology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18244200P | 2000-02-15 | 2000-02-15 | |
US19890300P | 2000-04-20 | 2000-04-20 | |
US74858101A | 2001-02-15 | 2001-02-15 | |
PCT/US2001/004778 WO2001061007A2 (fr) | 2000-02-15 | 2001-02-15 | Molecules du facteur 23 de croissance de fibroblastes et procedes d'utilisation correspondants |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006164101A Division JP2006238894A (ja) | 2000-02-15 | 2006-06-13 | 線維芽細胞成長因子−23分子およびその使用 |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2005508131A true JP2005508131A (ja) | 2005-03-31 |
Family
ID=27391551
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2001560377A Withdrawn JP2005508131A (ja) | 2000-02-15 | 2001-02-15 | 線維芽細胞成長因子−23分子およびその使用 |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1257645A2 (fr) |
JP (1) | JP2005508131A (fr) |
AU (1) | AU3976701A (fr) |
CA (1) | CA2398603A1 (fr) |
MX (1) | MXPA02007619A (fr) |
WO (1) | WO2001061007A2 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011519043A (ja) * | 2008-04-29 | 2011-06-30 | ノバルティス アーゲー | 線維芽細胞増殖因子受容体のキナーゼ活性のモジュレーションをモニタリングする方法、および該方法の使用 |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001066596A2 (fr) * | 2000-03-08 | 2001-09-13 | Chiron Corporation | Gene humain fgf-23 et produits d'expression genique |
US20020082205A1 (en) * | 2000-03-08 | 2002-06-27 | Nobuyuki Itoh | Human FGF-23 gene and gene expression products |
AU7332301A (en) | 2000-07-19 | 2002-02-05 | Advanced Res & Tech Inst | Novel fibroblast growth factor (FGF23) and methods for use |
ATE469217T1 (de) | 2000-08-11 | 2010-06-15 | Kyowa Hakko Kirin Co Ltd | Den phosphorsäure-metabolismus, den kalzium- metabolismus, verkalkung und den vitamin d- metabolismus kontrollierende polypeptide sowie für diese kodierende dna-moleküle |
EP1381683A2 (fr) * | 2001-04-26 | 2004-01-21 | Geneprot, Inc. | Compositions associees au facteur de croissance de fibroblastes humain |
KR101016476B1 (ko) * | 2001-12-28 | 2011-02-24 | 교와 핫꼬 기린 가부시키가이샤 | 섬유아세포 증식 인자-23에 대한 항체 |
US7094551B2 (en) | 2002-09-17 | 2006-08-22 | Zahradnik Richard J | Immunoassays, assay methods, antibodies and method of creating antibodies for detecting FGF-23 |
US7883705B2 (en) | 2007-02-14 | 2011-02-08 | Kyowa Hakko Kirin Co., Ltd. | Anti FGF23 antibody and a pharmaceutical composition comprising the same |
MY163674A (en) | 2011-07-01 | 2017-10-13 | Ngm Biopharmaceuticals Inc | Compositions, uses and method for treatment of metabolic disorders and diseases |
AU2013352363B2 (en) | 2012-11-28 | 2018-04-12 | Ngm Biopharmaceuticals, Inc. | Compositions and methods for treatment of metabolic disorders and diseases |
US9290557B2 (en) | 2012-11-28 | 2016-03-22 | Ngm Biopharmaceuticals, Inc. | Compositions comprising variants and fusions of FGF19 polypeptides |
DK2938740T3 (da) | 2012-12-27 | 2022-06-20 | Ngm Biopharmaceuticals Inc | Kimære fgf19-peptider til anvendelse til behandling af galdesyrelidelser |
US9273107B2 (en) | 2012-12-27 | 2016-03-01 | Ngm Biopharmaceuticals, Inc. | Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases |
SG11201602870YA (en) | 2013-10-28 | 2016-05-30 | Ngm Biopharmaceuticals Inc | Cancer models and associated methods |
UA119863C2 (uk) | 2014-01-24 | 2019-08-27 | Нгм Біофармасьютікалс, Інк. | Антитіло або його фрагмент, що зв'язується з бета-клото |
WO2015183890A2 (fr) | 2014-05-28 | 2015-12-03 | Ngm Biopharmaceuticals, Inc. | Méthodes et compositions pour le traitement de maladies et de troubles métaboliques |
AU2015277438B2 (en) | 2014-06-16 | 2020-02-27 | Ngm Biopharmaceuticals, Inc. | Methods and uses for modulating bile acid homeostasis and treatment of bile acid disorders and diseases |
CN107108711B (zh) | 2014-10-23 | 2021-11-23 | 恩格姆生物制药公司 | 包含肽变异体的药物组合物及其使用方法 |
US10434144B2 (en) | 2014-11-07 | 2019-10-08 | Ngm Biopharmaceuticals, Inc. | Methods for treatment of bile acid-related disorders and prediction of clinical sensitivity to treatment of bile acid-related disorders |
KR20170084332A (ko) | 2014-12-04 | 2017-07-19 | 노파르티스 아게 | Klotho 변이체 폴리펩티드를 사용하는 방법 및 조성물 |
US10800843B2 (en) | 2015-07-29 | 2020-10-13 | Ngm Biopharmaceuticals, Inc. | Beta klotho-binding proteins |
JP6728352B2 (ja) | 2015-11-09 | 2020-07-22 | エヌジーエム バイオファーマシューティカルス,インコーポレーテッド | 胆汁酸に関係した障害の治療方法 |
AU2017315459B2 (en) | 2016-08-26 | 2023-06-29 | Ngm Biopharmaceuticals, Inc. | Methods of treating fibroblast growth factor 19-mediated cancers and tumors |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000073454A1 (fr) * | 1999-06-02 | 2000-12-07 | Genentech, Inc. | Polypeptides transmembranaires secretes et acides nucleiques codants pour ceux-ci |
ATE397063T1 (de) * | 1997-11-25 | 2008-06-15 | Genentech Inc | Fibroblasten-wachstumsfaktor-19 |
AU3924300A (en) * | 1999-04-02 | 2000-10-23 | Millennium Pharmaceuticals, Inc. | Fibroblast growth factor-20 |
WO2001049740A1 (fr) * | 2000-01-05 | 2001-07-12 | Zymogenetics, Inc. | Nouvel homologue du fgf, zfgf12 |
-
2001
- 2001-02-15 EP EP01914373A patent/EP1257645A2/fr not_active Withdrawn
- 2001-02-15 AU AU39767/01A patent/AU3976701A/en not_active Abandoned
- 2001-02-15 MX MXPA02007619A patent/MXPA02007619A/es unknown
- 2001-02-15 CA CA002398603A patent/CA2398603A1/fr not_active Abandoned
- 2001-02-15 JP JP2001560377A patent/JP2005508131A/ja not_active Withdrawn
- 2001-02-15 WO PCT/US2001/004778 patent/WO2001061007A2/fr active Search and Examination
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011519043A (ja) * | 2008-04-29 | 2011-06-30 | ノバルティス アーゲー | 線維芽細胞増殖因子受容体のキナーゼ活性のモジュレーションをモニタリングする方法、および該方法の使用 |
Also Published As
Publication number | Publication date |
---|---|
WO2001061007A3 (fr) | 2002-03-14 |
CA2398603A1 (fr) | 2001-08-23 |
AU3976701A (en) | 2001-08-27 |
WO2001061007A9 (fr) | 2002-04-18 |
EP1257645A2 (fr) | 2002-11-20 |
WO2001061007A2 (fr) | 2001-08-23 |
MXPA02007619A (es) | 2002-12-13 |
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