JP2005506971A5 - - Google Patents

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Publication number
JP2005506971A5
JP2005506971A5 JP2003518542A JP2003518542A JP2005506971A5 JP 2005506971 A5 JP2005506971 A5 JP 2005506971A5 JP 2003518542 A JP2003518542 A JP 2003518542A JP 2003518542 A JP2003518542 A JP 2003518542A JP 2005506971 A5 JP2005506971 A5 JP 2005506971A5
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JP
Japan
Prior art keywords
accession number
mrp1
mrp1 gene
gene
position corresponding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2003518542A
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English (en)
Japanese (ja)
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JP2005506971A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2002/008200 external-priority patent/WO2003013533A2/en
Publication of JP2005506971A publication Critical patent/JP2005506971A/ja
Publication of JP2005506971A5 publication Critical patent/JP2005506971A5/ja
Withdrawn legal-status Critical Current

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JP2003518542A 2001-07-23 2002-07-23 Mrp1に基づいたがんの改善治療の手段及び方法 Withdrawn JP2005506971A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01117608 2001-07-23
EP02011710 2002-05-24
PCT/EP2002/008200 WO2003013533A2 (en) 2001-07-23 2002-07-23 Methods for improved treatment of cancer with irinotecan based on mrp1

Publications (2)

Publication Number Publication Date
JP2005506971A JP2005506971A (ja) 2005-03-10
JP2005506971A5 true JP2005506971A5 (https=) 2006-01-05

Family

ID=26076655

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2003518546A Withdrawn JP2005501840A (ja) 2001-07-23 2002-07-23 癌の改良された治療のための手段および方法
JP2003518543A Withdrawn JP2005504759A (ja) 2001-07-23 2002-07-23 Cyp3a5に基づいたがんの改善治療の手段及び方法
JP2003518542A Withdrawn JP2005506971A (ja) 2001-07-23 2002-07-23 Mrp1に基づいたがんの改善治療の手段及び方法
JP2003518545A Withdrawn JP2005505526A (ja) 2001-07-23 2002-07-23 Ugt1a1に基づいたがんの改善治療の手段及び方法
JP2003518544A Withdrawn JP2005508312A (ja) 2001-07-23 2002-07-23 Mdr1に基づいた癌治療の改善のための手段および方法

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2003518546A Withdrawn JP2005501840A (ja) 2001-07-23 2002-07-23 癌の改良された治療のための手段および方法
JP2003518543A Withdrawn JP2005504759A (ja) 2001-07-23 2002-07-23 Cyp3a5に基づいたがんの改善治療の手段及び方法

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2003518545A Withdrawn JP2005505526A (ja) 2001-07-23 2002-07-23 Ugt1a1に基づいたがんの改善治療の手段及び方法
JP2003518544A Withdrawn JP2005508312A (ja) 2001-07-23 2002-07-23 Mdr1に基づいた癌治療の改善のための手段および方法

Country Status (6)

Country Link
US (1) US20050032724A1 (https=)
EP (5) EP1408973A2 (https=)
JP (5) JP2005501840A (https=)
AU (5) AU2002328945A1 (https=)
CA (5) CA2454627A1 (https=)
WO (5) WO2003013537A2 (https=)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4096037B2 (ja) * 2002-08-12 2008-06-04 国立大学法人滋賀医科大学 グルクロン酸転移酵素遺伝子の変異解析による薬剤代謝活性の予測方法
US6916627B2 (en) 2002-11-27 2005-07-12 St. Jude Children's Research Hospital ATM kinase compositions and methods
US7108992B2 (en) 2002-11-27 2006-09-19 St. Jude Children's Research Hospital ATM kinase compositions and methods
ES2308208T3 (es) 2003-05-30 2008-12-01 University Of Chicago Metodos y composiciones para predecir la toxicidad del irinotecano.
WO2005028645A1 (ja) * 2003-09-24 2005-03-31 Kyushu Tlo Company, Limited MDR1遺伝子の5’制御領域におけるSNPs
BRPI0415079A (pt) * 2003-10-06 2006-12-12 Novartis Ag biomarcadores para prognóstico de diarréia induzida por droga
JP2005245362A (ja) * 2004-03-05 2005-09-15 Kyowa Medex Co Ltd 肺癌および頭頸部癌の発症危険率を予測する方法
US20070207149A1 (en) * 2004-04-27 2007-09-06 Wellstat Biologics Corporation Cancer treatment using viruses and camptothecins
ES2429041T3 (es) * 2004-06-18 2013-11-12 Genentech, Inc. Combinación de un agente quimioterapéutico y un antagonista de un producto génico para tratar tumores
WO2006076288A2 (en) * 2005-01-11 2006-07-20 Five Prime Therapeutics, Inc. Dna constructs for long-term expression of intravascularly injected naked dna
JP2007060967A (ja) * 2005-08-30 2007-03-15 Tokyo Institute Of Technology 遺伝子多型の検出方法および薬物のスクリーニング方法
US20090325156A1 (en) * 2005-11-10 2009-12-31 Government of the United States of America, as Represented by Secretary, Dept. of Human Services Materials and methods for abcb1 polymorphic variant screening, diagnosis, and treatment
KR101107911B1 (ko) * 2006-11-30 2012-01-25 아크레이 가부시키가이샤 Ugt1a1 유전자 증폭용 프라이머 셋트, 그것을 포함하는ugt1a1 유전자 증폭용 시약 및 그 용도
WO2010099508A1 (en) * 2009-02-26 2010-09-02 Theraquest Biosciences, Inc. Extended release oral pharmaceutical compositions of 3-hydroxy-n-methylmorphinan and method of use
WO2011031974A1 (en) * 2009-09-10 2011-03-17 Southern Research Institute Acridine analogs in the treatment of gliomas
EP2542155B1 (en) 2010-03-01 2015-11-04 TAU Therapeutics LLC Method for imaging a disease
JP2011250726A (ja) * 2010-06-01 2011-12-15 Toyo Kohan Co Ltd イリノテカンの副作用の発生危険度を判定する方法及びそのためのキット
JP5945270B2 (ja) 2010-07-20 2016-07-05 バヴァリアン・ノルディック・アクティーゼルスカブ 発現産物を採取するための方法
US9717724B2 (en) 2012-06-13 2017-08-01 Ipsen Biopharm Ltd. Methods for treating pancreatic cancer using combination therapies
AU2013202947B2 (en) 2012-06-13 2016-06-02 Ipsen Biopharm Ltd. Methods for treating pancreatic cancer using combination therapies comprising liposomal irinotecan
KR102271848B1 (ko) * 2013-11-01 2021-07-01 피트니 파마슈티컬스 피티와이 리미티드 암 치료용 약학적 배합물
CA2962476C (en) * 2014-09-26 2023-09-26 Hi-Stem Ggmbh Novel methods for sub-typing and treating cancer
JP2016088919A (ja) * 2014-11-11 2016-05-23 国立研究開発法人産業技術総合研究所 イベルメクチン又はミルベマイシンdを有効成分として含む抗癌剤
CN107208163B (zh) * 2015-02-17 2021-01-08 国立大学法人山口大学 辅助对伊立替康副作用的发生风险的预测的方法
US11318131B2 (en) 2015-05-18 2022-05-03 Ipsen Biopharm Ltd. Nanoliposomal irinotecan for use in treating small cell lung cancer
JP7042739B2 (ja) 2015-08-20 2022-03-28 イプセン バイオファーム リミティド 癌処置のためのリポソーム型イリノテカン及びparp阻害薬を使用する併用療法
TW202400181A (zh) 2015-08-21 2024-01-01 英商益普生生物製藥有限公司 使用包含微脂伊立替康(irinotecan)及奧沙利鉑(oxaliplatin)之組合療法治療轉移性胰臟癌的方法
CN110402163A (zh) 2016-11-02 2019-11-01 易普森生物制药有限公司 使用包括脂质体伊立替康、奥沙利铂、5-氟尿嘧啶(和甲酰四氢叶酸)的组合疗法治疗胃癌
CN109939115B (zh) * 2019-05-06 2021-11-02 河南中医药大学 一种治疗放射性直肠炎的复方栓剂
US20230310478A1 (en) * 2020-09-02 2023-10-05 Ann And Robert H. Lurie Children's Hospital Of Chicago Methods and compositions for the treatment of pulmonary hypertension and cancer
CN114224875B (zh) * 2021-11-04 2023-08-11 中南大学湘雅医院 醇类化合物的新用途及抗肿瘤药物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998037892A1 (en) * 1997-02-27 1998-09-03 Pharmacia & Upjohn Company Tamoxifen as a therapy to reduce irinotecan hydrochloride-induced diarrhea
AU2592600A (en) * 1998-12-23 2000-07-31 G.D. Searle & Co. Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
US6395481B1 (en) * 1999-02-16 2002-05-28 Arch Development Corp. Methods for detection of promoter polymorphism in a UGT gene promoter
CA2295429A1 (en) * 2000-01-06 2001-07-06 Michael Michael Treatment or prevention of diarrhea
DE60120917T2 (de) * 2000-01-26 2007-01-25 Schering Corp. Kombinationspräparat zur krebstherapie
EP1286671B1 (en) * 2000-05-15 2006-04-05 Celgene Corporation Compositions for the treatment of colorectal cancer comprising thalidomide and irinotecan
WO2002028380A2 (en) * 2000-10-06 2002-04-11 Bristol-Myers Squibb Company Oral dosage forms for administration of the combination of tegafur, uracil, folinic acid, and irinotecan and method of using the same

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