CA2454640A1 - Methods for treatment of cancer using irinotecan based on ugt1a1 - Google Patents
Methods for treatment of cancer using irinotecan based on ugt1a1 Download PDFInfo
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- CA2454640A1 CA2454640A1 CA002454640A CA2454640A CA2454640A1 CA 2454640 A1 CA2454640 A1 CA 2454640A1 CA 002454640 A CA002454640 A CA 002454640A CA 2454640 A CA2454640 A CA 2454640A CA 2454640 A1 CA2454640 A1 CA 2454640A1
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- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01117608 | 2001-07-23 | ||
| EP01117608.8 | 2001-07-23 | ||
| EP02011710.7 | 2002-05-24 | ||
| EP02011710 | 2002-05-24 | ||
| PCT/EP2002/008217 WO2003013536A2 (en) | 2001-07-23 | 2002-07-23 | Methods for treatment of cancer using irinotecan based on ugt1a1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2454640A1 true CA2454640A1 (en) | 2003-02-20 |
Family
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Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002454640A Abandoned CA2454640A1 (en) | 2001-07-23 | 2002-07-23 | Methods for treatment of cancer using irinotecan based on ugt1a1 |
| CA002454643A Abandoned CA2454643A1 (en) | 2001-07-23 | 2002-07-23 | Methods for the treatment of cancer with irinotecan based on cyp3a5 |
| CA002454637A Abandoned CA2454637A1 (en) | 2001-07-23 | 2002-07-23 | Use of irinotecan for improved treatment of cancer based on mdr1 |
| CA002454648A Abandoned CA2454648A1 (en) | 2001-07-23 | 2002-07-23 | Irinotecan for treatment of cancer |
| CA002454627A Abandoned CA2454627A1 (en) | 2001-07-23 | 2002-07-23 | Methods for improved treatment of cancer with irinotecan based on mrp1 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002454643A Abandoned CA2454643A1 (en) | 2001-07-23 | 2002-07-23 | Methods for the treatment of cancer with irinotecan based on cyp3a5 |
| CA002454637A Abandoned CA2454637A1 (en) | 2001-07-23 | 2002-07-23 | Use of irinotecan for improved treatment of cancer based on mdr1 |
| CA002454648A Abandoned CA2454648A1 (en) | 2001-07-23 | 2002-07-23 | Irinotecan for treatment of cancer |
| CA002454627A Abandoned CA2454627A1 (en) | 2001-07-23 | 2002-07-23 | Methods for improved treatment of cancer with irinotecan based on mrp1 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20050032724A1 (https=) |
| EP (5) | EP1408972A2 (https=) |
| JP (5) | JP2005504759A (https=) |
| AU (5) | AU2002328945A1 (https=) |
| CA (5) | CA2454640A1 (https=) |
| WO (5) | WO2003013534A2 (https=) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP4096037B2 (ja) * | 2002-08-12 | 2008-06-04 | 国立大学法人滋賀医科大学 | グルクロン酸転移酵素遺伝子の変異解析による薬剤代謝活性の予測方法 |
| US7108992B2 (en) | 2002-11-27 | 2006-09-19 | St. Jude Children's Research Hospital | ATM kinase compositions and methods |
| US6916627B2 (en) | 2002-11-27 | 2005-07-12 | St. Jude Children's Research Hospital | ATM kinase compositions and methods |
| JP2006526412A (ja) | 2003-05-30 | 2006-11-24 | ユニバーシティ オブ シカゴ | イリノテカン毒性を推定する方法および組成物 |
| JPWO2005028645A1 (ja) * | 2003-09-24 | 2007-11-15 | 株式会社産学連携機構九州 | ＭＤＲ１遺伝子の５’制御領域におけるＳＮＰｓ |
| BRPI0415079A (pt) * | 2003-10-06 | 2006-12-12 | Novartis Ag | biomarcadores para prognóstico de diarréia induzida por droga |
| JP2005245362A (ja) * | 2004-03-05 | 2005-09-15 | Kyowa Medex Co Ltd | 肺癌および頭頸部癌の発症危険率を予測する方法 |
| NZ550430A (en) * | 2004-04-27 | 2009-06-26 | Wellstat Biologics Corp | Cancer treatment using viruses and camptothecins |
| WO2006009805A2 (en) * | 2004-06-18 | 2006-01-26 | Genentech, Inc. | Combination of a chemotherapeutic agent and an antagonist of a gene product for treating tumors |
| WO2006076288A2 (en) * | 2005-01-11 | 2006-07-20 | Five Prime Therapeutics, Inc. | Dna constructs for long-term expression of intravascularly injected naked dna |
| JP2007060967A (ja) * | 2005-08-30 | 2007-03-15 | Tokyo Institute Of Technology | 遺伝子多型の検出方法および薬物のスクリーニング方法 |
| JP2009515524A (ja) * | 2005-11-10 | 2009-04-16 | アメリカ合衆国 | Ａｂｃｂ１多型バリアントスクリーニング、診断及び処置のための物質及び方法 |
| EP2463365B1 (en) | 2006-11-30 | 2013-09-18 | ARKRAY, Inc. | Probes for detection of UGT1A1 gene, reagent for detection of UGT1A1 gene comprising the same, and uses thereof |
| EP2448406B1 (en) * | 2009-02-26 | 2016-04-20 | Relmada Therapeutics, Inc. | Extended release oral pharmaceutical compositions of 3-hydroxy-n-methylmorphinan and method of use |
| WO2011031974A1 (en) * | 2009-09-10 | 2011-03-17 | Southern Research Institute | Acridine analogs in the treatment of gliomas |
| AU2011223883B2 (en) | 2010-03-01 | 2015-10-08 | Cavion, Inc. | Cancer diagnosis and imaging |
| JP2011250726A (ja) * | 2010-06-01 | 2011-12-15 | Toyo Kohan Co Ltd | イリノテカンの副作用の発生危険度を判定する方法及びそのためのキット |
| AU2011281982B2 (en) | 2010-07-20 | 2015-12-17 | Bavarian Nordic A/S | Method for harvesting expression products |
| US9717724B2 (en) | 2012-06-13 | 2017-08-01 | Ipsen Biopharm Ltd. | Methods for treating pancreatic cancer using combination therapies |
| AU2013202947B2 (en) | 2012-06-13 | 2016-06-02 | Ipsen Biopharm Ltd. | Methods for treating pancreatic cancer using combination therapies comprising liposomal irinotecan |
| KR102271848B1 (ko) * | 2013-11-01 | 2021-07-01 | 피트니 파마슈티컬스 피티와이 리미티드 | 암 치료용 약학적 배합물 |
| ES2843829T3 (es) * | 2014-09-26 | 2021-07-20 | Hi Stem Ggmbh Im Deutschen Krebsforschungszentrum Dkfz | Nuevos métodos para la subtipificación y el tratamiento del cáncer |
| JP2016088919A (ja) * | 2014-11-11 | 2016-05-23 | 国立研究開発法人産業技術総合研究所 | イベルメクチン又はミルベマイシンｄを有効成分として含む抗癌剤 |
| CN107208163B (zh) | 2015-02-17 | 2021-01-08 | 国立大学法人山口大学 | 辅助对伊立替康副作用的发生风险的预测的方法 |
| US11318131B2 (en) | 2015-05-18 | 2022-05-03 | Ipsen Biopharm Ltd. | Nanoliposomal irinotecan for use in treating small cell lung cancer |
| EP3337467B1 (en) | 2015-08-20 | 2020-12-09 | Ipsen Biopharm Ltd. | Combination therapy using liposomal irinotecan and a parp inhibitor for cancer treatment |
| MX385425B (es) | 2015-08-21 | 2025-03-18 | Ipsen Biopharm Ltd | Irinotecán liposomal y oxaliplatino, 5-fluoroacilo y leucovorina para usarse en el tratamiento de cáncer pancreático metastásico. |
| EP3535026A1 (en) | 2016-11-02 | 2019-09-11 | Ipsen Biopharm Limited | Treating gastric cancer using combination therapies comprising liposomal irinotecan, oxaliplatin, 5-fluoruracil (and leucovorin) |
| CN109939115B (zh) * | 2019-05-06 | 2021-11-02 | 河南中医药大学 | 一种治疗放射性直肠炎的复方栓剂 |
| US20230310478A1 (en) * | 2020-09-02 | 2023-10-05 | Ann And Robert H. Lurie Children's Hospital Of Chicago | Methods and compositions for the treatment of pulmonary hypertension and cancer |
| CN114224875B (zh) * | 2021-11-04 | 2023-08-11 | 中南大学湘雅医院 | 醇类化合物的新用途及抗肿瘤药物 |
Family Cites Families (7)
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| CA2280855A1 (en) * | 1997-02-27 | 1998-09-03 | Pharmacia & Upjohn Company | Tamoxifen as a therapy to reduce irinotecan hydrochloride-induced diarrhea |
| BR9916536A (pt) * | 1998-12-23 | 2002-01-02 | Searle & Co | Método para o tratamento ou prevenção de um distúrbio de neoplasia em um mamìfero em necessidade deste tratamento ou prevenção, e, combinação |
| US6395481B1 (en) * | 1999-02-16 | 2002-05-28 | Arch Development Corp. | Methods for detection of promoter polymorphism in a UGT gene promoter |
| CA2295429A1 (en) * | 2000-01-06 | 2001-07-06 | Michael Michael | Treatment or prevention of diarrhea |
| EP1251850B1 (en) * | 2000-01-26 | 2006-06-21 | Schering Corporation | Use of a combination preparation in cancer therapy |
| WO2001087306A2 (en) * | 2000-05-15 | 2001-11-22 | Celgene Corp. | Compositions and methods for the treatment of colorectal cancer |
| US20020169141A1 (en) * | 2000-10-06 | 2002-11-14 | Christophe Martin | Oral dosage forms for administration of the combination of tegafur, uracil, folinic acid, and irinotecan and method of using the same |
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2002
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- 2002-07-23 CA CA002454640A patent/CA2454640A1/en not_active Abandoned
- 2002-07-23 CA CA002454643A patent/CA2454643A1/en not_active Abandoned
- 2002-07-23 EP EP02764764A patent/EP1408972A2/en not_active Ceased
- 2002-07-23 EP EP02764763A patent/EP1438050A2/en not_active Withdrawn
- 2002-07-23 AU AU2002331290A patent/AU2002331290A1/en not_active Abandoned
- 2002-07-23 EP EP02767255A patent/EP1408975A2/en not_active Withdrawn
- 2002-07-23 AU AU2002328952A patent/AU2002328952A1/en not_active Abandoned
- 2002-07-23 EP EP02764762A patent/EP1408974A2/en not_active Withdrawn
- 2002-07-23 AU AU2002328950A patent/AU2002328950A1/en not_active Abandoned
- 2002-07-23 CA CA002454637A patent/CA2454637A1/en not_active Abandoned
- 2002-07-23 JP JP2003518543A patent/JP2005504759A/ja not_active Withdrawn
- 2002-07-23 JP JP2003518545A patent/JP2005505526A/ja not_active Withdrawn
- 2002-07-23 WO PCT/EP2002/008219 patent/WO2003013534A2/en not_active Ceased
- 2002-07-23 WO PCT/EP2002/008220 patent/WO2003013535A2/en not_active Ceased
- 2002-07-23 WO PCT/EP2002/008218 patent/WO2003013537A2/en not_active Ceased
- 2002-07-23 EP EP02764757A patent/EP1408973A2/en not_active Withdrawn
- 2002-07-23 JP JP2003518542A patent/JP2005506971A/ja not_active Withdrawn
- 2002-07-23 US US10/484,577 patent/US20050032724A1/en not_active Abandoned
- 2002-07-23 JP JP2003518546A patent/JP2005501840A/ja not_active Withdrawn
- 2002-07-23 AU AU2002328953A patent/AU2002328953A1/en not_active Abandoned
- 2002-07-23 WO PCT/EP2002/008217 patent/WO2003013536A2/en not_active Ceased
- 2002-07-23 CA CA002454648A patent/CA2454648A1/en not_active Abandoned
- 2002-07-23 WO PCT/EP2002/008200 patent/WO2003013533A2/en not_active Ceased
- 2002-07-23 CA CA002454627A patent/CA2454627A1/en not_active Abandoned
- 2002-07-23 JP JP2003518544A patent/JP2005508312A/ja not_active Withdrawn
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