BRPI0415079A - biomarcadores para prognóstico de diarréia induzida por droga - Google Patents
biomarcadores para prognóstico de diarréia induzida por drogaInfo
- Publication number
- BRPI0415079A BRPI0415079A BRPI0415079-1A BRPI0415079A BRPI0415079A BR PI0415079 A BRPI0415079 A BR PI0415079A BR PI0415079 A BRPI0415079 A BR PI0415079A BR PI0415079 A BRPI0415079 A BR PI0415079A
- Authority
- BR
- Brazil
- Prior art keywords
- biomarkers
- prognosis
- drug
- induced diarrhea
- diarrhea
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
"BIOMARCADORES PARA PROGNóSTICO DE DIARRéIA INDUZIDA POR DROGA". A presente invenção refere-se a biomarcadores para o prognóstico da diarréia com base na expressão genética de alguns genes pelo indivíduo, na expressão do tipo de sangue Diego pelo indivíduo, ou nos resultados das análises hematológicas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50897303P | 2003-10-06 | 2003-10-06 | |
PCT/EP2004/011122 WO2005039573A2 (en) | 2003-10-06 | 2004-10-05 | Biomarkers for the prediction of drug-induced diarrhoea |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0415079A true BRPI0415079A (pt) | 2006-12-12 |
Family
ID=34520004
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0415079-1A BRPI0415079A (pt) | 2003-10-06 | 2004-10-05 | biomarcadores para prognóstico de diarréia induzida por droga |
Country Status (9)
Country | Link |
---|---|
US (1) | US20070289889A1 (pt) |
EP (1) | EP1673631A2 (pt) |
JP (1) | JP2007509604A (pt) |
CN (1) | CN1875275A (pt) |
AU (1) | AU2004283428A1 (pt) |
BR (1) | BRPI0415079A (pt) |
CA (1) | CA2541097A1 (pt) |
MX (1) | MXPA06003826A (pt) |
WO (1) | WO2005039573A2 (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005111605A2 (en) * | 2004-05-17 | 2005-11-24 | Novartis Ag | Biomarkers for the prediction and treatment of drug-induced diarrhoea |
JP2009532035A (ja) * | 2006-03-31 | 2009-09-10 | ブリストル−マイヤーズ スクイブ カンパニー | 微小管安定化剤に対する感受性を決定するためのバイオマーカーおよび方法 |
CN103217534A (zh) * | 2012-01-20 | 2013-07-24 | 上海市公共卫生临床中心 | 肺癌标志物sbp-1及其用途 |
CN108456725B (zh) * | 2017-07-26 | 2019-06-21 | 湖北文理学院 | Tm9sf1基因作为靶点在血管性疾病中的应用 |
CN109943640B (zh) * | 2017-12-20 | 2021-08-03 | 华中农业大学 | 与母鸡储精能力相关的snp分子标记及其应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4686479A (en) * | 1985-07-22 | 1987-08-11 | Young Chung C | Apparatus and control kit for analyzing blood sample values including hematocrit |
WO2000003024A2 (en) * | 1998-07-10 | 2000-01-20 | The Rockefeller University | Alleles of the human mu opioid receptor, diagnostic methods using said alleles, and methods of treatment based thereon |
DE60142309D1 (de) * | 2000-12-12 | 2010-07-15 | Nagoya Ind Science Res I Nagoy | On einer durch die verabreichung einer verbindung, die entweder per se durch ugt1a1 metabolisiert wird oder deren zwischenverbindung durch das enzym metabolisiert wird, hervorgerufenen unerwünschten arzneimittelwirkung |
JP2005506971A (ja) * | 2001-07-23 | 2005-03-10 | エピダウロス・バイオテクノロジー・アクチェンゲゼルシャフト | Mrp1に基づいたがんの改善治療の手段及び方法 |
-
2004
- 2004-10-05 MX MXPA06003826A patent/MXPA06003826A/es not_active Application Discontinuation
- 2004-10-05 EP EP04765829A patent/EP1673631A2/en not_active Withdrawn
- 2004-10-05 WO PCT/EP2004/011122 patent/WO2005039573A2/en active Application Filing
- 2004-10-05 CN CNA2004800316780A patent/CN1875275A/zh active Pending
- 2004-10-05 BR BRPI0415079-1A patent/BRPI0415079A/pt not_active IP Right Cessation
- 2004-10-05 US US10/574,769 patent/US20070289889A1/en not_active Abandoned
- 2004-10-05 CA CA002541097A patent/CA2541097A1/en not_active Abandoned
- 2004-10-05 AU AU2004283428A patent/AU2004283428A1/en not_active Abandoned
- 2004-10-05 JP JP2006530096A patent/JP2007509604A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2004283428A1 (en) | 2005-05-06 |
MXPA06003826A (es) | 2006-06-14 |
EP1673631A2 (en) | 2006-06-28 |
JP2007509604A (ja) | 2007-04-19 |
US20070289889A1 (en) | 2007-12-20 |
WO2005039573A2 (en) | 2005-05-06 |
CA2541097A1 (en) | 2005-05-06 |
WO2005039573A3 (en) | 2006-02-16 |
CN1875275A (zh) | 2006-12-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE470723T1 (de) | Genexpressionsmarker für die prognose von brustkrebs | |
BR0212211A (pt) | Diagnóstico de carcinomas | |
BR0011849A (pt) | Anticorpos enxertados lm609 melhorados | |
ATE437184T1 (de) | Varianten der fc-region | |
BRPI0513297A (pt) | polipeptìdeo | |
BR0300316A (pt) | Método para selecionar uma fonte | |
DK1103564T3 (da) | Cancerantigener baseret på tumorsuppressorgen WT1-produkt | |
ATE541944T1 (de) | Polynukleotidprimer | |
BRPI0505311A (pt) | escada rolante com escovas do degrau, degrau de uma escada rolante desse tipo, bem como, processo para a modernização de uma escada rolante | |
BRPI0415079A (pt) | biomarcadores para prognóstico de diarréia induzida por droga | |
BR0111668A (pt) | Liga de aço, ferramenta de moldagem plástica e blank temperado rijo para ferramentas de moldagem plástica | |
AR036202A1 (es) | Composiciones y metodos relacionados con el cluster genico biosintetico de daptomicina | |
DE502006005725D1 (de) | Herstellung von 3-(alkylthio)propanal | |
BRPI0418229A (pt) | genes do ciclo celular e métodos corrrelatos de uso | |
BR0107861A (pt) | Polissiloxanos para hidrofobização | |
BR0315178A (pt) | Eritropoietina: remodelagem e glicoconjugação de eritropoietina | |
BR0212265A (pt) | Método para a determinação de analisados múltiplos | |
DE602005017788D1 (de) | Diagnose- und prognoseverfahren der nichtalkoholischen steatohepatitis (nash) | |
BRPI0414365A (pt) | composições, reagentes e kits para, e métodos de diagnosticar, monitorar e tratar obesidade e/ou diabetes | |
BR0102431A (pt) | Célula de têmpera com gás | |
ATE441712T1 (de) | Die nukleotidsequenz ann bindende zink-finger domänen | |
ATE466958T1 (de) | Klassifizierung von kolonkrebs | |
DE602005016290D1 (de) | Glichkeit | |
DE50213492D1 (de) | Nukleinsäuresequenz, die für das OPCA Gen kodiert | |
BR0312770A (pt) | Detecção de microorganismos |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 4A, 5A, 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012. |