JP2005506947A5 - - Google Patents

Download PDF

Info

Publication number
JP2005506947A5
JP2005506947A5 JP2000593637A JP2000593637A JP2005506947A5 JP 2005506947 A5 JP2005506947 A5 JP 2005506947A5 JP 2000593637 A JP2000593637 A JP 2000593637A JP 2000593637 A JP2000593637 A JP 2000593637A JP 2005506947 A5 JP2005506947 A5 JP 2005506947A5
Authority
JP
Japan
Prior art keywords
compound
formula
xix
xiv
xiii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2000593637A
Other languages
English (en)
Japanese (ja)
Other versions
JP4712975B2 (ja
JP2005506947A (ja
Filing date
Publication date
Priority claimed from US09/452,406 external-priority patent/US7238711B1/en
Application filed filed Critical
Priority claimed from PCT/US2000/000821 external-priority patent/WO2000042071A2/en
Publication of JP2005506947A publication Critical patent/JP2005506947A/ja
Publication of JP2005506947A5 publication Critical patent/JP2005506947A5/ja
Application granted granted Critical
Publication of JP4712975B2 publication Critical patent/JP4712975B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2000593637A 1999-01-12 2000-01-12 炎症反応を阻害又は増強するための組成物及び方法 Expired - Fee Related JP4712975B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US22907199A 1999-01-12 1999-01-12
US09/229,071 1999-01-12
US27119299A 1999-03-17 1999-03-17
US09/271,192 1999-03-17
US09/452,406 1999-12-01
US09/452,406 US7238711B1 (en) 1999-03-17 1999-12-01 Compounds and methods to inhibit or augment an inflammatory response
PCT/US2000/000821 WO2000042071A2 (en) 1999-01-12 2000-01-12 Compounds and methods to inhibit or augment an inflammatory response

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010043809A Division JP5351078B2 (ja) 1999-01-12 2010-03-01 炎症反応を阻害又は増強するための組成物及び方法

Publications (3)

Publication Number Publication Date
JP2005506947A JP2005506947A (ja) 2005-03-10
JP2005506947A5 true JP2005506947A5 (https=) 2006-01-05
JP4712975B2 JP4712975B2 (ja) 2011-06-29

Family

ID=27397912

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2000593637A Expired - Fee Related JP4712975B2 (ja) 1999-01-12 2000-01-12 炎症反応を阻害又は増強するための組成物及び方法
JP2010043809A Expired - Fee Related JP5351078B2 (ja) 1999-01-12 2010-03-01 炎症反応を阻害又は増強するための組成物及び方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010043809A Expired - Fee Related JP5351078B2 (ja) 1999-01-12 2010-03-01 炎症反応を阻害又は増強するための組成物及び方法

Country Status (6)

Country Link
EP (2) EP2386565A3 (https=)
JP (2) JP4712975B2 (https=)
AU (1) AU2610000A (https=)
CA (2) CA2697598A1 (https=)
HK (1) HK1039784A1 (https=)
WO (1) WO2000042071A2 (https=)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6869606B1 (en) 1999-02-22 2005-03-22 Millennium Pharmaceuticals, Inc. Biotinylated-chemokine antibody complexes
MXPA01008465A (es) * 1999-02-22 2003-06-06 Millennium Pharm Inc Complejos de anticuerpo de quimiocina biotinilada.
WO2002060859A2 (en) 2000-12-20 2002-08-08 Bristol-Myers Squibb Company Cyclic derivatives as modulators of chemokine receptor activity
CA2432908A1 (en) 2000-12-20 2002-06-27 Bristol-Myers Squibb Pharma Company Diamines as modulators of chemokine receptor activity
DE102004054421B4 (de) * 2003-11-12 2019-06-27 Ajinomoto Co., Inc. Geliermittel für Öl
SI1691814T1 (sl) 2003-12-01 2012-11-30 Cambridge Entpr Ltd Protivnetna zdravila
RU2267496C2 (ru) * 2004-01-15 2006-01-10 Сергей Иванович Черныш Противоопухолевые и антивирусные пептиды
GB2418426A (en) 2004-08-18 2006-03-29 Univ Cambridge Tech Alpha-(acylamino)-bicyclolactam derivatives for treatment of inflammatory disorders
GB2418427A (en) 2004-09-02 2006-03-29 Univ Cambridge Tech Ligands for G-protein coupled receptors
GB0511060D0 (en) 2005-05-31 2005-07-06 Novartis Ag Organic compounds
GB0512238D0 (en) 2005-06-15 2005-07-27 Univ Cambridge Tech Anti-inflammatory agents
MX2008002101A (es) 2005-08-12 2008-04-19 Schering Corp Fusiones de la proteina-1 quimiotactica de monocito.
US9012152B2 (en) * 2007-01-09 2015-04-21 Yissum Research Development Company Of The Hebrew University Of Jerusalem Anti-bacterial peptides and methods of treating diseases using same
GB2452696B (en) 2007-08-02 2009-09-23 Cambridge Entpr Ltd 3-(2',2'-dimethylpropanoylamino)-tetrahydropyridin-2-one and its use in pharmaceutical compositions
GB2455539B (en) * 2007-12-12 2012-01-18 Cambridge Entpr Ltd Anti-inflammatory compositions and combinations
FR2941232B1 (fr) 2009-01-16 2014-08-08 Sederma Sa Nouveaux peptides, compositions les comprenant et utilisations cosmetiques et dermo-pharmaceutiques.
FR2941231B1 (fr) 2009-01-16 2016-04-01 Sederma Sa Nouveaux peptides, compositions les comprenant et utilisations cosmetiques et dermo-pharmaceutiques.
EP3744729B1 (en) 2009-01-16 2023-03-01 Sederma Peptides, compositions comprising them and cosmetic and dermopharmaceutical uses
US8524217B2 (en) 2010-05-11 2013-09-03 Merck Sharp & Dohme Corp. MCP1-Ig fusion variants
GB201009603D0 (en) 2010-06-08 2010-07-21 Cambridge Entpr Ltd Anti-inflammatory agent
CN102795977A (zh) * 2012-08-27 2012-11-28 昆明博鸿生物科技有限公司 一种(7z,11z,13e)-十六碳三烯醛的合成方法
EP2911701A4 (en) * 2012-10-23 2016-06-08 Univ Johns Hopkins Novel self-assembling drug amphiphiles and methods for synthesis and application
WO2014148136A1 (ja) * 2013-03-19 2014-09-25 岐阜市 抗アレルギー活性化合物及びその用途
ITRM20130199A1 (it) 2013-04-03 2014-10-04 Irbm Science Park S P A Peptidi per uso dermatologico e/o cosmetico
JP6856532B2 (ja) 2015-01-20 2021-04-07 エックスオーシー ファーマシューティカルズ インコーポレイテッドＸｏｃ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ エルゴリン化合物およびその使用
US11395820B2 (en) 2016-03-16 2022-07-26 H. Lee Moffitt Cancer Center And Research Institute, Inc. Small molecules against cereblon to enhance effector t cell function
EP3630758A1 (en) 2017-06-01 2020-04-08 Xoc Pharmaceuticals, Inc Ergoline derivatives for use in medicine
BR112021000395A2 (pt) 2018-07-11 2021-04-06 H. Lee Moffitt Cancer Center And Research Institute, Inc. Compostos imunomoduladores diméricos contra mecanismos baseados em cereblon
IT202000025423A1 (it) * 2020-10-27 2022-04-27 Ulisse Biomed S P A Uso di proteine per il trattamento di patologie associate a tossine formanti pori o a proteine virali
JP2024516327A (ja) * 2021-05-07 2024-04-12 ラテラル、ファーマ、プロプライエタリー、リミテッド 炎症性気道疾患を処置するための組成物及びその使用

Family Cites Families (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2857386A (en) * 1956-04-09 1958-10-21 Ciba Pharm Prod Inc Iso reserpic and iso deserpidic acids, salts and esters
US3119819A (en) * 1959-07-29 1964-01-28 Ciba Geigy Corp Intermediates for 18-o-alkyl-reserpic acid esters and related compounds
FR1451176A (fr) * 1962-01-11 1966-01-07 Procédé de préparation de dérivés de l'acide nicotinique des acides alpha-amino-carboxyliques
US3291800A (en) * 1963-07-23 1966-12-13 Warner Lambert Pharmaceutical 3-substituted derivatives of yohimbane alkaloids and process for their production
US3264303A (en) * 1964-04-06 1966-08-02 Ciba Geigy Corp Process for the manufacture of yohimbane-18-omicron-ethers
US4093709A (en) 1975-01-28 1978-06-06 Alza Corporation Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates)
US4051842A (en) 1975-09-15 1977-10-04 International Medical Corporation Electrode and interfacing pad for electrical physiological systems
HU172479B (hu) * 1976-03-09 1978-09-28 Gyogyszerkutato Intezet Sposob poluchenija novykh soedinenij s ehrgolenovymi i
DE2626348C3 (de) 1976-06-11 1980-01-31 Siemens Ag, 1000 Berlin Und 8000 Muenchen Implantierbare Dosiereinrichtung
NO812612L (no) 1980-08-06 1982-02-08 Ferring Pharma Ltd Enzym-inhibitorer.
US4383529A (en) 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
US4675189A (en) 1980-11-18 1987-06-23 Syntex (U.S.A.) Inc. Microencapsulation of water soluble active polypeptides
US4525359A (en) * 1982-12-10 1985-06-25 Greenway Frank L Iii Treatment for selective weight control
US5175343A (en) 1985-01-14 1992-12-29 Neorx Corporation Metal radionuclide labeled proteins for diagnosis and therapy
US4897255A (en) 1985-01-14 1990-01-30 Neorx Corporation Metal radionuclide labeled proteins for diagnosis and therapy
US5120526A (en) 1985-01-14 1992-06-09 Neorx Corporation Method of producing metal radionuclide labeled proteins for diagnosis and therapy
EP0215805A1 (en) * 1985-01-18 1987-04-01 MERCK PATENT GmbH Immunoregulatory peptides
JPS62501502A (ja) * 1985-01-18 1987-06-18 イミユーンテツク・フアーマシユーテイカルズ 免疫調節性ペプチド
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5045303A (en) 1985-05-17 1991-09-03 Neorx Corporation Radiohalogenated small molecules for protein labeling
US4877868A (en) 1986-03-12 1989-10-31 Neorx Corporation Radionuclide antibody coupling
US5560922A (en) 1986-05-30 1996-10-01 Rutgers, The State University Of New Jersey Transdermal absorption dosage unit using a polyacrylate adhesive polymer and process
US4879225A (en) 1986-06-20 1989-11-07 Neorx Corporation Enhanced production of antibodies utilizing insolubilized immune complexes
US4863713A (en) 1986-06-23 1989-09-05 The Board Of Trustees Of Leland Stanford Jr. Univ. Method and system for administering therapeutic and diagnostic agents
US5202118A (en) 1987-12-18 1993-04-13 Immunex Corporation Method for promoting wound healing using IL-1
US5091396A (en) 1988-07-20 1992-02-25 Monsanto Co. Pyridyl peptide mimetic compounds which are useful platelet-aggregation inhibitors
US4992463A (en) 1988-07-20 1991-02-12 Monsanto Company Thienyl peptide mimetic compounds which are useful in inhibiting platelet aggregation
GB8823869D0 (en) 1988-10-12 1988-11-16 Medical Res Council Production of antibodies
US5028594A (en) * 1988-12-27 1991-07-02 Naxcor Use of photodynamic compositions for cytotoxic effects
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5580774A (en) 1989-07-31 1996-12-03 Eli Lilly And Company Chimeric antibodies directed against a human glycoprotein antigen
US5661132A (en) 1989-12-14 1997-08-26 Auragen, Inc. Wound healing
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
US5625126A (en) 1990-08-29 1997-04-29 Genpharm International, Inc. Transgenic non-human animals for producing heterologous antibodies
ATE300615T1 (de) 1990-08-29 2005-08-15 Genpharm Int Transgene mäuse fähig zur produktion heterologer antikörper
US5650150A (en) 1990-11-09 1997-07-22 Gillies; Stephen D. Recombinant antibody cytokine fusion proteins
US5824647A (en) * 1990-12-12 1998-10-20 Postlethwaite; Arnold E. Chemotactic wound healing peptides
US5202169A (en) 1991-01-23 1993-04-13 Spendlove Max J Releasable fastener, method of releasably fastening, and releasable fastener dispenser
JPH06509578A (ja) 1991-07-26 1994-10-27 ユニバーシティ・オブ・ロチェスター 悪性細胞利用による癌治療法
US5326752A (en) * 1991-11-27 1994-07-05 Glycomed Incorporated Substituted lactose and lactosamine derivatives as cell adhesion inhibitors
US5624896A (en) 1992-06-09 1997-04-29 Neorx Corporation Clearing agents useful in pretargeting methods
US5616690A (en) 1992-06-09 1997-04-01 Neorx Corporation Hexose derivatized human serum albumin clearing agents
US5578287A (en) 1992-06-09 1996-11-26 Neorx Corporation Three-step pretargeting methods using improved biotin-active agent
EP1138334A3 (en) 1992-06-09 2002-04-03 Neorx Corporation Pretargeting methods and compounds
DK0710243T3 (da) 1993-06-29 2000-10-16 Ferring Bv Syntese af cykliske peptider
JPH09505555A (ja) * 1993-08-13 1997-06-03 ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ，アズ リプレゼンテッド バイ ザ セクレタリー，デパートメント オブ ヘルス アンド ヒューマン サービシーズ ＴＧＦ−βの活性を刺激および阻害する方法および組成物
US5459128A (en) * 1993-11-12 1995-10-17 Dana-Farber Cancer Institute Human monocyte chemoattractant protein-1 (MCP-1) derivatives
JPH09506106A (ja) 1993-12-07 1997-06-17 ネオルクス コーポレーション プレターゲティング方法及び化合物
US6303120B1 (en) 1994-03-15 2001-10-16 Memorial Sloan-Kettering Institute For Cancer Research Synthesis of glycoconjugates of the lewis y epitope and uses thereof
US5708163A (en) 1994-03-15 1998-01-13 Sloan-Kettering Institute Of Cancer Research Synthesis of the breast tumor-associated antigen defined by monoclonalantibody MBRL and uses thereof
JP3447809B2 (ja) * 1994-07-12 2003-09-16 花王株式会社 浴用剤
AU5528996A (en) * 1995-03-22 1996-10-08 Eli Lilly And Company Methods of treating or preventing pain or nociception
ATE377418T1 (de) 1995-06-07 2007-11-15 Poniard Pharmaceuticals Inc Vorbeugung und behandlung von kardiovaskulären beschwerden mit tamoxifen-analogen
US6265184B1 (en) 1995-12-20 2001-07-24 Icos Corporation Polynucleotides encoding chemokine receptor 88C
WO1997029192A1 (en) 1996-02-12 1997-08-14 Schering Corporation Mammalian dendritic cell chemokine reagents
US5667894A (en) 1996-06-05 1997-09-16 E. I. Du Pont De Nemours And Company Cathodic electrocoating compositions containing methane sulfonic acid as a neutralizing agent
GB9617923D0 (en) 1996-08-28 1996-10-09 Smithkline Beecham Plc Novel receptor
US5848956A (en) 1997-03-18 1998-12-15 Grettner; Norman L. Multi-purpose lat sling
US6214540B1 (en) * 1997-03-26 2001-04-10 University Of Maryland Biotechnology Institute Chemokines that inhibit immunodeficiency virus infection and methods based thereon
WO1998054326A1 (en) 1997-05-29 1998-12-03 Zymogenetics, Inc. Human chemokine zchemo-8
US6989435B2 (en) * 1997-09-11 2006-01-24 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
US5807482A (en) * 1997-10-31 1998-09-15 Uop Llc Chiral stationary phase based on yohimbinic acid

Similar Documents

Publication Publication Date Title
JP2005506947A5 (https=)
CA2363067A1 (en) Compounds and methods to inhibit or augment an inflammatory response
US8524229B2 (en) Medicament and a method for regulation of the vascular tone
JP4574007B2 (ja) ポリオール−ｉｆｎ−ベータ複体
DE69434725T2 (de) Zell- und Serumproteinanker und Konjugate
DE69631605T2 (de) Verfahren zur verringerung und zur erhaltung von verringerten blutspiegeln von lipiden mittels zubereitungen von ob-proteinen
US6063761A (en) Hepatoselective pharmaceutical actives
AU2004216823B2 (en) Pharmaceutical preparations containing thiazolidinediones for the treatment or prevention of IP-10 mediated diseases
JPH09505809A (ja) ヒドロキシカルバゾール化合物類による平滑筋移動および増殖の阻害
KR20010079669A (ko) 기질 활성의 조절
IL112427A (en) Production of pharmaceutical compositions comprising anti-tnf antibodies
JP2001514222A (ja) アムロジピン及びアトルバスタチンを含む治療用の組み合わせ
CA2352765A1 (en) Hapten-carrier conjugates for treating and preventing nicotine addiction
JP2001506609A (ja) 生理活性の増加した多量体エリスロポエチン
KR101058467B1 (ko) 부신피질 자극 호르몬 유사체 및 관련 방법
JPH03503632A (ja) 血液脳関門を経る治療薬の分別送達
JP2017031209A (ja) アタシセプトなどのＴＡＣＩ−Ｉｇ融合タンパク質を用いた自己免疫疾患を治療するための投薬法
JP2002538170A5 (https=)
JP2746832B2 (ja) 眼局所抗アレルギー剤
Herdman et al. Anticoagulants in renal disease in children
US9084761B2 (en) Use of interleukin-15 to treat cardiovascular diseases
JP2008526953A (ja) 炎症性疾患のプラジカンテルでの治療
JP2783403B2 (ja) リンパ節疾患及び後天性免疫不全症候群の病因物質からｔリンパ球を保護するための組成物及び方法
EA006881B1 (ru) ПРИМЕНЕНИЕ АКТИВАТОРОВ gp130 ПРИ ДИАБЕТИЧЕСКОЙ НЕВРОПАТИИ
JP2006511468A (ja) 内因性エリスロポエチンの組織保護活性を維持する長期作用性エリスロポエチン