JP2005506947A5 - - Google Patents
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- Publication number
- JP2005506947A5 JP2005506947A5 JP2000593637A JP2000593637A JP2005506947A5 JP 2005506947 A5 JP2005506947 A5 JP 2005506947A5 JP 2000593637 A JP2000593637 A JP 2000593637A JP 2000593637 A JP2000593637 A JP 2000593637A JP 2005506947 A5 JP2005506947 A5 JP 2005506947A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- formula
- xix
- xiv
- xiii
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 **C(*=C)C(NC(*)C(NC(CCC(*)=O)C(*)=O)=O)=* Chemical compound **C(*=C)C(NC(*)C(NC(CCC(*)=O)C(*)=O)=O)=* 0.000 description 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22907199A | 1999-01-12 | 1999-01-12 | |
| US09/229,071 | 1999-01-12 | ||
| US27119299A | 1999-03-17 | 1999-03-17 | |
| US09/271,192 | 1999-03-17 | ||
| US09/452,406 | 1999-12-01 | ||
| US09/452,406 US7238711B1 (en) | 1999-03-17 | 1999-12-01 | Compounds and methods to inhibit or augment an inflammatory response |
| PCT/US2000/000821 WO2000042071A2 (en) | 1999-01-12 | 2000-01-12 | Compounds and methods to inhibit or augment an inflammatory response |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010043809A Division JP5351078B2 (ja) | 1999-01-12 | 2010-03-01 | 炎症反応を阻害又は増強するための組成物及び方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005506947A JP2005506947A (ja) | 2005-03-10 |
| JP2005506947A5 true JP2005506947A5 (enExample) | 2006-01-05 |
| JP4712975B2 JP4712975B2 (ja) | 2011-06-29 |
Family
ID=27397912
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000593637A Expired - Fee Related JP4712975B2 (ja) | 1999-01-12 | 2000-01-12 | 炎症反応を阻害又は増強するための組成物及び方法 |
| JP2010043809A Expired - Fee Related JP5351078B2 (ja) | 1999-01-12 | 2010-03-01 | 炎症反応を阻害又は増強するための組成物及び方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010043809A Expired - Fee Related JP5351078B2 (ja) | 1999-01-12 | 2010-03-01 | 炎症反応を阻害又は増強するための組成物及び方法 |
Country Status (6)
| Country | Link |
|---|---|
| EP (2) | EP1141011A2 (enExample) |
| JP (2) | JP4712975B2 (enExample) |
| AU (1) | AU2610000A (enExample) |
| CA (2) | CA2363067C (enExample) |
| HK (1) | HK1039784A1 (enExample) |
| WO (1) | WO2000042071A2 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002537362A (ja) * | 1999-02-22 | 2002-11-05 | ミレニアム・ファーマシューティカルズ・インコーポレイテッド | ビオチン化ケモカイン抗体複合体 |
| US6869606B1 (en) | 1999-02-22 | 2005-03-22 | Millennium Pharmaceuticals, Inc. | Biotinylated-chemokine antibody complexes |
| AR035773A1 (es) | 2000-12-20 | 2004-07-14 | Bristol Myers Squibb Pharma Co | Compuestos diamino ciclico, composicion farmaceutica y su uso en la fabricacion de un medicamento util para modular la actividad de una quimioquina |
| CA2432908A1 (en) | 2000-12-20 | 2002-06-27 | Bristol-Myers Squibb Pharma Company | Diamines as modulators of chemokine receptor activity |
| DE102004054421B4 (de) * | 2003-11-12 | 2019-06-27 | Ajinomoto Co., Inc. | Geliermittel für Öl |
| JP5248779B2 (ja) | 2003-12-01 | 2013-07-31 | ケンブリッジ エンタープライズ リミティド | 抗炎症剤 |
| RU2267496C2 (ru) | 2004-01-15 | 2006-01-10 | Сергей Иванович Черныш | Противоопухолевые и антивирусные пептиды |
| GB2418426A (en) | 2004-08-18 | 2006-03-29 | Univ Cambridge Tech | Alpha-(acylamino)-bicyclolactam derivatives for treatment of inflammatory disorders |
| GB2418427A (en) | 2004-09-02 | 2006-03-29 | Univ Cambridge Tech | Ligands for G-protein coupled receptors |
| GB0511060D0 (en) | 2005-05-31 | 2005-07-06 | Novartis Ag | Organic compounds |
| GB0512238D0 (en) | 2005-06-15 | 2005-07-27 | Univ Cambridge Tech | Anti-inflammatory agents |
| WO2007021807A1 (en) | 2005-08-12 | 2007-02-22 | Schering Corporation | Mcp1 fusions |
| WO2008084478A2 (en) * | 2007-01-09 | 2008-07-17 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Anti-bacterial peptides and methods of treating diseases using same |
| GB2452696B (en) | 2007-08-02 | 2009-09-23 | Cambridge Entpr Ltd | 3-(2',2'-dimethylpropanoylamino)-tetrahydropyridin-2-one and its use in pharmaceutical compositions |
| GB2455539B (en) * | 2007-12-12 | 2012-01-18 | Cambridge Entpr Ltd | Anti-inflammatory compositions and combinations |
| EP3744729B1 (en) | 2009-01-16 | 2023-03-01 | Sederma | Peptides, compositions comprising them and cosmetic and dermopharmaceutical uses |
| FR2941232B1 (fr) * | 2009-01-16 | 2014-08-08 | Sederma Sa | Nouveaux peptides, compositions les comprenant et utilisations cosmetiques et dermo-pharmaceutiques. |
| FR2941231B1 (fr) * | 2009-01-16 | 2016-04-01 | Sederma Sa | Nouveaux peptides, compositions les comprenant et utilisations cosmetiques et dermo-pharmaceutiques. |
| US8524217B2 (en) | 2010-05-11 | 2013-09-03 | Merck Sharp & Dohme Corp. | MCP1-Ig fusion variants |
| GB201009603D0 (en) | 2010-06-08 | 2010-07-21 | Cambridge Entpr Ltd | Anti-inflammatory agent |
| CN102795977A (zh) * | 2012-08-27 | 2012-11-28 | 昆明博鸿生物科技有限公司 | 一种(7z,11z,13e)-十六碳三烯醛的合成方法 |
| US9180203B2 (en) * | 2012-10-23 | 2015-11-10 | The Johns Hopkins University | Self-assembling drug amphiphiles and methods for synthesis and use |
| WO2014148136A1 (ja) * | 2013-03-19 | 2014-09-25 | 岐阜市 | 抗アレルギー活性化合物及びその用途 |
| ITRM20130199A1 (it) | 2013-04-03 | 2014-10-04 | Irbm Science Park S P A | Peptidi per uso dermatologico e/o cosmetico |
| JP6856532B2 (ja) * | 2015-01-20 | 2021-04-07 | エックスオーシー ファーマシューティカルズ インコーポレイテッドXoc Pharmaceuticals, Inc | エルゴリン化合物およびその使用 |
| CN109153644B (zh) | 2016-03-16 | 2022-10-21 | H·李·莫菲特癌症中心研究有限公司 | 用以增强效应t细胞功能的针对cereblon的小分子 |
| CA3064274A1 (en) | 2017-06-01 | 2018-12-06 | Xoc Pharmaceuticals, Inc. | Ergoline derivatives for use in medicine |
| EP3820532A4 (en) | 2018-07-11 | 2022-04-06 | H. Lee Moffitt Cancer Center & Research Institute, Inc. | DIMERE IMMUNOMODULATORY COMPOUNDS AGAINST CEREBLON-BASED MECHANISMS |
| IT202000025423A1 (it) * | 2020-10-27 | 2022-04-27 | Ulisse Biomed S P A | Uso di proteine per il trattamento di patologie associate a tossine formanti pori o a proteine virali |
| US20250255934A1 (en) * | 2021-05-07 | 2025-08-14 | Lateral IP Pty Ltd | Compositions for treating inflammatory airway disease and uses thereof |
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|---|---|---|---|---|
| US2857386A (en) * | 1956-04-09 | 1958-10-21 | Ciba Pharm Prod Inc | Iso reserpic and iso deserpidic acids, salts and esters |
| US3119819A (en) * | 1959-07-29 | 1964-01-28 | Ciba Geigy Corp | Intermediates for 18-o-alkyl-reserpic acid esters and related compounds |
| FR1451176A (fr) * | 1962-01-11 | 1966-01-07 | Procédé de préparation de dérivés de l'acide nicotinique des acides alpha-amino-carboxyliques | |
| US3291800A (en) * | 1963-07-23 | 1966-12-13 | Warner Lambert Pharmaceutical | 3-substituted derivatives of yohimbane alkaloids and process for their production |
| US3264303A (en) * | 1964-04-06 | 1966-08-02 | Ciba Geigy Corp | Process for the manufacture of yohimbane-18-omicron-ethers |
| US4093709A (en) | 1975-01-28 | 1978-06-06 | Alza Corporation | Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates) |
| US4051842A (en) | 1975-09-15 | 1977-10-04 | International Medical Corporation | Electrode and interfacing pad for electrical physiological systems |
| HU172479B (hu) * | 1976-03-09 | 1978-09-28 | Gyogyszerkutato Intezet | Sposob poluchenija novykh soedinenij s ehrgolenovymi i |
| DE2626348C3 (de) | 1976-06-11 | 1980-01-31 | Siemens Ag, 1000 Berlin Und 8000 Muenchen | Implantierbare Dosiereinrichtung |
| NO812612L (no) | 1980-08-06 | 1982-02-08 | Ferring Pharma Ltd | Enzym-inhibitorer. |
| US4383529A (en) | 1980-11-03 | 1983-05-17 | Wescor, Inc. | Iontophoretic electrode device, method and gel insert |
| US4675189A (en) | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
| US4525359A (en) * | 1982-12-10 | 1985-06-25 | Greenway Frank L Iii | Treatment for selective weight control |
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| US4897255A (en) | 1985-01-14 | 1990-01-30 | Neorx Corporation | Metal radionuclide labeled proteins for diagnosis and therapy |
| US5175343A (en) | 1985-01-14 | 1992-12-29 | Neorx Corporation | Metal radionuclide labeled proteins for diagnosis and therapy |
| WO1986004334A1 (en) * | 1985-01-18 | 1986-07-31 | MERCK Patent Gesellschaft mit beschränkter Haftung | Immunoregulatory peptides |
| JPS62501502A (ja) * | 1985-01-18 | 1987-06-18 | イミユーンテツク・フアーマシユーテイカルズ | 免疫調節性ペプチド |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5045303A (en) | 1985-05-17 | 1991-09-03 | Neorx Corporation | Radiohalogenated small molecules for protein labeling |
| US4877868A (en) | 1986-03-12 | 1989-10-31 | Neorx Corporation | Radionuclide antibody coupling |
| US5560922A (en) | 1986-05-30 | 1996-10-01 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit using a polyacrylate adhesive polymer and process |
| US4879225A (en) | 1986-06-20 | 1989-11-07 | Neorx Corporation | Enhanced production of antibodies utilizing insolubilized immune complexes |
| US4863713A (en) | 1986-06-23 | 1989-09-05 | The Board Of Trustees Of Leland Stanford Jr. Univ. | Method and system for administering therapeutic and diagnostic agents |
| US5202118A (en) | 1987-12-18 | 1993-04-13 | Immunex Corporation | Method for promoting wound healing using IL-1 |
| US5091396A (en) | 1988-07-20 | 1992-02-25 | Monsanto Co. | Pyridyl peptide mimetic compounds which are useful platelet-aggregation inhibitors |
| US4992463A (en) | 1988-07-20 | 1991-02-12 | Monsanto Company | Thienyl peptide mimetic compounds which are useful in inhibiting platelet aggregation |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5028594A (en) * | 1988-12-27 | 1991-07-02 | Naxcor | Use of photodynamic compositions for cytotoxic effects |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5580774A (en) | 1989-07-31 | 1996-12-03 | Eli Lilly And Company | Chimeric antibodies directed against a human glycoprotein antigen |
| US5661132A (en) | 1989-12-14 | 1997-08-26 | Auragen, Inc. | Wound healing |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| ES2246502T3 (es) | 1990-08-29 | 2006-02-16 | Genpharm International, Inc. | Animales no humanos transgenicos capaces de producir anticuerpos heterologos. |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5650150A (en) | 1990-11-09 | 1997-07-22 | Gillies; Stephen D. | Recombinant antibody cytokine fusion proteins |
| US5824647A (en) * | 1990-12-12 | 1998-10-20 | Postlethwaite; Arnold E. | Chemotactic wound healing peptides |
| US5202169A (en) | 1991-01-23 | 1993-04-13 | Spendlove Max J | Releasable fastener, method of releasably fastening, and releasable fastener dispenser |
| CA2113990A1 (en) | 1991-07-26 | 1993-02-18 | Frederick L. Moolten | Cancer therapy utilizing malignant cells |
| US5326752A (en) * | 1991-11-27 | 1994-07-05 | Glycomed Incorporated | Substituted lactose and lactosamine derivatives as cell adhesion inhibitors |
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| US5578287A (en) | 1992-06-09 | 1996-11-26 | Neorx Corporation | Three-step pretargeting methods using improved biotin-active agent |
| US5616690A (en) | 1992-06-09 | 1997-04-01 | Neorx Corporation | Hexose derivatized human serum albumin clearing agents |
| CA2134239C (en) | 1992-06-09 | 2004-11-23 | Donald B. Axworthy | Pretargeting methods and compounds |
| WO1996040098A2 (en) | 1995-06-07 | 1996-12-19 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies with tamoxifen analogues |
| EP0710243B1 (en) | 1993-06-29 | 2000-06-14 | Ferring B.V. | Synthesis of cyclic peptides |
| JPH09505555A (ja) * | 1993-08-13 | 1997-06-03 | ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ,アズ リプレゼンテッド バイ ザ セクレタリー,デパートメント オブ ヘルス アンド ヒューマン サービシーズ | TGF−βの活性を刺激および阻害する方法および組成物 |
| US5459128A (en) * | 1993-11-12 | 1995-10-17 | Dana-Farber Cancer Institute | Human monocyte chemoattractant protein-1 (MCP-1) derivatives |
| CA2178477A1 (en) | 1993-12-07 | 1995-06-15 | Louis J. Theodore | Pretargeting methods and compounds |
| US5708163A (en) | 1994-03-15 | 1998-01-13 | Sloan-Kettering Institute Of Cancer Research | Synthesis of the breast tumor-associated antigen defined by monoclonalantibody MBRL and uses thereof |
| US6303120B1 (en) | 1994-03-15 | 2001-10-16 | Memorial Sloan-Kettering Institute For Cancer Research | Synthesis of glycoconjugates of the lewis y epitope and uses thereof |
| JP3447809B2 (ja) * | 1994-07-12 | 2003-09-16 | 花王株式会社 | 浴用剤 |
| WO1996029074A1 (en) * | 1995-03-22 | 1996-09-26 | Eli Lilly And Company | Methods of treating or preventing pain or nociception |
| US6265184B1 (en) | 1995-12-20 | 2001-07-24 | Icos Corporation | Polynucleotides encoding chemokine receptor 88C |
| WO1997029192A1 (en) | 1996-02-12 | 1997-08-14 | Schering Corporation | Mammalian dendritic cell chemokine reagents |
| US5667894A (en) | 1996-06-05 | 1997-09-16 | E. I. Du Pont De Nemours And Company | Cathodic electrocoating compositions containing methane sulfonic acid as a neutralizing agent |
| GB9617923D0 (en) | 1996-08-28 | 1996-10-09 | Smithkline Beecham Plc | Novel receptor |
| US5848956A (en) | 1997-03-18 | 1998-12-15 | Grettner; Norman L. | Multi-purpose lat sling |
| US6214540B1 (en) * | 1997-03-26 | 2001-04-10 | University Of Maryland Biotechnology Institute | Chemokines that inhibit immunodeficiency virus infection and methods based thereon |
| AU7583998A (en) | 1997-05-29 | 1998-12-30 | Zymogenetics Inc. | Human chemokine zchemo-8 |
| US6989435B2 (en) * | 1997-09-11 | 2006-01-24 | Cambridge University Technical Services Ltd. | Compounds and methods to inhibit or augment an inflammatory response |
| US5807482A (en) * | 1997-10-31 | 1998-09-15 | Uop Llc | Chiral stationary phase based on yohimbinic acid |
-
2000
- 2000-01-12 JP JP2000593637A patent/JP4712975B2/ja not_active Expired - Fee Related
- 2000-01-12 HK HK02100942.7A patent/HK1039784A1/zh unknown
- 2000-01-12 WO PCT/US2000/000821 patent/WO2000042071A2/en not_active Ceased
- 2000-01-12 CA CA2363067A patent/CA2363067C/en not_active Expired - Fee Related
- 2000-01-12 CA CA2697598A patent/CA2697598A1/en not_active Abandoned
- 2000-01-12 AU AU26100/00A patent/AU2610000A/en not_active Abandoned
- 2000-01-12 EP EP00904325A patent/EP1141011A2/en not_active Withdrawn
- 2000-01-12 EP EP10012546.7A patent/EP2386565A3/en not_active Withdrawn
-
2010
- 2010-03-01 JP JP2010043809A patent/JP5351078B2/ja not_active Expired - Fee Related
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