JP2005506151A5 - - Google Patents
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- Publication number
- JP2005506151A5 JP2005506151A5 JP2003537695A JP2003537695A JP2005506151A5 JP 2005506151 A5 JP2005506151 A5 JP 2005506151A5 JP 2003537695 A JP2003537695 A JP 2003537695A JP 2003537695 A JP2003537695 A JP 2003537695A JP 2005506151 A5 JP2005506151 A5 JP 2005506151A5
- Authority
- JP
- Japan
- Prior art keywords
- stent
- formula
- group
- compound
- thrombosis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims 9
- 238000000034 method Methods 0.000 claims 6
- 208000007536 Thrombosis Diseases 0.000 claims 5
- 208000037803 restenosis Diseases 0.000 claims 5
- 230000002265 prevention Effects 0.000 claims 4
- 229910052757 nitrogen Inorganic materials 0.000 claims 3
- KKJUPNGICOCCDW-UHFFFAOYSA-N 7-N,N-Dimethylamino-1,2,3,4,5-pentathiocyclooctane Chemical compound CN(C)C1CSSSSSC1 KKJUPNGICOCCDW-UHFFFAOYSA-N 0.000 claims 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 2
- 229910052801 chlorine Inorganic materials 0.000 claims 2
- 239000000460 chlorine Substances 0.000 claims 2
- 150000004677 hydrates Chemical class 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 238000007910 systemic administration Methods 0.000 claims 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 2
- IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical compound O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 claims 1
- YNSCKPCDFIDINW-UHFFFAOYSA-N 3-[[2-[[1-[2-(dimethylamino)acetyl]-6-methoxy-4,4-dimethyl-2,3-dihydroquinolin-7-yl]amino]-7h-pyrrolo[2,3-d]pyrimidin-4-yl]amino]thiophene-2-carboxamide Chemical group COC1=CC(C(CCN2C(=O)CN(C)C)(C)C)=C2C=C1NC(N=C1NC=CC1=1)=NC=1NC=1C=CSC=1C(N)=O YNSCKPCDFIDINW-UHFFFAOYSA-N 0.000 claims 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims 1
- 208000031481 Pathologic Constriction Diseases 0.000 claims 1
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical group C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 claims 1
- 210000001367 artery Anatomy 0.000 claims 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims 1
- 229910052794 bromium Inorganic materials 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 1
- 239000012876 carrier material Substances 0.000 claims 1
- 125000004093 cyano group Chemical group *C#N 0.000 claims 1
- 229910052731 fluorine Inorganic materials 0.000 claims 1
- 239000011737 fluorine Substances 0.000 claims 1
- 125000005842 heteroatom Chemical group 0.000 claims 1
- 125000000623 heterocyclic group Chemical group 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims 1
- 239000012528 membrane Substances 0.000 claims 1
- -1 nitro, amino Chemical group 0.000 claims 1
- 125000000843 phenylene group Chemical group C1(=C(C=CC=C1)*)* 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 claims 1
- 208000037804 stenosis Diseases 0.000 claims 1
- 230000036262 stenosis Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10152460A DE10152460A1 (de) | 2001-10-24 | 2001-10-24 | Stents |
| PCT/EP2002/011402 WO2003035133A1 (de) | 2001-10-24 | 2002-10-11 | Stents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005506151A JP2005506151A (ja) | 2005-03-03 |
| JP2005506151A5 true JP2005506151A5 (enExample) | 2006-01-05 |
Family
ID=7703557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003537695A Pending JP2005506151A (ja) | 2001-10-24 | 2002-10-11 | ステント |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US20050064006A1 (enExample) |
| EP (1) | EP1439869A1 (enExample) |
| JP (1) | JP2005506151A (enExample) |
| KR (1) | KR20040074977A (enExample) |
| CN (1) | CN1575189A (enExample) |
| AU (1) | AU2002340549B2 (enExample) |
| BR (1) | BR0213481A (enExample) |
| CA (1) | CA2464290A1 (enExample) |
| DE (1) | DE10152460A1 (enExample) |
| EC (1) | ECSP045075A (enExample) |
| EE (1) | EE200400080A (enExample) |
| HR (1) | HRP20040456A2 (enExample) |
| HU (1) | HUP0401760A3 (enExample) |
| IL (1) | IL161445A0 (enExample) |
| MA (1) | MA26341A1 (enExample) |
| MX (1) | MXPA04003755A (enExample) |
| NO (1) | NO20041984L (enExample) |
| NZ (1) | NZ532443A (enExample) |
| PL (1) | PL367968A1 (enExample) |
| RU (1) | RU2004115757A (enExample) |
| WO (1) | WO2003035133A1 (enExample) |
| ZA (1) | ZA200402989B (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19962924A1 (de) | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
| DE10129725A1 (de) * | 2001-06-20 | 2003-01-02 | Bayer Ag | Kombinationstherapie substituierter Oxazolidinone |
| DE10300111A1 (de) * | 2003-01-07 | 2004-07-15 | Bayer Healthcare Ag | Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid |
| DE10355461A1 (de) * | 2003-11-27 | 2005-06-23 | Bayer Healthcare Ag | Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung |
| DE102004062475A1 (de) * | 2004-12-24 | 2006-07-06 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung |
| EP1685841A1 (en) * | 2005-01-31 | 2006-08-02 | Bayer Health Care Aktiengesellschaft | Prevention and treatment of thromboembolic disorders |
| DE102005045518A1 (de) * | 2005-09-23 | 2007-03-29 | Bayer Healthcare Ag | 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung |
| DE102005047558A1 (de) * | 2005-10-04 | 2008-02-07 | Bayer Healthcare Ag | Kombinationstherapie substituierter Oxazolidinone zur Prophylaxe und Behandlung von cerebralen Durchblutungsstörungen |
| EP1934208B1 (de) | 2005-10-04 | 2011-03-23 | Bayer Schering Pharma Aktiengesellschaft | Neue polymorphe form von 5-chlor-n-({ ( 5s )-2-0x0-3-[4-( 3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl} -methyl)-2-thiophencarboxamid |
| DE102005047561A1 (de) | 2005-10-04 | 2007-04-05 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung |
| US20070097252A1 (en) * | 2005-10-31 | 2007-05-03 | Silverstein D A | Imaging methods, cameras, projectors, and articles of manufacture |
| DE102006034916A1 (de) * | 2006-07-28 | 2008-01-31 | Bayer Healthcare Ag | Beschichtung künstlicher Oberflächen von medizinischen Hilfsmitteln und Geräten sowie Reinigung und/oder Vorbehandlung von Kathetern und anderen medizinischen Hilfsmitteln und Geräten |
| DE102006051625A1 (de) * | 2006-11-02 | 2008-05-08 | Bayer Materialscience Ag | Kombinationstherapie substituierter Oxazolidinone |
| EP2220079A2 (en) * | 2007-11-15 | 2010-08-25 | Boehringer Ingelheim International GmbH | Substituted amides, manufacturing and use thereof as medicaments |
| CN116157164A (zh) * | 2020-05-26 | 2023-05-23 | 万能医药公司 | 抗凝剂化合物及其使用方法和装置 |
| US11654036B2 (en) | 2020-05-26 | 2023-05-23 | Elixir Medical Corporation | Anticoagulant compounds and methods and devices for their use |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE181735T1 (de) * | 1993-05-01 | 1999-07-15 | Merck Patent Gmbh | Substituierte 1-phenyl-oxazolidin-2-on derivate, deren herstellung und deren verwendung als adhäsionsrezeptor-antagonisten |
| EP0975659A1 (en) * | 1997-04-14 | 2000-02-02 | Cor Therapeutics, Inc. | SELECTIVE FACTOR Xa INHIBITORS |
| US6273913B1 (en) * | 1997-04-18 | 2001-08-14 | Cordis Corporation | Modified stent useful for delivery of drugs along stent strut |
| US20010029351A1 (en) * | 1998-04-16 | 2001-10-11 | Robert Falotico | Drug combinations and delivery devices for the prevention and treatment of vascular disease |
| DE19962924A1 (de) * | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
| DE10105989A1 (de) * | 2001-02-09 | 2002-08-14 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
-
2001
- 2001-10-24 DE DE10152460A patent/DE10152460A1/de not_active Withdrawn
-
2002
- 2002-02-11 IL IL16144502A patent/IL161445A0/xx unknown
- 2002-10-11 JP JP2003537695A patent/JP2005506151A/ja active Pending
- 2002-10-11 NZ NZ532443A patent/NZ532443A/en unknown
- 2002-10-11 AU AU2002340549A patent/AU2002340549B2/en not_active Ceased
- 2002-10-11 EP EP02774699A patent/EP1439869A1/de not_active Withdrawn
- 2002-10-11 US US10/493,552 patent/US20050064006A1/en not_active Abandoned
- 2002-10-11 PL PL02367968A patent/PL367968A1/xx not_active Application Discontinuation
- 2002-10-11 MX MXPA04003755A patent/MXPA04003755A/es not_active Application Discontinuation
- 2002-10-11 KR KR10-2004-7006051A patent/KR20040074977A/ko not_active Ceased
- 2002-10-11 CN CNA028210034A patent/CN1575189A/zh active Pending
- 2002-10-11 BR BR0213481-0A patent/BR0213481A/pt not_active IP Right Cessation
- 2002-10-11 RU RU2004115757/15A patent/RU2004115757A/ru not_active Application Discontinuation
- 2002-10-11 HU HU0401760A patent/HUP0401760A3/hu unknown
- 2002-10-11 EE EEP200400080A patent/EE200400080A/xx unknown
- 2002-10-11 HR HR20040456A patent/HRP20040456A2/hr not_active Application Discontinuation
- 2002-10-11 CA CA002464290A patent/CA2464290A1/en not_active Abandoned
- 2002-10-11 WO PCT/EP2002/011402 patent/WO2003035133A1/de not_active Ceased
-
2004
- 2004-04-20 ZA ZA200402989A patent/ZA200402989B/en unknown
- 2004-04-22 EC EC2004005075A patent/ECSP045075A/es unknown
- 2004-04-23 MA MA27648A patent/MA26341A1/fr unknown
- 2004-05-13 NO NO20041984A patent/NO20041984L/no not_active Application Discontinuation
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