|
US2671750A
(en)
*
|
1950-09-19 |
1954-03-09 |
Merck & Co Inc |
Stable noncaking aqueous suspension of cortisone acetate and method of preparing the same
|
|
US3536074A
(en)
*
|
1968-03-29 |
1970-10-27 |
Alfred Aufhauser |
Oral administration of a pill,tablet or capsule
|
|
US3959457A
(en)
*
|
1970-06-05 |
1976-05-25 |
Temple University |
Microparticulate material and method of making such material
|
|
JPS4932056B1
(https=)
*
|
1970-12-22 |
1974-08-27 |
|
|
|
US4073943A
(en)
*
|
1974-09-11 |
1978-02-14 |
Apoteksvarucentralen Vitrum Ab |
Method of enhancing the administration of pharmalogically active agents
|
|
US4107288A
(en)
*
|
1974-09-18 |
1978-08-15 |
Pharmaceutical Society Of Victoria |
Injectable compositions, nanoparticles useful therein, and process of manufacturing same
|
|
US4001200A
(en)
*
|
1975-02-27 |
1977-01-04 |
Alza Corporation |
Novel polymerized, cross-linked, stromal-free hemoglobin
|
|
US4001401A
(en)
*
|
1975-02-02 |
1977-01-04 |
Alza Corporation |
Blood substitute and blood plasma expander comprising polyhemoglobin
|
|
US4053590A
(en)
*
|
1975-02-27 |
1977-10-11 |
Alza Corporation |
Compositions of matter comprising macromolecular hemoglobin
|
|
DK143689C
(da)
*
|
1975-03-20 |
1982-03-15 |
J Kreuter |
Fremgangsmaade til fremstilling af en adsorberet vaccine
|
|
US4226248A
(en)
*
|
1978-10-26 |
1980-10-07 |
Manoli Samir H |
Phonocephalographic device
|
|
US4344934A
(en)
*
|
1978-11-20 |
1982-08-17 |
American Home Products Corporation |
Therapeutic compositions with enhanced bioavailability
|
|
DE3013839A1
(de)
*
|
1979-04-13 |
1980-10-30 |
Freunt Ind Co Ltd |
Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung
|
|
US4247406A
(en)
*
|
1979-04-23 |
1981-01-27 |
Widder Kenneth J |
Intravascularly-administrable, magnetically-localizable biodegradable carrier
|
|
US4316885A
(en)
*
|
1980-08-25 |
1982-02-23 |
Ayerst, Mckenna And Harrison, Inc. |
Acyl derivatives of rapamycin
|
|
US4534899A
(en)
*
|
1981-07-20 |
1985-08-13 |
Lipid Specialties, Inc. |
Synthetic phospholipid compounds
|
|
US4572203A
(en)
*
|
1983-01-27 |
1986-02-25 |
Feinstein Steven B |
Contact agents for ultrasonic imaging
|
|
US4718433A
(en)
*
|
1983-01-27 |
1988-01-12 |
Feinstein Steven B |
Contrast agents for ultrasonic imaging
|
|
US4725442A
(en)
*
|
1983-06-17 |
1988-02-16 |
Haynes Duncan H |
Microdroplets of water-insoluble drugs and injectable formulations containing same
|
|
US4671954A
(en)
*
|
1983-12-13 |
1987-06-09 |
University Of Florida |
Microspheres for incorporation of therapeutic substances and methods of preparation thereof
|
|
US4600531A
(en)
*
|
1984-06-27 |
1986-07-15 |
University Of Iowa Research Foundation |
Production of alpha-alpha cross-linked hemoglobins in high yield
|
|
US4598064A
(en)
*
|
1984-06-27 |
1986-07-01 |
University Of Iowa Research Foundation |
Alpha-alpha cross-linked hemoglobins
|
|
US4639364A
(en)
*
|
1984-11-14 |
1987-01-27 |
Mallinckrodt, Inc. |
Methods and compositions for enhancing magnetic resonance imaging
|
|
US4584130A
(en)
*
|
1985-03-29 |
1986-04-22 |
University Of Maryland |
Intramolecularly cross-linked hemoglobin and method of preparation
|
|
FR2608942B1
(fr)
*
|
1986-12-31 |
1991-01-11 |
Centre Nat Rech Scient |
Procede de preparation de systemes colloidaux dispersibles d'une substance, sous forme de nanocapsules
|
|
US5006650A
(en)
*
|
1987-02-11 |
1991-04-09 |
The Upjohn Company |
Novel N-1 substituted beta-lactams as antibiotics
|
|
US5723147A
(en)
*
|
1987-02-23 |
1998-03-03 |
Depotech Corporation |
Multivesicular liposomes having a biologically active substance encapsulated therein in the presence of a hydrochloride
|
|
JPH02502455A
(ja)
*
|
1987-02-27 |
1990-08-09 |
ジ・アップジョン・カンパニー |
ピリドンカルボン酸または酸誘導体を含有する抗生物質β‐ラクタム
|
|
US5015737A
(en)
*
|
1987-07-22 |
1991-05-14 |
The Upjohn Company |
Therapeutically useful beta-lactams
|
|
US4844882A
(en)
*
|
1987-12-29 |
1989-07-04 |
Molecular Biosystems, Inc. |
Concentrated stabilized microbubble-type ultrasonic imaging agent
|
|
US4929446A
(en)
*
|
1988-04-19 |
1990-05-29 |
American Cyanamid Company |
Unit dosage form
|
|
US4951673A
(en)
*
|
1988-08-19 |
1990-08-28 |
Alliance Pharmaceutical Corp. |
Magnetic resonance imaging with perfluorocarbon hydrides
|
|
US5041292A
(en)
*
|
1988-08-31 |
1991-08-20 |
Theratech, Inc. |
Biodegradable hydrogel matrices for the controlled release of pharmacologically active agents
|
|
US5114703A
(en)
*
|
1989-05-30 |
1992-05-19 |
Alliance Pharmaceutical Corp. |
Percutaneous lymphography using particulate fluorocarbon emulsions
|
|
GB8914060D0
(en)
*
|
1989-06-19 |
1989-08-09 |
Wellcome Found |
Agents for potentiating the effects of antitumour agents and combating multiple drug resistance
|
|
US5116599A
(en)
*
|
1989-07-31 |
1992-05-26 |
Johns Hopkins Univ. |
Perfluoro-t-butyl-containing compounds for use in fluorine-19 nmr and/or mri
|
|
FR2651680B1
(fr)
*
|
1989-09-14 |
1991-12-27 |
Medgenix Group Sa |
Nouveau procede de preparation de microparticules lipidiques.
|
|
JP2687245B2
(ja)
*
|
1989-09-29 |
1997-12-08 |
富士写真フイルム株式会社 |
磁気記録媒体の製造方法
|
|
US5250283A
(en)
*
|
1990-03-28 |
1993-10-05 |
Molecular Biosystems, Inc. |
Organic contrast agent analog and method of making same
|
|
US5091188A
(en)
*
|
1990-04-26 |
1992-02-25 |
Haynes Duncan H |
Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs
|
|
CA2019719A1
(en)
*
|
1990-06-25 |
1991-12-25 |
William J. Thompson |
Mouthwash
|
|
US5059699A
(en)
*
|
1990-08-28 |
1991-10-22 |
Virginia Tech Intellectual Properties, Inc. |
Water soluble derivatives of taxol
|
|
US5110606A
(en)
*
|
1990-11-13 |
1992-05-05 |
Affinity Biotech, Inc. |
Non-aqueous microemulsions for drug delivery
|
|
US5145684A
(en)
*
|
1991-01-25 |
1992-09-08 |
Sterling Drug Inc. |
Surface modified drug nanoparticles
|
|
US5399363A
(en)
*
|
1991-01-25 |
1995-03-21 |
Eastman Kodak Company |
Surface modified anticancer nanoparticles
|
|
AU642066B2
(en)
*
|
1991-01-25 |
1993-10-07 |
Nanosystems L.L.C. |
X-ray contrast compositions useful in medical imaging
|
|
US5143716A
(en)
*
|
1991-02-01 |
1992-09-01 |
Unger Evan C |
Phosphorylated sugar alcohols, Mono- and Di-Saccharides as contrast agents for use in magnetic resonance imaging of the gastrointestinal region
|
|
US5416071A
(en)
*
|
1991-03-12 |
1995-05-16 |
Takeda Chemical Industries, Ltd. |
Water-soluble composition for sustained-release containing epo and hyaluronic acid
|
|
US5434143A
(en)
*
|
1991-05-10 |
1995-07-18 |
Boron Biologicals, Inc. |
Pharmaceutical compositions comprising phosphite-borane compounds
|
|
GB9111580D0
(en)
*
|
1991-05-30 |
1991-07-24 |
Wellcome Found |
Nucleoside derivative
|
|
US5442062A
(en)
*
|
1991-10-24 |
1995-08-15 |
The Upjohn Company |
Imidazole derivatives and pharmaceutical compositions containing the same
|
|
US5292650A
(en)
*
|
1991-10-29 |
1994-03-08 |
Eli Lilly And Company |
Preparation of hapalindole-related alkaloids from blue-green algae
|
|
EP0706373B1
(en)
*
|
1992-03-23 |
2000-07-19 |
Georgetown University |
Liposome encapsulated taxol and a method of using the same
|
|
CA2086874E
(en)
*
|
1992-08-03 |
2000-01-04 |
Renzo Mauro Canetta |
Methods for administration of taxol
|
|
NZ248813A
(en)
*
|
1992-11-25 |
1995-06-27 |
Eastman Kodak Co |
Polymeric grinding media used in grinding pharmaceutical substances
|
|
US5298262A
(en)
*
|
1992-12-04 |
1994-03-29 |
Sterling Winthrop Inc. |
Use of ionic cloud point modifiers to prevent particle aggregation during sterilization
|
|
US5302401A
(en)
*
|
1992-12-09 |
1994-04-12 |
Sterling Winthrop Inc. |
Method to reduce particle size growth during lyophilization
|
|
US5429824A
(en)
*
|
1992-12-15 |
1995-07-04 |
Eastman Kodak Company |
Use of tyloxapole as a nanoparticle stabilizer and dispersant
|
|
US5326552A
(en)
*
|
1992-12-17 |
1994-07-05 |
Sterling Winthrop Inc. |
Formulations for nanoparticulate x-ray blood pool contrast agents using high molecular weight nonionic surfactants
|
|
US5401492A
(en)
*
|
1992-12-17 |
1995-03-28 |
Sterling Winthrop, Inc. |
Water insoluble non-magnetic manganese particles as magnetic resonance contract enhancement agents
|
|
US5439686A
(en)
*
|
1993-02-22 |
1995-08-08 |
Vivorx Pharmaceuticals, Inc. |
Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
|
|
BR9405798A
(pt)
*
|
1993-02-22 |
1995-12-12 |
Vivorx Pharmaceuticals Inc |
Métodos para liberação in vivo de material biológico e composições úteis dos mesmos
|
|
US5362478A
(en)
*
|
1993-03-26 |
1994-11-08 |
Vivorx Pharmaceuticals, Inc. |
Magnetic resonance imaging with fluorocarbons encapsulated in a cross-linked polymeric shell
|
|
US5916596A
(en)
*
|
1993-02-22 |
1999-06-29 |
Vivorx Pharmaceuticals, Inc. |
Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
|
|
US6096331A
(en)
*
|
1993-02-22 |
2000-08-01 |
Vivorx Pharmaceuticals, Inc. |
Methods and compositions useful for administration of chemotherapeutic agents
|
|
US6537579B1
(en)
*
|
1993-02-22 |
2003-03-25 |
American Bioscience, Inc. |
Compositions and methods for administration of pharmacologically active compounds
|
|
US6749868B1
(en)
*
|
1993-02-22 |
2004-06-15 |
American Bioscience, Inc. |
Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
|
|
US6753006B1
(en)
*
|
1993-02-22 |
2004-06-22 |
American Bioscience, Inc. |
Paclitaxel-containing formulations
|
|
US5665382A
(en)
*
|
1993-02-22 |
1997-09-09 |
Vivorx Pharmaceuticals, Inc. |
Methods for the preparation of pharmaceutically active agents for in vivo delivery
|
|
US5395619A
(en)
*
|
1993-03-03 |
1995-03-07 |
Liposome Technology, Inc. |
Lipid-polymer conjugates and liposomes
|
|
US5264610A
(en)
*
|
1993-03-29 |
1993-11-23 |
Sterling Winthrop Inc. |
Iodinated aromatic propanedioates
|
|
TW406020B
(en)
*
|
1993-09-29 |
2000-09-21 |
Bristol Myers Squibb Co |
Stabilized pharmaceutical composition and its method for preparation and stabilizing solvent
|
|
US5766627A
(en)
*
|
1993-11-16 |
1998-06-16 |
Depotech |
Multivescular liposomes with controlled release of encapsulated biologically active substances
|
|
US5731334A
(en)
*
|
1994-01-11 |
1998-03-24 |
The Scripps Research Institute |
Method for treating cancer using taxoid onium salt prodrugs
|
|
FI955320A7
(fi)
*
|
1994-03-07 |
1995-11-24 |
Univ Michigan |
Bioaktiivisia ja/tai kohdennettuja dendriimikonjugaatteja
|
|
US5565478A
(en)
*
|
1994-03-14 |
1996-10-15 |
The United States Of America As Represented By The Department Of Health & Human Services |
Combination therapy using signal transduction inhibitors with paclitaxel and other taxane analogs
|
|
GB9405593D0
(en)
*
|
1994-03-22 |
1994-05-11 |
Zeneca Ltd |
Pharmaceutical compositions
|
|
US5731356A
(en)
*
|
1994-03-22 |
1998-03-24 |
Zeneca Limited |
Pharmaceutical compositions of propofol and edetate
|
|
TW384224B
(en)
*
|
1994-05-25 |
2000-03-11 |
Nano Sys Llc |
Method of preparing submicron particles of a therapeutic or diagnostic agent
|
|
US5718388A
(en)
*
|
1994-05-25 |
1998-02-17 |
Eastman Kodak |
Continuous method of grinding pharmaceutical substances
|
|
US5543152A
(en)
*
|
1994-06-20 |
1996-08-06 |
Inex Pharmaceuticals Corporation |
Sphingosomes for enhanced drug delivery
|
|
US5626862A
(en)
*
|
1994-08-02 |
1997-05-06 |
Massachusetts Institute Of Technology |
Controlled local delivery of chemotherapeutic agents for treating solid tumors
|
|
US5628981A
(en)
*
|
1994-12-30 |
1997-05-13 |
Nano Systems L.L.C. |
Formulations of oral gastrointestinal diagnostic x-ray contrast agents and oral gastrointestinal therapeutic agents
|
|
US5518738A
(en)
*
|
1995-02-09 |
1996-05-21 |
Nanosystem L.L.C. |
Nanoparticulate nsaid compositions
|
|
US5622938A
(en)
*
|
1995-02-09 |
1997-04-22 |
Nano Systems L.L.C. |
Sugar base surfactant for nanocrystals
|
|
US5593657A
(en)
*
|
1995-02-09 |
1997-01-14 |
Nanosystems L.L.C. |
Barium salt formulations stabilized by non-ionic and anionic stabilizers
|
|
US5591456A
(en)
*
|
1995-02-10 |
1997-01-07 |
Nanosystems L.L.C. |
Milled naproxen with hydroxypropyl cellulose as a dispersion stabilizer
|
|
US5500204A
(en)
*
|
1995-02-10 |
1996-03-19 |
Eastman Kodak Company |
Nanoparticulate diagnostic dimers as x-ray contrast agents for blood pool and lymphatic system imaging
|
|
US5510118A
(en)
*
|
1995-02-14 |
1996-04-23 |
Nanosystems Llc |
Process for preparing therapeutic compositions containing nanoparticles
|
|
US5528328A
(en)
*
|
1995-02-21 |
1996-06-18 |
O'farrill; Dave |
Camera filter quick release adapter
|
|
US5718919A
(en)
*
|
1995-02-24 |
1998-02-17 |
Nanosystems L.L.C. |
Nanoparticles containing the R(-)enantiomer of ibuprofen
|
|
CA2213638C
(en)
*
|
1995-02-24 |
2004-05-04 |
Nanosystems L.L.C. |
Aerosols containing nanoparticle dispersions
|
|
US5747001A
(en)
*
|
1995-02-24 |
1998-05-05 |
Nanosystems, L.L.C. |
Aerosols containing beclomethazone nanoparticle dispersions
|
|
US5643552A
(en)
*
|
1995-03-09 |
1997-07-01 |
Nanosystems L.L.C. |
Nanoparticulate diagnostic mixed carbonic anhydrides as x-ray contrast agents for blood pool and lymphatic system imaging
|
|
US5521218A
(en)
*
|
1995-05-15 |
1996-05-28 |
Nanosystems L.L.C. |
Nanoparticulate iodipamide derivatives for use as x-ray contrast agents
|
|
US5635406A
(en)
*
|
1995-06-07 |
1997-06-03 |
Abbott Laboratories |
Stabilized standards and calibrators containing rapamycin and tacrolimus bound to anti-rapamycin and anti-tacrolimus antibodies
|
|
EP0833828B1
(en)
*
|
1995-06-09 |
2002-11-20 |
Novartis AG |
Rapamycin derivatives
|
|
GB9515214D0
(en)
*
|
1995-07-25 |
1995-09-20 |
Univ Strathclyde |
Plant extracts
|
|
US5962019A
(en)
*
|
1995-08-25 |
1999-10-05 |
Sangstat Medical Corporation |
Oral cyclosporin formulations
|
|
US5834025A
(en)
*
|
1995-09-29 |
1998-11-10 |
Nanosystems L.L.C. |
Reduction of intravenously administered nanoparticulate-formulation-induced adverse physiological reactions
|
|
US5631741A
(en)
*
|
1995-12-29 |
1997-05-20 |
Intel Corporation |
Electronic carbon paper
|
|
ES2205072T3
(es)
*
|
1996-01-03 |
2004-05-01 |
Smithkline Beecham Plc |
Derivados carbamoiloxi de mutilina y su uso como agentes antibacterianos.
|
|
US5744460A
(en)
*
|
1996-03-07 |
1998-04-28 |
Novartis Corporation |
Combination for treatment of proliferative diseases
|
|
US5637625A
(en)
*
|
1996-03-19 |
1997-06-10 |
Research Triangle Pharmaceuticals Ltd. |
Propofol microdroplet formulations
|
|
EP1208847B8
(en)
*
|
1996-07-30 |
2007-02-14 |
Novartis AG |
Pharmaceutical compositions for the treatment of transplant rejection, as well as autoimmune or inflammatory conditions
|
|
RU2186562C2
(ru)
*
|
1996-08-22 |
2002-08-10 |
Ресеч Трайангл Фармасьютикалс Лтд. |
Композиции, представляющие собой микрочастицы веществ, нерастворимых в воде, и способ их изготовления
|
|
US6458373B1
(en)
*
|
1997-01-07 |
2002-10-01 |
Sonus Pharmaceuticals, Inc. |
Emulsion vehicle for poorly soluble drugs
|
|
US6051563A
(en)
*
|
1997-02-12 |
2000-04-18 |
U.S. Bioscience, Inc. |
Methods for the administration of amifostine and related compounds
|
|
US6045829A
(en)
*
|
1997-02-13 |
2000-04-04 |
Elan Pharma International Limited |
Nanocrystalline formulations of human immunodeficiency virus (HIV) protease inhibitors using cellulosic surface stabilizers
|
|
WO1998035666A1
(en)
*
|
1997-02-13 |
1998-08-20 |
Nanosystems Llc |
Formulations of nanoparticle naproxen tablets
|
|
US5989591A
(en)
*
|
1997-03-14 |
1999-11-23 |
American Home Products Corporation |
Rapamycin formulations for oral administration
|
|
CA2322444A1
(en)
*
|
1998-03-05 |
1999-09-10 |
Agouron Pharmaceuticals, Inc. |
Non-peptide gnrh agents
|
|
IL138765A0
(en)
*
|
1998-03-30 |
2001-10-31 |
Rtp Pharma Inc |
Compositions containing microparticles of water-insoluble substances and method for their preparation
|
|
US6228985B1
(en)
*
|
1998-05-21 |
2001-05-08 |
Schering Corporation |
Derivatives of aminobenzoic and aminobiphenylcarboxylic acids useful as anti-cancer agents
|
|
US5962536A
(en)
*
|
1998-07-31 |
1999-10-05 |
Komer; Gene |
Injectable propofol formulations
|
|
US6028108A
(en)
*
|
1998-10-22 |
2000-02-22 |
America Home Products Corporation |
Propofol composition comprising pentetate
|
|
US6140373A
(en)
*
|
1998-10-23 |
2000-10-31 |
Abbott Laboratories |
Propofol composition
|
|
US6428814B1
(en)
*
|
1999-10-08 |
2002-08-06 |
Elan Pharma International Ltd. |
Bioadhesive nanoparticulate compositions having cationic surface stabilizers
|
|
US6071952A
(en)
*
|
1998-12-02 |
2000-06-06 |
Mylan Pharmaceuticals, Inc. |
Stabilized injectable pharmaceutical compositions containing taxoid anti-neoplastic agents
|
|
US6225311B1
(en)
*
|
1999-01-27 |
2001-05-01 |
American Cyanamid Company |
Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors
|
|
US6200085B1
(en)
*
|
1999-03-08 |
2001-03-13 |
Stuart Gee |
Transport system for farm combines and other large vehicles
|
|
US6267989B1
(en)
*
|
1999-03-08 |
2001-07-31 |
Klan Pharma International Ltd. |
Methods for preventing crystal growth and particle aggregation in nanoparticulate compositions
|
|
US6177477B1
(en)
*
|
1999-03-24 |
2001-01-23 |
American Home Products Corporation |
Propofol formulation containing TRIS
|
|
US6100302A
(en)
*
|
1999-04-05 |
2000-08-08 |
Baxter International Inc. |
Propofol formulation with enhanced microbial characteristics
|
|
US6362234B1
(en)
*
|
2000-08-15 |
2002-03-26 |
Vyrex Corporation |
Water-soluble prodrugs of propofol for treatment of migrane
|
|
US6399087B1
(en)
*
|
2000-12-20 |
2002-06-04 |
Amphastar Pharmaceuticals, Inc. |
Propofol formulation with enhanced microbial inhibition
|
|
EP1490030B2
(en)
*
|
2002-03-20 |
2010-07-14 |
Elan Pharma International Limited |
Nanoparticulate compositions of angiogenesis inhibitors
|
|
AU2005307797B2
(en)
*
|
2004-11-16 |
2011-06-02 |
Alkermes Pharma Ireland Limited |
Injectable nanoparticulate olanzapine formulations
|
|
SE530813C2
(sv)
*
|
2007-01-31 |
2008-09-16 |
Tolerans Ab |
Förfarande och anordning vid en rotationshäftmaskin
|