JP2005505545A - 高血圧及び心不全を減少させる方法 - Google Patents

高血圧及び心不全を減少させる方法 Download PDF

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JP2005505545A
JP2005505545A JP2003524516A JP2003524516A JP2005505545A JP 2005505545 A JP2005505545 A JP 2005505545A JP 2003524516 A JP2003524516 A JP 2003524516A JP 2003524516 A JP2003524516 A JP 2003524516A JP 2005505545 A JP2005505545 A JP 2005505545A
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heart
tyrphostin
hypertension
hypertrophy
ischemia
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JP2003524516A
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Japanese (ja)
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JP2005505545A5 (https=
Inventor
エム エイ キュー シッディキ
エデュアード マスカレノ
ダニエル エル ベックルズ
Original Assignee
ザ リサーチ ファウンデーション オブ ステイト ユニヴァーシティ オブ ニューヨーク
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Publication of JP2005505545A publication Critical patent/JP2005505545A/ja
Publication of JP2005505545A5 publication Critical patent/JP2005505545A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • A61K31/277Nitriles; Isonitriles having a ring, e.g. verapamil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2003524516A 2001-08-31 2002-07-23 高血圧及び心不全を減少させる方法 Pending JP2005505545A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/945,192 US6433018B1 (en) 2001-08-31 2001-08-31 Method for reducing hypertrophy and ischemia
PCT/US2002/023444 WO2003020202A2 (en) 2001-08-31 2002-07-23 Method for reducing hypertension and heart failure

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010180146A Division JP2010285455A (ja) 2001-08-31 2010-08-11 高血圧及び心不全を減少させる方法

Publications (2)

Publication Number Publication Date
JP2005505545A true JP2005505545A (ja) 2005-02-24
JP2005505545A5 JP2005505545A5 (https=) 2006-01-05

Family

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JP2003524516A Pending JP2005505545A (ja) 2001-08-31 2002-07-23 高血圧及び心不全を減少させる方法
JP2010180146A Pending JP2010285455A (ja) 2001-08-31 2010-08-11 高血圧及び心不全を減少させる方法

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JP2010180146A Pending JP2010285455A (ja) 2001-08-31 2010-08-11 高血圧及び心不全を減少させる方法

Country Status (11)

Country Link
US (2) US6433018B1 (https=)
EP (1) EP1427401A4 (https=)
JP (2) JP2005505545A (https=)
KR (1) KR20040050894A (https=)
AU (1) AU2002313700B2 (https=)
BR (1) BR0212252A (https=)
CA (1) CA2458798C (https=)
MX (1) MXPA04001913A (https=)
NZ (1) NZ531693A (https=)
WO (1) WO2003020202A2 (https=)
ZA (1) ZA200402540B (https=)

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JP2011126258A (ja) * 2009-12-21 2011-06-30 Panasonic Electric Works Co Ltd 繊維ボードの製造方法

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WO2005012294A1 (en) * 2003-07-30 2005-02-10 Rigel Pharmaceuticals, Inc. 2,4-pyrimidinediamine compounds for use in the treatment or prevention of autoimmune diseases
US20050130893A1 (en) * 2003-09-30 2005-06-16 Joan Smith-Sonneborn Use of opioids in prevention of and recovery from a stress-induced crash in blood pressure
MXPA06006460A (es) 2003-12-11 2006-08-23 Univ Texas Compuestos para el tratamiento de enfermedades proliferativas celulares.
TWI398261B (zh) * 2003-12-17 2013-06-11 Alcon Inc 血清類澱粉a基因於診斷及治療青光眼及鑑定抗青光眼劑上之用途
US7662389B2 (en) * 2003-12-17 2010-02-16 Alcon, Inc. Use of serum amyloid A gene in diagnosis and treatment of glaucoma and identification of anti-glaucoma agents
US20100113481A1 (en) * 2003-12-17 2010-05-06 Alcon Research, Ltd. Use of serum amyloid a gene in diagnosis and treatment of glaucoma and identification of anti-glaucoma agents
WO2006044694A2 (en) * 2004-10-15 2006-04-27 Palo Alto Investors Methods and compositions for treating a disease condition in a subject
US20070203161A1 (en) * 2006-02-24 2007-08-30 Rigel Pharmaceuticals, Inc. Compositions and methods for inhibition of the jak pathway
BRPI0610876B8 (pt) 2005-06-08 2021-05-25 Rigel Pharmaceuticals Inc composto, formulação farmacêutica, e métodos de inibir uma atividade de uma jak cinase, e de inibir uma cascata de transdução de sinal em que jak3 cinase desempenha um papel
WO2007058627A1 (en) 2005-11-16 2007-05-24 S*Bio Pte Ltd Oxygen linked pyrimidine derivatives
US10517876B2 (en) 2005-11-16 2019-12-31 Cti Biopharma Corp. Oxygen linked pyrimidine derivatives
EP1983848A2 (en) * 2006-01-13 2008-10-29 The President and Fellows of Harvard College Xenohormesis based compositions and methods
ES2622493T3 (es) * 2006-02-24 2017-07-06 Rigel Pharmaceuticals, Inc. Composiciones y métodos para la inhibición de la ruta de JAK
BRPI0708347A2 (pt) * 2006-02-28 2011-05-24 Cytopia Res Pty Ltd inibição jak2 como um tratamento da hipertensão arterial pulmonar
RU2456265C2 (ru) * 2006-03-31 2012-07-20 Дзе Борд Оф Риджентс Оф Дзе Юниверсити Оф Техас Систем Биологически доступная для перорального применения кофейная кислота, относящаяся к противоопухолевым лекарственным средствам
KR101566840B1 (ko) 2007-03-12 2015-11-06 와이엠 바이오사이언시즈 오스트레일리아 피티와이 엘티디 페닐 아미노 피리미딘 화합물 및 이의 용도
HUE030912T2 (en) 2008-02-15 2017-06-28 Rigel Pharmaceuticals Inc Pyrimidine-2-amine compounds and their use as inhibitors of yak kinases
US8063058B2 (en) 2008-04-16 2011-11-22 Portola Pharmaceuticals, Inc. Inhibitors of syk and JAK protein kinases
US8138339B2 (en) 2008-04-16 2012-03-20 Portola Pharmaceuticals, Inc. Inhibitors of protein kinases
AU2009238590A1 (en) * 2008-04-22 2009-10-29 Portola Pharmaceuticals, Inc. Inhibitors of protein kinases
US10517839B2 (en) * 2008-06-09 2019-12-31 Cornell University Mast cell inhibition in diseases of the retina and vitreous
AU2009268841B2 (en) 2008-07-08 2014-02-06 Board Of Regents, The University Of Texas System Novel inhibitors of proliferation and activation of signal transducer and activator of transcription (STATS)
PL2376499T3 (pl) 2008-12-11 2015-07-31 Cti Biopharma Corp Sól cytrynianowa 11-(2-pirrolidyn-1-yloetoksy)-14,19-dioksa-5,7,26-triazatetracyklo[19.3.1.1(2,6).1(8,12)]heptakosa-1(25),2(26),3,5,8,10,12(27),16,21,23-dekaenu
CN106420756A (zh) * 2009-07-28 2017-02-22 里格尔药品股份有限公司 抑制jak途径的组合物和方法
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011126258A (ja) * 2009-12-21 2011-06-30 Panasonic Electric Works Co Ltd 繊維ボードの製造方法

Also Published As

Publication number Publication date
AU2002313700B2 (en) 2007-04-26
WO2003020202A2 (en) 2003-03-13
CA2458798C (en) 2013-06-25
JP2010285455A (ja) 2010-12-24
NZ531693A (en) 2006-05-26
US20040266661A1 (en) 2004-12-30
MXPA04001913A (es) 2004-06-18
EP1427401A2 (en) 2004-06-16
WO2003020202A3 (en) 2003-08-28
ZA200402540B (en) 2005-06-29
EP1427401A4 (en) 2009-04-29
US6433018B1 (en) 2002-08-13
CA2458798A1 (en) 2003-03-13
KR20040050894A (ko) 2004-06-17
US7235588B2 (en) 2007-06-26
BR0212252A (pt) 2004-09-14

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