JP2005502672A5 - - Google Patents

Info

Publication number

JP2005502672A5

JP2005502672A5 JP2003524529A JP2003524529A JP2005502672A5 JP 2005502672 A5 JP2005502672 A5 JP 2005502672A5 JP 2003524529 A JP2003524529 A JP 2003524529A JP 2003524529 A JP2003524529 A JP 2003524529A JP 2005502672 A5 JP2005502672 A5 JP 2005502672A5

Authority

JP

Japan

Prior art keywords

composition

polypeptide

angiogenic

composition according

coronary artery

Prior art date

2002-08-29

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
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• 229920001184 polypeptide Polymers 0.000 claims 6
• 108090000765 processed proteins & peptides Proteins 0.000 claims 6
• 102000004196 processed proteins & peptides Human genes 0.000 claims 6
• 230000002491 angiogenic effect Effects 0.000 claims 4
• 230000003110 anti-inflammatory effect Effects 0.000 claims 4
• 210000004351 coronary vessel Anatomy 0.000 claims 3
• 230000006378 damage Effects 0.000 claims 3
• UGPMCIBIHRSCBV-XNBOLLIBSA-N Thymosin beta 4 Chemical group N([C@@H](CC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(O)=O)C(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(C)=O UGPMCIBIHRSCBV-XNBOLLIBSA-N 0.000 claims 2
• 102100035000 Thymosin beta-4 Human genes 0.000 claims 2
• 125000003275 alpha amino acid group Chemical group 0.000 claims 2
• 230000035876 healing Effects 0.000 claims 2
• 230000002265 prevention Effects 0.000 claims 2
• 230000001737 promoting effect Effects 0.000 claims 2
• 239000000126 substance Substances 0.000 claims 2
• 108010079996 thymosin beta(4) Proteins 0.000 claims 2
• 102000001708 Protein Isoforms Human genes 0.000 claims 1
• 108010029485 Protein Isoforms Proteins 0.000 claims 1
• 239000005557 antagonist Substances 0.000 claims 1
• 210000004899 c-terminal region Anatomy 0.000 claims 1
• 208000037891 myocardial injury Diseases 0.000 claims 1
• 150000003462 sulfoxides Chemical class 0.000 claims 1